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Total 22 results found since Jan 2013.

The effect of butylphthalide on improving the neurological function of patients with acute anterior circulation cerebral infarction after mechanical thrombectomy
Medicine (Baltimore). 2023 Aug 25;102(34):e34616. doi: 10.1097/MD.0000000000034616.ABSTRACTButylphthalide can improve blood circulation in patients with acute cerebral infarction. Complement 3a receptor 1 (C3aR1) is involved in the regulation of innate immune response and pathogen monitoring, which is closely related to the pathophysiological processes of breast cancer, neurogenesis and lipid catabolism. Our study explored the therapeutic effect of butylphthalide on improving the neurological function of patients with acute anterior circulation cerebral infarction after mechanical thrombectomy, and evaluated the correlatio...
Source: Cancer Control - September 1, 2023 Category: Cancer & Oncology Authors: Xinghua Wang Xinchi Luan Zhigang Yang Source Type: research

Abbreviated MRI protocols effective for emergency applications
Abbreviated MRI protocols are effective for the diagnosis of emergent conditions...Read more on AuntMinnie.comRelated Reading: Short MRI with DWI improves accuracy in diagnosing breast cancer Abbreviated MRI can be alternative for breast cancer screening Short MRI plus CT identifies colorectal cancer liver metastases Rapid MRI for ED stroke evaluation cuts costs, hospital length of stay Could nonscanning factors affect abbreviated MRI workflow?
Source: AuntMinnie.com Headlines - May 15, 2023 Category: Radiology Source Type: news

Rapid MRI protocol leads to reduced image acquisition times
A rapid lumbar MRI protocol that uses 3D imaging and deep learning reconstructio...Read more on AuntMinnie.comRelated Reading: Reducing use of sedation for pediatric MRI cuts healthcare costs Ultrafast MRI shows promise in predicting DCIS upstaging Ultrafast DCE-MRI helps predict breast cancer treatment response Is abbreviated MRI useful for women at average breast cancer risk? Rapid MRI for ED stroke evaluation cuts costs, hospital length of stay
Source: AuntMinnie.com Headlines - January 6, 2023 Category: Radiology Source Type: news

Bringing WISDOM to Breast Cancer Care
Dr. Laura Esserman answers the door of her bright yellow Victorian home in San Francisco’s Ashbury neighborhood with a phone at her ear. She’s wrapping up one of several meetings that day with her research team at University of California, San Francisco, where she heads the Carol Franc Buck Breast Care Center. She motions me in and reseats herself at a makeshift home office desk in her living room, sandwiched between a grand piano and set of enormous windows overlooking her front yard’s flower garden. It’s her remote base of operations when she’s not seeing patients or operating at the hospita...
Source: TIME: Health - October 22, 2021 Category: Consumer Health News Authors: Alice Park Tags: Uncategorized Source Type: news

Cardiotoxicity of Use of Sequential Aromatase Inhibitors in Women With Breast Cancer
AbstractThe association between use of aromatase inhibitors (AIs) and cardiovascular outcomes is controversial. While some observational studies have assessed the cardiovascular safety of AIs as upfront treatments, their cardiotoxicity as sequential treatments with tamoxifen remains unknown. Thus, we conducted a population-based cohort study using data from the United Kingdom Clinical Practice Research Datalink linked to the Hospital Episode Statistics and Office for National Statistics databases. We employed a prevalent new-user design to propensity-score match, in a 1:2 ratio, patients switching from tamoxifen to AIs wit...
Source: American Journal of Epidemiology - April 27, 2020 Category: Epidemiology Source Type: research

Cardiotoxicity of Sequential Aromatase Inhibitors Use in Women with Breast Cancer.
Abstract The association between aromatase inhibitors and cardiovascular outcomes is controversial. While some observational studies have assessed their cardiovascular safety as up-front treatments, their cardiotoxic effects as sequential treatments with tamoxifen remains unknown. Thus, we conducted a population-based cohort study using the United Kingdom Clinical Practice Research Datalink linked to the Hospital Episode Statistics and Office for National Statistics databases. A prevalent new-user design was used to propensity score match, in a 1:2 ratio, patients switching from tamoxifen to aromatase inhibitors t...
Source: Am J Epidemiol - April 26, 2020 Category: Epidemiology Authors: Khosrow-Khavar F, Bouganim N, Filion KB, Suissa S, Azoulay L Tags: Am J Epidemiol Source Type: research

A Genetic Variant of miR-34a Contributes to Susceptibility of Ischemic Stroke Among Chinese Population
This study was supported by National Natural Science Foundation of China (Nos. 81560552, 81260234), Natural Science Foundation of Guangxi Zhuang Autonomous Region (CN) (2017JJA180826), Innovation Project of Guangxi Graduate Education (CN) (201601009) and Key Laboratory Open Project Fund of Guangxi Zhuang Autonomous Region (CN) (kfkt20160064). Conflict of Interest Statement The authors declare that the research was conducted in the absence of any commercial or financial relationships that could be construed as a potential conflict of interest. Supplementary Material The Supplementary Material for this article can be fou...
Source: Frontiers in Physiology - April 23, 2019 Category: Physiology Source Type: research

6-Bromoindirubin-3 ′-Oxime (6BIO) Suppresses the mTOR Pathway, Promotes Autophagy, and Exerts Anti-aging Effects in Rodent Liver
In this study, we aimed to investigate the anti-aging effect, and molecular mechanism, of the novel anti-aging drug 6BIO on naturally aged mouse liver. Rapamycin, a well-known promising anti-aging drug that delays aging through mTOR-dependent autophagy (Zhou and Ye, 2018), was used as the positive control in the study. To our knowledge, this is the first study to demonstrate the effects of 6BIO treatment in models of natural aging. Our results indicated that 6BIO ameliorates the decline of liver function with age, including lipid metabolism disorder, and attenuates hepatocyte senescence in aged mice, as revealed by altera...
Source: Frontiers in Pharmacology - April 9, 2019 Category: Drugs & Pharmacology Source Type: research

