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Source: The Journal of Heart and Lung Transplantation

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Total 231 results found since Jan 2013.

The Effect of Race on Stroke Incidence and Post-Stroke Mortality - The Stroke Paradox in LVAD Patients
Stroke is considered one of the major hurdles in applying Left Ventricular Assist Device (LVAD) technology to a broader population, and remains a leading cause of mortality and morbidity despite advances in both technology and management. In the general population, incidence of stroke in African Americans (AA) has been reported to be twice that of their Caucasian counterparts, and the mortality following stroke higher in AA. We sought to assess the effect of race on both rate of stroke, as well as post stroke survival in the LVAD population.
Source: The Journal of Heart and Lung Transplantation - March 31, 2020 Category: Transplant Surgery Authors: S.D. Rao, V. Troung, E. Chung, W.S. Mazur, D. Goldstien, U.P. Jorde, J. Teuteberg, S.R. Messe, C.S. Hayward, G.F. Egnaczyk, M.A. Acker, S.S. Sreenivas, J.E. Rame Tags: (212) Source Type: research

Blood pressure and stroke risk in left ventricular assist devices
Ischemic and hemorrhagic stroke are one of the most devastating outcomes arising from treatment of end-stage congestive heart failure with a left ventricular assist device (LVAD)1. Stroke after LVAD is associated with increased risk of mortality and is a leading cause of not qualifying for transplantation. The risk of stroke is one of many factors limiting more widespread adoption of this technology for end-stage heart failure. The risk factors for stroke in LVAD have been the subject of several studies, with recent infection2 and changes in anti-thrombotics being commonly found3.
Source: The Journal of Heart and Lung Transplantation - December 5, 2014 Category: Transplant Surgery Authors: Joshua Z. Willey Source Type: research

The ABC's of Stroke Prevention: Reduction in Stroke Frequency Following a Quality Improvement Intervention by the Action Learning Network
To assess the frequency of stroke among ventricular assist device patients following a quality improvement bundled intervention (the “ABCs of Stroke Prevention” [ABCs] which focused on Anticoagulation, Blood pressure, and Communication) within the Advanced Cardiac Therapies Improving Outcomes Network (ACTION). The bundle intervention comprised 3 interventions. These were: a document harmonizing how to implement and maintain b ivalirudin infusion, a blood pressure management protocol and a daily stroke prevention checklist.
Source: The Journal of Heart and Lung Transplantation - March 20, 2021 Category: Transplant Surgery Authors: J. Murray, D. Rosenthal, F. Zafar, A. Lorts, C. Connelly, P. Krack, C. Vanderpluym, B. Hawkins, R. Niebler, M. Mehegan, R. Gajarski, D. Sutcliffe, C. Villa Tags: (168) Source Type: research

Elevated Blood Pressure Before Left Ventricular Assist Device Support Implant is Associated with an Increased Risk of Stroke
Despite the recent advances in Left Ventricular Assist Device (LVAD) therapy, stroke remains a frequent and catastrophic complication. Hypertension (HTN) after LVAD implant has been associated with an increased risk of stroke, but the association between HTN before LVAD implant and stroke has never been studied. We hypothesized that LVAD patients with elevated blood pressure (BP) during outpatient visits before the LVAD implant may have an increased risk of stroke.
Source: The Journal of Heart and Lung Transplantation - March 20, 2021 Category: Transplant Surgery Authors: F. Castagna, S. Patel, S. Vukelic, S. Madan, O. Saeed, D. Sims, D. Goldstin, U.P. Jorde Tags: (978) Source Type: research

Systolic Blood Pressure on Discharge after Left Ventricular Assist Device Insertion is Associated with Subsequent Stroke
Stroke is a significant complication in patients supported with continuous-flow left ventricular assist devices (CF-LVAD) and hypertension (HTN) is a significant risk factor for stroke, but the association between blood pressure and stroke in LVAD patients is not well characterized.
Source: The Journal of Heart and Lung Transplantation - October 22, 2014 Category: Transplant Surgery Authors: Michael E. Nassif, Anjan Tibrewala, David S. Raymer, Adam Andruska, Eric Novak, Justin M. Vader, Akinobu Itoh, Scott C. Silvestry, Gregory A. Ewald, Shane J. LaRue Source Type: research

Stroke Subtype Impacts Outcomes and Transplant Eligibility in CF-LVADS
We present a large single center experience on stroke outcome and transplant eligibility by stroke subtype in CF-LVAD pts.
Source: The Journal of Heart and Lung Transplantation - April 1, 2015 Category: Transplant Surgery Authors: J.Z. Willey, M. Gavalas, A. Levin, A. Breskin, V.K. Topkara, M. Yuzefpolskaya, K. Orlanes, M.R. Torres, M. Tiburcio, K. Ross, R.A. Garan, K. Wong, U.P. Jorde, D.M. Mancini, K. Takeda, H. Takayama, Y. Naka, P.C. Colombo Source Type: research

Outcomes After Stroke Complicating Left Ventricular Assist Device
We present a large single center experience on stroke outcome and transplant eligibility by stroke subtype and severity in CF-LVAD patients.
Source: The Journal of Heart and Lung Transplantation - March 29, 2016 Category: Transplant Surgery Authors: Joshua Z. Willey, Michael V. Gavalas, Pauline N. Trinh, Melana Yuzefpolskaya, A. Reshad Garan, Allison P. Levin, Koji Takeda, Hiroo Takayama, Justin Fried, Yoshifumi Naka, Veli K. Topkara, Paolo C. Colombo Source Type: research

