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Source: The Journal of Heart and Lung Transplantation
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Total 231 results found since Jan 2013.
A longer waiting game: Bridging children to heart transplant with the Berlin Heart EXCOR device—the United Kingdom experience
Conclusions: BH use in the UK has allowed significant increases in the number of children with end-stage heart failure who can be successfully bridged to transplant and the length of time they can be supported. The total number of transplants has not increased.
Source: The Journal of Heart and Lung Transplantation - September 23, 2013 Category: Transplant Surgery Authors: Jane Cassidy, Troy Dominguez, Simon Haynes, Michael Burch, Richard Kirk, Aparna Hoskote, Jon Smith, Matthew Fenton, Massimo Griselli, Tain-Yen Hsia, Lee Ferguson, Carin Van Doorn, Asif Hasan, Ann Karimova Tags: Original Clinical Science Source Type: research
Gastrointestinal bleeding and subsequent risk of thromboembolic events during support with a left ventricular assist device
Background: Modern left ventricular assist devices (LVAD) require anti-coagulation (AC) with warfarin and anti-platelet therapy to prevent thromboembolic complications in patients. Gastrointestinal bleeding (GI) is a significant adverse event in these patients and treatment typically requires reduction or elimination of AC or anti-platelet therapy. It is not known whether alterations in AC to treat GI bleeding influence subsequent risk of thromboembolic (TE) events during LVAD support.Methods: Between July 2003 and September 2011, 389 patients (308 male) underwent implantation of a continuous-flow LVAD at the University of...
Source: The Journal of Heart and Lung Transplantation - September 9, 2013 Category: Transplant Surgery Authors: John M. Stulak, Dustin Lee, Jonathon W. Haft, Matthew A. Romano, Jennifer A. Cowger, Soon J. Park, Keith D. Aaronson, Francis D. Pagani Tags: Featured Articles Source Type: research
Diagnosis of hemolysis and device thrombosis with lactate dehydrogenase during left ventricular assist device support
Mechanical circulatory support (MCS) with a continuous-flow (CF) rotary pump is associated with low levels of hemolysis during normal pump operation. Clinically significant hemolysis can be an early sequelae of pump thrombus. Left ventricular assist device (LVAD) thrombosis may result in stroke, peripheral embolism, heart failure, device exchange, and death. The timely detection of pump thrombus remains challenging.
Source: The Journal of Heart and Lung Transplantation - August 21, 2013 Category: Transplant Surgery Authors: Palak Shah, Vivek M. Mehta, Jennifer A. Cowger, Keith D. Aaronson, Francis D. Pagani Tags: Research Correspondence Source Type: research
A cardioprotective preservation strategy employing ex vivo heart perfusion facilitates successful transplant of donor hearts after cardiocirculatory death
Conclusion: In this experimental model of DCD, an EVHP strategy using initial reperfusion with a tepid adenosine-lidocaine cardioplegia and continuous myocardial perfusion minimizes myocardial injury and improves short-term post-transplant function compared with the current EVHP strategy using cold hyperkalemic cardioplegia before organ procurement and transplantation.
Source: The Journal of Heart and Lung Transplantation - June 27, 2013 Category: Transplant Surgery Authors: Christopher W. White, Ayyaz Ali, Devin Hasanally, Bo Xiang, Yun Li, Paul Mundt, Matthew Lytwyn, Simon Colah, Julianne Klein, Amir Ravandi, Rakesh C. Arora, Trevor W. Lee, Larry Hryshko, Stephen Large, Ganghong Tian, Darren H. Freed Tags: Original Pre-Clinical Science Source Type: research
Upsizing of a Berlin Heart EXCOR pediatric left ventricular assist device to achieve adequate flow requirement
We report the case of an 8-kg infant who required pump upsizing to provide adequate LV unloading and systemic perfusion.
Source: The Journal of Heart and Lung Transplantation - June 3, 2013 Category: Transplant Surgery Authors: Yishay Orr, Aamir Jeewa, Mary Claire McGarry, E. Dean McKenzie, Iki Adachi Tags: Case Anecdotes, Comments and Opinions Source Type: research
Right ventricular stroke work index as a negative predictor of mortality and initial hospital stay after lung transplantation
Conclusions: This study demonstrates an association between 1-year mortality, initial hospital and intensive care length of stay, and pre-LTx RVSWI. Increased mPAP is a known risk for outcomes in LTx patients. Our findings support this fact and also show increased mortality with elevation of RVSWI, demonstrating the value of RV function in the assessment of risk for pre-LTx patients.
Source: The Journal of Heart and Lung Transplantation - April 8, 2013 Category: Transplant Surgery Authors: Hilary F. Armstrong, P. Christian Schulze, Tomoko S. Kato, Matthew Bacchetta, Wilawan Thirapatarapong, Matthew N. Bartels Tags: Featured Articles Source Type: research
