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Infectious Disease: Ebola
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Life and death in the United States, in two maps
The latest news about preventable deaths in the United States has some encouraging data and one sobering statistic. On the good-news front, fewer people are dying prematurely from three of the five leading causes of death between 2010 and 2014: cancer, stroke and heart disease. But there was a significant increase in preventable deaths from […]Related:The Ebola outbreak may have been bigger than believed, with ‘invisible’ infectionThe ultimate Q&A about health care under a Trump presidencyTeamsters demand McKesson CEO return millions of dollars for role in opioid crisis
Source: Washington Post: To Your Health - November 17, 2016 Category: Consumer Health News Source Type: news
Global, regional, and national life expectancy, all-cause mortality, and cause-specific mortality for 249 causes of death, 1980 –2015: a systematic analysis for the Global Burden of Disease Study 2015
Publication date: 8–14 October 2016 Source:The Lancet, Volume 388, Issue 10053 Author(s): GBD 2015 Mortality and Causes of Death CollaboratorsHaidongWangMohsenNaghaviChristineAllenRyan MBarberZulfiqar ABhuttaAustinCarterDaniel CCaseyFiona JCharlsonAlan ZianChenMatthew MCoatesMeganCoggeshallLalitDandonaDaniel JDickerHolly EErskineAlize JFerrariChristinaFitzmauriceKyleForemanMohammad HForouzanfarMaya SFraserNancyFullmanPeter WGethingEllen MGoldbergNicholasGraetzJuanita AHaagsmaSimon IHayChantalHuynhCatherine OJohnsonNicholas JKassebaumYohannesKinfuXie RachelKulikoffMichaelKutzHmwe HKyuHeidi JLarsonJanniLeungXiaofengLiangS...
Source: The Lancet - October 6, 2016 Category: Journals (General) Source Type: research
Patty Duke's Death Announcement Is A Milestone For Sepsis Awareness
Oscar-winning actress Patty Duke, star of "The Patty Duke Show" and the Broadway play and film “The Miracle Worker,” died of sepsis from a ruptured intestine on Tuesday. Simple though it may seem, her death announcement is a major milestone for the sepsis awareness movement, said Thomas Heymann, executive director of the Sepsis Alliance. The more people are aware of this condition, Heymann said, the stronger their likelihood of saving their own lives or the lives of their loved ones. "The fact that they said Patty Duke’s cause of death was sepsis is relatively new," Heymann said. "It very often ...
Source: Science - The Huffington Post - March 30, 2016 Category: Science Source Type: news
PodMed: A Medical News Roundup From Johns Hopkins (with audio)
(MedPage Today) -- This week's topics include testosterone in older men, carotid procedures in those without symptoms, pioglitazone after a stroke, and managing Ebola in the U.S. and Europe
Source: MedPage Today Cardiovascular - February 20, 2016 Category: Cardiology Source Type: news
How Terrified Should We Be?
After every terrorist attack we go through a period of overwhelming fear that we will individually be the target of terrorism. Recently a man told me that he will avoid going to crowded areas of the city because he fears being killed by a terrorist. A woman fears flying because she fears the plane will be blown up by a terrorist. Years ago, after 9/11, a woman told me that she feared "Arab-looking men" in the subway. And, after 9/11, years ago, a family moved to Colorado from New York City because of their fear of terrorism. Fear pervaded the lives of many people and, once again, after the attack in San Bernardino, Califor...
Source: Healthy Living - The Huffington Post - December 23, 2015 Category: Consumer Health News Source Type: news
Red blood cell replacement, or nanobiotherapeutics with enhanced red blood cell functions?
Authors: Chang TM
Abstract
Why is this important? Under normal circumstances, donor blood is the best replacement for blood. However, there are exceptions: During natural epidemics (e.g., HIV, Ebola, etc.) or man-made epidemics (terrorism, war, etc.), there is a risk of donor blood being contaminated, and donors being disqualified because they have contracted disease. Unlike red blood cells (RBCs), blood substitutes can be sterilized to remove infective agents. Heart attack and stroke are usually caused by obstruction of arterial blood vessels. Unlike RBCs, which are particulate, blood substitutes are in the form o...
Source: Artificial Cells, Nanomedicine and Biotechnology - December 12, 2015 Category: Biotechnology Tags: Artif Cells Nanomed Biotechnol Source Type: research
Activated protein C: biased for translation
The homeostatic blood protease, activated protein C (APC), can function as (1) an antithrombotic on the basis of inactivation of clotting factors Va and VIIIa; (2) a cytoprotective on the basis of endothelial barrier stabilization and anti-inflammatory and antiapoptotic actions; and (3) a regenerative on the basis of stimulation of neurogenesis, angiogenesis, and wound healing. Pharmacologic therapies using recombinant human and murine APCs indicate that APC provides effective acute or chronic therapies for a strikingly diverse range of preclinical injury models. APC reduces the damage caused by the following: ischemia/rep...
Source: Blood - May 7, 2015 Category: Hematology Authors: Griffin, J. H., Zlokovic, B. V., Mosnier, L. O. Tags: Vascular Biology, Review Articles Source Type: research
Ebola Epidemic Takes a Toll on Sierra Leone's Surgeons
This article originally appeared here on ScientificAmerican.com.
