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Specialty: Neurology
Source: Neurological Research
Condition: Ischemic Stroke

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Total 364 results found since Jan 2013.

Evaluation of intracranial and extracranial atherosclerotic lesions in patients with symptomatic coronary artery disease.
Conclusions: The prevalence of ECAD, ICAD and EICAD is high in patients with CAD, and the presence of these conditions is positively correlated with the extent and degree of CAD. Evaluations of ECAD and ICAD should be highly recommended for CAD patients to reduce the future risk of cardiovascular diseases. PMID: 32284016 [PubMed - as supplied by publisher]
Source: Neurological Research - April 16, 2020 Category: Neurology Tags: Neurol Res Source Type: research

Assessment of the manifestations of atrial fibrillation in patients with acute cerebral stroke - a single-center study based on 998 patients.
Discussion: The above data should prompt neurologists, cardiologists and family doctors to try to detect AF as a risk factor for ischemic stroke which worsens patient prognosis, prolongs hospital stay and contributes to increase in mortality, especially when more effective drug treatment is currently possible. PMID: 32241245 [PubMed - as supplied by publisher]
Source: Neurological Research - April 5, 2020 Category: Neurology Tags: Neurol Res Source Type: research

Human urinary kallidinogenase in treating acute ischemic stroke patients: analyses of pooled data from a randomized double-blind placebo-controlled phase IIb and phase III clinical trial.
Conclusion: HUK is safe and provides potential clinical benefits as a treatment for acute ischemic stroke. Further large post-marketing observational studies are needed. PMID: 32138624 [PubMed - as supplied by publisher]
Source: Neurological Research - March 7, 2020 Category: Neurology Tags: Neurol Res Source Type: research

The effect of intravenous ginkgolide on clinical improvement of patients with acute ischemic stroke.
Conclusion: Intravenous ginkgolide may improve the outcome of acute ischemic stroke. Differences in effect between pre-marketing and post-marketing studies may be associated with gender, time of onset to enrollment and severity of stroke. PMID: 32048567 [PubMed - as supplied by publisher]
Source: Neurological Research - February 13, 2020 Category: Neurology Tags: Neurol Res Source Type: research

Increasing trimethylamine N-oxide levels as a predictor of early neurological deterioration in patients with acute ischemic stroke.
Conclusions: Our study indicated that increasing TMAO levels at admission might be associated with END after acute ischemic stroke. PMID: 31928326 [PubMed - as supplied by publisher]
Source: Neurological Research - January 14, 2020 Category: Neurology Tags: Neurol Res Source Type: research

An analysis of the risk of perioperative ischemic stroke in patients undergoing non-cardiovascular and non-neurological surgeries.
Conclusions: History of stroke and smoking, renal insufficiency, and low HDL-C are independent risk factors for PIS. It is feasible to assess the risk of stroke in preoperative patients using PCE in clinical practice. PMID: 31903867 [PubMed - as supplied by publisher]
Source: Neurological Research - January 7, 2020 Category: Neurology Tags: Neurol Res Source Type: research

Inflammatory biomarkers and risk of ischemic stroke and subtypes: A 2-sample Mendelian randomization study.
Conclusions: Our study did not find convincing evidence to support that inflammatory biomarkers like IL-1Ra, sIL-6R and CRP are causally associated with the risk of ischemic stroke or its subtypes. PMID: 31900081 [PubMed - as supplied by publisher]
Source: Neurological Research - January 6, 2020 Category: Neurology Tags: Neurol Res Source Type: research

Association between CPR-related genetic variants and risk of ischemic stroke: a nested case-control study.
Conclusions: Our study showed genetic variants of CRP-related genes were associated with risk of ischemic stroke. Our findings could provide useful data for the etiology of ischemic stroke. PMID: 31584351 [PubMed - as supplied by publisher]
Source: Neurological Research - October 5, 2019 Category: Neurology Tags: Neurol Res Source Type: research

