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Source: The Journal of Heart and Lung Transplantation

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Total 231 results found since Jan 2013.

Cerebral Vasoreactivity in HeartMate 3 Patients
While rates of stroke have declined with the HeartMate3 (HM3) continuous flow (CF) left ventricular assist device (LVAD), the impact of non-pulsatile flow and artificial pulse physiology on cerebrovascular function is not known. We hypothesized that improved hemodynamics and artificial pulse physiology of HM3 patients would augment cerebrovascular metabolic reactivity (CVR) compared with HeartMate II (HMII) CF-LVAD and heart failure (HF) patients.
Source: The Journal of Heart and Lung Transplantation - May 21, 2021 Category: Transplant Surgery Authors: Eric J. St öhr, Ruiping Ji, Koichi Akiyama, Giulio Mondellini, Lorenzo Braghieri, Alberto Pinsino, John R. Cockcroft, Melana Yuzefpolskaya, Amrin Amlani, Veli K. Topkara, Hiroo Takayama, Yoshifumi Naka, Nir Uriel, Koji Takeda, Paolo C. Colombo, Barry J. Tags: Original Research Article Source Type: research

Risk Factors and Prognostic Implications of Perioperative Stroke after Heart Transplantation: An Analysis of the United Network for Organ Sharing Database 2009-2019
The purpose of our study was to evaluate risk factors and prognostic implications of perioperative stroke in heart transplantation.
Source: The Journal of Heart and Lung Transplantation - March 20, 2021 Category: Transplant Surgery Authors: T. Kitai, T. Okamoto, A. Briasoulis, H. Niikawa, K. McCurry, P. Alvarez Tags: (248) Source Type: research

Low Left Ventricular Stroke Work Index is Associated with a Poor Prognosis in LVAD Patients
Hemocompatibility-related adverse events (HRAE) are thought to be largely driven by the pump-patient interaction. We hypothesized that patients with left ventricular assist devices (LVADs) with low left ventricular stroke work index (LVSWI), and thus less native contribution to total flow, would have more adverse clinical outcomes.
Source: The Journal of Heart and Lung Transplantation - March 20, 2021 Category: Transplant Surgery Authors: A.J. Kanelidis, T. Miller, M. Belkin, U. Siddiqi, D. Rogers, N. Uriel, T. Song, T. Ota, S. Kalantari, N. Sarswat, A. Nguyen, B.B. Chung, G. Kim, B. Smith, V. Jeevanandam, S. Pinney, J. Grinstein Tags: (226) Source Type: research

Hyperhomocysteinemia and Oxidative Stress May Predict the Risk of Stroke in Patients Supported by Continuous Flow Left Ventricular Assist Devices
Stroke is one of the leading complications during CF-LVAD support. The purpose of this observational study was to investigate the temporal relationship of circulating homocysteine (Hcy) and oxidative stress as potential markers to identify CF-LVAD patients at risk for developing postoperative strokes.
Source: The Journal of Heart and Lung Transplantation - March 20, 2021 Category: Transplant Surgery Authors: N.K. Mondal, H.K. Lamba, S.I. Hudson, C. Hochman-Mendez, A.E. Shafii, G. Loor, A. Mattar, R.K. Ghanta, O. Frazier, K.K. Liao Tags: (386) Source Type: research

Prolonged Circulatory Arrest is Not Associated with Stroke or Mortality after Pulmonary Thromboendarterectomy
Patients with chronic thromboembolic pulmonary hypertension (CTEPH) frequently present with extensive distal clot burden, which adds complexity to pulmonary thromboendarterectomy (PTE). Complete endarterectomy often necessitates prolonged periods of hypothermic circulatory arrest (HCA), the ramifications of which are poorly understood. Objectives were to describe the association of HCA time with post-operative neurologic complications, operative mortality and other major morbidity after PTE.
Source: The Journal of Heart and Lung Transplantation - March 20, 2021 Category: Transplant Surgery Authors: J.L. Armstrong, A.M. Vekstein, A. Seas, C.M. Wojnarski, A.M. Ganapathi, J.C. Haney Tags: (433) Source Type: research

Improvement in Right Ventricular Stroke Work Index in Cardiogenic Shock Associated with Excellent Durable Left Ventricular Assist Implantation Results
Cardiogenic shock results from inadequate cardiac output to satisfy organ perfusion with potential need for pharmacologic and mechanical circulatory support for survival. Impella 5.0 insertion is used as a rescue device and bridge to durable mechanical circulatory support. We sought to evaluate changes in right ventricular parameters in patients bridged with Impella 5.0 undergoing durable left ventricular device implantation (LVAD).
Source: The Journal of Heart and Lung Transplantation - March 20, 2021 Category: Transplant Surgery Authors: M.P. Rogers, B.D. Mackie, R.L. Hooker Tags: (447) Source Type: research

Incidence, Predictors and Outcomes of Stroke Following Cardiac Transplantation
Stroke after heart transplantation (HT) is a major cause of morbidity and mortality. Less is known about the risk factors associated with stroke in the current era of increasing HT being performed in older patients and with advances in immunosuppressive (IS) therapies. We aimed to determine the incidence, predictors and outcomes of stroke after HT.
Source: The Journal of Heart and Lung Transplantation - March 20, 2021 Category: Transplant Surgery Authors: H. Alnsasra, R. Asleh, N. Kumar, T. Toya, C. Lopez, W.K. Kremers, B. Edwards, R.C. Daly, S.S. Kushwaha Tags: (548) Source Type: research

