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Infectious Disease: Outbreaks

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Total 348 results found since Jan 2013.

The potential role of microvascular pathology in the neurological manifestations of coronavirus infection
We present the hypothesis that pre-existing vascular damage (due to aging, cardiovascular disease, diabetes, hypertension or other conditions) facilitates infiltration of the virus into the central nervous system (CNS), increasing neuro-inflammation and the likelihood o f neurological symptoms. We also discuss the role of a neuroinflammatory cytokine profile in both blood–brain barrier dysfunction and macrovascular disease (e.g. ischemic stroke and thromboembolism). Future studies are needed to better understand the involvement of the microvasculature in coronavi rus neuropathology, and to test the diagnostic potential o...
Source: Fluids and Barriers of the CNS - September 9, 2020 Category: Neuroscience Source Type: research

IJERPH, Vol. 17, Pages 6688: Neurological Complications of COVID-19 and Possible Neuroinvasion Pathways: A Systematic Review
Gemignani The Coronavirus Disease 2019 (COVID-19) outbreak has shocked the whole world with its unexpected rapid spread. The virus responsible for the disease, the Severe Acute Respiratory Syndrome Coronavirus 2 (SARS-CoV-2), enters host cells by means of the envelope spike protein, which binds to angiotensin-converting enzyme 2 receptors. These receptors are highly expressed in heart, lungs, respiratory tract epithelium, endothelial cells and brain. Since an increasing body of significant evidence is highlighting a possible neuroinvasion related to SARS-CoV-2, a state of the art on the neurological complications is n...
Source: International Journal of Environmental Research and Public Health - September 13, 2020 Category: Environmental Health Authors: Graziella Orr ù Ciro Conversano Eleonora Malloggi Francesca Francesconi Rebecca Ciacchini Angelo Gemignani Tags: Review Source Type: research

Johnson & Johnson Reports 2020 Third-Quarter Results
New Brunswick, N.J. (October 13, 2020) – Johnson & Johnson (NYSE: JNJ) today announced results for third-quarter 2020. “Our third-quarter results reflect solid performance and positive trends across Johnson & Johnson, powered by better-than-expected procedure recovery in Medical Devices, growth in Consumer Health, and continued strength in Pharmaceuticals,” said Alex Gorsky, Chairman and Chief Executive Officer. “I am proud of the relentless passion and Credo-led commitment to patients and customers that our colleagues around the world continue to demonstrate as we boldly fight the COVID-19 pandemic. Our wo...
Source: Johnson and Johnson - October 13, 2020 Category: Pharmaceuticals Tags: Our Company Source Type: news

Neurosurgery in times of a pandemic: a survey of neurosurgical services during the COVID-19 outbreak in the Veneto region in Italy.
CONCLUSIONS: This multicenter study describes the effects of a COVID-19 outbreak on neurosurgical activities in a vast region in Italy. Remodulation of neurosurgical activities has resulted in a significant reduction of elective and emergency surgeries compared to previous years. Most likely this is a combined result of cancellation of elective and postponable surgeries, increase of conservative management, increase in social restrictions, and in patients' fear of accessing hospitals. Curiously, only endovascular procedures for AIS have increased, possibly due to reduced physical activity or increased thrombosis in SARS-Co...
Source: Neurosurgical Focus - December 1, 2020 Category: Neurosurgery Authors: Raneri F, Rustemi O, Zambon G, Del Moro G, Magrini S, Ceccaroni Y, Basso E, Volpin F, Cappelletti M, Lardani J, Ferraresi S, Guida F, Chioffi F, Pinna G, Canova G, d'Avella D, Sala F, Volpin L Tags: Neurosurg Focus Source Type: research

Caring for acute coronary syndrome and other time-sensitive medical emergencies during the coronavirus disease 2019 pandemic in Northern Italy: report from a hub centre.
CONCLUSIONS: Re-organization of a hospital in order to adopt a hub-and-spoke model resulted feasible and allowed to face acute coronary syndrome and other time-sensitive medical emergencies timely and safely. PMID: 33258565 [PubMed - as supplied by publisher]
Source: Minerva Cardioangiologica - December 3, 2020 Category: Cardiology Tags: Minerva Cardioangiol Source Type: research

