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Total 130 results found since Jan 2013.

Ischemic Stroke Profile, Risk Factors, and Outcomes in India Brief Report
Background and Purpose—The Indo-US Collaborative Stroke Project was designed to characterize ischemic stroke across 5 high-volume academic tertiary hospitals in India.Methods—From January 2012 to August 2014, research coordinators and physician coinvestigators prospectively collected data on 2066 patients with ischemic stroke admitted
Source: Stroke - December 22, 2017 Category: Neurology Authors: P.N. Sylaja, Jeyaraj Durai Pandian, Subhash Kaul, M.V. Padma Srivastava, Dheeraj Khurana, Lee H. Schwamm, Praveen Kesav, Deepti Arora, Aman Pannu, Tijy K. Thankachan, Aneesh B. Singhal Tags: Ischemic Stroke Brief Reports Source Type: research

Academic Year-end Changeover and Stroke Outcomes
Lower quality of care and poorer outcomes are suspected when new trainees (eg, residents) start in July in teaching hospitals, the so-called “the July effect.” We evaluated outcomes and processes of care among patients with an acute ischemic stroke (AIS) admitted in July versus other 11 months of the year.
Source: Journal of Stroke and Cerebrovascular Diseases - December 23, 2014 Category: Neurology Authors: Tai Hwan Park, Donald A. Redelmeier, Shudong Li, Jitphapa Pongmoragot, Gustavo Saposnik, Investigators of the Registry of the Canadian Stroke network (RCSN) for the Stroke Outcomes Research (SORCan) Working Group Source Type: research

Aspiration Pneumonia in Adults Hospitalized With Stroke at a Large Academic Hospital in Zambia
Discussion PSAP is common and life threatening in Zambia, especially among older participants with severe stroke presentations. PSAP was associated with significantly increased mortality independent of initial stroke severity, suggesting that interventions to mitigate PSAP may improve stroke outcomes in Zambia and other resource-limited settings.
Source: Neurology Clinical Practice - December 13, 2021 Category: Neurology Authors: Prust, M. L., Nutakki, A., Habanyama, G., Chishimba, L., Chomba, M., Mataa, M., Yumbe, K., Zimba, S., Gottesman, R. F., Bahouth, M. N., Saylor, D. R. Tags: All Cerebrovascular disease/Stroke, All global neurology Research Source Type: research

A Stroke Care Model at an Academic, Comprehensive Stroke Center During the 2020 COVID-19 Pandemic
The COVID-19 pandemic has required the adaptation of hyperacute stroke care (including stroke code pathways) and hospital stroke management. There remains a need to provide rapid and comprehensive assessment to acute stroke patients while reducing the risk of COVID-19 exposure, protecting healthcare providers, and preserving personal protective equipment (PPE) supplies. While the COVID infection is typically not a primary cerebrovascular condition, the downstream effects of this pandemic force adjustments to stroke care pathways to maintain optimal stroke patient outcomes.
Source: Journal of Stroke and Cerebrovascular Diseases - May 6, 2020 Category: Neurology Authors: Dawn Meyer, Brett C. Meyer, Karen S. Rapp, Royya Modir, Kunal Agrawal, Lovella Hailey, Melissa Mortin, Richard Lane, Tamra Ranasinghe, Brian Sorace, Tara D. von Kleist, Emily Perrinez, Mohammed Nabulsi, Thomas Hemmen Source Type: research

Racial and Gender Differences in Stroke Severity, Outcomes, and Treatment in Patients with Acute Ischemic Stroke
Background: Previous research has indicated that women and blacks have worse outcomes after acute ischemic stroke (AIS). Little research has been done to investigate the combined influence of race and gender in the presentation, treatment, and outcome of patients with AIS. We sought to determine the association of race and gender on initial stroke severity, thrombolysis, and functional outcome after AIS.Methods: AIS patients who presented to 2 academic medical centers in the United States (2004-2011) were identified through prospective registries. In-hospital strokes were excluded. Stroke severity, measured by admission Na...
Source: Journal of Stroke and Cerebrovascular Diseases - January 27, 2014 Category: Neurology Authors: Amelia K. Boehme, James E. Siegler, Michael T. Mullen, Karen C. Albright, Michael J. Lyerly, Dominique J. Monlezun, Erica M. Jones, Rikki Tanner, Nicole R. Gonzales, T. Mark Beasley, James C. Grotta, Sean I. Savitz, Sheryl Martin-Schild Tags: Original Articles Source Type: research

