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Infectious Disease: COVID-19
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Contemporary outcomes of long-term anticoagulation in COVID-19 patients: a regression matched sensitivity analysis of the national inpatient sample
CONCLUSIONS: Compared to COVID-19 patients not on long-term anticoagulation, we observed lower in-hospital mortality, stroke and acute myocardial infarction in COVID-19 patients on long-term anticoagulation. Prospective studies are needed for optimal anticoagulation strategies in hospitalized patients.PMID:37409406 | DOI:10.1080/14779072.2023.2234282
Source: Expert Review of Cardiovascular Therapy - July 6, 2023 Category: Cardiology Authors: Amro Taha Irisha Badu Harigopal Sandhyavenu Varun Victor Sanchit Duhan Lalitsiri Atti Hasham Masood Qureshi Thatiana Schulze Goni Bijeta Keisham Vasantha Sandhya Venu Harshith Thyagaturu Karthik Gonuguntla Waqas Ullah Himanshu Deshwal Sudarshan Balla Source Type: research
Preface: Special issue “Brain Proteostasis in Health and Disease”
The special issue “Brain Proteostasis in Health and Disease” features both original and review articles written by specialists in the field of protein homeostasis. Deregulation of adequate proteostasis may contribute to brain diseases, including several neuropsychiatric and neurodegenerative conditions. Therefore , delineating the processes underlying protein synthesis, folding, stability, function, and degradation in brain cells is key to promoting brain function and identifying effective therapeutic options for neurological disorders. This special issue covers the roles of protein homeostasis in several me chanisms t...
Source: Journal of Neurochemistry - July 6, 2023 Category: Neuroscience Authors: Mychael V. Lourenco Tags: EDITORIAL Source Type: research
Initial therapeutic anticoagulation with rivaroxaban compared to prophylactic therapy with heparins in moderate to severe COVID-19: results of the COVID-PREVENT randomized controlled trial
ConclusionsTherapeutic anticoagulation with rivaroxaban compared to prophylactic anticoagulation with a heparin did not improve surrogates of clinical outcome in patients with moderate to severe COVID-19. Whether initial rivaroxaban at therapeutic doses might be superior to thromboprophylaxis in patients with COVID-19 and a high risk as defined byd-dimer > 2 ULN needs confirmation in further studies.Graphical abstract
Source: Clinical Research in Cardiology - July 5, 2023 Category: Cardiology Source Type: research
Lactate Dehydrogenase and Hemorrhagic Stroke During Extracorporeal Membrane Oxygenation for COVID-19
ConclusionElevated LDH prior to ECMO cannulation is associated with a higher incidence of HS during device support. LDH can risk stratify cases for impending cerebral bleeding during ECMO.
Source: Lung - July 4, 2023 Category: Respiratory Medicine Source Type: research
A Statewide Population-Linkage Study on the Impact of Atrial Fibrillation on Outcomes in 145,293 Patients Admitted With COVID-19
Atrial fibrillation (AF) is common in COVID-19 patients. The impact of AF on major adverse cardiovascular events (MACE defined as all-cause mortality, myocardial infarction, ischaemic stroke, heart failure or revascularisation), recurrent admissions with AF, and venous thromboembolism in patients hospitalised with COVID-19 is not well-defined.
Source: Heart, Lung and Circulation - July 1, 2023 Category: Cardiology Authors: J. Ne, C. Chow, A. Yan, I. Rubenis, S. Virk, V. Chow, K. Hyun, L. Kritharides, D. Brieger, A. Ng Source Type: research
Stroke Mortality Among Blacks, Whites Before and During COVID-19 Stroke Mortality Among Blacks, Whites Before and During COVID-19
This analysis found that the racial gap in stroke mortality widened from the prepandemic period to the pandemic period.Morbidity & Mortality Weekly Report
Source: Medscape Today Headlines - June 30, 2023 Category: Consumer Health News Tags: Public Health & Prevention Journal Article Source Type: news
High AST/ALT Ratio Is Associated with Cardiac Involvement in Acute COVID-19 Patients
Conclusion: High AST/ALT ratio is related to impaired right ventricular function parameters with CMRI and echocardiography after recovery from acute COVID-19. Assessment of AST/ALT ratio at hospital admission may be used to assess the risk of cardiac involvement in COVID-19 disease, and these patients may require closer follow-up during and after the course of COVID-19.PMID:37374367 | PMC:PMC10305090 | DOI:10.3390/medicina59061163
Source: Medicina (Kaunas) - June 28, 2023 Category: Universities & Medical Training Authors: Mesut Karatas Nursen Keles Kemal Emrecan Parsova Hatice Ozge Ciftci Sercin Ozkok Erkan Kahraman Furkan Durak Cevdet Ugur Kocogullari Nurettin Yiyit Source Type: research
