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Condition: Ischemic Stroke
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Total 1297 results found since Jan 2013.

ISCHEMIC STROKE AND MAJOR BLEEDING WHILE ON DIRECT ORAL ANTICOAGULANTS IN NA ÏVE PATIENTS WITH ATRIAL FIBRILLATION: IMPACT OF RESUMPTION OR DISCONTINUATION OF ANTICOAGULANT TREATMENT. A population-based study.
We assessed the cumulative incidence of recurrent stroke, major bleeding and all-cause mortality associated with restarting antithrombotic treatment, in patients experiencing an anticoagulation-related event (stroke or major bleeding), occurred during anticoagulation therapy for AF.Methods and Results.We performed a retrospective population-based analysis on linked claims data of patients resident in the Veneto Region, treated with DOACs for AF and discharged (2013 −2020) from the hospital for stroke, intracranial haemorrhage (ICH), and major bleeding.
Source: International Journal of Cardiology - September 16, 2023 Category: Cardiology Authors: N. Gennaro, E. Ferroni, M. Zorzi, G. Denas, V. Pengo Source Type: research

Neutrophil-to-lymphocyte ratio at admission is a risk factor for in-hospital gastrointestinal bleeding in acute ischemic stroke patients after dual antiplatelet therapy: A case control study
Gastrointestinal bleeding is a clinically important complication in acute ischemic stroke patients after dual antiplatelet therapy. The present study was to explore the association between neutrophil-to-lymphocyte ratio (NLR) and in-hospital gastrointestinal  bleeding in acute ischemic stroke (AIS) patients who had received dual antiplatelet therapy.
Source: Journal of Stroke and Cerebrovascular Diseases - September 1, 2023 Category: Neurology Authors: Jiaming Huang, Foqiang Liao, Yeting Luo, Xu Shu Source Type: research

Comparative Analysis of the Results of Stroke Treatment With Multiple Administrations of Wharton's Jelly Mesenchymal Stem Cells-Derived HE-ATMP and Standard Conservative Treatment: Case Series Study
Cell Transplant. 2023 Jan-Dec;32:9636897231195145. doi: 10.1177/09636897231195145.ABSTRACTStroke remains still the leading cause of long-term disability worldwide. Although interventions such as early reperfusion, intravenous thrombolysis, and endovascular revascularization have shown neurological benefit in stroke patients, there is still lack of effective treatment enabling regeneration of nervous tissue after cerebral ischemic episodes. Cell therapy is an evolving opportunity for stroke survivors with residual neurological deficits. The purpose of this study was to evaluate safety and potential efficacy of multiple admi...
Source: Cell Transplantation - August 30, 2023 Category: Cytology Authors: Olga Milczarek Jakub Swad źba Patrycja Swad źba Anna Starowicz-Filip Roger M Krzy żewski Stanis ław Kwiatkowski Marcin Majka Source Type: research

The Role of the Low-Density Lipoprotein/High-Density Lipoprotein Cholesterol Ratio as an Atherogenic Risk Factor in Young Adults with Ischemic Stroke: A Case-Control Study
This study investigated the TC/HDL-C ratio and the LDL-C/HDL-C ratio, which may be more specific and common lipid parameters in young patients with ischemic stroke. This study aimed to demonstrate the sensitivity and specificity of TC/HDL-C and LDL-C/HDL-C ratios as atherogenic markers for young adult ischemic strokes. This trial was conducted as a retrospective case-control study. A total of 123 patients (patient group) and 86 healthy individuals (control group) aged 18-50 years were randomly selected from four different hospitals. Lipid parameters and TC/HDL-C and LDL-C/HDL-C ratios were compared between these two groups...
Source: Atherosclerosis - August 26, 2023 Category: Cardiology Authors: Sibel Ciplak Ahmet Adiguzel Yusuf Ziya Deniz Melike Aba Unal Ozturk Source Type: research

Short-term exposure to reduced specific-size ambient particulate matter increase the risk of cause-specific cardiovascular disease: A national-wide evidence from hospital admissions
This study provides robust evidence of short-term associations between PM1 concentrations and increased hospital admissions for all major cardiovascular diseases in China. Our findings suggest a greater short-term impact on cardiovascular risk from PM1 in comparison to PM2.5 and PM10.PMID:37611473 | DOI:10.1016/j.ecoenv.2023.115327
Source: Ecotoxicology and Environmental Safety - August 23, 2023 Category: Environmental Health Authors: Yaohua Tian Junhui Wu Yiqun Wu Mengying Wang Siyue Wang Ruotong Yang Xiaowen Wang Jiating Wang Huan Yu Dankang Li Tao Wu Jing Wei Yonghua Hu Source Type: research

Thrombolysis and thrombectomy for stroke in octogenarians and nonagenarians: A regional observational study
DISCUSSION: IVT and MT improve early neurological recovery and functional outcome at discharge of both octogenarians and nonagenarians in current practice. Despite a poorer outcome for nonagenarians than octogenarians, these reperfusion treatments should not be withheld on the basis of age only.PMID:37596186 | DOI:10.1016/j.neurol.2023.03.023
Source: Revue Neurologique - August 18, 2023 Category: Neurology Authors: M Michelard O Detante O Heck S Marcel W Vadot G Gavazzi J Papassin Source Type: research

