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Total 554 results found since Jan 2013.

Effect of Supervised Training Therapy on Pulmonary Arterial Compliance and Stroke Volume in Severe Pulmonary Arterial Hypertension and Inoperable or Persistent Chronic Thromboembolic Pulmonary Hypertension
Conclusions: Our findings suggest that supervised exercise training may improve right ventricular function and PAC at the same time. Further prospective studies are needed to evaluate these findings.Respiration
Source: Respiration - March 25, 2021 Category: Respiratory Medicine Source Type: research

Development and validation of the World Health Organization disability Assessment Schedule 2.0 (WHODAS 2.0) Indonesian version in stroke survivors
CONCLUSIONS: The WHODAS 2.0 was adapted for use in Indonesia and showed good results for all six domains. Therefore, the Indonesian version of the WHODAS 2.0 can be applied to assess disability in Indonesian stroke survivors.Implications for rehabilitationThe WHO Disability Assessment Schedule 2.0 (WHODAS 2.0) was developed as a single, generic instrument for assessing the health status and disability in different cultures and settings.In this study, we adapted and validated an Indonesian version of the WHODAS 2.0 for stroke survivors in Indonesia.The WHODAS 2.0 was adapted for use in Indonesia and showed good results for ...
Source: Disability and Rehabilitation - March 22, 2021 Category: Rehabilitation Authors: Sri Yuliana Muhammad Muslih Jenny Sim Amelia Nur Vidyanti Ageng Brahmadhi Hsiu Ting Tsai Source Type: research

A Cohort Study of Anticholinergic Medication Burden and Incident Dementia and Stroke in Older Adults
ConclusionsHigh anticholinergic burden in initially healthy older people was associated with increased risk of incident dementia and ischemic stroke. A vascular effect may underlie this association. These findings highlight the importance of minimizing anticholinergic exposure in healthy older people.
Source: Journal of General Internal Medicine - March 22, 2021 Category: Internal Medicine Source Type: research

Hybrid artificial fish particle swarm optimizer and kernel extreme learning machine for type-II diabetes predictive model
AbstractThe World Health Organization(WHO) estimated that in 2016, 1.6 million deaths caused were due to diabetes. Precise and on-time diagnosis of type-II diabetes is crucial to reduce the risk of various diseases such as heart disease, stroke, kidney disease, diabetic retinopathy, diabetic neuropathy, and macrovascular problems. The non-invasive methods like machine learning are reliable and efficient in classifying the people subjected to type-II diabetics risk and healthy people into two different categories. This present study aims to develop a stacking-based integrated kernel extreme learning machine (KELM) model for...
Source: Medical and Biological Engineering and Computing - March 18, 2021 Category: Biomedical Engineering Source Type: research

Effects of eye-acupuncture combined with rehabilitation training for poststroke dyskinesia: A protocol for systematic review and meta-analysis
Introduction: Poststroke dyskinesia is the most common clinical symptom after stroke, which greatly affects the patients’ daily life. Eye-acupuncture is an effective method for stroke. And the rehabilitation training has been widely used for patients suffer from stroke. However, whether eye-acupuncture combined with rehabilitation training has greater clinical efficacy for poststroke dyskinesia is still unknown. Our aim in this systematic review was to evaluate the clinical efficacy of eye-acupuncture combined with rehabilitation training (EACRT) as a treatment for dyskinesia after stroke. Methods and analysis: ...
Source: Medicine - March 12, 2021 Category: Internal Medicine Tags: Research Article: Study Protocol Systematic Review Source Type: research

Cholinesterase inhibitors for vascular dementia and other vascular cognitive impairments: a network meta-analysis
CONCLUSIONS: We found moderate- to high-certainty evidence that donepezil 5 mg, donepezil 10 mg, and galantamine have a slight beneficial effect on cognition in people with VCI, although the size of the change is unlikely to be clinically important. Donepezil 10 mg and galantamine 16 to 24 mg are probably associated with more adverse events than placebo. The evidence for rivastigmine was less certain. The data suggest that donepezil 10 mg has the greatest effect on cognition, but at the cost of adverse effects. The effect is modest, but in the absence of any other treatments, people living with VCI may still wish to consid...
Source: Cochrane Database of Systematic Reviews - March 11, 2021 Category: General Medicine Authors: Ceri E Battle Azmil H Abdul-Rahim Susan D Shenkin Jonathan Hewitt Terry J Quinn Source Type: research

(Ultra-)long-acting insulin analogues for people with type 1 diabetes mellitus
CONCLUSIONS: Comparing insulin detemir with NPH insulin for T1DM showed lower risk of severe hypoglycaemia in favour of insulin detemir (moderate-certainty evidence). However, the 95% prediction interval indicated inconsistency in this finding. Both insulin detemir and insulin glargine compared with NPH insulin did not show benefits or harms for severe nocturnal hypoglycaemia. For all other main outcomes with overall low risk of bias and comparing insulin analogues with each other, there was no true beneficial or harmful effect for any intervention. Data on patient-important outcomes such as QoL, macrovascular and microvas...
Source: Cochrane Database of Systematic Reviews - March 4, 2021 Category: General Medicine Authors: Bianca Hemmingsen Maria-Inti Metzendorf Bernd Richter Source Type: research

