Cerebral Vasoreactivity in HeartMate 3 Patients

While rates of stroke have declined with the HeartMate3 (HM3) continuous flow (CF) left ventricular assist device (LVAD), the impact of non-pulsatile flow and artificial pulse physiology on cerebrovascular function is not known. We hypothesized that improved hemodynamics and artificial pulse physiology of HM3 patients would augment cerebrovascular metabolic reactivity (CVR) compared with HeartMate II (HMII) CF-LVAD and heart failure (HF) patients.

Source: The Journal of Heart and Lung Transplantation - May 21, 2021 Category: Transplant Surgery Authors: Eric J. St öhr, Ruiping Ji, Koichi Akiyama, Giulio Mondellini, Lorenzo Braghieri, Alberto Pinsino, John R. Cockcroft, Melana Yuzefpolskaya, Amrin Amlani, Veli K. Topkara, Hiroo Takayama, Yoshifumi Naka, Nir Uriel, Koji Takeda, Paolo C. Colombo, Barry J. Tags: Original Research Article Source Type: research