Thrombolysis with rhPro-UK 3 to 6 hours after embolic stroke in rat.
Conclusions: RhPro-UK had an obvious therapeutic effect on ischemic stroke caused by thrombosis, and could be started within 4.5 h TTW with less side effects of cerebral hemorrhage than that of UK. PMID: 31584350 [PubMed - as supplied by publisher]
Source: Neurological Research - October 5, 2019 Category: Neurology Tags: Neurol Res Source Type: research

Inpatient statin use and stroke recurrence in patients with or without diabetes mellitus.
Conclusion: Inpatient statin use was associated with lower stroke recurrence in non-diabetic patients after acute ischaemic stroke, but no definite association between inpatient statin use and stroke recurrence in patients with diabetes mellitus was found. PMID: 31328681 [PubMed - as supplied by publisher]
Source: Neurological Research - July 23, 2019 Category: Neurology Tags: Neurol Res Source Type: research

Effect of a novel designed intensive patient care program on cognitive impairment, anxiety, depression as well as relapse free survival in acute ischemic stroke patients: a randomized controlled study.
Conclusions: IPCP presents with a positive influence on improving cognitive impairment and decreasing anxiety as well as depression, while a less effect on improving RFS in AIS patients. Abbreviation: IPCP: intensive patient care program; RFS: relapse free survival; AIS: acute ischemic stroke; MRA: magnetic resonance angiography; ITT: intention-to-treat; LOCF: last observation carried forward. PMID: 31266412 [PubMed - as supplied by publisher]
Source: Neurological Research - July 4, 2019 Category: Neurology Tags: Neurol Res Source Type: research

Association between socioeconomic status and prognosis after ischemic stroke in South China.
Conclusions: Patients with low income, family caregiver, and no insurance have a poorer prognosis after ischemic stroke that can be partly explained by intermediate variable in the patients' demographic characteristics, cardiovascular disease, behavior lifestyle, and stroke severity. Abbreviations: DALYs: disability-adjusted life years; SES: socioeconomic status; FMC: free medical care; MIUR: medical insurance for urban residents; MIUE: medical insurance for urban employees; NCMS: new rural cooperative medical scheme ; NIHSS: National Institute of Health Stroke Scale ; mRS: modified Rankin scale; OR: odds ratios; CI: confi...
Source: Neurological Research - June 19, 2019 Category: Neurology Tags: Neurol Res Source Type: research

Clinical potential of pre-reperfusion hypothermia in ischemic injury.
Authors: Han Y, Rajah GB, Hussain M, Geng X Abstract The damage caused by ischemic stroke is mostly refractory to medical therapies and amounts to a substantial degree of mortality and morbidity in the world. The core tenet of treatment for acute ischemic stroke (AIS) is to save 'reversible' ischemic tissue (ischemic penumbra) as quickly as possible within a limited therapeutic time window. The neuroprotective effect of hypothermia has been proven previously in a large number of animal experiments and clinical trials. Some of these animal and human studies have shown that pre-reperfusion hypothermia can reduce myoc...
Source: Neurological Research - May 1, 2019 Category: Neurology Tags: Neurol Res Source Type: research

Balloon-mounted versus self-expanding stents for symptomatic intracranial vertebrobasilar artery stenosis combined with poor collaterals.
CONCLUSIONS: Stenting for patients with severe symptomatic intracranial vertebrobasilar arterial stenosis with poor collaterals can be performed safely with efficacy. Patients treated with balloon-mounted stents appear to have shorter operative times and lower re-stenosis rates than treated with self-expanding stents. PMID: 31030623 [PubMed - as supplied by publisher]
Source: Neurological Research - May 1, 2019 Category: Neurology Tags: Neurol Res Source Type: research

Microalbuminuria in patients with acute ischemic stroke.
CONCLUSIONS: MAU was found in approximately one-third of patients with acute ischemic stroke. It was correlated with the severity of cerebral infarction at admission and clinical outcomes at 3 months after onset and could be used as a potential indicator of poor prognosis in ischemic stroke patients. PMID: 30931822 [PubMed - as supplied by publisher]
Source: Neurological Research - April 3, 2019 Category: Neurology Tags: Neurol Res Source Type: research