Saving Vanessa, part 1: A mystery rash, a stroke and an epic rescue
Vanessa’s rash first appeared on her arms and legs when she 3 or 4 months old. It was red and bumpy and went away when she was sick with a virus, which happened often. Then it would come back. The dermatology team she saw at Boston Children’s Hospital was puzzled. “I was expecting they were going to think it was nothing, but they took it very seriously,” says Katherine Bell, one of Vanessa’s mothers. “They took a biopsy and very quickly realized they had no idea what it was.” Vanessa’s case was even featured at a regional dermatology conference where doctors take up mystery patients. “A hundred to 150 der...
Source: Thrive, Children's Hospital Boston - July 25, 2017 Category: Pediatrics Authors: Nancy Fliesler Tags: Diseases & Conditions Our Patients’ Stories Dr. Carolyn Rogers Dr. Pui Lee Dr. Robert Sundel Dr. Scellig Stone Dr. Todd Lyons stroke Source Type: news

Reliability of the Acutely Estimated Premorbid Modified Rankin Scale for Stroke Treatment Decision Making
Background: Premorbid functional status is an important factor in acute stroke treatment decision making. Determining the modified Rankin Score (mRS) accurately may be difficult due to deficits from stroke and lack of collateral information in the acute setting. Data on the reliability of the premorbid mRS in “real-world” practice outside of clinical trial or registry settings are limited. Methods: A retrospective study at a high volume academic primary stroke center. For patients with acute ischemic stroke treated with alteplase between July 2012 and July 2016, hospital electronic records were revie wed for detailed i...
Source: Journal of Stroke and Cerebrovascular Diseases - January 9, 2019 Category: Neurology Authors: WenWen Zhang, Skye Coote, Tanya Frost, Helen M. Dewey, Phillip M. Choi Source Type: research

Establishing the need for a stroke unit at Chris Hani Baragwanath Academic Hospital in South Africa
Stroke in Africa is a growing and neglected crisis with strokes more than doubling in low to middle income countries in the last four decades. Despite this growing threat to healthcare systems, implementation of stroke models of care in hospitals is lacking with most stroke patients being managed as part of a general medical service. Stroke units have shown to decrease mortality, reduce length of stay in hospital (LOS), and improve patient outcomes.
Source: Journal of Stroke and Cerebrovascular Diseases - March 30, 2023 Category: Neurology Authors: Stephanie Pillay, Azra Hoosen, Fiona Breytenbach, Roxann Redant, Nadia Umuneza, Sameera Haffejee, Zvifadzo Matsena-Zingoni, Kganetso Sekome Source Type: research

A Genetic Variant of miR-34a Contributes to Susceptibility of Ischemic Stroke Among Chinese Population
This study was supported by National Natural Science Foundation of China (Nos. 81560552, 81260234), Natural Science Foundation of Guangxi Zhuang Autonomous Region (CN) (2017JJA180826), Innovation Project of Guangxi Graduate Education (CN) (201601009) and Key Laboratory Open Project Fund of Guangxi Zhuang Autonomous Region (CN) (kfkt20160064). Conflict of Interest Statement The authors declare that the research was conducted in the absence of any commercial or financial relationships that could be construed as a potential conflict of interest. Supplementary Material The Supplementary Material for this article can be fou...
Source: Frontiers in Physiology - April 23, 2019 Category: Physiology Source Type: research

UCLA, USC get $2M to develop stroke center network in Southland
Stroke is the second leading cause of death in Los Angeles County and the fourth in the U.S. In order to cut those numbers, it's imperative that new treatments be developed and refined for stroke prevention, acute therapy and recovery after stroke.   Now, a three-way partnership between the UCLA Stroke Center at Ronald Reagan UCLA Medical Center, the USC Comprehensive Stroke and Cerebrovascular Center at Keck Medicine of USC, and UC Irvine has been awarded a $2 million grant from the National Institutes of Health to address these three stroke priorities.   Together, the three universities will form the Los A...
Source: UCLA Newsroom: Health Sciences - October 15, 2013 Category: Universities & Medical Training Source Type: news

