Ventricular fibrillation associated with Graves' disease and amiodarone induced thyrotoxicosis
This case involves a 55-year-old male patient with systolic heart failure and refractory atrial fibrillation due to thyrotoxicosis, who was electrically cardioverted but then developed torsade de pointes and ventricular fibrillation. Rate control was unsuccessful with digoxin, cardizem, labetalol, esmolol and amiodorone. Patient was externally cardioverted after which ECGs showed prolonged QT with frequent premature ventricular contractions. ECGs also showed ‘R-on-T' phenomenon leading to torsades and ventricular fibrillation. Atrial overdrive pacing was used to terminate the dangerous arrhythmia and the patient retu...
Source: Cardiovascular Endocrinology - November 8, 2019 Category: Cardiology Tags: Case Report Source Type: research

Left ventricular mass index and subendocardial myocardial function in children with chronic kidney disease, a transmural strain and three-dimensional echocardiographic study
This study has been conducted on 40 CKD patients (Group 1) and 40 age-matched controls, both groups were assessed by transmural echocardiography to determine the subepicardial and subendocardial global longitudinal strain (GLS) as an expression of the systolic function of each of those layers. LVH was assessed by calculation of left ventricle mass index (LVMI). Both groups underwent ambulatory blood pressure monitoring. Group 1 was assessed as regards lipid profile and insulin resistance by homeostasis model assessment of insulin resistance (HOMA-IR). Results HOMA-IR proved to be a more important determinant of LV hyper...
Source: Cardiovascular Endocrinology - November 8, 2019 Category: Cardiology Tags: Original Articles Source Type: research

The comparison of the relationships about the presence of branch retinal vein occlusion and endothelial functions between diabetic and non-diabetic patients
Objectives The aim of this study was to investigate the endothelial functions in both patients with diabetics and non-diabetics with branch retinal vein occlusion by using pulse wave analysis and flow-mediated dilatation methods. Patients and methods This cross-sectional study included a total of 136 participants (47 diabetic patients with branch retinal vein occlusion, 43 non-diabetic patients with branch retinal vein occlusion, and 46 otherwise healthy subjects). Evaluation of endothelial functions was performed by flow-mediated dilatation and pulse wave analysis methods. Stiffness index, reflection index (RI), and ...
Source: Cardiovascular Endocrinology - November 8, 2019 Category: Cardiology Tags: Original Articles Source Type: research

Estimation of apolipoprotein A in early onset ST-segment elevation myocardial infarction
This study sought to assess the apolipoprotein A in cohort of patients diagnosed with early onset acute ST-segment elevation myocardial infarction and to corelate it with major traditional cardiovascular risk factors. Methods A total of 50 such patients and 40 age and sex-matched healthy controls, both aged less than 50 years with their baseline demographic, clinical characteristics and cardiovascular risk factors were studied. Apolipoprotein A was estimated for all enrollees. Results The mean age of cases was 43.37 ± 5.85 years. The levels of apolipoprotein A among cases were not significantly lower compared ...
Source: Cardiovascular Endocrinology - November 8, 2019 Category: Cardiology Tags: Original Articles Source Type: research

Cardioprotective diabetes drugs: what cardiologists need to know
In patients with diabetes, where cardiovascular morbidity is highly prevalent, recent cardiovascular outcomes trials have identified therapies in the modern glucagon-like peptide 1 receptor agonist (GLP-1RA) and sodium-glucose cotransporter 2 inhibitor (SGLT2i) classes that significantly reduce cardiovascular events. A number of drugs in both classes have demonstrated reductions in the risk of the composite outcome of major adverse cardiovascular events (myocardial infarction, stroke, and cardiovascular death). In addition, SGLT2i drugs have a substantial impact on hospitalization for heart failure. Because GLP-1RA and SGL...
Source: Cardiovascular Endocrinology - November 8, 2019 Category: Cardiology Tags: Review Articles Source Type: research