Thaim Kamara is 60 years old and would like to retire this year. But he is one of only eight remaining surgeons in Sierra Leone, a west African country of about 6 million people. Kamara lost two friends to Ebola in 2014 -- Martin Salia and Thomas Rogers, fellow surgeons at Connaught Hospital in the capital, Freetown. In light of the dire circumstances, Kamara has postponed his plan to retire.
Although the rate of new Ebola infections in Sierra Leone, along with neighboring countries Guinea and Liberia, is finally falling, more than 800 health care personnel...
Source: Healthy Living - The Huffington Post - February 7, 2015 Category: Consumer Health News Source Type: news
Could pharmacological curtailment of the RhoA/Rho-kinase pathway reverse the endothelial barrier dysfunction associated with Ebola virus infection?
Publication date: February 2015 Source:Antiviral Research, Volume 114 Author(s): Shahram Eisa-Beygi , Xiao-Yan Wen Activation of the RhoA/Rho-kinase (ROCK) pathway induces endothelial barrier dysfunction and increased vascular permeability, which is a hallmark of various life-threatening vascular pathologies. Therapeutic approaches aimed at inhibiting the RhoA/ROCK pathway have proven effective in the attenuation of vascular leakage observed in animal models of endotoxin-induced lung injury/sepsis, edema, autoimmune disorders, and stroke. These findings suggest that treatments targeting the ROCK pathway might be of benef...
Source: Antiviral Therapy - January 2, 2015 Category: Virology Source Type: research
CDC's Mission: Protecting the Health of Americans
There is no doubt Ebola will rank as the biggest public health story of 2014, both here in the United States and around the world: more people sickened by Ebola than ever before in history, more people dying, and more understanding of how the health of one nation affects the health of us all.
Today, more than 170 of CDC's top health professionals are in West Africa working to stop the current Ebola epidemic and leave behind stronger public health systems. Many hundreds more support their work at home.
Leaving behind better capacities to find, stop, and prevent health threats in affected countries will help prevent the ...
Source: Healthy Living - The Huffington Post - December 24, 2014 Category: Consumer Health News Source Type: news
Could pharmacological curtailment of the RhoA/Rho-kinase pathway reverse the endothelial barrier dysfunction associated with Ebola virus infection?
Abstract
Activation of the RhoA/Rho-kinase (ROCK) pathway induces endothelial barrier dysfunction and increased vascular permeability, which is a hallmark of various life-threatening vascular pathologies. Therapeutic approaches aimed at inhibiting the RhoA/ROCK pathway have proven effective in the attenuation of vascular leakage observed in animal models of endotoxin-induced lung injury/sepsis, edema, autoimmune disorders, and stroke. These findings suggest that treatments targeting the ROCK pathway might be of benefit in the management of the Ebola virus disease (EVD), which is characterized by severe vascular le...
Source: Antiviral Research - December 13, 2014 Category: Virology Authors: Eisa-Beygi S, Wen X Tags: Antiviral Res Source Type: research
PodMed: A Medical News Roundup From Johns Hopkins (with audio)
(MedPage Today) -- This week's topics include best medication for initial diabetes therapy, Ebola update, lowering blood pressure after stroke, and an LDL variant and aortic valve disease.
Source: MedPage Today Cardiovascular - November 1, 2014 Category: Cardiology Source Type: news
Young, Healthy People Warned Not To Ignore Signs Of Atrial Fibrillation
BOSTON (CBS) – Heart problems are big problems for Americans, but if you think they only affect the elderly, think again. Younger and otherwise healthy people are having heart problems, too, even if they’re in great shape.
Mark Marshall is only 51. The competitive wrestler was out for a training run when suddenly he felt a flutter in his chest and his vision blurred. “In my mind I’m thinking, you must be dehydrated. I had no idea I was in afib,” he remembers.
But he was, even though Mark had none of the risk factors for atrial fibrillation like high blood pressure, high cholesterol and old ag...
Source: WBZ-TV - Breaking News, Weather and Sports for Boston, Worcester and New Hampshire - October 1, 2014 Category: Consumer Health News Authors: deanreddington Tags: Health Local News Seen On WBZ-TV Syndicated Local Watch Listen AFib Atrial Fibrillation Mallika Marshall Mark Marshall Source Type: news
The Week Ahead: Stroke in Kids, Prayer in Practice
(MedPage Today) -- Another installment in the ?I, Intern ?? series, a look at a formal spiritual protocol, teen pregnancy, and the latest on Ebola -- all coming this week from MedPage Today.
Source: MedPage Today Cardiovascular - August 18, 2014 Category: Cardiology Source Type: news
Hamsters, Higgs and historians - blogs roundup
Posts on our network included a look at the race to put humans on Mars, whether closing stroke units can improve survival rates, and some scaremongering facts about Ebola Continue reading...
Source: Guardian Unlimited Science - August 8, 2014 Category: Science Authors: Pete Etchells Tags: Science Source Type: news
