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Cancer: Non-Small Cell Lung Cancer

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Total 28 results found since Jan 2013.

Cumulative Incidence of Thromboembolism and Prognostic Impact of Stroke in < em > BRAF < /em > V600E-mutant Non-small-cell Lung Cancer
CONCLUSION: A substantial proportion of patients with BRAF V600E-mutant lung cancer experienced thromboembolism during their disease course. CRS of undetermined source may predict a worse prognosis in this population.PMID:36697098 | DOI:10.21873/anticanres.16237
Source: Cell Research - January 25, 2023 Category: Cytology Authors: Sho Yamada Akimasa Sekine Eri Hagiwara Yoko Onodera Erina Tabata Satoshi Ikeda Hideya Kitamura Tomohisa Baba Shigeru Komatsu Takashi Ogura Source Type: research

Acute ischaemic stroke and myocardial infarction after chemotherapy with vinorelbine for non-small cell lung cancer: a case report.
We report about a 70-year-old male with metastatic non-small cell lung cancer who received vinorelbine as an outpatient. The patient presents with a cardiovascular risk profile. He was admitted to the hospital 3 days later with acute left-sided hemiplegia and hemianopia. Brain computed tomography (CT) demonstrated acute right hemispheric ischaemic stroke. Nine days after admission, the patient additionally suffered ST elevation myocardial infarction. A coronary angiogram demonstrated high grade stenosis of the right coronary artery treated with two bare-metal stents. Caution should be noted in patients who present with a c...
Source: Journal of Chemotherapy - November 18, 2015 Category: Cancer & Oncology Tags: J Chemother Source Type: research

Antiphospholipid Syndrome-induced Ischemic Stroke Following Pembrolizumab: case report and systematic review
We report a case of a patient treated with pembrolizumab who developed an acute ischemic stroke (AIS) as manifestation of immunotherapy-induced antiphospholipid syndrome (APS) and provide a systematic review of the literature.
Source: Lung Cancer - August 3, 2021 Category: Cancer & Oncology Authors: Vito Tota, Marie Dagonnier, Didier Wery, Laure Binet, Nathalie Nagy, Val érie Durieux, Marie Diaz, Jose-Antonio Elosegi, Stéphane Holbrechts Tags: Review Source Type: research

Poorly Differentiated Lung Cancer with Intracardiac Extension Causing Malignant Stroke in a Peritoneal Dialysis Patient: a Case Report
SN Compr Clin Med. 2022;4(1):255. doi: 10.1007/s42399-022-01331-w. Epub 2022 Nov 14.ABSTRACTCardiac involvement occurs in an almost one quarter of all the patients with lung cancer. Lymphatogenous spread is a more common route of tumor dissemination than the hematogenous spread. It was a retrospective case report. We hereby report a case of myocardial involvement by non-small cell lung cancer leading to an uncommon presentation of a malignant stroke and death in a peritoneal dialysis patient.PMID:36404986 | PMC:PMC9662106 | DOI:10.1007/s42399-022-01331-w
Source: Clinical Lung Cancer - November 21, 2022 Category: Cancer & Oncology Authors: Sahil Bagai Vipra Malik Pallavi Prasad Priyanka Singh Amit Sahu Dinesh Khullar Source Type: research

EPMA-World Congress 2015
Table of contents A1 Predictive and prognostic biomarker panel for targeted application of radioembolisation improving individual outcomes in hepatocellular carcinoma Jella-Andrea Abraham, Olga Golubnitschaja A2 Integrated market access approach amplifying value of “Rx-CDx” Ildar Akhmetov A3 Disaster response: an opportunity to improve global healthcare Russell J. Andrews, Leonidas Quintana A4 USA PPPM: proscriptive, profligate, profiteering medicine-good for 1 % wealthy, not for 99 % unhealthy Russell J. Andrews A5 The role of ...
Source: EPMA Journal - May 8, 2016 Category: Global & Universal Source Type: research

P-132 * bronchial sleeve resection or pneumonectomy for non-small-cell lung cancer: a propensity matched analysis of long-term survival and quality of life
Conclusions: During the 5-year follow-up, pneumonectomy and sleeve lobectomy showed no significant differences in cancer-specific survival or in quality of life. However, thereafter sleeve lobectomy patients showed better survival. This advocates the use of sleeve lobectomy in central non-small-cell lung cancer when feasible. Disclosure: No significant relationships.
Source: Interactive CardioVascular and Thoracic Surgery - June 9, 2014 Category: Cardiovascular & Thoracic Surgery Authors: Andersson, S. E. M., Ilonen, I. K., Rasanen, J. V., Sihvo, E. I., Salo, J. A. Tags: SESSION VII: MODERATED POSTERS Source Type: research

Synchronous cerebral arteriovenous malformation and lung adenocarcinoma carcinoma brain metastases: A case study and literature review.
CONCLUSION: This case represents a previously undocumented confluence of cranial AVM that initially masked a non-small cell lung cancer brain metastasis. PMID: 30638546 [PubMed - as supplied by publisher]
Source: Neurochirurgie - January 15, 2019 Category: Neurosurgery Tags: Neurochirurgie Source Type: research