Further insights into cardiovascular outcomes in diabetic and non-diabetic states: inhibition of sodium-glucose co-transports
Cardiovascular diseases are the leading cause of morbidity and mortality in the world. Diabetes increase heart disease related to death by two- to four-fold. SGLT2 inhibitors are new antidiabetic agents. The growing evidence of cardiovascular benefit of SGLT2 inhibitors independent of their effects on glycemic control is especially intriguing. Several clinical trials have shown that sotagliflozin (SGLT1-1/2 inhibitor) decreases body weight and reduces blood pressure in adults with T2D. A phase 3 study designed to evaluate cardiovascular outcomes of sotagliflozin is currently ongoing. Many pre-clinical studies were conducte...
Source: Cardiovascular Endocrinology - November 8, 2019 Category: Cardiology Tags: Review Articles Source Type: research

27th Annual Meeting of the European Group for the study of Insulin Resistance, Lisbon, Portugal, 8–9th May 2019
No abstract available (Source: Cardiovascular Endocrinology)
Source: Cardiovascular Endocrinology - September 1, 2019 Category: Cardiology Tags: Short Report Source Type: research

Association of neutrophil-gelatinase-associated lipocalin with microvascular complications in patients with type 2 diabetes: a cross-sectional study
Conclusion There are controversial findings about the role of NGAL in diabetic patients in medical literature. Standard values of urine and serum NGAL levels have yet to be determined. Our study suggests that NGAL is not a useful marker to differentiate microalbuminuric patients from normoalbuminuric subjects. We also did not find a relationship between NGAL levels and the presence of retinopathy. Additional studies with larger sample sizes will be required to confirm or refute these findings. (Source: Cardiovascular Endocrinology)
Source: Cardiovascular Endocrinology - September 1, 2019 Category: Cardiology Tags: Original Articles Source Type: research

Relative fat mass is a better predictor of dyslipidemia and metabolic syndrome than body mass index
Background Relative fat mass (RFM) had been recently developed. We aimed to examine RFM predictability to various cardiometabolic risk factors, compared to BMI. Methods Observational, cohort study, among patients who visited the Rambam Periodic Examinations Institute (RPEI). We compared the correlation of BMI and RFM to hypertension, impaired fasting glucose, high LDL, low HDL and metabolic syndrome, by gender. Results During study years, 20 167 patients visited the RPEI and included in the trial. Compared to BMI, RFM showed significantly better predictability (odds ratio [OR], [95% confidence interval (CI), P valu...
Source: Cardiovascular Endocrinology - September 1, 2019 Category: Cardiology Tags: Original Articles Source Type: research

Association of lipid peroxidation and interleukin-6 with carotid atherosclerosis in type 2 diabetes
Aim Enhanced lipid peroxidation and elevated interleukin-6 levels are common in type 2 diabetes mellitus patients. Atherosclerotic vascular complications greatly contribute to morbidity and mortality in diabetes. The aim of this study was to assess the relation of lipid peroxidation and interleukin-6 with carotid atherosclerosis in type 2 diabetes mellitus. Methods This cross-sectional study included 90 type 2 diabetes mellitus male patients with age ≥ 40 years and 30 healthy male subjects matched for age. All of them were subjected to measuring of 8-iso prostaglandin F2α as a marker of lipid peroxidation, in...
Source: Cardiovascular Endocrinology - September 1, 2019 Category: Cardiology Tags: Original Articles Source Type: research

Addressing the impact of type 2 diabetes in ageing populations: the launch of the 2019 Endocrine Society Task Force Guideline
No abstract available (Source: Cardiovascular Endocrinology)
Source: Cardiovascular Endocrinology - September 1, 2019 Category: Cardiology Tags: Commentary Source Type: research

Elizabeth Barrett-Connor (1935–2019): an appreciation
No abstract available (Source: Cardiovascular Endocrinology)
Source: Cardiovascular Endocrinology - September 1, 2019 Category: Cardiology Tags: Appreciation Source Type: research

