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Total 554 results found since Jan 2013.

Effect of constraint-induced movement therapy on lower extremity motor dysfunction in post-stroke patients: A systematic review and meta-analysis
ConclusionCIMT effectively improves lower extremity motor dysfunction in post-stroke patients; however, the eligible studies were highly heterogeneous.Systematic review registration: https://www.crd.york.ac.uk/prospero/display_record.php?RecordID=277466.
Source: Frontiers in Neurology - November 21, 2022 Category: Neurology Source Type: research

COMIRESTROKE —A clinical study protocol for monitoring clinical effect and molecular biological readouts of COMprehensive Intensive REhabilitation program after STROKE: A four-arm parallel-group randomized double blinded controlled trial with a longitudinal design
In this study, four kinds of comprehensive inpatient rehabilitation with different management and content of physical therapy will be compared. Moreover, focus will be placed on the identification of novel biological molecules reflective of effective rehabilitation. Long non-coding RNAs (lncRNAs) are transcripts (>200 bps) of limited coding potential, which have recently been recognized as key factors in neuronal signaling pathways in ischemic stroke and as such, may provide a valuable readout of patient recovery and neuroprotection during therapeutic progression.Methods and analysisAdults after the first ischemic strok...
Source: Frontiers in Neurology - November 1, 2022 Category: Neurology Source Type: research

Mortality and Morbidity Effects of Long-Term Exposure to Low-Level PM < sub > 2.5 < /sub > , BC, NO < sub > 2 < /sub > , and O < sub > 3 < /sub > : An Analysis of European Cohorts in the ELAPSE Project
CONCLUSIONS: Long-term exposure to PM2.5, NO2, and BC was positively associated with natural-cause and cause-specific mortality in the pooled cohort and the administrative cohorts. Associations were found well below current limit values and guidelines for PM2.5 and NO2. Associations tended to be supralinear, with steeper slopes at low exposures with no indication of a threshold. Two-pollutant models documented the importance of characterizing the ambient mixture with both NO2 and PM2.5. We mostly found negative associations with O3. In two-pollutant models with NO2, the negative associations with O3 were attenuated to esse...
Source: Cancer Control - September 15, 2022 Category: Cancer & Oncology Authors: Brunekreef Bert Strak Maciej Chen Jie J Andersen Zorana Atkinson Richard Bauwelinck Mariska Bellander Tom Boutron Marie-Christine Brandt J ørgen Carey Iain Cesaroni Giulia Forastiere Francesco Fecht Daniela Gulliver John Hertel Ole Hoffmann Barbara de Ho Source Type: research

Incidence, lethality, and post-stroke functional status in different Brazilian macro-regions: The SAMBA study (analysis of stroke in multiple Brazilian areas)
ConclusionThis study expands the knowledge of stroke epidemiology in Brazil, a middle-income country with enormous socioeconomic and cultural diversity. The discrepancy observed regarding the impact of stroke in patients from Joinville and Sobral highlights the need to improve the strategic allocation of resources to meet the health priorities in each location.
Source: Frontiers in Neurology - September 15, 2022 Category: Neurology Source Type: research

Stroke in young adults, stroke types and risk factors: a case control study
Stroke is the second leading cause of death above the age of 60 years, and the fifth leading cause in people aged 15 to 59 years old as reported by the World Health Organization global burden of diseases. Stro...
Source: BMC Neurology - September 6, 2022 Category: Neurology Authors: Priscilla Namaganda, Jane Nakibuuka, Mark Kaddumukasa and Elly Katabira Tags: Research Source Type: research

Extreme Heat Makes It Hard for Kids To Be Active. But Exercise Is Crucial In a Warming World
Getting kids to be active in a modern world is a tough sell. It can be hard to compete with indoor comforts like video games, television, and air conditioning. Sweltering weather is another formidable barrier to kids getting enough physical activity, finds a new scientific review published in the journal Temperature that analyzed more than 150 studies. Children today are about 30% less aerobically fit than their parents were at their same age, leaving them less prepared to acclimate to a hotter, more extreme climate as they age, the study concluded. “The outside world is becoming more of an extreme environment for hu...
Source: TIME: Health - August 5, 2022 Category: Consumer Health News Authors: Tara Law Tags: Uncategorized Exercise & Fitness healthscienceclimate Source Type: news

Acute Occupational and Physical Therapy for COVID-19 Patients: A Retrospective Cohort Study
In March 2020, the World Health Organization (WHO) declared the novel coronavirus strain SARS-CoV2 (the virus causing COVID-19) a global pandemic.24 The severity of illness in those exhibiting symptoms ranges from mild (cough, shortness of breath, fatigue) to severe (acute respiratory distress syndrome (ARDS), thrombosis, stroke, and death).4,11 Patients have also acquired acute polyradiculoneuritis (Guillain Barre syndrome) at a disproportionately high rate, contributing to functional limitations that require specialized and intensive rehabilitation.
Source: Archives of Physical Medicine and Rehabilitation - July 31, 2022 Category: Rehabilitation Authors: Katie Coakley, Laura Friedman, Kaitlyn McLoughlin, Amy Wozniak, Paul Hutchison Tags: Original Research Source Type: research

