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Mr. M
Dr. Migliore I step off the subway, up the elevator, and up several flights of stairs. There’s a homeless man there who always uses the last stair of the lower staircase as a tray for his food. And by tray, I mean he sets his half-eaten rice burrito directly onto the step and picks around at it while I imagine the guacamole is mixing with Hep B and C. diff and MRSA. He looks up at me, I promise myself for the 100th time I’m going to start carrying cash or Kind bars or something; I give him my best sheepish face, and emerge at street level. I walk toward my hospital and pass a gentleman who sits on a ledge next to the ...
Source: The Hospitalist - December 1, 2022 Category: Hospital Management Authors: Lisa Casinger Tags: Essay Source Type: research

Serum Bilirubin Associated with Stroke Severity and Prognosis: Preliminary Findings on Liver Function after Acute Ischemic Stroke
CONCLUSION: High Tbil and Dbil level within 48 hours of symptom onset could be an independent marker of severity of stroke on admission and discharge for all AIS patients. For patient with mild stroke, elevation of bilirubin after AIS suggests a good prognosis. These findings imply that the liver play the key roles in the mechanism of AIS.PMID:36165803 | DOI:10.1080/01616412.2022.2119724
Source: Neurological Research - September 27, 2022 Category: Neurology Authors: Honglian Duan Zhe Cheng Ho Jun Yun Lipeng Cai Yanna Tong Zhenzhen Han Xiaokun Geng Yuchuan Ding Source Type: research

Endovascular treatment of patients with acute ischemic stroke and tandem occlusion due to internal carotid artery dissection: A multicenter experience
CONCLUSION: AIS patients with CD-TO were mostly treated with the retrograde approach with lower number of attempts per-procedure but it offered similar recanalization rates compared with the antegrade approach. Emergent carotid artery stenting (CAS) proved to be safe for CD management but it does not influence 3-months patients' clinical outcomes.PMID:35699167 | DOI:10.1177/19714009221108673
Source: Atherosclerosis - June 14, 2022 Category: Cardiology Authors: Valerio Da Ros Federica Pusceddu Simona Lattanzi Jacopo Scaggiante Fabrizio Sallustio Federico Marrama Monica Bandettini di Poggio Gianpaolo Toscano Francesca Di Giuliano Claudia Rolla-Bigliani Maria Ruggiero Niccolo Haznedari Alessandro Sgreccia Giuseppi Source Type: research

Prognostic value of the systemic inflammation response index in patients with acute ischemic stroke
ConclusionSIRI is an independent prognostic indicator for AIS. Elevated SIRI is associated with poor functional outcome of AIS. Our findings suggest the usefulness of SIRI to refine the risk stratification of unfavorable prognosis of AIS.
Source: Brain and Behavior - May 19, 2022 Category: Neurology Authors: Yaping Zhou, Yidi Zhang, Mingming Cui, Yuming Zhang, Xiuli Shang Tags: ORIGINAL ARTICLE Source Type: research

Full Reperfusion Without Functional Independence After Mechanical Thrombectomy in the Anterior Circulation
ConclusionA  variety of preinterventional factors may predict FR with substantial certainty, but the prediction model can still be improved by considering parameters only available after MT, in particular early neurological improvement.
Source: Klinische Neuroradiologie - May 9, 2022 Category: Radiology Source Type: research

Understanding Delays in MRI-based Selection of Large Vessel Occlusion Stroke Patients for Endovascular Thrombectomy
ConclusionMinimizing arrival-to-puncture time is important for outcomes. Real-world challenges exist in an MRI-based EVT selection protocol; avoiding double imaging is key to saving time. Racial/ethnic disparities require further study. Understanding variables associated with delay will inform protocol changes.
Source: Clinical Neuroradiology - April 29, 2022 Category: Neurology Source Type: research

Very early infective endocarditis after transcatheter aortic valve replacement
ConclusionA significant proportion of IE episodes following TAVR occurs within a few weeks following the procedure and are associated with dismal outcomes. Some baseline and TAVR procedural factors were associated with VE-IE, andStaphylococcus aureus and enterococci were the main causative pathogens. These results may help to select the more appropriate antibiotic prophylaxis in TAVR procedures and guide the initial antibiotic therapy in those cases with a clinical suspicion of IE.Graphical abstractVery early infective endocarditis after trans-catheter aortic valve replacement. VE-IE indicates very early infective endocard...
Source: Clinical Research in Cardiology - March 9, 2022 Category: Cardiology Source Type: research

Prognosis associated with asymptomatic intracranial hemorrhage after acute ischemic stroke: a systematic review and meta-analysis
ConclusionsOur results indicate that compared with patients without ICH, those who developed aICH during the acute stage of ischemic stroke had an increasing risk of worse outcome, especially in patients with endovascular therapy.
Source: Journal of Neurology - March 8, 2022 Category: Neurology Source Type: research

Seeing the good in the bad: actual clinical outcome of thrombectomy stroke patients with formally unfavorable outcome
ConclusionDichotomizing the mRS into favorable and unfavorable outcome does not do justice to the full spectrum of stroke. Patients with formal unfavorable outcome after mRS can improve neurologically, achieve treatment goals, and even regain their admission or pre-stroke mRS.
Source: Neuroradiology - March 8, 2022 Category: Radiology Source Type: research