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Cancer: Head and Neck Cancer
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Total 69 results found since Jan 2013.

Dementia Risk in Irradiated Patients With Head and Neck Cancer
This study estimated the dementia risk associated with different treatment modalities in a head and neck cancer population with long-term follow-up. Taiwan's National Health Insurance claims database and a cancer registry database from the Collaboration Center of Health Information Application were linked for the present analysis. Patients with head and neck cancer, treated from January 1, 2002 to December 31, 2010, were included in the study. The follow-up duration was the period from the index date to December 31, 2012. Inclusion criteria were head and neck cancer; an age>20 years; and having undergone surgery, CT, concu...
Source: Medicine - November 1, 2015 Category: Internal Medicine Tags: Research Article: Observational Study Source Type: research

$10 million gift to UCLA from Wendy and Leonard Goldberg is largest ever to support migraine research
UCLA Health Sciences has received a $10 million gift, most of which will support multidisciplinary research on migraine, a debilitating neurological disorder that affects 36 million people in the U.S. The gift was made by philanthropists Wendy and Leonard Goldberg. Wendy Goldberg is an editor and author; her husband, Leonard, is an award-winning film and television producer and executive. More than 90 percent of sufferers are unable to work during their migraine attacks, costing employers $13 billion a year in lost work days; and every 10 seconds, someone in the U.S. goes to an emergency room with a migraine-related compla...
Source: UCLA Newsroom: Health Sciences - December 8, 2015 Category: Universities & Medical Training Source Type: news

Development of the Brief Bedside Dysphagia Screening Test - Revised: a Cross-Sectional Czech Study.
CONCLUSION: The BBDST-R is suitable for dysphagia screening in departments caring for patients with neurological conditions. PMID: 26455566 [PubMed - in process]
Source: Acta Medica: Hradec Kralove - December 12, 2015 Category: Journals (General) Tags: Acta Medica (Hradec Kralove) Source Type: research

Daily low-dose aspirin may help combat cancer
Conclusion The systematic review looked at 47 studies and attempted to combine the results, looking for evidence of a beneficial effect of low-dose aspirin on risk of death in people already diagnosed with cancer. The few RCTs identified – the best-quality evidence – did not provide conclusive evidence that aspirin improves survival rates. The rest of the studies were observational in nature, so cannot prove that aspirin reduces the risk of death from cancer. The only significant results were for a 24% reduction in risk of death from colon cancer, and a possible 11% reduced risk of death from prostate cancer. However,...
Source: NHS News Feed - April 22, 2016 Category: Consumer Health News Tags: Cancer Medication Source Type: news

Periodontal disease and risk of all cancers among male never smokers: an updated analysis of the Health Professionals Follow-up Study
Conclusions Advanced periodontitis was associated with a 2.5-fold increase in smoking-related cancers among never smokers. Periodontitis may impact cancer risk through system immune dysregulation. Further studies need to examine the immune impact of advanced periodontitis on cancer, especially for cancers known to be caused by smoking.
Source: Annals of Oncology - April 20, 2016 Category: Cancer & Oncology Authors: Michaud, D. S., Kelsey, K. T., Papathanasiou, E., Genco, C. A., Giovannucci, E. Tags: epidemiology Source Type: research

Needs of Internally Displaced Women and Children in Baghdad, Karbala, and Kirkuk, Iraq
Conclusions The vulnerability of this population is great, and the emotional trauma of multiple displacements, kidnapping and deaths from intentional violence is great. While some aid is reaching families, much more is needed. Though Iraq is a middle income country, reaching the IDPs in central Iraq will take much more in international assistance than is currently being received. Unfortunately, at this time of great need, assistance is being cut back throughout the region because of lack of funding.10 The local civil society organizations which have sprung up in many locations to assist IDPs, offer an avenue for targeting ...
Source: PLOS Currents Disasters - June 10, 2016 Category: Global & Universal Authors: Gilbert Burnham Source Type: research

Cardiac comorbidity in head and neck cancer patients and its influence on cancer treatment selection and mortality: a prospective cohort study
AbstractComorbidity assessment and a profound cardiac examination were implemented into pre-treatment diagnostics to analyze their influence on head and neck squamous cell carcinoma (HNSCC) therapy selection and short-term mortality. Comorbidity was measured prospectively in 49 HNSCC patients using standard indices between 2012 and 2013. Cardiac examinations included electrocardiogram, echocardiography, and bicycle ergometry. Most patients had stage IV tumors (61  %), smoked (61 %), and showed alcohol abuse (57 %); 38 patients (78 %) received a multimodal therapy; 65 % had an adult comorbidity evaluation 27 index ≥2...
Source: European Archives of Oto-Rhino-Laryngology - August 4, 2016 Category: ENT & OMF Source Type: research

Portable disposable ultrathin endoscopy tested through percutaneous endoscopic gastrostomy
Conclusions: Our study shows that portable DUE in facilities without endoscopy equipment may be clinically feasible.
Source: Medicine - November 1, 2016 Category: Internal Medicine Tags: Research Article: Clinical Trial/Experimental Study Source Type: research