Antiplatelet agents and anticoagulants for hypertension
CONCLUSIONS: There is no evidence that antiplatelet therapy modifies mortality in patients with elevated BP for primary prevention. ASA reduced the risk of cardiovascular events and increased the risk of major bleeding events. Antiplatelet therapy with ASA probably reduces the risk of non-fatal and all cardiovascular events when compared to clopidogrel. Clopidogrel increases the risk of major bleeding events compared to ASA in patients with elevated BP for secondary prevention. There is no evidence that warfarin modifies mortality in patients with elevated BP for secondary prevention. The benefits and harms of the newer dr...
Source: Cochrane Database of Systematic Reviews - July 28, 2022 Category: General Medicine Authors: Eduard Shantsila Monika Kozie ł-Siołkowska Gregory Yh Lip Source Type: research

Incidence and characteristics of stroke in Zanzibar –a hospital-based prospective study in a low-income island population
ConclusionZanzibar has high incidence of hospitalization for stroke, indicating a very high population incidence of stroke. The proportion of strokes due to ICH is substantially higher than in high-income countries. Most stroke patients had been in contact with health care providers prior to stroke onset and been diagnosed with hypertension. However, few were using antihypertensive medication at the time of stroke onset.www.ClinicalTrial.gov registration NCT04095806.
Source: Frontiers in Neurology - July 28, 2022 Category: Neurology Source Type: research

Grading of Japanese Diet Intakes by 24-Hour Urine Analysis of Taurine and Soy Isoflavones in Relation to Cardiovascular Risks
In conclusion, the higher the J score, which corresponds to Japanese dietary habits, the lower the BMI and cholesterol levels, as well as mortality rate from coronary heart disease, but the higher the average life expectancy among the Japanese. However, these higher J scorings were associated with high-salt intake and high Na/K ratios; therefore, they contributed to high blood pressure and high mortality rate caused by stroke in Japan. These results indicate that low-salt intake should be recommended to the Japanese who are consuming seafood and soy regularly in order to maintain lower blood pressure and to extend healthy ...
Source: Advances in Experimental Medicine and Biology - July 26, 2022 Category: Research Authors: Mari Mori Miki Sagara Hideki Mori Yukio Yamori Source Type: research

P-006 The 'hub-spoke telemedicine model in a large cohort of stroke patients
ConclusionTele-stroke networks have proven to be a pivotal development in the treatment of strokes, especially those that are remote. With the additional expertise and the shorter duration from onset to diagnosis to treatment, these networks have substantially improved patient care and decreased healthcare costs, avoiding unnecessary transfers from spoke hospitals to hub.Abstract P-006 Figure 1Abstract P-006 Figure 2Disclosures K. El Naamani: None. N. Herial: None. R. Abbas: None. G. Sioutas: None. A. Amllay: None. A. Munoz: None. A. Sweid: None. C. Morse: None. D. Moylan: None. D. Joffe: None. M. Knapp: None. S. Tjoumakar...
Source: Journal of NeuroInterventional Surgery - July 23, 2022 Category: Neurosurgery Authors: El Naamani, K., Herial, N., Abbas, R., Sioutas, G., Amllay, A., Munoz, A., Sweid, A., Morse, C., Moylan, D., Joffe, D., Knapp, M., Tjoumakaris, S., Gooch, M., Rosenwasser, R., Jabbour, P. Tags: SNIS 19th annual meeting oral poster abstracts Source Type: research

Climate Experts Are Testing New Ways To Reach the People Most Affected by Extreme Heat
As heat waves become longer, hotter, and more widespread across the planet, human responses to them are becoming increasingly local and specialized. Both scientific researchers and government officials are finding that the best strategies to keep cool are ones that are specially tailored to a community. That may seem obvious, given that outdoor laborers need different cooling resources than school teachers, for instance. But existing national and regional policies aren’t always that fine tuned—and they run the risk of wasting resources or missing the most vulnerable people. [time-brightcove not-tgx=”tru...
Source: TIME: Health - July 19, 2022 Category: Consumer Health News Authors: Emily Barone Tags: Uncategorized climate climate change Climate Is Everything extreme weather healthscienceclimate Source Type: news

A Clinical and Physiological Prospective Observational Study on the Management of Pediatric Shock in the Post-Fluid Expansion as Supportive Therapy Trial Era*
CONCLUSIONS: Maintenance-only fluid therapy normalized clinical and myocardial perturbations in shock without compromising cardiac or hemodynamic function whereas fluid-bolus management of WHO shock resulted in high fatality. Troponin and lactate biomarkers of cardiac dysfunction could be promising outcome predictors in pediatric septic shock in resource-limited settings.
Source: Pediatric Critical Care Medicine - July 1, 2022 Category: Pediatrics Tags: Feature Articles Source Type: research