Cardiac Imaging Within Emergency CT Angiography for Acute Stroke Can Detect Atrial Clots
This study was approved by the ethics committee of the medical faculty of the Ruhr University Bochum. FIGURE 1 Figure 1. Flow chart showing the selection of the study population. Results A total of 59 patients underwent emergency CCTA (Figure 2A) for suspected stroke, of which 44 received the final diagnosis ischemic stroke. There were 17 patients who had ischemic stroke or TIA and known or newly diagnosed atrial fibrillation (Table 1; mean age: 77.5 years, standard deviation: 8.4 years; 53% female). As hypothesized, intracardiac thrombi could be visualized: once in an artificially occluded left atrial appe...
Source: Frontiers in Neurology - April 9, 2019 Category: Neurology Source Type: research

UCLA Stroke Center awarded 'comprehensive stroke center' certification
The UCLA Stroke Center has been certified as a comprehensive stroke center by the Joint Commission and the American Heart Association/American Stroke Association. The center, part of UCLA Health and the UCLA Department of Neurology, is one of the first 12 stroke centers in the nation to receive the prestigious designation.   The certification, which confirms that the UCLA Stroke Center has met the highest national standards for safety and quality of care, further enhances the center's national reputation as an innovator in clinical care.   "This is a true team effort, reflecting the efforts of over 200 physicians...
Source: UCLA Newsroom: Health Sciences - March 12, 2013 Category: Universities & Medical Training Source Type: news

Ipsilateral hippocampal atrophy is associated with long‐term memory dysfunction after ischemic stroke in young adults
Abstract Memory impairment after stroke in young adults is poorly understood. In elderly stroke survivors memory impairments and the concomitant loss of hippocampal volume are usually explained by coexisting neurodegenerative disease (e.g., amyloid pathology) in interaction with stroke. However, neurodegenerative disease, such as amyloid pathology, is generally absent at young age. Accumulating evidence suggests that infarction itself may cause secondary neurodegeneration in remote areas. Therefore, we investigated the relation between long‐term memory performance and hippocampal volume in young patients with first‐eve...
Source: Human Brain Mapping - March 1, 2015 Category: Neurology Authors: Pauline Schaapsmeerders, Inge W.M. van Uden, Anil M. Tuladhar, Noortje A.M. Maaijwee, Ewoud J. van Dijk, Loes C.A. Rutten‐Jacobs, Renate M. Arntz, Hennie C. Schoonderwaldt, Lucille D.A. Dorresteijn, Frank‐Erik de Leeuw, Roy P.C. Kessels Tags: Research Article Source Type: research

Value of routine echocardiography in the management of stroke.
Abstract BACKGROUND: Transthoracic echocardiography is routinely performed in patients with stroke or transient ischemic attack (TIA) to help plan secondary stroke management, but recent data evaluating its usefulness in this context are lacking. We sought to evaluate the value of echocardiography for identifying clinically actionable findings for secondary stroke prevention. METHODS: We conducted a multicentre cohort study of patients admitted to hospital with stroke or TIA between 2010 and 2015 at 2 academic hospitals in Toronto, Ontario, Canada. Clinically actionable echocardiographic findings for secondar...
Source: cmaj - August 5, 2019 Category: General Medicine Authors: Fralick M, Goldberg N, Rohailla S, Guo Y, Burke MJ, Lapointe-Shaw L, Kwan JL, Weinerman AS, Rawal S, Tang T, Razak F, Verma AA Tags: CMAJ Source Type: research

Factors Predicting Misidentification of Acute Ischemic Stroke and Large Vessel Occlusion by Paramedics
The emergence of thrombectomy for large vessel occlusions has increased the importance of accurate prehospital identification and triage of acute ischemic stroke (AIS). Despite available clinical scores, prehospital identification is suboptimal. Our objective was to improve the sensitivity of prehospital AIS identification by combining dispatch information with paramedic impression. We performed a retrospective cohort review of emergency medical services and hospital records of all patients for whom a stroke alert was activated in 1 urban, academic emergency department from January 1, 2018, to December 31, 2019. Using admi...
Source: Critical Pathways in Cardiology - November 24, 2022 Category: Cardiology Tags: Original Study Source Type: research