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Infectious Disease: Syphilis

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Total 57 results found since Jan 2013.

Locked-in Syndrome Due to Meningovascular Syphilis: A Case Report and Literature Review
Intern Med. 2021 Oct 19. doi: 10.2169/internalmedicine.8269-21. Online ahead of print.ABSTRACTWe herein report a 46-year-old man presenting with locked-in syndrome secondary to meningovascular syphilis. Brain magnetic resonance imaging (MRI) demonstrated multiple acute infarctions in the left ventromedial pons, right basis pontis, and left basal ganglia. His locked-in syndrome was hypothesized to have been caused by thrombosis of the small paramedian branches of the basilar artery due to syphilitic arteritis. This is a unique case of bilateral ventromedial pontine infarction caused by meningovascular syphilis that presente...
Source: Internal Medicine - October 21, 2021 Category: Internal Medicine Authors: Yuki Yokota Masaki Ishihara Satoko Ninomiya Kazutaka Mitsuke Satoshi Kamei Hideto Nakajima Source Type: research

The associations of increased cerebral small vessel disease with cognitive impairment in neurosyphilis presenting with ischemic stroke
ConclusionsCerebral small vessel disease loads in neurosyphilis patients presenting with ischemic stroke are independently associated with acute cognitive impairment and have a prospective value for post-stroke cognitive outcomes.
Source: Brain and Behavior - May 17, 2021 Category: Neurology Authors: Lei Xiang, Tao Zhang, Biao Zhang, Chao Zhang, Shuping Hou, Wei Yue Tags: ORIGINAL RESEARCH Source Type: research

The relationship of syphilis to small vessel stroke in the absence of neurosyphilis: real or imaginary?
Source: Arquivos de Neuro-Psiquiatria - March 19, 2021 Category: Neurology Source Type: research

Small vessel occlusion and syphilis in patients with first-ever ischemic stroke
Conclusion: The current study showed that the frequency of positive syphilis serological test was higher in patients with first-ever ischemic stroke and SVD as the potential causal mechanism. This finding could be related to the endothelial dysfunction occurring in syphilis.RESUMO Introdu ção: A sífilis é uma doença endêmica, especialmente em países de baixa e média renda, com acometimento vascular descrito em grandes vasos (aortite), porém nenhuma relação clara foi reconhecida em paciente com acidente vascular cerebral, exceto para aqueles com sífilis meningovascular. O bjetivos: Investigar a relação entre h...
Source: Arquivos de Neuro-Psiquiatria - March 19, 2021 Category: Neurology Source Type: research

How Common are Aortic Aneurysms?
Discussion Aortic root dilatation or thoracic aortic aneurysm occurs in 6:100,000 individuals > 50 years of age. It is due to aging, hypertension, hypercholesterolemia, and smoking. Tertiary syphilis was a cause in the preantibiotic era. Pediatric aneurysms are very uncommon but the exact prevalence is different due to the various causes. Aneurysms are due to genetic disorders, congenital anomalies or post-surgical repair. In pediatric patients with sudden cardiac deaths, 5.4% are due to ruptured thoracic aortic aneurysms. Learning Point Some causes of pediatric aneurysms include: Familial thoracic aneurysm and dissect...
Source: PediatricEducation.org - February 22, 2021 Category: Pediatrics Authors: Pediatric Education Tags: Uncategorized Source Type: news

Positive syphilis serology contributes to intracranial stenosis in ischemic stroke patients
ConclusionsSyphilis infection, especially when less well controlled, may play an important role in intracranial stenosis of ischemic stroke patients.
Source: Brain and Behavior - October 21, 2020 Category: Neurology Authors: Lei Xiang, Tao Zhang, Biao Zhang, Chao Zhang, Wanzhen Cui, Wei Yue Tags: ORIGINAL RESEARCH Source Type: research

Intracranial calcifications in childhood: Part 2
This article is the second of a two-part series on intracranial calcification in childhood. In Part 1, the authors discussed the main differences between physiological and pathological intracranial calcification. They also outlined histological intracranial calcification characteristics and how these can be detected across different neuroimaging modalities. Part 1 emphasized the importance of age at presentation and intracranial calcification location and proposed a comprehensive neuroimaging approach toward the differential diagnosis of the causes of intracranial calcification. Pathological intracranial calcification can ...
Source: Pediatric Radiology - July 7, 2020 Category: Radiology Source Type: research

