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Is stroke incidence increased in survivors of adult cancers? A systematic review and meta-analysis
ConclusionsStroke incidence is significantly increased after diagnosis of certain cancers.Implications for Cancer SurvivorsCardiovascular risk should be assessed during cancer survivorship care, with attention to modifying shared cancer/cardiovascular risk factors.
Source: Journal of Cancer Survivorship - November 5, 2021 Category: Cancer & Oncology Source Type: research

Cancers, Vol. 13, Pages 2193: Prognosis of Acute Ischaemic Stroke Patients with Cancer: A National Inpatient Sample Study
K Myint Whilst cancer is a risk factor for acute ischaemic stroke (AIS), its impact on AIS prognosis between metastatic and non-metastatic (MC and NMC) disease is poorly understood. Furthermore, the receipt of intravenous thrombolysis (IVT) and endovascular thrombectomy (ET) and their outcomes is poorly researched. AIS admissions from the National Inpatient Sample (NIS) were included (October 2015–December 2017). Multivariable logistic regressions adjusting for a wide range of confounders analysed the relationship between NMC and MC and AIS in-hospital outcomes (mortality, prolonged hospitalisation >4 days...
Source: Cancers - May 3, 2021 Category: Cancer & Oncology Authors: Tiberiu A Pana Mohamed O Mohamed Mamas A Mamas Phyo K Myint Tags: Article Source Type: research

Recurrent Strokes as the First Presentation of Occult Pancreatic Cancer; Trousseau Syndrome: A Case Report
We present a case of a 64-year-old female with recurrent ischemic stroke of unknown cause and involving different arterial territories, who was discovered to have metastatic pancreatic cancer. The initial workup with brain imaging revealed multiple acute/subacute ischemic strokes and a negative cardiac assessment. Accordingly, she underwent a whole-body positron emission tomography-computed tomography which revealed a hypermetabolic mass lesion in the pancreaticoduodenal area. Our case indicates that cancer-associated stroke should be seriously evaluated. It demonstrates the critical nature of contemplating hidden cancer i...
Source: Case Reports in Oncology - December 10, 2021 Category: Cancer & Oncology Source Type: research

Abstract A12: Cancer communication in African American churches
Conclusion: Cancer was a frequent topic for disease-focused messages in African-American churches. In addition, three of the five most frequent disease topics matched the leading causes of death in the African-American community. The match was not as close in regards to leading causes of cancer death. Breast and prostate cancer information was frequently found; however, despite the high rates of mortality associated with lung cancer, colorectal cancer, and leukemia/lymphoma, information on these cancers was present much less frequently. No pancreatic cancer messages were found. Disease related information was seen that inc...
Source: Cancer Epidemiology Biomarkers and Prevention - November 13, 2014 Category: Cancer & Oncology Authors: Harmon, B. E., Chastain, E., Chock, M., Wirth, M., Hebert, J. R. Tags: Cancer Communications: Poster Presentations - Proffered Abstracts Source Type: research

Pulmonary Embolism and Stroke as the Initial Manifestation of Advanced Metastatic Pancreatic Adenocarcinoma
Source: International Journal of Gastrointestinal Cancer - March 5, 2015 Category: Cancer & Oncology Source Type: research

A phase I study of cetuximab in combination with gemcitabine and radiation for locally advanced pancreatic cancer.
CONCLUSIONS: The combination of cetuximab, gemcitabine, and radiation resulted in significant toxicity. A recommended phase II dose could not be determined. PMID: 23077684 [PubMed]
Source: Gastrointestinal Cancer Research - June 4, 2015 Category: Cancer & Oncology Tags: Gastrointest Cancer Res Source Type: research

NAMPT as a Dedifferentiation-Inducer Gene: NAD+ as Core Axis for Glioma Cancer Stem-Like Cells Maintenance
Conclusion and Perspectives Gliomas are the most prevalent primary brain cancer in adults and include a broad category of tumors including astrocytoma, oligodendroglioma, and GBM. Regardless of tumor aggressiveness, malignancy, and infiltration, these glia-derived tumors rarely exceed a median survival time of 12–14 months. Driven by the infiltrative nature of these tumors, the clinical approach is difficult and relapses often occur with fatal consequences. These unsuccessful attempts to control glioma's fate have fostered research looking for more effective therapies. (GSCs) are a small subset of CD133&#...
Source: Frontiers in Oncology - May 2, 2019 Category: Cancer & Oncology Source Type: research

Incidence and Risk of Various Types of Arterial Thromboembolism in Patients With Cancer
CONCLUSION: In this observational study of an aggregated US patient population, those with newly diagnosed cancer had increased risk of ATE events. This risk was most elevated in a 330-day window around cancer diagnosis and was consistent across different types of ATE and cancer.PMID:33673912 | DOI:10.1016/j.mayocp.2020.05.045
Source: Clinical Colorectal Cancer - March 6, 2021 Category: Cancer & Oncology Authors: Jiasheng Wang Yeseong D Kim Chang H Kim Source Type: research

Anticoagulation for atrial fibrillation in active cancer
Oncol Lett. 2022 Apr;23(4):124. doi: 10.3892/ol.2022.13244. Epub 2022 Feb 17.ABSTRACTAtrial fibrillation (AF) may often pre-exist in patients with newly diagnosed cancer or occur with increased frequency shortly after cancer diagnosis. Patients with active cancer and AF have a particularly high risk of thromboembolic complications, as both conditions carry a risk of thrombosis. Thromboembolic risk is determined by several factors, including advanced age, sex (females), cancer histology (adenocarcinomas), location (e.g., pancreas, stomach), advanced stage, anticancer regimens (e.g., platinum compounds, anti-angiogenic thera...
Source: Oncology Letters - March 9, 2022 Category: Cancer & Oncology Authors: Dimitrios Farmakis Pavlos Papakotoulas Eleni Angelopoulou Theodoros Bischiniotis George Giannakoulas Panagiotis Kliridis Dimitrios Richter Ioannis Paraskevaidis Source Type: research

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