Comparative effectiveness of chemotherapy in different histological types of pancreatic cancer: a PSM-based study using the SEER database
This study aimed to compare the effectiveness of chemotherapy in different histological types of pancreatic cancer using data collected from the Surveillance, Epidemiology, and End Results (SEER) database. Patients who were diagnosed with pancreatic cancer between 2004 and 2015 were selected from the SEER database. Propensity score matching (PSM) was employed to minimize the selection bias. The Kaplan-Meier survival curves and the log-rank test were utilized to compare the overall survival (OS) and cancer-specific survival (CSS) among different groups. Of the 7,653 pancreatic cancer patients, both OS and CSS were higher in...
Source: Journal of Chemotherapy - March 14, 2024 Category: Cancer & Oncology Authors: Canhua Luo Linfeng Fan Weijian Lun Miaomiao Ma Leshi Liang Changhui Yu Source Type: research

Evaluation of predictors of third-generation cephalosporin non-susceptibility and factors affecting recurrence or death in bacteremia caused by < em > Citrobacter freundii < /em > complex < em > , Enterobacter cloacae < /em > complex, and < em > Klebsiella aerogenes < /em >
J Chemother. 2024 Mar 7:1-11. doi: 10.1080/1120009X.2024.2323326. Online ahead of print.ABSTRACTFactors involved in the susceptibility of third-generation cephalosporins (3GCs) to bacteremia caused by Citrobacter freundii complex, Enterobacter cloacae complex, and Klebsiella aerogenes were investigated based on a case-case-control design. Antimicrobial therapy administered 30 days prior to bacteremia and hospitalization within 90 days were common risk factors for the 3GC susceptible and 3GC non-susceptible groups, while hospitalization from an institution or another hospital was a specific risk factor for the 3GC non-susce...
Source: Journal of Chemotherapy - March 7, 2024 Category: Cancer & Oncology Authors: Kazuhiro Kobayashi Atsuko Hata Waki Imoto Shigeki Kakuno Wataru Shibata Koichi Yamada Hiroshi Kawaguchi Norihiro Sakurai Toshikazu Ito Kazuya Uenoyama Tamotsu Takahashi Satoru Ueda Toshiro Katayama Masahide Onoue Hiroshi Kakeya Source Type: research

Intravesical sequential gemcitabine/docetaxel for non-muscle invasive bladder cancer: tips and tricks for better efficacy and tolerability
J Chemother. 2024 Mar 4:1-4. doi: 10.1080/1120009X.2024.2325765. Online ahead of print.NO ABSTRACTPMID:38439550 | DOI:10.1080/1120009X.2024.2325765 (Source: Journal of Chemotherapy)
Source: Journal of Chemotherapy - March 5, 2024 Category: Cancer & Oncology Authors: Mohamad Abou Chakra Mohamad Moussa Michael A O'Donnell Source Type: research

Antimicrobial dosing recommendations during continuous renal replacement therapy: different databases, different doses
In this study, we aimed to compare current databases that are frequently used to adjust CRRT dosages of antimicrobial drugs with the gold standard. The dosage recommendations from various databases for antimicrobial drugs eliminated by CRRT were investigated. The book 'Renal Pharmacotherapy: Dosage Adjustment of Medications Eliminated by the Kidneys' was chosen as the gold standard. There were variations in the databases. Micromedex, UpToDate, and Sanford had similar rates to the gold standard of 45%, 35%, and 30%, respectively. The Micromedex database shows the most similar results to the gold standard source. In addition...
Source: Journal of Chemotherapy - February 27, 2024 Category: Cancer & Oncology Authors: Aysel Pehlivanli Tu ğba Yanik Yalçin Fatma İrem Yeşiler Helin Şahintürk Özlem Kurt Azap P ınar Zeyneloğlu Bilgen Ba şgut Source Type: research