Early ambulatory palliative care visits focus on psychosocial elements such as building rapport and coping, as well as managing symptoms and enhancing illness understanding
This study has had significant impact, but many professionals have asked for more details about palliative care interventions. Findings from the present study will help define what palliative care specifically provides. Context Professional organisations in the fields of oncology, such as the American Society of Clinical Oncology2 and palliative care, including the American Academy of Hospice and Palliative Medicine, have articulated the need for palliative care to be integrated into disease-focused care. There has been a wide international interest in this area as well. Achieving this aim will require a greater understanding...
Source: Evidence-Based Nursing - March 14, 2014 Category: Nursing Authors: Ferrell, B. Tags: End of life decisions (geriatric medicine), Adult nursing, Stroke, Lung cancer (oncology), End of life decisions (palliative care), Hospice, Lung cancer (respiratory medicine), End of life decisions (ethics), Resuscitation, Information management Source Type: research

P-154 * bilobectomy for non-small-cell lung cancer: results of a multicentre study on 425 cases
Conclusions: Bilobectomy is associated with increased morbidity. Five-year survival is influenced by tumour stage and completeness of resection. Worse survival occurs in adenocarcinoma and bronchus intermedius involvement. Disclosure: No significant relationships.
Source: Interactive CardioVascular and Thoracic Surgery - June 9, 2014 Category: Cardiovascular & Thoracic Surgery Authors: Filosso, P. L., Welter, S., Rena, O., Ampollini, L., Siedlecka, D., Avaro, J. P., Anile, M., Margaritora, S., Pischik, V., Thomas, P. Tags: SESSION VII: MODERATED POSTERS Source Type: research

Bm-19 * symptomatic and economic burden of brain metastases in patients with alk+ nsclc
CONCLUSIONS: BM presents a substantial symptomatic and economic burden in patients with ALK+ NSCLC. Given the large percentage of ALK+ NSCLC patients who will eventually develop BM, this highlights an important unmet need.
Source: Neuro-Oncology - November 3, 2014 Category: Cancer & Oncology Authors: Macalalad, A., Sasane, M., Zhang, J., Culver, K., Dea, K., Nitulescu, R., Wu, E., Guerin, A. Tags: BRAIN METASTASES (CLINICAL AND/OR LABORATORY RESEARCH) Source Type: research

Neuron-Specific Enolase as a Biomarker: Biochemical and Clinical Aspects.
Authors: Isgrò MA, Bottoni P, Scatena R Abstract Neuron-specific enolase (NSE) is known to be a cell specific isoenzyme of the glycolytic enzyme enolase. In vertebrate organisms three isozymes of enolase, expressed by different genes, are present: enolase α is ubiquitous; enolase β is muscle-specific and enolase γ is neuron-specific. The expression of NSE, which occurs as γγ- and αγ-dimer, is a late event in neural differentiation, thus making it a useful index of neural maturation.NSE is a highly specific marker for neurons and peripheral neuroendocrine cells. As a result of the findings of NSE in specific...
Source: Advances in Experimental Medicine and Biology - November 6, 2015 Category: Research Tags: Adv Exp Med Biol Source Type: research

Impact of Lifestyle Diseases on Postoperative Complications and Survival in Elderly Patients with Stage I Non-Small Cell Lung Cancer.
CONCLUSION: This study demonstrated that the presence of a lifestyle disease was a significant prognostic factor for postoperative complications, but not of survival, in elderly patients with stage I NSCLC. Therefore, postoperative complications may be influenced by the presence of a lifestyle disease. PMID: 28382266 [PubMed - in process]
Source: Korean Journal of Thoracic and Cardiovascular Surgery - April 7, 2017 Category: Cardiovascular & Thoracic Surgery Tags: Korean J Thorac Cardiovasc Surg Source Type: research

The Vertebral Body Infarct Sign: A Case of Thoracic Spinal Cord Ischemic Stroke (P3.292)
Conclusions:While the vertebral body infarct sign is often recognized by neuro-radiologists, it is still relatively unknown to practicing neurologists. Early recognition of spinal cord infarct allows for timely evaluation for precipitating factors and initiation of secondary preventative therapies to decrease risk of further vascular events.Disclosure: Dr. Chan has nothing to disclose. Dr. Chan has nothing to disclose. Dr. Farooque has nothing to disclose. Dr. Nowak has nothing to disclose.
Source: Neurology - April 17, 2017 Category: Neurology Authors: Chan, D., Chan, A., Farooque, P., Nowak, R. Tags: Cerebrovascular Disease Case Reports II Source Type: research

Connecting Metainflammation and Neuroinflammation Through the PTN-MK-RPTP β/ζ Axis: Relevance in Therapeutic Development
Conclusion The expression of the components of the PTN-MK-RPTPβ/ζ axis in immune cells and in inflammatory diseases suggests important roles for this axis in inflammation. Pleiotrophin has been recently identified as a limiting factor of metainflammation, a chronic pathological state that contributes to neuroinflammation and neurodegeneration. Pleiotrophin also seems to potentiate acute neuroinflammation independently of the inflammatory stimulus while MK seems to play different -even opposite- roles in acute neuroinflammation depending on the stimulus. Which are the functions of MK and PTN in chronic neuroi...
Source: Frontiers in Pharmacology - April 11, 2019 Category: Drugs & Pharmacology Source Type: research