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Infectious Disease: COVID-19

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Total 5889 results found since Jan 2013.

Factors contributing to poor COVID-19 outcomes in diabetic patients: Findings from a single-center cohort study
This article is a retrospective cohort study that include diabetic patients hospitalized with COVID-19 infection. A definition of diabetes was based on th e past history of diabetes or if the HbA1c was 6.5% or higher. Demographics, clinical characteristics, comorbidities, laboratory results, and complications were extracted from the electronic medical records. The mortality rate increased with increasing age (from 5.56% in younger patients to 46% in t he elderly) and with severity (from 25.71% in moderate cases to 43.77% in critical cases). We found that a critical severity on admission (OR: 5.26, 95% CI: 1.28–21.66,p = ...
Source: PLoS One - August 31, 2023 Category: Biomedical Science Authors: Nosayba Al-Azzam Source Type: research

Neurological manifestations of SARS-CoV-2: complexity, mechanism and associated disorders
CONCLUSIONS: SARS-CoV-2 can lead to neurological complications, such as cerebrovascular manifestations, motor movement complications, and cognitive decline. COVID-19 infection can result in cerebrovascular symptoms and diseases, such as strokes and thrombosis. The virus can affect the neural system, disrupt cognitive function and cause neurological disorders. To combat the epidemic, it is crucial to repurpose drugs currently in use quickly and develop novel therapeutics.PMID:37649125 | PMC:PMC10469568 | DOI:10.1186/s40001-023-01293-2
Source: Cell Research - August 30, 2023 Category: Cytology Authors: Kritika Tyagi Prachi Rai Anuj Gautam Harjeet Kaur Sumeet Kapoor Ashish Suttee Pradeep Kumar Jaiswal Akanksha Sharma Gurpal Singh Ravi Pratap Barnwal Source Type: research

Fast Heartburn Relief Without Deadly Drugs
Since gastroesophageal reflux disease (GERD) was first identified in the early 1930s, the number of people experiencing heartburn has increased substantially. In fact, one study shows that in just 10 years, the number of people experiencing:1 Any GERD symptoms increased by 30% Symptoms at least once a week increased by 47% Severe GERD increased by 24% While these numbers are concerning, I’ll admit they’re not surprising considering the typical American diet. Our nutrition-less, grain-based diet of carbohydrates and starches has wrecked our health and made our bodies behave in ways nature never intended. This has led ...
Source: Al Sears, MD Natural Remedies - August 28, 2023 Category: Complementary Medicine Authors: Jacob Tags: Health Heart Health Natural Cures Nutrition Source Type: news

Increased neuropil antibody prevalence in COVID-19 patients with acute ischemic stroke
CONCLUSION: Our results confirm the presence of neuropil antibodies in patients with COVID-19 infection and identify a putative antibody-driven association between AIS and COVID-19. The antigenic targets and potential pathogenic action of these antibodies need to be further explored.PMID:37634189 | DOI:10.1080/01616412.2023.2252282
Source: Cell Research - August 27, 2023 Category: Cytology Authors: Birg ül Baştan Ece Erda ğ Turgeon Elif Şanlı Muhammet Duran Bayar Aysel B üşra Şişman Miray Atacan Ya şgüçlükal Cem I Smail K üçükali Erdem T üzün Sefer G ünaydın Source Type: research

Feasibility of a Virtual-Reality-Enabled At-Home Telerehabilitation Program for Stroke Survivors: A Case Study
J Pers Med. 2023 Aug 3;13(8):1230. doi: 10.3390/jpm13081230.ABSTRACTStroke rehabilitation is a lengthy procedure that is necessary for stroke recovery. However, stroke rehabilitation may not be readily available for patients who live rurally due to barriers such as transportation and expenses. This shortage in wearable technology, in turn, causes health disparity among the rural population, which was exacerbated by the COVID-19 pandemic restrictions. Telerehabilitation (TR) is a potential solution for stroke rehabilitation in rural areas. This one-case study aimed to examine the feasibility and safety of a technology-enabl...
Source: Rural Remote Health - August 25, 2023 Category: Rural Health Authors: Mohamed-Amine Choukou Elizabeth He Kelly Moslenko Source Type: research

