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Total 498 results found since Jan 2013.
Neutrophil Recruitment in Arterial Thrombus and Characteristics of Stroke Patients with Neutrophil-Rich Thrombus
CONCLUSION: Neutrophils were recruited and increased in arterial thrombosis in a time-dependent manner; however, they were not associated with the growth of formed thrombi. Neutrophil fractions in the thrombi of stroke patients appeared to be associated with atrial fibrillation and erythrocyte fraction.PMID:36303310 | PMC:PMC9629897 | DOI:10.3349/ymj.2022.0328
Source: Yonsei Medical Journal - October 28, 2022 Category: Universities & Medical Training Authors: Myoung-Jin Cha Jimin Ha Hyungwoo Lee Il Kwon Sungeun Kim Young Dae Kim Hyo Suk Nam Hye Sun Lee Tae-Jin Song Hyun-Jung Choi Ji Hoe Heo Source Type: research
Comprehensive evaluation of the mechanism of Gastrodia elata Blume in ameliorating cerebral ischemia –reperfusion injury based on integrating fecal metabonomics and 16S rDNA sequencing
Gastrodia elata Blume was used to treat stroke and headaches caused by “Feng” for thousands of years. The present study has shown a significant effect of G. elata Blume in improving cerebral ischemia–reperfusion injury (CIRI). However, the mechanism of G. elata Blume in improving CIRI by regulating the intestinal flora has not been reported until now. This research aimed to comprehensively evaluate the mechanism of G. elata Blume in CIRI based on fecal metabolomics and 16S rDNA sequencing. The rat model with CIRI was created based on the Zea Longa method. Enzyme-linked immunosorbent assay (ELISA) was used to monitor ...
Source: Frontiers in cellular and infection microbiology - October 27, 2022 Category: Microbiology Source Type: research
Protective Effect of Ergothioneine Against Stroke in Rodent Models
AbstractErgothioneine (ET) is a naturally occurring antioxidant and cytoprotective agent that is synthesized by fungi and certain bacteria. Recent studies have shown a beneficial effect of ET on neurological functions, including cognition and animal models of depression. The aim of this study is to elucidate a possible effect of ET in rodent models of stroke. Post-ischemic intracerebroventricular (i.c.v.) infusion of ET significantly reduced brain infarct volume by as early as 1 day after infusion in rats, as shown by triphenyltetrazolium chloride (TTC) assay. There was a dose-dependent increase in protection, from 50 to...
Source: NeuroMolecular Medicine - October 19, 2022 Category: Neurology Source Type: research
A highly stable electrode with low electrode-skin impedance for wearable brain-computer interface
Biosens Bioelectron. 2022 Sep 28;218:114756. doi: 10.1016/j.bios.2022.114756. Online ahead of print.ABSTRACTTo date, brain-computer interfaces (BCIs) have proved to play a key role in many medical applications, for example, the rehabilitation of stroke patients. For post-stroke rehabilitation, the BCIs require the EEG electrodes to precisely translate the brain signals of patients into intended movements of the paralyzed limb for months. However, the gold standard silver/silver-chloride electrodes cannot satisfy the requirements for long-term stability and preparation-free recording capability in wearable EEG devices, thus...
Source: Biosensors and Bioelectronics - October 9, 2022 Category: Biotechnology Authors: Ju-Chun Hsieh Hussein Alawieh Yang Li Fumiaki Iwane Linran Zhao Richard Anderson Syed Ibtisam Abdullah Kai Wing Kevin Tang Wenliang Wang Ilya Pyatnitskiy Yaoyao Jia Jos é Del R Millán Huiliang Wang Source Type: research
Circular RNA circPRDX3 mediates neuronal survival apoptosis in ischemic stroke by targeting miR-641 and NPR3
CONCLUSION: Altogether, circPRDX3 inhibited the development of IS by sponging miR-641, hence increasing NPR3 expression and inactivating MAPK pathway. These results may aid in the search of potential therapy targets for IS.PMID:36208650 | DOI:10.1016/j.brainres.2022.148114
Source: Cell Research - October 8, 2022 Category: Cytology Authors: Weiping Chen Yangbo Zhang Min Yin Zhijuan Cheng Dandan Li Xin Luo Xu Liu Jianglong Tu Source Type: research
Efficacy of Fuyuan Xingshen Decoction Combined with Butylphthalide Sodium Chloride Injection in the Treatment of Acute Cerebral Infarction and Its Effect on Hemodynamics
CONCLUSIONS: Fuyuan Xingshen Decoction combined with butylphthalide sodium chloride injection can effectively improve patients' daily living ability, neurological function, cognitive function, and cerebral hemodynamics in the treatment of ACI, with good effect and safety.PMID:36193139 | PMC:PMC9526653 | DOI:10.1155/2022/2402040
Source: Evidence-based Complementary and Alternative Medicine - October 4, 2022 Category: Complementary Medicine Authors: Jiangang Ji Kai Yu Xinyu Zhang Wenting Liu Source Type: research