DiRECT and indirect paths to reducing cardiovascular risk in diabetes: insights from Diabetes UK 2019
No abstract available (Source: Cardiovascular Endocrinology)
Source: Cardiovascular Endocrinology - May 2, 2019 Category: Cardiology Tags: Short Report Source Type: research

Correlation between the serum procalcitonin level and the extension and severity of coronary artery disease in patients with non-ST-segment elevation myocardial infarction
Conclusion The second 24-h postadmission serum PCT level was not correlated with the severity and extension of CAD according to the Gensini score in our patients with NSTEMI. (Source: Cardiovascular Endocrinology)
Source: Cardiovascular Endocrinology - May 2, 2019 Category: Cardiology Tags: Original Article Source Type: research

Atherosclerosis: integration of its pathogenesis as a self-perpetuating propagating inflammation: a review
This review proposes that the development of the atherosclerotic plaque is critically dependent on its inflammatory components forming a self-perpetuating and propagating positive feedback loop. The components involved are: (1) LDL oxidation, (2) activation of the endothelium, (3) recruitment of inflammatory monocytes, (4) macrophage accumulation, which induces LDL oxidation, and (5) macrophage generation of inflammatory mediators, which also activate the endothelium. Through these stages, the positive feedback loop is formed, which generates and promotes expansion of the atherosclerotic process. To illustrate this dynamic...
Source: Cardiovascular Endocrinology - May 2, 2019 Category: Cardiology Tags: Review Source Type: research

Vascular disease and type 2 diabetes: the science policy case for early cardiometabolic intervention
No abstract available (Source: Cardiovascular Endocrinology)
Source: Cardiovascular Endocrinology - May 2, 2019 Category: Cardiology Tags: Editorials Source Type: research

Cardiometabolic medicine: time to recognize a new clinical specialty?
No abstract available (Source: Cardiovascular Endocrinology)
Source: Cardiovascular Endocrinology - May 2, 2019 Category: Cardiology Tags: Editorials Source Type: research

Vascular disease in the lower limb in type 1 diabetes
This review considers peripheral arterial disease (PAD) in the diabetic ischaemic lower limb including both macrovascular and microvascular aspects. The presentation of PAD is probably not significantly different in type 1 compared with type 2 diabetes. PAD in diabetic patients is diffuse and located distally being most severe in the crural and also the foot arteries. It is associated with arterial calcification and occlusion of the arteries rather than stenosis. Compared with the nondiabetic patient, PAD develops at a younger age, and women are equally affected as men. It is not known whether the presentation of ischaemic...
Source: Cardiovascular Endocrinology - March 1, 2019 Category: Cardiology Tags: Review articles Source Type: research

Type 1 diabetes mellitus and coronary revascularization
Over the last three decades, trials of coronary revascularization have taken into account whether populations did or did not have diabetes. What has not been considered is whether or not patients with diabetes in these studies have type 1 or type 2 diabetes. ‘Diabetes’ appears to be largely used as a synonym for type 2 diabetes. The number of patients with type 1 diabetes has not been reported in most trials. Many questions remain unanswered. Do patients with type 1 diabetes have the same response to various modes of revascularization as those with type 2 diabetes? We know type 2 diabetes affects coronary endot...
Source: Cardiovascular Endocrinology - March 1, 2019 Category: Cardiology Tags: Review articles Source Type: research

Cardiovascular disease in type 1 diabetes
Cardiovascular disease (CVD) is a well-recognized complication of diabetes. Although the association of type 2 diabetes with CVD has been well described, the mechanisms, risk stratification and screening strategies of CVD in type 1 diabetes (T1D) are less understood. This review aims to evaluate recent literature and guidelines regarding CVD in T1D. At the cellular level, the early stage of CVD is characterized by endothelial dysfunction. Recent studies have shown that endothelial function is unaffected in younger T1D patients but there is a significant degree of endothelial dysfunction in the older T1D population compared...
Source: Cardiovascular Endocrinology - March 1, 2019 Category: Cardiology Tags: Review articles Source Type: research