Clinical characteristics and predictors for in-hospital mortality in adult COVID-19 patients: A retrospective single center cohort study in Vilnius, Lithuania
ConclusionsAge, congestive heart failure, obesity, COPD, prior stroke, and increased concentration of urea, LDH, CRP, IL-6, troponin I, ALT to AST ratio were identified to be the predictors for in-hospital mortality of COVID-19 patients.
Source: PLoS One - August 25, 2023 Category: Biomedical Science Authors: Ieva Kubiliute Source Type: research

Botulinum toxin use in patients with post-stroke spasticity: a nationwide retrospective study from France
ConclusionOur analysis of the exhaustive PMSI database showed a suboptimal implementation of BoNT-A treatment recommendations in France. BoNT-A treatment initiation and re-administration are low, particularly in patients with post-stroke spasticity. Further investigations may help explain this observation, and may target specific actions to improve spasticity-related care pathway.
Source: Frontiers in Neurology - August 23, 2023 Category: Neurology Source Type: research

Single-cell RNA sequencing and multiple bioinformatics methods to identify the immunity and ferroptosis related biomarkers of SARS-CoV-2 infections to ischemic stroke
CONCLUSION: We believe these genes (B4GALT5, CRISPLD2, F5, ACSL1, CREB5) may regulate the immune response and ferroptosis of multiple immune cells, mainly including monocytes, which may contribute to the development of COVID-19-related IS. In addition, these genes may be potential targets for the treatment of COVID-19-related IS.PMID:37606960 | DOI:10.18632/aging.204966
Source: Aging - August 22, 2023 Category: Biomedical Science Authors: Xiang Zhao Qingyu Liang Hao Li Zhitao Jing Dongmei Pei Source Type: research

P009/86 Infected giant pseudoaneurysm of extracranial internal carotid artery with extreme vascular tortuosity: Difficulty in accessing the devices in endovascular treatment
ConclusionWhen we deciding treatment strategy, surgery could not be considered due to uncontrolled infection and suggesting inflammatory/erosive changes. Because of no collateral flow, carotid sacrifice could not be considered. Endovascular treatment is preferred option, but treatment strategy should be personalized.Disclosure of InterestNothing to disclose
Source: Journal of NeuroInterventional Surgery - August 21, 2023 Category: Neurosurgery Authors: Yang, J.-C., Hong, C. E., Han, M. H., Lee, J. Tags: 4.3 CASE PROPOSAL - Acute ischemic stroke Source Type: research

The Minnesota Medical Operations Coordination Center (MOCC): A COVID-19 statewide response to ensure access to critical care and medical-surgical beds
Chest. 2023 Aug 17:S0012-3692(23)05277-7. doi: 10.1016/j.chest.2023.08.016. Online ahead of print.ABSTRACTBACKGROUND: COVID-19 led to unprecedented inpatient capacity challenges particularly in Intensive Care Units (ICUs), which spurred development of statewide or regional placement centers for coordinating transfer (load balancing) of adult patients needing intensive care to hospitals with remaining capacity.RESEARCH QUESTION: Do Medical Operations Coordination Centers (MOCC) augment patient placement during times of severe capacity challenges?STUDY DESIGN AND METHODS: The Minnesota MOCC was established with focus on tran...
Source: Chest - August 19, 2023 Category: Respiratory Medicine Authors: Karyn D Baum Lauren Vlaanderen Walter James Mary Jo Huppert Paul Kettler Christine Chell Adam Shadiow Helen Strike Kay Greenlee Daniel Brown John L Hick Jack M Wolf Mark B Fiecas Erin McLachlan Judy Seaberg Sean MacDonnell Sarah Kesler Jeffrey R Dichter Source Type: research