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Specialty: Cardiology
Condition: Metabolic Syndrome

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Total 151 results found since Jan 2013.

Relationship of Lipoproteins to Cardiovascular Events The AIM-HIGH Trial (Atherothrombosis Intervention in Metabolic Syndrome With Low HDL/High Triglycerides and Impact on Global Health Outcomes)
This study sought to examine the relationship between niacin treatment, lipoproteins, and cardiovascular (CV) outcomes in this secondary analysis of the AIM-HIGH (Atherothrombosis Intervention in Metabolic Syndrome With Low HDL/High Triglycerides and Impact on Global Health Outcomes) trial.BackgroundDuring a 3-year follow-up in 3,414 patients with established CV disease and low high-density lipoprotein cholesterol (HDL-C) levels, combined niacin + low-density lipoprotein cholesterol (LDL-C)–lowering therapy did not reduce CV events compared with LDL-C–lowering therapy alone.MethodsSubjects taking simvastatin and/or ez...
Source: Journal of the American College of Cardiology: Cardiovascular Interventions - October 14, 2013 Category: Cardiology Source Type: research

Relationship of Lipoproteins to Cardiovascular Events: The AIM-HIGH Trial (Atherothrombosis Intervention in Metabolic Syndrome With Low HDL/High Triglycerides and Impact on Global Health Outcomes)
This study sought to examine the relationship between niacin treatment, lipoproteins, and cardiovascular (CV) outcomes in this secondary analysis of the AIM-HIGH (Atherothrombosis Intervention in Metabolic Syndrome With Low HDL/High Triglycerides and Impact on Global Health Outcomes) trial.Background: During a 3-year follow-up in 3,414 patients with established CV disease and low high-density lipoprotein cholesterol (HDL-C) levels, combined niacin + low-density lipoprotein cholesterol (LDL-C)–lowering therapy did not reduce CV events compared with LDL-C–lowering therapy alone.Methods: Subjects taking simvastatin and/o...
Source: Journal of the American College of Cardiology - August 2, 2013 Category: Cardiology Authors: John R. Guyton, April E. Slee, Todd Anderson, Jerome L. Fleg, Ronald B. Goldberg, Moti L. Kashyap, Santica M. Marcovina, Stephen D. Nash, Kevin D. O'Brien, William S. Weintraub, Ping Xu, Xue-Qiao Zhao, William E. Boden Tags: Cardiometabolic Risk Source Type: research

Association of soy food intake with risk and biomarkers of coronary heart disease in Chinese men
Soy food intake has been associated with a reduced risk of coronary heart disease (CHD) in women, but its association with CHD in men is unclear . Several studies have found sex differences in the associations of soy intake with metabolic syndrome, endothelial function, and other cardiovascular risk factors . In the Shanghai Men's Health Study , we investigated the association between soy food intake and incident CHD among 55,474 Chinese men (40–74years) who were free of CHD, stroke, and cancer at baseline (2002–2006). We also examined the associations of soy intake with multiple CHD biomarkers in a subsample of 3885 m...
Source: International Journal of Cardiology - January 21, 2014 Category: Cardiology Authors: Danxia Yu, Xianglan Zhang, Yong-Bing Xiang, Gong Yang, Honglan Li, Sergio Fazio, MacRae Linton, Qiuyin Cai, Wei Zheng, Yu-Tang Gao, Xiao-Ou Shu Tags: Online Letters to the Editor Source Type: research

Abstract 185: The Sex Gap among Cardiovascular Disease Encounters in India Session Title: Poster Session I
Conclusion: Untreated or poorly managed AF and CAD can lead to myocardial infarction, stroke and death. A greater awareness of gender differences in AF and CAD, and the impact of factors that are unique to each gender, would contribute to more effective management and better long-term outcomes.Though genetic differences may contribute to greater cardiovascular disease prevalence in men, PINNACLE India’s sizable difference in male and female representation could be indicative of cultural or economic issues limiting access to specialty care for females. Implementing dedicated efforts to understand and reduce gaps in ac...
Source: Circulation: Cardiovascular Quality and Outcomes - June 2, 2014 Category: Cardiology Authors: Vicera, V. D., Glusenkamp, N. T., Risch, S. A., Kerkar, P., Kumar, G., Oetgen, W. J. Tags: Session Title: Poster Session I Source Type: research