The effect of occupational exposure to noise on ischaemic heart disease, stroke and hypertension: A systematic review and meta-analysis from the WHO/ILO Joint Estimates of the Work-Related Burden of Disease and Injury
CONCLUSIONS: For acquiring IHD, we judged the existing body of evidence from human data to provide "limited evidence of harmfulness"; a positive relationship is observed between exposure and outcome where chance, bias, and confounding cannot be ruled out with reasonable confidence. For all other included outcomes, the bodies of evidence were judged as "inadequate evidence of harmfulness". Producing estimates for the burden of CVD attributable to occupational exposure to noise appears to not be evidence-based at this time.PROTOCOL IDENTIFIER: 10.1016/j.envint.2018.09.040.PROSPERO REGISTRATION NUMBER: CRD42018092272.PMID:336...
Source: Environment International - February 22, 2021 Category: Environmental Health Authors: Liliane R Teixeira Frank Pega Angel M Dzhambov Alicja Bortkiewicz Denise T Correa da Silva Carlos A F de Andrade Elzbieta Gadzicka Kishor Hadkhale Sergio Iavicoli Martha S Mart ínez-Silveira Ma łgorzata Pawlaczyk-Łuszczyńska Bruna M Rondinone Jadwiga Source Type: research

Stroke Epidemiology in Oceania: A Review
Conclusions: Stroke is a major healthcare problem in Oceania. Variations in stroke epidemiology are found between countries in Oceania. Data are lacking in some; more research into the burden of stroke in Oceania is needed. With the expected increase in life expectancy and vascular risk factors, the burden of stroke in Oceania will likely rise. Some of the disparities in stroke burden may be addressed by great investment in healthcare.Neuroepidemiology
Source: Neuroepidemiology - February 18, 2021 Category: Epidemiology Source Type: research

Patches of different types for carotid patch angioplasty.
CONCLUSIONS: The number of outcome events is too small to allow conclusions, and more trial data are required to establish whether any differences do exist. Nevertheless, there is little to no difference in effect on perioperative and long-term ipsilateral stroke between vein and any synthetic patch material. Some evidence indicates that other synthetic patches (e.g. PTFE) may be superior to Dacron grafts in terms of perioperative stroke and TIA rates, and both early and late arterial re-stenosis and occlusion. Pseudoaneurysm formation may be more common after use of a vein patch than after use of a synthetic patch. Bovin...
Source: Cochrane Database of Systematic Reviews - February 18, 2021 Category: General Medicine Authors: Orrapin S, Benyakorn T, Howard DP, Siribumrungwong B, Rerkasem K Tags: Cochrane Database Syst Rev Source Type: research

Acupuncture combined with moxibustion for insomnia after stroke: A protocol for systematic review and meta analysis
Conclusion: The conclusion of our study will provide the updated evidence to judge the effectiveness and safety of acupuncture combined with moxibustion for the treatment of insomnia after stroke. Trial registration number: PROSPERO CRD42020216720.
Source: Medicine - January 22, 2021 Category: Internal Medicine Tags: Research Article: Study Protocol Systematic Review Source Type: research

Impact of salt intake reduction on CVD mortality in Costa Rica: A scenario modelling study
The objective of this study was to estimate the impact of reducing salt intake on CVD mortality in Costa Rica using a scenario simulation model. The Preventable Risk Integrated ModEl (PRIME) was used to estimate the number of deaths that would be averted or delayed in the Costa Rican population by following the national and the international guidelines to reduce salt consumption, according to two scenarios: A) 46% reduction and B) 15% reduction, both at an energy intake of 2171 kcal. The scenarios estimated that between 4% and 13%, respectively, of deaths due to CVD would be prevented or postponed. The hig hest percentages...
Source: PLoS One - January 12, 2021 Category: Biomedical Science Authors: Jaritza Vega-Solano Source Type: research

Reliability and Validity of the Korean Version of Stroke-Specific Quality of Life Questionnaire
CONCLUSIONS: The SSQOL-K is a valid and reliable scale to assess health-related quality of life in Korean stroke patients.
Source: Journal of Neuroscience Nursing - January 9, 2021 Category: Neuroscience Tags: Articles Source Type: research

Efficacy of individualized education in patients with type 2 diabetes mellitus: A randomized clinical study protocol
Conclusion: Individualized diabetes education may improve the clinical outcomes in patients with type 2 DM. Trial registration: The protocol was registered in Research Registry (researchregistry6232).
Source: Medicine - December 11, 2020 Category: Internal Medicine Tags: Research Article: Study Protocol Clinical Trial Source Type: research