The early detection of atherosclerosis in type 1 diabetes: why, how and what to do about it
The major cause of morbidity and often premature mortality in people with type I diabetes (T1D) is cardiovascular disease owing to accelerated atherosclerosis. We review publications relating to the rationale behind, and clinical tests for, detecting and treating early atherosclerosis in people with T1D. Currently available tools for atherosclerosis assessment include risk equations using vascular risk factors, arterial intima–media thickness, the ankle–brachial index, coronary artery calcification and angiography, and for more advanced lesions, intravascular ultrasound and optical coherence tomography. Evolvin...
Source: Cardiovascular Endocrinology - March 1, 2019 Category: Cardiology Tags: Review articles Source Type: research

Recent trends over time in vascular disease in type 1 diabetes: insights from the Pittsburgh Epidemiology of Diabetes Complications study
Conclusion Despite declines in all-cause, cardiovascular and renal mortality in the total cohort, no improvements were observed in either mortality or complication incidence with a more recent onset in the examined cohort. (Source: Cardiovascular Endocrinology)
Source: Cardiovascular Endocrinology - March 1, 2019 Category: Cardiology Tags: Review articles Source Type: research

Cardiovascular disease in type 1 diabetes: the elephant in the clinic
No abstract available (Source: Cardiovascular Endocrinology)
Source: Cardiovascular Endocrinology - March 1, 2019 Category: Cardiology Tags: Editorial Source Type: research

Abstracts
No abstract available (Source: Cardiovascular Endocrinology)
Source: Cardiovascular Endocrinology - November 7, 2018 Category: Cardiology Tags: Abstracts: PDF Only Source Type: research

Association between thyroid abnormalities and hypertension among hospitalized US patients: data from the National Inpatient Sample
Abnormalities of thyroid, namely hyperthyroidism and hypothyroidism, are both associated with increased risk of hypertension. We utilized the National Inpatient Sample from the years 2012–2014 to explore the risk of thyroid disorders in relation to those without a thyroid diagnosis. We found that hypertension was more commonly associated with hyperthyroidism (odds ratio: 1.18; 95% confidence interval: 1.16–1.21, P (Source: Cardiovascular Endocrinology)
Source: Cardiovascular Endocrinology - November 7, 2018 Category: Cardiology Tags: Short report Source Type: research

Vitamin D status in acute myocardial infarction: a case–control study
This study seeks the association between vitamin D deficiency and acute myocardial infarction (MI) in Iraq. Patients and methods A total of 104 patients with acute MI and 104 healthy controls were studied throughout 2015. Their demographic, cardiovascular risk factors, and clinical characteristics were recorded. Serum vitamin D measurement was carried out for all patients. Results Vitamin D was more deficient in cases than controls; the number of cases was 60 (57.7%) and 53 (51%), respectively. However, a statistically significant difference (P=0.6) was not obtained. In the patient group, type 2 diabetes mellitus sho...
Source: Cardiovascular Endocrinology - November 7, 2018 Category: Cardiology Tags: Original articles Source Type: research

Association between asymmetric dimethylarginine serum levels and left ventricular longitudinal deformation in patients with normal ejection fractions: a two-dimensional speckle-tracking echocardiography examination
Conclusion Our findings showed no statistically significant correlations between the serum ADMA level and the 2DSTE-derived indices of the longitudinal deformation of the LV myocardium in our nondiabetic patients without significant coronary artery stenosis and with normal LV ejection fractions. (Source: Cardiovascular Endocrinology)
Source: Cardiovascular Endocrinology - November 7, 2018 Category: Cardiology Tags: Original articles Source Type: research

