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Source: The Journal of Heart and Lung Transplantation
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Total 231 results found since Jan 2013.
Detection of inflow obstruction in left ventricular assist devices by accelerometer: A porcine model study
Left ventricular assist devices (LVAD) provide circulatory blood pump support for severe heart failure patients. Pump inflow obstructions may lead to stroke and pump malfunction. We aimed to verify in vivo that gradual inflow obstructions, representing prepump thrombosis, are detectable by a pump-attached accelerometer, where the routine use of pump power (PLVAD) is deficient.
Source: The Journal of Heart and Lung Transplantation - April 4, 2023 Category: Transplant Surgery Authors: Didrik Lilja, Itai Schalit, Andreas Espinoza, Arnt Eltvedt Fiane, Gry Dahle, Helen Littorin-Sandbu, Fred-Johan Pettersen, Kristoffer Engh Russell, Amrit Paul Singh Thiara, Ole Jakob Elle, Per Steinar Halvorsen Tags: Original Pre-Clinical Science Source Type: research
Elective Cardiopulmonary Bypass for Lung Transplantation: Is It Safer Than We Think
The use of cardiopulmonary bypass (CPB) during lung transplantation is controversial. CPB can offer improved visualization, better control of central vasculature, and possibly faster operations. Opponents argue the use of CPB results in higher transfusion requirements, increased rates of primary graft dysfunction (PGD), and more complications such as stroke, acute kidney injury (AKI) and renal failure requiring hemodialysis. In the fall of 2020 our program transitioned to performing all lung transplants on CPB.
Source: The Journal of Heart and Lung Transplantation - April 1, 2023 Category: Transplant Surgery Authors: W. Blanding, M. Hill, Z. Hashmi, T. Whelan, L. Paoletti, K. Engelhardt, B. Gibney Tags: (920) Source Type: research
Incidence and Impact of Post-Transplant Stroke on Outcomes Following Orthotopic Heart Transplantation Under the 2018 United States Heart Allocation System: A UNOS Registry Analysis
With the increased rate of temporary mechanical circulatory support utilization after the 2018 heart allocation policy change, we sought to quantitate the clinical trends and impact of post-transplant stroke (PTS) and functional independence on outcomes following orthotopic heart transplant (OHT).
Source: The Journal of Heart and Lung Transplantation - April 1, 2023 Category: Transplant Surgery Authors: Y. Hong, L.V. Huckaby, N.R. Hess, L.A. Ziegler, G.W. Hickey, J.H. Huston, M.A. Mathier, D.M. McNamara, M.E. Keebler, D.J. Kaczorowski Tags: (639) Source Type: research
Platelet Function and Sildenafil Use During Left Ventricular Assist Device Support
Clinical outcome studies have shown that sildenafil is associated with reduced mortality and thrombotic events such as ischemic stroke during contemporary left ventricular assist device (LVAD) support. Sildenafil has anti-platelet properties but its relation to platelet function during LVAD support is uncertain.
Source: The Journal of Heart and Lung Transplantation - April 1, 2023 Category: Transplant Surgery Authors: O. Saeed, M. Farooq, T. Chinnadurai, J. Ramos, S. Patel, P. Chavez, Y. Rochlani, S. Murthy, J. Shin, S. Vukelic, D. Sims, D. Goldstein, U. Jorde Tags: (136) Source Type: research
A Retrospective Study on Gender, LAA Morphology and Stroke Risk
This was a retrospective study to investigate whether gender and LAA size/morphology was a predictor of cerebral vascular events in patients undergoing cardiac surgery. We studied the LAA morphology, and measurements for women and men in an attempt to correlate the different morphologies/sizes with the patient's risk of stroke.
Source: The Journal of Heart and Lung Transplantation - April 1, 2023 Category: Transplant Surgery Authors: K. Sorensen, D. Rodgers, S. Chandra Uppalapati, U. Siddiqi, S. Jain, S. Paluri, A. Madhushanka, K. Sudheendra, K. Johnson, S. Bangaru, K. Ram, D. Hynes, C. Ozcan, L. Lee, G. Kim, V. Jeevanandam Tags: (550) Source Type: research
Colocutaneous Fistula Following Pediatric Bivad Implantation, A Rare but Serious Complication
We present 2 patients who had rare colocutaneous fistulas associated with Berlin Heart EXCOR ® placement.
Source: The Journal of Heart and Lung Transplantation - April 1, 2023 Category: Transplant Surgery Authors: S. Rangu, J. Murray, A. Shiu, E. Martin, T. Nasirov, M. Bruzoni, S. Chen, D. Rosenthal, M. Ma, J. Dykes Tags: (1035) Source Type: research
Successful Bridge From Va-Ecmo to Heart Transplant in an Adult after Mechanical Thrombectomy for Acute Ischemic Stroke
We present a unique case of a patient who underwent MT for acute ischemic stroke while on VA-ECMO with the resolution of neurological deficits and eventually underwent heart transplantation (HT).
Source: The Journal of Heart and Lung Transplantation - April 1, 2023 Category: Transplant Surgery Authors: S. Riaz, M. Hakim, T.V. Mehta, A. Jaiswal, A. Scatola Tags: (777) Source Type: research
Impact of Perioperative Sarcopenia and Dysphagia on LVAD Related Complications
Sarcopenia, as defined by decline in muscle quantity/quality, is prevalent in heart failure and associated with high morbidity and mortality. Sarcopenic dysphagia is caused by sarcopenia in the whole body and swallowing-related muscles. We investigated the impact of perioperative sarcopenia and dysphagia on postoperative pneumonia (PNA), stroke, gastrointestinal bleeding (GIB) and 30-d readmission after LVAD.