Spectrum of neuroimaging findings in COVID-19.
Abstract An outbreak of corona virus disease 2019 (COVID-19) began in China in December 2019, and rapidly spread to become a worldwide pandemic. Neurological complications encountered in hospitalized patients include acute arterial ischemic cerebrovascular stroke, cerebral venous thrombosis, critical illness-associated cerebral microbleeds, hypertensive hemorrhagic posterior reversible encephalopathy, meningoencephalitis/flare up of infections, flare up of multiple sclerosis, acute disseminated encephalomyelitis, cerebral hemodynamic/hypoxic changes such as watershed ischemic changes and hypoxic ischemic encephalo...
Source: The British Journal of Radiology - December 13, 2020 Category: Radiology Authors: El Beltagi AH, Vattoth S, Abdelhady M, Ahmed I, Paksoy Y, Abou Kamar M, Alsoub H, Almaslamani M, Alkhal AL, Own A, Elsotouhy A Tags: Br J Radiol Source Type: research

Significant reduction in the visits to the emergency room department during the COVID-19 pandemic in a tertiary hospital in Greece: Indirect victims of the pandemic?
COVID-19 pandemic caused a major crisis, affecting and straining health care systems, including some very advanced ones. The pandemic may have also indirectly affected access to health care for patients with other conditions, not related to COVID-19, even in countries not overwhelmed by an outbreak. We analyzed and compared visits to the emergency room (ER) department during the same calendar period of 2019 and 2020 (from March 1 to March 31 of each year) in our hospital, a medium size, tertiary center, located in the center of Athens, which is not a referral center for COVID-19. Total ER visits were reduced by 42.3%...
Source: Medicine - December 24, 2020 Category: Internal Medicine Tags: Research Article: Observational Study Source Type: research

What to know about hypertension: Left undetected can be fatal
In the midst of the outbreak and concerns over Covid-19, another condition that afflicts nearly half of all Americans has come into sharp focus: hypertension. Also known as high blood pressure, hypertension results when the long-term force of blood movement against your artery walls has become too high — so high, it can cause heart disease, kidney disease, stroke, and other potentially fatal heart health problems, especially if left undetected and untreated over time. It’s an increasingly common…
Source: bizjournals.com Health Care:Physician Practices headlines - January 11, 2021 Category: American Health Authors: TriHealth Source Type: news

The role of telemedicine in acute stroke treatment in times of pandemic
Purpose of review The coronavirus disease 2019 (COVID-19) pandemic challenges many healthcare systems. This review provides an overview of the advantages of telemedicine during times of pandemic and the changes that have followed the outbreak of the COVID-19 disease. Recent findings Telemedicine has been utilized during infectious outbreaks for many years. COVID-19 has induced a variety of changes in laws (i.e. data privacy protection) and reimbursement procedures to accelerate new setups of telemedicine. Existing networks provide novel data about teleactivation resulting from social restrictions during the nadi...
Source: Current Opinion in Neurology - January 21, 2021 Category: Neurology Tags: CEREBROVASCULAR DISEASE: Edited by Valeria Caso Source Type: research

Neurological symptoms, manifestations, and complications associated with severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) and coronavirus disease 19 (COVID-19)
AbstractSevere acute respiratory syndrome coronavirus 2 (SARS-CoV-2), a novel coronavirus, is responsible for the outbreak of coronavirus disease 19 (COVID-19) and was first identified in Wuhan, China in December 2019. It is evident that the COVID-19 pandemic has become a challenging world issue. Although most COVID-19 patients primarily develop respiratory symptoms, an increasing number of neurological symptoms and manifestations associated with COVID-19 have been observed. In this narrative review, we elaborate on proposed neurotropic mechanisms and various neurological symptoms, manifestations, and complications of COVI...
Source: Journal of Neurology - January 23, 2021 Category: Neurology Source Type: research