Serum leptin in male hypothyroid prediabetic patients: Association with cardiovascular risk
Conclusion Hypothyroidism is associated with high serum leptin independent of prediabetic state. Serum leptin in hypothyroid prediabetic patients showed a direct relationship with some primary markers of metabolic syndrome; thus, leptin may predict the development of CHD in those patients. (Source: Cardiovascular Endocrinology)
Source: Cardiovascular Endocrinology - November 7, 2018 Category: Cardiology Tags: Original articles Source Type: research

Development of clinical trials to extend healthy lifespan
We describe the rationale and collaborative, consensus building approach used to design the first aging outcome trial called Targeting Aging with Metformin. Through this case study, we outline features that could be more broadly extended to other geroscience-guided clinical trials, including a process for selecting biochemical and molecular markers of biologic age and we provide a perspective on the potential impact of clinical trials targeting aging. (Source: Cardiovascular Endocrinology)
Source: Cardiovascular Endocrinology - November 7, 2018 Category: Cardiology Tags: Review articles Source Type: research

In-vivo metabolic studies of regional adipose tissue
The accumulation of abdominal adipose tissue has long been associated with adverse cardiovascular outcomes. Paradoxically, increased gluteofemoral adipose tissue, which is predominantly subcutaneous fat, seems to play a protective role. There has been significant scientific interest in understanding how abdominal and gluteofemoral depots confer opposing metabolic risks. However, the study of regional adipose physiology in vivo remains challenging. We discuss some of the methodologies used. We focus specifically on the arteriovenous difference technique and present some insights into gluteofemoral adipose physiology. (Sourc...
Source: Cardiovascular Endocrinology - November 7, 2018 Category: Cardiology Tags: Review articles Source Type: research

26th Annual Meeting of the European Group for the study of Insulin Resistance, Lille, France, 7–8th June 2018
No abstract available (Source: Cardiovascular Endocrinology)
Source: Cardiovascular Endocrinology - November 7, 2018 Category: Cardiology Tags: Editorials Source Type: research

Diabetes: learning from the past 25 years and looking to the future
No abstract available (Source: Cardiovascular Endocrinology)
Source: Cardiovascular Endocrinology - November 7, 2018 Category: Cardiology Tags: Editorials Source Type: research

Type 2 diabetes and susceptibility to atrial fibrillation: the two facets of downregulation of MiR-126?
No abstract available (Source: Cardiovascular Endocrinology)
Source: Cardiovascular Endocrinology - August 12, 2018 Category: Cardiology Tags: Correspondence Source Type: research

Is diabetes mellitus equivalent to atherosclerotic cardiovascular disease from a healthcare cost perspective? Insights from the Medical Expenditure Panel Survey: 2010–2013
Diabetes mellitus (DM) and atherosclerotic cardiovascular disease (ASCVD) both increase the risk for a major adverse cardiac event, and are therefore considered priority conditions clinically. Although guidelines encourage clinicians to treat them similarly, many researchers do not consider DM an ASCVD risk-equivalent. However, from a healthcare system standpoint it is more important to determine whether DM is an economic burden equivalent to ASCVD. Using data from the Household Component of the 2010–2013 Medical Expenditure Panel Survey, we determined that the diagnosis of DM yields significantly lower healthcare ex...
Source: Cardiovascular Endocrinology - August 12, 2018 Category: Cardiology Tags: Short Report Source Type: research

Interaction between cardiovascular autonomic control and sex hormones in perimenopausal women under menopausal hormone therapy
Conclusion The obtained results may indicate the independence of heart autonomic control (assessed by HRV measures) from women’s hormonal status. However, any changes in sex hormones contribute to changes in the systemic control of circulation, which is assessed by index S. (Source: Cardiovascular Endocrinology)
Source: Cardiovascular Endocrinology - August 12, 2018 Category: Cardiology Tags: Original Article Source Type: research

Milk and dairy foods: implications for cardiometabolic health
No abstract available (Source: Cardiovascular Endocrinology)
Source: Cardiovascular Endocrinology - August 12, 2018 Category: Cardiology Tags: Editorial Source Type: research

