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Condition: Heart Attack
Infectious Disease: Epidemics

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Total 79 results found since Jan 2013.

Hypertension: Do Inflammation and Immunity Hold the Key to Solving this Epidemic?
Circ Res. 2021 Apr 2;128(7):908-933. doi: 10.1161/CIRCRESAHA.121.318052. Epub 2021 Apr 1.ABSTRACTElevated cardiovascular risk including stroke, heart failure, and heart attack is present even after normalization of blood pressure in patients with hypertension. Underlying immune cell activation is a likely culprit. Although immune cells are important for protection against invading pathogens, their chronic overactivation may lead to tissue damage and high blood pressure. Triggers that may initiate immune activation include viral infections, autoimmunity, and lifestyle factors such as excess dietary salt. These conditions ac...
Source: Circulation Research - April 1, 2021 Category: Cardiology Authors: Meena S Madhur Fernando Elijovich Matthew R Alexander Ashley Pitzer Jeanne Ishimwe Justin P Van Beusecum David M Patrick Charles D Smart Thomas R Kleyman Justin Kingery Robert N Peck Cheryl L Laffer Annet Kirabo Source Type: research

Obesity and Aging: Molecular Mechanisms and Therapeutic Approaches.
Abstract The epidemic of obesity is a major challenge for health policymakers due to its far-reaching effects on population health and potentially overwhelming financial burden on healthcare systems. Obesity is associated with an increased risk of developing acute and chronic diseases, including hypertension, stroke, myocardial infarction, cardiovascular disease, diabetes, and cancer. Interestingly, the metabolic dysregulation associated with obesity is similar to that observed in normal aging, and substantial evidence suggests the potential of obesity to accelerate aging. Therefore, understanding the mechanism of...
Source: Ageing Research Reviews - February 5, 2021 Category: Genetics & Stem Cells Authors: Santos AL, Sinha S Tags: Ageing Res Rev Source Type: research

Overdose Receiving Centers - An Idea Whose Time Has Come?
Authors: Hern HG, Goldstein D, Tzvieli O, Mercer M, Sporer K, Herring AA Abstract Drug overdose deaths have been the leading cause of accidental death in the United States with two thirds involving opioids. Strong evidence supports the efficacy of medications for addiction treatment such as buprenorphine and harm reduction strategies such as naloxone distribution. While emergency medical service (EMS) systems have defined specialty centers for the treatment of many significant life threatening disease (trauma, stroke, myocardial infarction) implementation of opioid use disorder systems of care that integrate EMS ar...
Source: Prehospital Emergency Care - January 30, 2021 Category: Endocrinology Tags: Prehosp Emerg Care Source Type: research

Less Myocardial Infarction and Stroke Hospitalizations During Middle East Respiratory Syndrome Coronavirus Epidemic in Korea
Viral infections are known to impact coronary disease, and acute myocardial infarction (AMI) may be triggered by the inflammatory cytokine response to infection.1,2 Cytokines promote local inflammation in atherosclerotic plaques within the coronary artery, which can lead to plaque destabilization, rupture, and eventually AMI development. Psychological adversity, depression, stress at home or work, social isolation and loneliness are also known factors contributing to acute vascular event.3 Recent outbreaks of coronavirus (CoV), including severe acute respiratory syndrome (SARS), and Middle East respiratory syndrome (MERS) ...
Source: The American Journal of Cardiology - July 2, 2020 Category: Cardiology Authors: Cai De Jin, Moo Hyun Kim, Kwang Min Lee, Jong Sung Park, Dong Sik Jung, Sung-Cheol Yun, Victor Serebruany Source Type: research

Doctors Warn Not To Ignore Signs Of Heart Attack, Stroke Amid Coronavirus Pandemic
BOSTON (CBS) – Boston health care providers are pleading with the public to seek medical treatment if they are suffering from illnesses unrelated to the coronavirus. “Because when it comes to your health, time can be the difference between life and death,” Brigham Health trauma surgeon Dr. Stephanie Nitzschke says in a new public service announcement released by area hospitals. Doctors say they have seen a dramatic decrease in the number of stroke, heart attack, and other patients who would normally fill emergency departments. “My center and a number of others in Boston estimated a reduction of about 25 perc...
Source: WBZ-TV - Breaking News, Weather and Sports for Boston, Worcester and New Hampshire - April 22, 2020 Category: Consumer Health News Authors: Health – CBS Boston Tags: Boston News Health Syndicated CBSN Boston Syndicated Local Coronavirus Louisa Moller Source Type: news