Source: The Journal of Heart and Lung Transplantation - April 1, 2023 Category: Transplant Surgery Authors: M. Nishikawa, M.R. Carey, A. Ladanyi, G.M. Mondellini, A. Pinsino, K. Antler, E. Goldberg, J. Hastie, K. Clerkin, G.T. Sayer, N. Uriel, K. Takeda, P.C. Colombo, M. Yuzefpolskaya Tags: (765) Source Type: research
Stroke and Survival Outcomes in Left Ventricular Device Patients
Left ventricular assist devices (LVADs) are artificial pumps used for hemodynamic support in patients with end stage heart failure. They can function effectively as a bridge to transplant as well as extend and improve the quality of life of patients. However, these patients are still at a higher risk of stroke, death, and other complications than the average population.
Source: The Journal of Heart and Lung Transplantation - April 1, 2023 Category: Transplant Surgery Authors: N. Berg, C. Shah, M. Guglin, H. Ferguson Tags: (759) Source Type: research
Estimation of Stroke Risk in Patients with Fabry Disease Using a Machine Learning Model
In this study, the performance of a machine learning platform in estimating FD patients’ 12-month stroke risk was assessed.
Source: The Journal of Heart and Lung Transplantation - April 1, 2023 Category: Transplant Surgery Authors: J. Jefferies, S. Kallish, G. Biondetti, P. Aguiar, M. Nelson, J. Giuliano, J. Zabinksi, C. Boussios, G. Curhan, J. Bandaria, R. Gliklich, D. Warnock Tags: (753) Source Type: research
Right heart failure after left ventricular assist device implantation – from prediction to action
In this issue of the Journal, Read and colleagues1 report the use of peak stroke volume index (SVI) during pre-procedure vasodilatory testing as a predictor of early right heart failure (RHF) after left ventricular assist device (LVAD) implantation. They retrospectively examine 70 patients from three institutions who underwent pre-implant nitroprusside vasodilator testing. Indications for pre-operative vasodilator testing were elevated pulmonary vascular resistance, pulmonary arterial wedge pressure, or systolic pulmonary artery pressure.
Source: The Journal of Heart and Lung Transplantation - August 31, 2022 Category: Transplant Surgery Authors: Sameer K Singh, Koji Takeda Tags: Editorial Source Type: research
Unique Findings of Myocardial Improvement with Lower Left Ventricular Assist Device Pump Speed
Currently, optimizing hemodynamics and unloading in patients with left ventricular assist device (LVAD) relies on echocardiography and right heart catherization guidance for pump speed adjustments. However, the ideal unloading strategy to maximize reverse remodelling is uncertain - whether to provide maximal pump support to unload the heart ( ‘rest’), or maximize ventricular work with partial pump support (‘work’). Using non-invasively derived PV loops, we sought to characterize the longitudinal changes in chamber contractile parameters stroke work (SW), peak systolic pressure (LVPmax) and peak LV elastance (Ees) a...
Source: The Journal of Heart and Lung Transplantation - April 1, 2022 Category: Transplant Surgery Authors: A. Gunawan, D. Robson, A. Ramanayake, R.J. Krishnaswamy, K. Kearney, K. Muthiah, P. Jain, A. Adji, C.S. Hayward Tags: (434) Source Type: research
Central VA-ECMO Support without Full Anticoagulation is Feasible During Lung Transplant
In this study, we analyzed the feasibility of central VA-ECMO without full anticoagulation during lung transplantation. We also analyzed the incidence of morbidity including ischemic and thrombotic complications, stroke, and postoperative outcomes.
Source: The Journal of Heart and Lung Transplantation - April 1, 2022 Category: Transplant Surgery Authors: Y. Yagi, A. Manerikar, A. Bharat, C. Kurihara Tags: (911) Source Type: research
Carotid Endarterectomy Prior to Ventricular Assist Device Placement in a Patient with Cardiogenic Shock
Atherosclerotic disease in the cervical vessels may be a contraindication for implantation of left ventricular assist devices (LVADs). The occurrence of ischemic stroke represents an obstacle to rehabilitation, and its incidence seems to be higher in this population. Carotid endarterectomy (CEA) is a preferable surgical treatment in patients with high bleeding risk. This case report suggests that CEA followed by implantation of LVADs can be feasible.
Source: The Journal of Heart and Lung Transplantation - April 1, 2022 Category: Transplant Surgery Authors: M.S. Lira, R.C. Dantas, D.d. Belfort, S.R. Furquim, C.A. Arag ão, B.R. Gomes, B.S. Biselli, S.M. Ferreira, E.A. Bocchi Tags: (558) Source Type: research
Assessing Cardiac Recovery for Decommissioning of LVAD Support: Structure versus Function
Recovery of left ventricular (LV) function during LVAD support occurs in only 1-3% of patients. Assessment for recovery and LVAD removal is desirable given the risks of infection, stroke, and device malfunction. This case of a patient with an LVAD, with recovered LV systolic function but abnormal exercise hemodynamics, illustrates the potential utility of right heart catheterization studies for clinical decisions.
Source: The Journal of Heart and Lung Transplantation - April 1, 2022 Category: Transplant Surgery Authors: R.S. Gabarin, V. Gurtu, D.H. Brahmbhatt, F. Billia, S. Mak Tags: (550) Source Type: research