Leveling-off of declining trend of cardiovascular disease-related mortality in the USA: the challenge to rein in obesity and diabetes epidemic
No abstract available (Source: Cardiovascular Endocrinology)
Source: Cardiovascular Endocrinology - May 10, 2018 Category: Cardiology Tags: Viewpoint Source Type: research

Glycemic variability is associated with myocardial damage in nondiabetic patients with ST-elevation myocardial infarction
Background Glycemic variability (GV) induces coronary microcirculatory disturbance and myocardial damage in diabetic patients with acute myocardial infarction. However, in nondiabetic acute myocardial infarction patients, the relationship between GV and myocardial damage remains unclear. Patients and methods We investigated GV with a continuous glucose monitoring system in nondiabetic ST-segment elevation myocardial infarction patients treated with emergent percutaneous coronary intervention. GV was expressed as the mean amplitude of glycemic excursions (MAGE). Myocardial damage was estimated by myocardial blush grade...
Source: Cardiovascular Endocrinology - May 10, 2018 Category: Cardiology Tags: Original articles Source Type: research

The relationship between serum endocan levels and the presence/severity of isolated coronary artery ectasia
Conclusion Plasma endocan levels may reflect the presence of isolated CAE, suggesting that endocan may be involved in the pathogenesis of isolated CAE. (Source: Cardiovascular Endocrinology)
Source: Cardiovascular Endocrinology - May 10, 2018 Category: Cardiology Tags: Original articles Source Type: research

Advances in the relationship between Kruppel-like factor 15 and cardiovascular disease research
Kruppel-like factor 15 (KLF15) is a subtype of the Kruppel-like family of transcription factors (KLFs). KLFs have three high-fidelity zinc fingers at the carboxyl terminus that enable them to regulate the biological processes of proliferation, differentiation, cellular development, and apoptosis. KLF15 is highly expressed in the kidney, pancreas, and cardiac and skeletal muscle, and plays an essential role in the development and occurrence of multiple system diseases. In this paper, we underscored the important relationship between KLF15 and cardiovascular diseases such as atherosclerosis, heart failure, arrhythmia, aortic...
Source: Cardiovascular Endocrinology - May 10, 2018 Category: Cardiology Tags: Review article Source Type: research

Diagnostic challenges in supraventricular tachycardia: anticipating value of natriuretic peptides
It is important not to overlook supraventricular tachycardia (SVT) in patients complaining of palpitation or tachycardia-related symptoms but with normal ECG and heart rate in emergency department or outpatient clinics. The severity and presentation of symptoms is highly variable and depends on features including heart rate, duration of tachycardia, underlying heart disease, and individual patient perception. Early measurement of natriuretic peptides in patients presenting with palpitation and/or tachycardia-related symptoms would guide the clinician to rule out tachycardia and/or SVT. High levels of natriuretic peptides w...
Source: Cardiovascular Endocrinology - May 10, 2018 Category: Cardiology Tags: Short report Source Type: research

The role of OPG/RANKL in the pathogenesis of diabetic cardiovascular disease
Cardiovascular (CV) disease is the leading cause of mortality in patients with type 2 diabetes mellitus. A major factor in the pathogenesis of CV disease is vascular calcification (VC), which is accelerated in type 2 diabetes mellitus. Calcification of the vessel wall contributes to vascular stiffness and left ventricular hypertrophy whereas intimal calcification may predispose to plaque rupture and CV death. The pathogenesis of VC is complex but appears to be regulated by the osteoprotegerin (OPG)/receptor activator of nuclear factor-κB ligand (RANKL) signaling pathway, which is involved in bone remodeling. Within t...
Source: Cardiovascular Endocrinology - May 10, 2018 Category: Cardiology Tags: Review article Source Type: research