Dysphagia after ischemic and hemorrhagic stroke: A propensity-matched 20-year analysis of the national inpatient sample
Post-stroke dysphagia (PSD) is a common and debilitating complication of acute stroke associated with increased mortality and morbidity.1,2 Globally, 12.2 million strokes occur every year and 1 in 4 adults over the age of 25 will have a stroke within their lifetime.3 Of these, 87% of strokes are considered ischemic strokes (AIS) and 10% are hemorrhagic (ICH), both of which are associated with dysphagia as an adverse event.4 Recent studies have found that the prevalence of long-term PSD ranges from 42-50% and was an independent risk factor for prolonged hospital stay, institutionalization after discharge, poorer functional ...
Source: Journal of Stroke and Cerebrovascular Diseases - August 4, 2023 Category: Neurology Authors: Vikram Vasan, Trevor A. Hardigan, Muhammad Ali, Margaret Downes, Alex Devarajan, Christina P. Rossitto, Braxton R. Schuldt, Ian C. Odland, Christopher P. Kellner, Johanna T. Fifi, J. Mocco, Shahram Majidi Source Type: research

Can Patent Foramen Ovales Cause Problems?
Discussion During fetal development, the heart primum and secundum septa grow and overlap leaving a small but important channel between the two atria. The foramen ovale is a flap valve moving blood from the right atrium into the left atrium directly and bypassing the high pressure pulmonary system. After birth and breathing air, the neonate’s lungs open up and the pulmonary vascular resistance decreases. The left atrium now has a relatively higher pressure than the right atria, and therefore pressure on the flap valve closes the foramen ovale. Usually within 6-12 months, the fusion of the primum and secundum of the f...
Source: PediatricEducation.org - July 24, 2023 Category: Pediatrics Authors: Pediatric Education Tags: Uncategorized Source Type: news

External validations of the ABCD2 score in prediction of stroke risk after transient ischemic attack. A Tunisian hospital-based cohort study
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Source: International Journal of Neuroscience - July 19, 2023 Category: Neuroscience Authors: Daoussi Nizar MSolli M. Amine Mouna Aissi Rafik Machraoui Sekma Adel Bel Haj Ali Khaoula Semir Blel Samia Younes Riadh Boukef Fay çal Henteti Semir Nouira Boubaker Hamdi Mahbouba Frih Source Type: research

China stroke surveillance report 2021
AbstractSince 2015, stroke has become the leading cause of death and disability in China, posing a significant threat to the health of its citizens as a major chronic non-communicable disease. According to the China Stroke High-risk Population Screening and Intervention Program, an estimated 17.8 million [95% confidence interval (CI) 17.6 –18.0 million] adults in China had experienced a stroke in 2020, with 3.4 million (95% CI 3.3–3.5 million) experiencing their first-ever stroke and another 2.3 million (95% CI 2.2–2.4 million) dying as a result. Additionally, approximately 12.5% (95% CI 12.4–12.5%) of stroke survi...
Source: Military Medical Research - July 19, 2023 Category: International Medicine & Public Health Source Type: research

The structured ambulatory post-stroke care program for outpatient aftercare in patients with ischaemic stroke in Germany (SANO): an open-label, cluster-randomised controlled trial
This study was registered with the German Clinical Trials Register, DRKS00015322.FINDINGS: Between Jan 1, 2019 and Dec 22, 2020, 36 clusters were assessed for eligibility, of which 30 were randomly assigned to the intervention group (n=15 clusters) or control group (n=15 clusters). No clusters dropped out of the study. 1203 (86%) of 1396 enrolled patients in the intervention group and 1283 (92%) of 1395 enrolled patients in the control group were included in the mITT population. The primary endpoint was confirmed in 64 (5·3%) of 1203 patients in the intervention group and 80 (6·2%) of 1283 patients in the control group (...
Source: Cancer Control - July 17, 2023 Category: Cancer & Oncology Authors: Christopher J Schwarzbach Felizitas Anna Eichner Viktoria R ücker Anna-Lena Hofmann Moritz Keller Heinrich J Audebert Stephan von Bandemer Stefan T Engelter Dieter Geis Klaus Gr öschel Karl Georg Haeusler Gerhard F Hamann Andreas Meisel Dirk Sander Mart Source Type: research

Acute coronary syndrome in very elderly patients —a real-world experience
AbstractVery elderly population constitutes an increasingly larger proportion of patients admitted for acute coronary syndromes (ACS). Notably, age represents both a proxy of frailty and an exclusion criterion in clinical randomized trials, which probably contributes to lack of data and undertreatment of real-world elderly patients. The aim of the study is to describe patterns of treatment and outcome of very elderly patients with ACS. All consecutive patients aged  ≥ 80 years old (yo) admitted between January 2017 and December 2019 with ACS were included. The primary endpoint was in-hospital occurrence of major adv...
Source: Heart and Vessels - July 15, 2023 Category: Cardiology Source Type: research