Metabolic syndrome in the prediction of cardiovascular events: the potential additive role of hsCRP and adiponectin
Conclusions MS is an important predictor of cardiovascular events and is most harmful in combination with high plasma hsCRP. The clustering of components is especially harmful.
Source: European Journal of Preventive Cardiology - September 16, 2014 Category: Cardiology Authors: Santaniemi, M., Ukkola, O., Malo, E., Bloigu, R., Kesaniemi, Y. A. Tags: Original scientific papers Source Type: research

Echocardiography as a Marker of Cardiac end Organ Injury at a Young age
Abstract Coronary heart disease and stroke are two leading causes of morbidity and mortality. Risk factors have included obesity, metabolic syndrome, hypertension, and diabetes mellitus, and they appear to influence left ventricular mass, geometry, and systolic and diastolic function as well as left atrial size. Echocardiography is a non-invasive tool to assess these effects in children and should be utilized as a preventive as well as a diagnostic modality, as measurements from echocardiography may define an intermediate phenotype between risk and clinical endpoints. Information regarding the pathophysiologic me...
Source: Current Cardiovascular Risk Reports - April 2, 2014 Category: Cardiology Source Type: research

Metabolic syndrome, diabetes mellitus, or both and cardiovascular risk in outpatients with or at risk for atherothrombosis
Conclusions In the REACH registry, presence of newly detected DM but not metabolic syndrome was associated with an increased risk of cardiovascular events.
Source: European Journal of Preventive Cardiology - November 14, 2014 Category: Cardiology Authors: Udell, J. A., Steg, P. G., Scirica, B. M., Eagle, K. A., Ohman, E. M., Goto, S., Alsheikh-Ali, A. A., Porath, A., Corbalan, R., Umez-Eronini, A. A., Hoffman, E. B., Wilson, P. W., Bhatt, D. L., on Behalf of the Reduction of Atherothrombosis for Continued Tags: Original scientific papers Source Type: research

Importance of Sex and Gender in atherosclerosis and cardiovascular disease
In this special issue of the journal, there are papers on bone health and coronary artery calcification, age and sex differences in the effect of parental stroke on the progression of carotid intima-media thickness, macrophage subsets in the adipose tissue by sex and by reproductive age of women, uric acid levels and metabolic syndrome, sex differences in cardiovascular risk factors and disease prevention, severity of stable coronary artery disease and its biomarkers, cardiovascular disease and autoimmune diseases genetics of cardiovascular disease, outcome after CABG; association of serum phosphorus with subclinical ather...
Source: Atherosclerosis - April 29, 2015 Category: Cardiology Authors: J.David Spence, Louise Pilote Tags: Invited commentary Source Type: research

Race and Ethnicity, Obesity, Metabolic Health, and Risk of Cardiovascular Disease in Postmenopausal Women Epidemiology
Conclusions Metabolic abnormalities appeared to convey more cardiovascular risk among black women.
Source: JAHA:Journal of the American Heart Association - May 20, 2015 Category: Cardiology Authors: Schmiegelow, M. D., Hedlin, H., Mackey, R. H., Martin, L. W., Vitolins, M. Z., Stefanick, M. L., Perez, M. V., Allison, M., Hlatky, M. A. Tags: Epidemiology Source Type: research

The metabolic syndrome in hypertensive black population of South Algeria.
CONCLUSION: The MS is highly prevailing among hypertensive black population, and significantly higher among women. The ranking of the cluster elements frequency shows clearly the specifities of our population. It is necessary to elaborate an adequate strategy to prevent such cardiovascular morbidity and mortality. PMID: 26044305 [PubMed - as supplied by publisher]
Source: Annales de Cardiologie et d'Angeiologie - June 1, 2015 Category: Cardiology Authors: Bachir Cherif A, Temmar M, Chibane A, Labat C, Atif ML, Taleb A, Benetos A, Bouafia MT Tags: Ann Cardiol Angeiol (Paris) Source Type: research