Outcomes after stroke complicating left ventricular assist device
We present a large single-center experience on stroke outcome and transplant eligibility by stroke sub-type and severity in CF-LVAD patients.
Source: The Journal of Heart and Lung Transplantation - March 29, 2016 Category: Transplant Surgery Authors: Joshua Z. Willey, Michael V. Gavalas, Pauline N. Trinh, Melana Yuzefpolskaya, A. Reshad Garan, Allison P. Levin, Koji Takeda, Hiroo Takayama, Justin Fried, Yoshifumi Naka, Veli K. Topkara, Paolo C. Colombo Tags: Original Clinical Science Source Type: research

Risk Predictors for Ischemic Stroke in CF-LVAD Patients by Pump Flow Type
Risk of stroke continues to be a major adverse event post-LVAD implantation, limiting wider application and utility of the device. Even with aggressive blood pressure control, patients with LVADs are at higher risk of stroke due to combination of pump-dependent factors including loss of natural pulsatility, anticoagulation, and thrombosis risk from blood-pump interaction. We used a Bayesian Network machine-learning approach to derive comparative risk factors for ischemic stroke in patients with axial versus centrifugal flow pumps at 3 months post LVAD implant.
Source: The Journal of Heart and Lung Transplantation - March 31, 2018 Category: Transplant Surgery Authors: M. Kanwar, L. Lohmueller, R. Kormos, S. Bailey, C. Mcilvennan, S. Murali, J. Antaki Source Type: research

Carotid Artery Blood Flow and Its Association with Stroke during Left Ventricular Assist Device Support
Left ventricular assist device (LVAD) surgery is a life-prolonging therapy for advanced heart failure (HF). Despite many improvements over the years, LVADs continue to be associated with a high incidence of stroke and other vascular complications such as gastrointestinal bleeding (GIB). At present, the pathogenesis of these complications during LVAD support remains unclear. Abnormal structure and hemodynamics in large arteries are a potential contributor. We hypothesized that structural abnormalities and flow alterations will be significantly associated with stroke and a composite outcome of stroke, GIB, and death in HF pa...
Source: The Journal of Heart and Lung Transplantation - March 16, 2019 Category: Transplant Surgery Authors: M.E. Kiyatkin, A.M. Zuver, A. Gaudig, M. Tiburcio, B.J. McDonnell, M. Yuzefpolskaya, P.C. Colombo, E.J. St öhr, J.Z. Willey Tags: 401 Source Type: research

Occurrence and Clinical Patterns of Stroke Based on Arterial Cannulation Strategy during Veno-Arterial Extracorporeal Membrane Oxygenation Support
Stroke is a major complication with potentially devastating consequences for patients receiving veno-arterial extracorporeal membrane oxygenation (VA-ECMO). Arterial cannulation sites for VA-ECMO include ascending aorta, axillary artery, and femoral artery. However, rates of stroke according to cannulation site are currently unknown. The purpose of this study was to investigate the association between occurrence and patterns of stroke with ECMO arterial cannulation sites.
Source: The Journal of Heart and Lung Transplantation - March 16, 2019 Category: Transplant Surgery Authors: M. Nishikawa, J. Willey, A.R. Garan, M. Cevasco, L. Witer, J. Sanchez, P. Kurlansky, A. Kirtane, D. Brodie, M. Yuzefpolskaya, P. Colombo, H. Takayama, Y. Naka, K. Takeda Tags: 148 Source Type: research

Incidence, Predictors and Outcomes of Stroke Following Cardiac Transplantation
Stroke after heart transplantation (HT) is a major cause of morbidity and mortality. Less is known about the risk factors associated with stroke in the current era of increasing HT being performed in older patients and with advances in immunosuppressive (IS) therapies. We aimed to determine the incidence, predictors and outcomes of stroke after HT.
Source: The Journal of Heart and Lung Transplantation - March 20, 2021 Category: Transplant Surgery Authors: H. Alnsasra, R. Asleh, N. Kumar, T. Toya, C. Lopez, W.K. Kremers, B. Edwards, R.C. Daly, S.S. Kushwaha Tags: (548) Source Type: research

Increased Nocturnal Arterial Stiffness is Associated with a Higher Risk of Stroke in LVAD Patients
In this study, we aimed to investigate whether increased arterial stiffness is associated with a higher risk of stroke in LVAD patients.
Source: The Journal of Heart and Lung Transplantation - April 1, 2022 Category: Transplant Surgery Authors: F. Castagna, G.M. Mondellini, B. McDonnell, A. Pinsino, M. Tiburcio, M. Pineda, K. Takeda, Y. Naka, A. Ladanyi, G.T. Sayer, N. Uriel, M. Yuzefpolskaya, J.Z. Willey, G. Parati, J. Cockcroft, P.C. Colombo Tags: (1148) Source Type: research

Successful Bridge From Va-Ecmo to Heart Transplant in an Adult after Mechanical Thrombectomy for Acute Ischemic Stroke
We present a unique case of a patient who underwent MT for acute ischemic stroke while on VA-ECMO with the resolution of neurological deficits and eventually underwent heart transplantation (HT).
Source: The Journal of Heart and Lung Transplantation - April 1, 2023 Category: Transplant Surgery Authors: S. Riaz, M. Hakim, T.V. Mehta, A. Jaiswal, A. Scatola Tags: (777) Source Type: research

Estimation of Stroke Risk in Patients with Fabry Disease Using a Machine Learning Model
In this study, the performance of a machine learning platform in estimating FD patients’ 12-month stroke risk was assessed.
Source: The Journal of Heart and Lung Transplantation - April 1, 2023 Category: Transplant Surgery Authors: J. Jefferies, S. Kallish, G. Biondetti, P. Aguiar, M. Nelson, J. Giuliano, J. Zabinksi, C. Boussios, G. Curhan, J. Bandaria, R. Gliklich, D. Warnock Tags: (753) Source Type: research