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Infectious Disease: Dengue Fever

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The authors respond to "Is there a real increased risk of stroke in patients with dengue fever?"
PMID: 30087132 [PubMed - in process]
Source: cmaj - August 7, 2018 Category: General Medicine Authors: Li HM Tags: CMAJ Source Type: research

Is there a real increased risk of stroke in patients with dengue fever?
PMID: 30087131 [PubMed - in process]
Source: cmaj - August 7, 2018 Category: General Medicine Authors: Joob B, Wiwanitkit V Tags: CMAJ Source Type: research

Diabetic patients suffering dengue are at risk for development of dengue shock syndrome/severe dengue: emphasizing the impacts of co-existing comorbidity(ies) and glycemic control on dengue severity
ConclusionsThese data could help narrow down the number of targets in the triage for risky DM2 dengue patients to those with suboptimal glycemic control and co-existing comorbidity(ies).
Source: Journal of Microbiology, Immunology and Infection - July 10, 2018 Category: Microbiology Source Type: research

Cerebral vasculitis and lateral rectus palsy – two rare central nervous system complications of dengue fever: two case reports and review of the literature
ConclusionsCentral nervous system vasculitis due to dengue infection is a very rare phenomenon, and to the best of our knowledge, only one case of central nervous system vasculitis has been reported to date, in a patient of pediatric age. Cranial nerve palsy related to dengue infection is also rare, and only a few cases of isolated abducens nerve palsy have been reported to date. The two cases described in this report illustrate the rare but important central nervous system manifestations of dengue fever and support the fact that the central nervous system is one of the important systems that can be affected in patients with dengue infection.
Source: Journal of Medical Case Reports - April 19, 2018 Category: General Medicine Source Type: research

Risk of stroke in patients with dengue fever: a population-based cohort study.
Authors: Li HM, Huang YK, Su YC, Kao CH Abstract BACKGROUND: Stroke is a severe neurologic complication of dengue fever, described in only a few case reports. The incidence and risk factors for stroke in patients with dengue remain unclear. We conducted a population-based retrospective cohort study to investigate the risk of stroke in patients with dengue. METHODS: Using data from the Taiwan National Health Insurance Research Database, we included a total of 13 787 patients with dengue newly diagnosed between 2000 and 2012. The control cohort consisted of patients who did not have dengue, matched 1:1 by demogra...
Source: Canadian Medical Association Journal - March 14, 2018 Category: General Medicine Tags: CMAJ Source Type: research

Diabetic patients suffering dengue are at risk for development of dengue shock syndrome/severe dengue: emphasizing the impacts of co-existing comorbidity(ies) and glycemic control on dengue severity
Conclusions These data could help narrow down the number of targets in the triage for risky DM2 dengue patients to those with suboptimal glycemic control and co-existing comorbidity(ies).
Source: Journal of Microbiology, Immunology and Infection - February 1, 2018 Category: Microbiology Source Type: research

10 Global Health Issues to Watch in 2018
January 19, 2018It ’s notallbad news.When we set out to compile our annual list of global health issues to watch this year, it seemed like all bad news. And true, that ’s often what we deal with in global health—the problems that need tackling, the suffering we can help alleviate.But then stories and columns likethis one cheer us up. They remind us that no matter how complicated and frustrating our work may get, fighting back against poverty and inequality works.There are and always will be global health challenges to face. But there ’s boundless hope, too. And a field full of determined health workers and other hu...
Source: IntraHealth International - January 19, 2018 Category: International Medicine & Public Health Authors: mnathe Source Type: news

“An Uncommon Complication of Dengue”
We present here bilateral cerebellar bleed because of dengue virus infection.
Source: Journal of Stroke and Cerebrovascular Diseases - November 2, 2017 Category: Neurology Authors: Manan Mehta, Praveen Kumar Sharma, Ravindra Kumar Garg Tags: Case Studies Source Type: research

Stroke in a child with dengue encephalopathy
Sangeetha Yoganathan, Sniya Valsa Sudhakar, Leena Priyambada, Maya ThomasAnnals of Indian Academy of Neurology 2017 20(3):329-331
Source: Annals of Indian Academy of Neurology - August 10, 2017 Category: Neurology Authors: Sangeetha Yoganathan Sniya Valsa Sudhakar Leena Priyambada Maya Thomas Source Type: research