Integrating cardioprotective glucose-lowering medications into clinical practice
Patients with type 2 diabetes suffer from both microvascular and macrovascular complications. Optimal glycemic control is well known to reduce the microvascular complications of retinopathy, nephropathy, and neuropathy. However, despite having multiple classes of antidiabetes medications, we have not been able to favorably affect the cardiovascular (CV) complications of diabetes, which cause considerable morbidity and premature CV mortality in patients with diabetes. The recent publication of the EMPA-REG Outcome and the LEADER studies demonstrating favorable CV outcomes with empagliflozin and liraglutide have led to a dec...
Source: Cardiovascular Endocrinology - February 19, 2018 Category: Cardiology Tags: Review articles Source Type: research

Mechanism of cardiovascular disease benefit of glucagon-like peptide 1 agonists
Glucagon-like peptide 1 (GLP-1)-based therapies reduce hyperglycaemia in type 2 diabetes. Diabetes cardiovascular comorbidity remains prevalent, although current treatments are effective at reducing hyperglycaemia. GLP-1 exerts specific actions on the cardiovascular system in both healthy individuals and patients with cardiovascular pathology, and GLP-1 therapies have improved the cardiovascular profile of diabetic patients. GLP-1 exerts its action by binding to its receptor (GLP-1 receptor) at the cell surface. Mechanistically, it is not clear how GLP-1 therapies exert beneficial effects on the cardiovascular system. It i...
Source: Cardiovascular Endocrinology - February 19, 2018 Category: Cardiology Tags: Review articles Source Type: research

The impact of glucose-lowering medications on cardiovascular disease
Patients with type 2 diabetes mellitus die most frequently from cardiovascular disease. Metabolic control is mandatory both for preventing long-term complications and for reducing the negative effects of the exposure of the other risk factors. In this article, we will describe the most commonly used glucose-lowering agents, the pathophysiological mechanisms underlying their cardiovascular protection, the available evidence-based data for this protection, and the contraindications and potential adverse effects. (Source: Cardiovascular Endocrinology)
Source: Cardiovascular Endocrinology - February 19, 2018 Category: Cardiology Tags: Review articles Source Type: research

Heart failure: an underestimated therapeutic target in diabetes
Heart failure (HF) is a frequent finding in patients with diabetes and is associated with an impaired prognosis with respect to the need for hospitalization as well as mortality. The following article presents an overview of the incidence and prognosis of HF in patients with type 2 diabetes and discusses the effects of various antidiabetic drugs on HF. (Source: Cardiovascular Endocrinology)
Source: Cardiovascular Endocrinology - February 19, 2018 Category: Cardiology Tags: Review articles Source Type: research

Pathophysiology of cardiovascular disease in diabetes mellitus
Diabetes mellitus elicits cellular, epigenetic, and post-translational changes that directly or indirectly affect the biology of the vasculature and other metabolic systems resulting in the apparition of cardiovascular disease. In this review, we provide a current perspective on the most recent discoveries in this field, with particular focus on hyperglycemia- induced pathology in the cardiovascular system. We also provide perspective on the clinical importance of molecular targeting of cardiovascular and diabetes mellitus therapies to treat hyperglycemia, inflammation, thrombosis, dyslipidemia, atherosclerosis, and hypert...
Source: Cardiovascular Endocrinology - February 19, 2018 Category: Cardiology Tags: Review articles Source Type: research

Cardioprotective glucose-lowering medications: evidence and uncertainties in a new therapeutic era
No abstract available (Source: Cardiovascular Endocrinology)
Source: Cardiovascular Endocrinology - February 19, 2018 Category: Cardiology Tags: Editorials Source Type: research

Cardiovascular Endocrinology & Metabolism
No abstract available (Source: Cardiovascular Endocrinology)
Source: Cardiovascular Endocrinology - February 19, 2018 Category: Cardiology Tags: Editorials Source Type: research

Oxford Diabetes Symposium 2017
No abstract available (Source: Cardiovascular Endocrinology)
Source: Cardiovascular Endocrinology - December 1, 2017 Category: Cardiology Tags: Short report Source Type: research