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Infectious Disease: COVID-19
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E-166 The effect of covid-19 on treatment and outcomes following ischemic stroke: a national assessment
ConclusionThis study identified a relationship between COVID-19 diagnosis and worse outcomes for each metric assessed. Most notably, even when controlling for disease-related factors, patients with COVID-19 were significantly less likely to undergo mechanical thrombectomy. Further, COVID-19 was associated with increased in-hospital mortality and worsened discharge disposition, although the exact causal relationship of this is unclear. Several factors might underly this, ranging from systemic/multisystem inflammation and worsened disease severity to logistical barriers to treatment caused by COVID-19. Further research is ne...
Source: Journal of NeuroInterventional Surgery - July 30, 2023 Category: Neurosurgery Authors: Dallas, J., Liu, K., Wenger, T., Lin, M., Ding, L., Attenello, F., Mack, W. Tags: SNIS 20th annual meeting electronic poster abstracts Source Type: research
E-177 Treatment of ischemic stroke in patients diagnosed with covid-19: a matched analysis of the national inpatient sample
ConclusionsIn this matched NIS analysis of patients treated for ischemic stroke with a concomitant COVID diagnosis, we demonstrate that EVT trends towards, although nonsignificant, higher rates of favorable functional outcomes when compared to medically managed patients.Abstract E-177 Table 1Patients with COVID and Acute Ischemic Stroke Comparing medical management vs EVT 1:1 Nearest Neighbor Matching for EVT based on Age, NIHSS, Gender, and Comorbidities Medically Managed N = 495 1 Endovascular ThrombectomyN = 495 1 p-value 2 Age in years at admission 66.82 ± 16.98 (19.00-90.00), (1.77) 65.67 ± 14.81 (28...
Source: Journal of NeuroInterventional Surgery - July 30, 2023 Category: Neurosurgery Authors: Heskett, C., Fry, L., Brake, A., De Stefano, F., Morey, K., Lei, C., Alkiswani, A., Le, K., Peterson, J., Ebersole, K. Tags: SNIS 20th annual meeting electronic poster abstracts Source Type: research
E-223 Improved time to diagnosis with portable MR imaging
ConclusionPortable MRI is a promising innovation with the aim to expand patient access and improve diagnostic times so that critical and potential lifesaving imaging diagnoses can be promptly treated with the urgency that is required. While initial analysis provides evidence that portable MRI has advantages over conventional MRI systems including workflow efficiency and improved patient imaging times, this will need to be compared to the unfortunate negative drawbacks of lessened image resolution and limited imaging sequences that come with the convenience of portable MRI systems. If the hypothesis is further corroborated,...
Source: Journal of NeuroInterventional Surgery - July 30, 2023 Category: Neurosurgery Authors: Richardson, O., Richardson, A., Mukherjee, S. Tags: SNIS 20th annual meeting electronic poster abstracts Source Type: research
E-241 Clinicopathologic analysis of COVID-19 associated thrombi in the setting of large vessel occlusion: a prospective case control study
ConclusionThrombi retrieved from COVID-19 positive stroke patients demonstrated RBC predominance. This finding requires further investigation using appropriate immunohistochemical techniques in a larger cohort of patients.Abstract E-241 Figure 1Abstract E-241 Figure 2COVID-19 positive patient thrombus; stained with H&E demonstrating predominantly RBCs (solid yellow arrow) with interspersed fibrin (solid black arrow) and platelets. Original magnification X100Disclosures R. Floresca: None. F. Sheriff: None. J. Lavezo: None. M. Chaudhury: None. G. Colina: None. R. Regenhardt: None. V. Gupta: None. G. Rodriguez: None. A. Maud: None.
Source: Journal of NeuroInterventional Surgery - July 30, 2023 Category: Neurosurgery Authors: Floresca, R., Sheriff, F., Lavezo, J., Chaudhury, M., Colina, G., Regenhardt, R., Gupta, V., Rodriguez, G., Maud, A. Tags: SNIS 20th annual meeting electronic poster abstracts Source Type: research
Correlation between Hepatocyte Growth Factor (HGF) with D-Dimer and Interleukin-6 as Prognostic Markers of Coagulation and Inflammation in Long COVID-19 Survivors
Curr Issues Mol Biol. 2023 Jul 8;45(7):5725-5740. doi: 10.3390/cimb45070361.ABSTRACTIn general, an individual who experiences the symptoms of Severe Acute Respiratory Syndrome Coronavirus 2 or SARS-CoV-2 infection is declared as recovered after 2 weeks. However, approximately 10-20% of these survivors have been reported to encounter long-term health problems, defined as 'long COVID-19', e.g., blood coagulation which leads to stroke with an estimated incidence of 3%, and pulmonary embolism with 5% incidence. At the time of infection, the immune response produces pro-inflammatory cytokines that stimulate stromal cells to pro...
Source: Current Issues in Molecular Biology - July 28, 2023 Category: Molecular Biology Authors: Bena Zaira Trilis Yulianti Jutti Levita Source Type: research