Cardio-haemodynamic assessment and venous lactate in severe dengue: Relationship with recurrent shock and respiratory distress
by Sophie Yacoub, Trieu Huynh Trung, Phung Khanh Lam, Vuong Huynh Ngoc Thien, Duong Ha Thi Hai, Tu Qui Phan, Oanh Pham Kieu Nguyet, Nguyen Than Ha Quyen, Cameron Paul Simmons, Christopher Broyd, Gavin Robert Screaton, Bridget Wills BackgroundDengue can cause plasma leakage that may lead to dengue shock syndrome (DSS). In approximately 30% of DSS cases, recurrent episodes of shock occur. These patients have a higher risk of fluid overload, respiratory distress and poor outcomes. We investigated the association of echocardiographically-derived cardiac function and intravascular volume parameters plus lactate levels, with the...
Source: PLoS Neglected Tropical Diseases - July 10, 2017 Category: Tropical Medicine Authors: Sophie Yacoub Source Type: research

Zika associated Guillain-Barre syndrome in the United States (P2.327)
Conclusions:Zika can induce GBS after a brief viral illness. Neuropathy can be a mixture of demyelinating and axonal. Dysautonomia may also be present including severe dysphagia, orthostatics and retention.Zika RNA has a short detection window in serum and CSF making a diagnosis time sensitive. Serological assays using IgM and IgG cross-react with other flaviviruses making them unable to differentiate between recent Zika exposure and cross reactivity with Dengue and Chikungunya. Our pt likely had prior exposure to Dengue, being from an endemic area. Prior Dengue exposure may possibly modulate the response to Zika via antib...
Source: Neurology - April 17, 2017 Category: Neurology Authors: Tantillo, G., Sclar, G., Vasa, C., Shin, S., Sivak, M. Tags: Zika, Chikungunya, West Nile Virus, and Other Viral Infections I Source Type: research

Behind the Headlines 2016 Quiz of the Year
In 2014, Behind the Headlines has covered more than 500 health stories that made it into the mainstream media. If you've been paying attention you should find this quiz easy and fun. Why not test your knowledge of 2014's health news with our month-by-month quiz? Answers are at the foot of the page (no peeking!).   In January 2016's health news... In a controversial study, monkeys were genetically engineered to develop what disorder? 1) Sex addiction 2) Bi-polar disorder 3) Autism In a similarly controversial study, what psychological condition was dismissed as a "myth" 1) Seasonal affective disorder...
Source: NHS News Feed - December 5, 2016 Category: Consumer Health News Tags: Special reports Source Type: news

Global, regional, and national life expectancy, all-cause mortality, and cause-specific mortality for 249 causes of death, 1980 –2015: a systematic analysis for the Global Burden of Disease Study 2015
Publication date: 8–14 October 2016 Source:The Lancet, Volume 388, Issue 10053 Author(s): GBD 2015 Mortality and Causes of Death CollaboratorsHaidongWangMohsenNaghaviChristineAllenRyan MBarberZulfiqar ABhuttaAustinCarterDaniel CCaseyFiona JCharlsonAlan ZianChenMatthew MCoatesMeganCoggeshallLalitDandonaDaniel JDickerHolly EErskineAlize JFerrariChristinaFitzmauriceKyleForemanMohammad HForouzanfarMaya SFraserNancyFullmanPeter WGethingEllen MGoldbergNicholasGraetzJuanita AHaagsmaSimon IHayChantalHuynhCatherine OJohnsonNicholas JKassebaumYohannesKinfuXie RachelKulikoffMichaelKutzHmwe HKyuHeidi JLarsonJanniLeungXiaofengLiangS...
Source: The Lancet - October 6, 2016 Category: Journals (General) Source Type: research

Urban climate versus global climate change—what makes the difference for dengue?
The expansion in the geographical distribution of vector‐borne diseases is a much emphasized consequence of climate change, as are the consequences of urbanization for diseases that are already endemic, which may be even more important for public health. In this paper, we focus on dengue, the most widespread urban vector‐borne disease. Largely urban with a tropical/subtropical distribution and vectored by a domesticated mosquito, Aedes aegypti, dengue poses a serious public health threat. Temperature plays a determinant role in dengue epidemic potential, affecting crucial parts of the mosquito and viral life cycles. Th...
Source: Annals of the New York Academy of Sciences - May 18, 2016 Category: Science Authors: Renaud Misslin, Olivier Telle, Eric Daudé, Alain Vaguet, Richard E. Paul Tags: Original Article Source Type: research