Mind the Treatment Gap
getty images/ istock photoBy Vani S. Kulkarni and Raghav GaihaPHILADELPHIA AND NEW DELHI, Apr 14 2017 (IPS)Implementation of the Mental Healthcare Act will require a restructuring of health-care services The Mental Healthcare Bill, 2016, which was passed in the Lok Sabha on March 27, 2017, has been hailed as a momentous reform. According to the Bill, every person will have the right to access mental health care operated or funded by the government; good quality and affordable health care; equality of treatment and protection from inhuman practices; access to legal services; and right to complain against coercion and cruelt...
Source: IPS Inter Press Service - Health - April 14, 2017 Category: Global & Universal Authors: Vani Kulkarni and Raghav Gaiha Tags: Asia-Pacific Development & Aid Gender Gender Violence Headlines Health Human Rights Women's Health Source Type: news

Common diseases as determinants of menopausal age
STUDY QUESTION Can the diagnosis of common diseases before menopause influence age at natural menopause (ANM) onset? SUMMARY ANSWER Polycystic ovary syndrome (PCOS) and depression were observed to delay menopause. WHAT IS KNOWN ALREADY It has been observed that women who undergo early menopause experience a higher burden of health problems related to metabolic syndromes, heart disease and depression, but whether ANM can be influenced by common adult diseases has not been studied extensively. STUDY DESIGN, SIZE, DURATION All women attending mammography screening or clinical mammography at four hospitals in Sweden were in...
Source: Human Reproduction - November 16, 2016 Category: Reproduction Medicine Authors: Li, J., Eriksson, M., Czene, K., Hall, P., Rodriguez-Wallberg, K. A. Tags: Reproductive Epidemiology Source Type: research

Medication Review After a Fracture
Approximately 1 of every 2 women and 1 of every 4 men aged 50 years or older will experience a fracture in their remaining lifetime. In fact, in the United States, the annual number of osteoporotic fractures that occur exceeds the incidence of heart attack, stroke, and breast cancer combined. Morbidity and mortality is considerable following major osteoporotic fractures, particularly in individuals with hip fracture: 44% of individuals with a hip fracture are readmitted to the hospital, and 21% will die in the first year following the fracture. This readmission rate is nearly 2-fold greater than the readmission rate follow...
Source: JAMA Internal Medicine - August 22, 2016 Category: Internal Medicine Source Type: research

From Conference To Clinic: The Longest Yard On Nutrition
The contrast between science and clinical practice can be so stark that it is shocking. I just returned from Washington, D.C. and the International Conference on Nutrition in Medicine sponsored by the Physicians Committee for Responsible Medicine and the Georgetown University School of Medicine. The first patient I saw in my preventive cardiology clinic after returning from the conference described his 25 year struggle with heart disease including 2 separate bypass operations, numerous stents, and activity severely limited by angina chest pain. He could barely walk to the mailbox without taking a nitro tablet under his ton...
Source: Healthy Living - The Huffington Post - August 9, 2016 Category: Consumer Health News Source Type: news

Lasting Impact of an Ephemeral Organ: The Role of the Placenta in Fetal Programming
Recent advances in molecular and imaging technologies, “omics” fields, and data sciences are offering researchers an unprecedented look at the placenta, the master regulator of the fetal environment.© EPA/National Geographic Channel/Alamy Studies of infants conceived during the Dutch “Hunger Winter” provided some of the earliest clues that prenatal stress could affect health much later in life.© Nationaal Archief  © Evan Oto/Science Source In one study, the placental microbiome had a similar taxonomic profile as the oral microbiome, illustrated here by...
Source: EHP Research - July 1, 2016 Category: Environmental Health Authors: Web Admin Tags: Featured Focus News July 2016 Source Type: research

Cochrane announces funding support for 10 new Cochrane Reviews
The Cochrane Editorial Unit is pleased to announce the 10 successful titles from the second Cochrane Review Support Programme (CRSP) funding round.Delayed antibiotics for respiratory infections (Acute Respiratory Infections Group) Bisphosphonates and other bone agents for breast cancer (Breast Cancer Group)Psychological therapies for the treatment of mental disorders in low- and middle-income countries affected by humanitarian crises (Common Mental Disorders Group)Drug eluting stents versus bare metal stents for acute coronary syndrome (Heart Group)Withdrawal of antihypertensive drugs in older people (Hypertension Group)Ph...
Source: Cochrane News and Events - June 27, 2016 Category: Information Technology Authors: nowens at cochrane.org Source Type: news

EPMA-World Congress 2015
Table of contents A1 Predictive and prognostic biomarker panel for targeted application of radioembolisation improving individual outcomes in hepatocellular carcinoma Jella-Andrea Abraham, Olga Golubnitschaja A2 Integrated market access approach amplifying value of “Rx-CDx” Ildar Akhmetov A3 Disaster response: an opportunity to improve global healthcare Russell J. Andrews, Leonidas Quintana A4 USA PPPM: proscriptive, profligate, profiteering medicine-good for 1 % wealthy, not for 99 % unhealthy Russell J. Andrews A5 The role of ...
Source: EPMA Journal - May 8, 2016 Category: Global & Universal Source Type: research