Potential mechanisms of cerebrovascular diseases in COVID-19 patients
AbstractSince the outbreak of coronavirus disease 2019 (COVID-19) in 2019, it is gaining worldwide attention at the moment. Apart from respiratory manifestations, neurological dysfunction in COVID-19 patients, especially the occurrence of cerebrovascular diseases (CVD), has been intensively investigated. In this review, the effects of COVID-19 infection on CVD were summarized as follows: (I) angiotensin-converting enzyme 2 (ACE2) may be involved in the attack on vascular endothelial cells by severe acute respiratory syndrome coronavirus-2 (SARS-CoV-2), leading to endothelial damage and increased subintimal inflammation, wh...
Source: Journal of NeuroVirology - February 3, 2021 Category: Neurology Source Type: research

Neurological associations of SARS-CoV-2 infection: A Systematic Review.
Abstract BACKGROUND: The current ongoing COVID-19 pandemic has compelled us to scrutinize major outbreaks in the past two decades, severe acute respiratory syndrome (SARS), in 2002, and Middle East respiratory syndrome (MERS), in 2012. We aimed to assess the associated neurological manifestations with SARS CoV-2 infection. METHODS: In this systematic review, a search was carried out by key-electronic databases, controlled vocabulary, and indexing of trials to evaluate the available pertinent studies which included both medical subject headings (MeSH) and advance electronic databases comprising of PubMed, Emba...
Source: CNS and Neurological Disorders Drug Targets - February 16, 2021 Category: Drugs & Pharmacology Authors: Javed A Tags: CNS Neurol Disord Drug Targets Source Type: research

Neurological associations of SARS-CoV-2 infection: A Systematic Review
CNS Neurol Disord Drug Targets. 2021 Feb 16. doi: 10.2174/1871527320666210216121211. Online ahead of print.ABSTRACTBACKGROUND: The current ongoing COVID-19 pandemic has compelled us to scrutinize major outbreaks in the past two decades, severe acute respiratory syndrome (SARS), in 2002, and Middle East respiratory syndrome (MERS), in 2012. We aimed to assess the associated neurological manifestations with SARS CoV-2 infection.METHODS: In this systematic review, a search was carried out by key-electronic databases, controlled vocabulary, and indexing of trials to evaluate the available pertinent studies which included both ...
Source: CNS and Neurological Disorders Drug Targets - February 17, 2021 Category: Drugs & Pharmacology Authors: Amaan Javed Source Type: research

COVID-19 Exposed the Faults in America ’s Elder Care System. This Is Our Best Shot to Fix Them
For the American public, one of the first signs of the COVID-19 pandemic to come was a tragedy at a nursing home near Seattle. On Feb. 29, 2020, officials from the U.S. Centers for Disease Control and Prevention (CDC) and Washington State announced the U.S. had its first outbreak of the novel coronavirus. Three people in the area had tested positive the day before; two of them were associated with Life Care Center of Kirkland, and officials expected more to follow soon. When asked what steps the nursing home could take to control the spread, Dr. Jeff Duchin, health officer for Seattle and King County, said he was working w...
Source: TIME: Health - June 15, 2021 Category: Consumer Health News Authors: Abigail Abrams Tags: Uncategorized Aging COVID-19 feature franchise Magazine TIME for Health Source Type: news

For HIV/AIDS Survivors, COVID-19 Reawakened Old Trauma —And Renewed Calls for Change
Forty years ago this month, the U.S. Centers for Disease Control and Prevention’s Morbidity and Mortality Weekly Report noted a rare lung infection among five otherwise healthy gay men in Los Angeles, Calif. Though they didn’t know it at the time, the scientists had written about what would turn out to be one of the historical moments that launched the Acquired Immunodeficiency Syndrome (AIDS) epidemic. Since then, HIV/AIDS has killed an estimated 35 million people, including 534,000 people in the U.S. from 1990 to 2018 alone, according to UNAIDS, making it one of the deadliest epidemics in modern history. Over...
Source: TIME: Health - June 17, 2021 Category: Consumer Health News Authors: Tara Law Tags: Uncategorized COVID-19 Source Type: news