Percent Increase in Left Ventricular Stroke Work Index and Right Ventricular Stroke Work Index after Milrinone Infusion Predicts Escalation of Therapy and Mortality
We hypothesized that changes in biventricular function would approximate myocardial reserve and predict outcomes.
Source: The Journal of Heart and Lung Transplantation - March 20, 2021 Category: Transplant Surgery Authors: U.A. Siddiqi, M. Belkin, S. Kalantari, A. Kanelidis, T. Miller, N. Sarswat, A. Nguyen, B. Chung, G. Kim, B. Smith, V. Jeevanandam, S. Pinney, J. Grinstein Tags: (638) Source Type: research

Prognostic Role of Simultaneous Assessment of Biventricular Function Using Left Ventricular Stroke Work Index and Right Ventricular Stroke Work Index
We hypothesized that simultaneous assessment of biventricular function could predict clinical outcomes.
Source: The Journal of Heart and Lung Transplantation - March 20, 2021 Category: Transplant Surgery Authors: U.A. Siddiqi, M. Belkin, S. Kalantari, A. Kanelidis, T. Miller, N. Sarswat, A. Nguyen, B. Chung, G. Kim, B. Smith, V. Jeevanandam, S. Pinney, J. Grinstein Tags: (632) Source Type: research

Elevated Blood Pressure Before Left Ventricular Assist Device Support Implant is Associated with an Increased Risk of Stroke
Despite the recent advances in Left Ventricular Assist Device (LVAD) therapy, stroke remains a frequent and catastrophic complication. Hypertension (HTN) after LVAD implant has been associated with an increased risk of stroke, but the association between HTN before LVAD implant and stroke has never been studied. We hypothesized that LVAD patients with elevated blood pressure (BP) during outpatient visits before the LVAD implant may have an increased risk of stroke.
Source: The Journal of Heart and Lung Transplantation - March 20, 2021 Category: Transplant Surgery Authors: F. Castagna, S. Patel, S. Vukelic, S. Madan, O. Saeed, D. Sims, D. Goldstin, U.P. Jorde Tags: (978) Source Type: research

Clinical Characteristics and Outcomes of Extracorporeal Membrane Oxygenation Support in COVID-19: Retrospective Study of Single Center Experience
This study is to summarize the clinical features, and outcomes of patients with severe ARDS due to COVID-19 treated with ECMO. We analyzed the incidence of morbidity including ischemic/hemorrhagic stroke, gastrointestinal bleeding, pump malfunction, oxygenator dysfunction, infection during VV ECMO.
Source: The Journal of Heart and Lung Transplantation - March 20, 2021 Category: Transplant Surgery Authors: C. Kurihara, A. Manerikar, V. Kandula, A. Bharat Tags: 1004 Source Type: research

Risk of Stroke in Patients with Left Ventricular Assist Device Who Had Myocardial Recovery
The risk factors and incidence rates of stroke after implantation of left ventricular assist devices (LVAD) are well established. Little is known about the factors associated with stroke after LVAD explantation in patients who have had a myocardial recovery.
Source: The Journal of Heart and Lung Transplantation - March 20, 2021 Category: Transplant Surgery Authors: S. Sundaravel, M. Urban, J. Um, A. Albulushi Tags: 1003 Source Type: research

Bridge from Central Extracorporeal Life Support to Durable LVAD in Acute Heart Failure Elevates a Risk of Stroke Long-Term
This study aimed to review outcomes of this bridge strategy from central ECLS to durable LVAD, as compared to those of primary LVAD implantation.
Source: The Journal of Heart and Lung Transplantation - March 20, 2021 Category: Transplant Surgery Authors: K. Tonai, S. Fukushima, N. Tadokoro, N. Fukushima, T. Fujita Tags: (994) Source Type: research

Impact of Mitral Valve Prosthesis on Stroke after Insertion of Veno-Arterial Membrane Oxygenation for Postcardiotomy Shock
This study focused on stroke after valve surgery requiring VA-ECMO.
Source: The Journal of Heart and Lung Transplantation - March 20, 2021 Category: Transplant Surgery Authors: S. Ohira, D. Spielvogel, R. Malekan, J.B. Goldberg, P.J. Spencer, S.L. Lansman, M. Kai Tags: 1026 Source Type: research

HVAD Lavare Cycle Reduces Cerebrovascular Events and Improves Survival
The Lavare Cycle (LC) is a pre-programmed speed modulation algorithm in the HVAD device designed to automatically increase both ventricular and pump washing. The ReVOLVE trial suggested a reduction in adverse outcomes including stroke. We assessed the effect LC ON compared to LC OFF on HVAD implants.
Source: The Journal of Heart and Lung Transplantation - March 20, 2021 Category: Transplant Surgery Authors: C.G. Gidea, A. Emmarco, A. Reyentovich, J. Pavone, A. Fargnoli, T. Saraon, S. Rao, R. Goldberg, B. Kadosh, Z. Kon, N. Moazami, D. Smith Tags: 1067 Source Type: research