Free Tissue Transfers for Head and Neck Reconstruction in Patients with End-Stage Renal Disease on Dialysis: Analysis of Outcomes Using the Taiwan National Health Insurance Research Database
Conclusion Despite greater preoperative risk factors, patients with renal failure on hemodialysis do not appear to have a higher rate of free flap failure following head and neck reconstruction. However, other complications can be minimized by optimizing patient's medical condition to succeed with this reconstructive effort. [...] Thieme Medical Publishers 333 Seventh Avenue, New York, NY 10001, USA.Article in Thieme eJournals: Table of contents  |  Abstract  |  Full text
Source: Journal of Reconstructive Microsurgery - June 16, 2017 Category: Surgery Authors: Manrique, Oscar J. Ciudad, Pedro Sharaf, Basel Martinez-Jorge, Jorys Moran, Steven Mardini, Samir Chen, Hung-Chi Bite, Uldis Cheng, Hsu-Tang Tags: Original Article Source Type: research

Radiation-induced carotid artery lesions
ConclusionsRadiation-induced atherosclerosis is a  different and accelerated form of atherosclerosis, which implies a more aggressive disease with a different biologic behavior. The disease is characterized by a high rate of carotid artery stenosis compared to those observed in nonirradiated control group patients. To prevent the risk of stroke , surveillance and imaging with ultrasonography should enable detection of severe stenosis. Endovascular treatment with a carotid angioplasty and stenting has been proposed as an attractive and minimally invasive alternative for some radiation-induced stenoses.
Source: Strahlentherapie und Onkologie - April 20, 2018 Category: Cancer & Oncology Source Type: research

Neurologic manifestations of elderly patients with cancer.
CONCLUSION: Identifying the frequency and correlation of neurologic manifestations in older cancer patients will allow for the implementation of timely multidisciplinary care in an attempt to improve these patients' health-related quality of life. PMID: 29704209 [PubMed - as supplied by publisher]
Source: Aging Clinical and Experimental Research - April 27, 2018 Category: Geriatrics Authors: Cacho-Díaz B, Lorenzana-Mendoza NA, Reyes-Soto G, Ávila-Funes JA, Navarrete-Reyes AP Tags: Aging Clin Exp Res Source Type: research

Saliva-Omics in Plasma Cell Disorders -- Proof of Concept and Potential As a Non-Invasive Tool for Monitoring Disease Burden and MRD Status
This study provides proof of concept that a range of biologically significant proteins of interest can be reliably detected in the saliva of MM and MGUS patients. The observation of differential expression of FABP5 between MGUS and MM identified these as candidate proteins relevant to malignant transformation of MGUS to symptomatic MM. The demonstration of decreased abundance of FABP5 after achieving remission indicates a correlation with tumour burden. This opens the opportunity to explore candidate salivary biomarkers for use in the clinic for disease monitoring and Minimal Residual Disease (MRD) assessment.DisclosuresNo...
Source: Blood - November 21, 2018 Category: Hematology Authors: Tierney, C., Bazou, D., Le, G., Dowling, P., O'Gorman, P. Tags: 651. Myeloma: Biology and Pathophysiology, excluding Therapy: Poster II Source Type: research

A nomogram for the prediction of cerebrovascular disease among patients with brain necrosis after radiotherapy for nasopharyngeal carcinoma
In various cancer populations, radiotherapy is associated with the development of vascular disease [1 –4]. Previous studies have established an increased incidence of carotid stenosis (CAS) and ischemic stroke in patients with head and neck cancer treated with radiotherapy [4,5]. A study of 6862 patients (age>65  years) showed that five-year incidence of cerebrovascular events was 19% in patients treated with radiotherapy alone compared with 14% in patients treated with surgery plus radiotherapy; the corresponding ten-year incidence were 34% and 25%, respectively [4].
Source: Radiotherapy and Oncology - December 21, 2018 Category: Radiology Authors: Jinhua Cai, Jinping Cheng, Honghong Li, Wei-Jye Lin, Yi Li, Xiaohuang Zhuo, Xiaolong Huang, Charles B. Simone, Wilbert S. Aronow, Edward L.W. Chow, Yamei Tang Tags: Original Article Source Type: research

Tu1115 PERCUTANEOUS ENDOSCOPIC GASTROSTOMY (PEG) IS ASSOCIATED WITH BETTER OUTCOMES AS COMPARED TO INTERVENTIONAL RADIOLOGY (IR) GUIDED AND SURGICAL GASTROSTOMIES: INSIGHTS FROM THE NATIONWIDE INPATIENT SAMPLE
Gastrostomy is a commonly performed procedure for enteral feeding in patients with diverse conditions such as malnutrition, stroke, dementia, Parkinsonism and other neurodegenerative diseases as well as head and neck and upper gastrointestinal cancers. PEG is usually preferred but IR guided and surgical gastrostomies are often performed based on patient related factors and local practice preferences. The aim of our study was to review demographic and clinical characteristics of patients undergoing gastrostomies in the inpatient setting.
Source: Gastrointestinal Endoscopy - May 31, 2019 Category: Gastroenterology Authors: Ishani Shah, Abhishek Bhurwal, Harsh Mehta, Shruti Mony, Ananya Das Tags: Tuesday abstract Source Type: research

Longitudinal atherosclerotic changes after radio(chemo)therapy of hypopharyngeal carcinoma
This study aimed at a closer characterization of this damage and its development in time with a longitudi...
Source: Radiation Oncology - May 7, 2020 Category: Cancer & Oncology Authors: Cristoforo Simonetto, Michael Mayinger, Thamer Ahmed, Kai Borm, Pavel Kundr át, Steffi Pigorsch, Jan Christian Kaiser and Stephanie E. Combs Tags: Research Source Type: research