Erectile dysfunction and coronary heart disease
Purpose of review: This narrative review discusses the associations of erectile dysfunction with coronary heart disease (CHD) morbidity and mortality, all-cause death and CHD risk factors. Treatment strategies for erectile dysfunction are also mentioned. Recent findings: Erectile dysfunction shares common pathways and risk factors with vascular diseases. Erectile dysfunction has been reported to independently predict CHD events, thus highlighting its role as a marker of early atherosclerosis. Erectile dysfunction prevalence may be followed by the presentation of CHD symptoms in 2–3 years, and a CHD event may occur in 3â€...
Source: Current Opinion in Cardiology - June 8, 2015 Category: Cardiology Tags: LIPIDS AND EMERGING RISK FACTORS: Edited by Dimitri P. Mikhailidis and Anthony S. Wierzbicki Source Type: research

Metabolic Syndrome and Cardiovascular Risk in Elderly Treated Hypertensive Patients.
CONCLUSIONS: In elderly treated hypertensive patients, MetS is associated with increased cardiovascular risk, but not independently of BP and glucose levels and of organ damage. PMID: 26224400 [PubMed - as supplied by publisher]
Source: American Journal of Hypertension - July 29, 2015 Category: Cardiology Authors: Pierdomenico SD, Pierdomenico AM, Di Tommaso R, Coccina F, Di Carlo S, Cuccurullo F, Porreca E Tags: Am J Hypertens Source Type: research

Testosterone replacement and cardiovascular disease risk: what do endocrinologists need to know?
Testosterone deficiency (or hypogonadism) affects millions of men worldwide. Consensus regarding an appropriate biochemical cutoff for the definition and treatment of hypogonadism has been challenging. Several recent, well-publicized studies have called into question the long recognized benefits of testosterone replacement therapy. The aim of the current article is to review the data on testosterone treatment, paying specific attention to the potential cardiovascular effects of this increasingly common therapy. We examine some of the most common cardiovascular diseases including hypertension, metabolic syndrome, coronary a...
Source: Cardiovascular Endocrinology - August 14, 2015 Category: Cardiology Tags: Invited reviews Source Type: research

Role of the Renin-Angiotensin-Aldosterone System and Its Pharmacological Inhibitors in Cardiovascular Diseases: Complex and Critical Issues
Abstract Hypertension is one of the major risk factor able to promote development and progression of several cardiovascular diseases, including left ventricular hypertrophy and dysfunction, myocardial infarction, stroke, and congestive heart failure. Also, it is one of the major driven of high cardiovascular risk profile in patients with metabolic complications, including obesity, metabolic syndrome and diabetes, as well as in those with renal disease. Thus, effective control of hypertension is a key factor for any preventing strategy aimed at reducing the burden of hypertension-related cardiovascular diseases in ...
Source: High Blood Pressure and Cardiovascular Prevention - September 24, 2015 Category: Cardiology Source Type: research

Insulin resistance: an additional risk factor in the pathogenesis of cardiovascular disease in type 2 diabetes
Abstract Sedentary life style and high calorie dietary habits are prominent leading cause of metabolic syndrome in modern world. Obesity plays a central role in occurrence of various diseases like hyperinsulinemia, hyperglycemia and hyperlipidemia, which lead to insulin resistance and metabolic derangements like cardiovascular diseases (CVDs) mediated by oxidative stress. The mortality rate due to CVDs is on the rise in developing countries. Insulin resistance (IR) leads to micro or macro angiopathy, peripheral arterial dysfunction, hampered blood flow, hypertension, as well as the cardiomyocyte and the endothelia...
Source: Heart Failure Reviews - November 5, 2015 Category: Cardiology Source Type: research