Don ’t be Caught Half-dressed When Working with Radiation
AbstractA typical 2-piece personal protective equipment apron covers only half the body. However, with radiation exposure there is evidence of the following: (1) Left-sided head exposure estimates equal to 100,000 chest X-rays over a 20-year career, (2) direct linear relationship between stroke and concentration of dose, (3) increases in ischemic heart disease and myocardial infarction, (4) accelerated aging processes, and (5) increased double-stranded DNA breaks in circulating lymphocytes when lower legs are exposed. Every exposure to ionizing radiation involves a health risk that accumulates. Interventionalists are treat...
Source: CardioVascular and Interventional Radiology - December 15, 2019 Category: Radiology Source Type: research

High blood pressure: Avoid eating this popular winter food to lower your reading
HIGH blood pressure is extremely common and a worldwide epidemic. If a person has high blood pressure and don ’t treat the condition accordingly it could lead to serious health complications such as heart attack or stroke. What a person eats is crucial for those with the condition or those looking to prevent it - certain foods can either help or hinder high blood pressure. Eating a certain food that's pop ular in winter could increase a person's risk.
Source: Daily Express - Health - November 20, 2019 Category: Consumer Health News Source Type: news

The role of nutraceuticals in prevention and treatment of hypertension: An updated review of the literature
Publication date: Available online 7 November 2019Source: Food Research InternationalAuthor(s): Samad Ghaffari, Neda RoshanravanAbstractHypertension (HTN) is a worldwide epidemic in both developed and developing countries. It is one of the leading causes of major health problems such as cardiovascular disease, stroke, and heart attack. In recent years, several studies have reported associations between specific dietary ingredients and improving HTN. Nutraceuticals are natural food components with pharmacological properties. Reports suggest that functional foods and nutraceutical ingredients might support patients to obtain...
Source: Food Research International - November 8, 2019 Category: Food Science Source Type: research

Abiomed Hits TCT 2019 Running with Compelling Data and New Approval
Abiomed certainly brought its A-game to the 31st annual Transcatheter Cardiovascular Therapeutics (TCT) conference- being held now and throughout the weekend. The Danvers, MA-based company came armed with the news of a newly-approved device and data from its PROTECT III trial, an ongoing prospective, single-arm FDA post-market study for the Impella 2.5 and Impella CP in high-risk PCI. Abiomed, which was named one of the top 25 M&A targets in medtech, said an interim analysis of 898 patients from the PROTECT III trial demonstrated a reduction in the primary endpoint of death, stroke, myocardial infarction, and repeat pr...
Source: MDDI - September 26, 2019 Category: Medical Devices Authors: Omar Ford Tags: Cardiovascular Source Type: news

A Brief Review of Cardiovascular Diseases, Associated Risk Factors and Current Treatment Regimes.
Abstract Cardiovascular diseases (CVDs) are the leading cause of premature death and disability in humans and their incidence is on the rise globally. Given their substantial contribution towards the escalating costs of health care, they also generate a high socio-economic burden in the general population. The underlying pathogenesis and progression associated with nearly all CVDs is predominantly of atherosclerotic origin that leads to the development of coronary artery disease, cerebrovascular disease, venous thromboembolism and, peripheral vascular disease, subsequently causing myocardial infarction, cardiac ar...
Source: Current Pharmaceutical Design - September 24, 2019 Category: Drugs & Pharmacology Authors: Flora GD, Nayak MK Tags: Curr Pharm Des Source Type: research

Impaired Activity of Ryanodine Receptors Contributes to Calcium Mishandling in Cardiomyocytes of Metabolic Syndrome Rats
Conclusion Principal findings of this work are that abnormal Ca2+ transient amplitude, contractile dysfunction; and impaired relaxation of MetS cardiomyocytes underlies intrinsic dysfunctional RyR2 and SERCA pump. Abnormal activity of RyRs was evidenced by its decreased ability to bind [3H]-ryanodine. Although the MetS condition does not modify RyR2 protein expression, its phosphorylation at Ser2814 is decreased, which impairs its capacity for activation during ECC. The dysfunctional RyRs, together with a decreased activity of SERCA pump due to decreased Thr17-PLN phosphorylation suggest a downregulation of CaMKII in MetS...
Source: Frontiers in Physiology - April 29, 2019 Category: Physiology Source Type: research

Diet Beverages Linked To Increased Stroke Risk & Heart Attacks
This study, as well as other research on the connection between diet beverages and vascular disease, is observational and cannot show cause and effect. That’s a major limitation, researchers say, as it’s impossible to determine whether the association is due to a specific artificial sweetener, a type of beverage or another hidden health issue. “Postmenopausal women tend to have higher risk for vascular disease because they are lacking the protective effects of natural hormones,” North Carolina cardiologist Dr. Kevin Campbell said, which could contribute to increased risk for heart disease and stroke...
Source: WBZ-TV - Breaking News, Weather and Sports for Boston, Worcester and New Hampshire - February 14, 2019 Category: Consumer Health News Authors: Health – CBS Boston Tags: Health News CNN Heart Attack Stroke Source Type: news