Frequency of Screening and Prevalence of Neurosyphilis in Stroke Population
Conclusion: Positive syphilis serology is frequent in patients with acute stroke/TIA in our region. Acute post-stroke CSF abnormalities make the diagnosis of NS difficult in the context of CSF VDRL negative.Cerebrovasc Dis
Source: Cerebrovascular Diseases - June 22, 2020 Category: Neurology Source Type: research

Infections causing stroke or stroke-like syndromes
ConclusionsStroke or stroke-like syndrome of infectious origin can be observed in an important proportion of case presenting with sensory-motor deficit of unknown origin; their accurate diagnosis has a considerable impact in terms of treatment choices and outcome.
Source: Infection - March 31, 2020 Category: Infectious Diseases Source Type: research

En mann i 40- årene med akutt innsettende talevansker og ensidig lammelse.
En mann i 40-årene med akutt innsettende talevansker og ensidig lammelse. Tidsskr Nor Laegeforen. 2019 Dec 10;139(18): Authors: Jahr SH, Myro AZ, Vegge K, Campbell P Abstract BACKGROUND: Stroke has several causes and the diagnostic investigation can be challenging. Neurosyphilis occurs when Treponema pallidum infects the central nervous system, and is a rare cause of stroke. CASE PRESENTATION: A man in in his late forties with diabetes mellitus and overweight presented with headache, speech impairment and right-sided stroke symptoms. He also had cognitive impairment and psychiatric symptoms. He ...
Source: Tidsskrift for den Norske Laegeforening - December 9, 2019 Category: General Medicine Authors: Jahr SH, Myro AZ, Vegge K, Campbell P Tags: Tidsskr Nor Laegeforen Source Type: research

Infectious Etiologies of Stroke
Semin Neurol 2019; 39: 482-494 DOI: 10.1055/s-0039-1687915Central nervous system (CNS) infections are a frequently underappreciated potential etiology of cerebrovascular disease. Highlighted in this review are a selection of infectious agents that lead to cerebrovascular complications through various mechanisms including multifocal vasculopathy, focal infiltrative vasculitis and vasospasm, and direct vessel wall invasion and thrombus formation. Diagnosis of stroke due to underlying CNS infection requires a high index of clinical suspicion and careful consideration of neuroimaging, serum, and cerebrospinal fluid studies in ...
Source: Seminars in Neurology - September 17, 2019 Category: Neurology Authors: Shulman, Julie G. Cervantes-Arslanian, Anna M. Tags: Review Article Source Type: research

What Causes Facial Nerve Palsy?
Discussion Facial nerve palsy has been known for centuries, but in 1821 unilateral facial nerve paralysis was described by Sir Charles Bell. Bell’s palsy (BP) is a unilateral, acute facial paralysis that is clinically diagnosed after other etiologies have been excluded by appropriate history, physical examination and/or laboratory testing or imaging. Symptoms include abnormal movement of facial nerve. It can be associated with changes in facial sensation, hearing, taste or excessive tearing. The right and left sides are equally affected but bilateral BP is rare (0.3%). Paralysis can be complete or incomplete at prese...
Source: PediatricEducation.org - June 3, 2019 Category: Pediatrics Authors: pediatriceducationmin Tags: Uncategorized Source Type: news

Isolation of Antimicrobial Compounds From Cnestis ferruginea Vahl ex. DC (Connaraceae) Leaves Through Bioassay-Guided Fractionation
Conclusion In conclusion, aqueous extracts of C. ferruginea leaves showed antimicrobial activity due to the presence of hydroquinone and caffeic acid methyl ester. This supports its traditional use for infections and confirmed that the active molecules are water-soluble. Author Contributions KK, SP, LVP, and WL conceived and designed the experiments. SP, KK, M-RY, and J-GL performed the experiments. SP, LVP, WL, M-RY, J-GL, and Z-HJ analyzed the data. WL and Z-HJ contributed reagents, materials, and analysis tools. KK, SP, WL, M-RY, Z-HJ, and LVP contributed to the writing of the manuscript. All authors contributed to m...
Source: Frontiers in Microbiology - April 10, 2019 Category: Microbiology Source Type: research