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Source: Journal of Neurology
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Total 399 results found since Jan 2013.
Misjudgment of pre-stroke functional status contradicts beneficial outcomes after endovascular therapy for large vessel occlusion
In conclusion, thorough pre-EVT assessment of pre-stroke functional status appears decisive for proper selection of EVT candidates.
Source: Journal of Neurology - July 18, 2019 Category: Neurology Source Type: research
Vestibular symptoms in acute hemispheric strokes
In conclusion, cerebral hemispheric infarction limited to the PIVC or TPSVC does not necessarily cause vertigo. However, unilateral hemispheric infarctions, restricted to the areas belonging to the vestibular cortical network may cause vestibul ar symptoms. The lesions responsible for vestibular symptoms are located more often in the right hemisphere.
Source: Journal of Neurology - July 18, 2019 Category: Neurology Source Type: research
Influence of procedure time on outcome and hemorrhagic transformation in stroke patients undergoing thrombectomy
ConclusionsThe PT is an independent predictor for 90-day outcomes in stent-retriever thrombectomy patients. Postprocedural HT was partially responsible for the worse outcome in patients who experienced a longer PT.
Source: Journal of Neurology - July 2, 2019 Category: Neurology Source Type: research
Selection of anterior circulation acute stroke patients for mechanical thrombectomy
ConclusionsTVSS is a reliable tool for selection of AIS candidates for MT and optimization of transfer to comprehensive stroke centers.
Source: Journal of Neurology - July 2, 2019 Category: Neurology Source Type: research
Thrombocytopenia and declines in platelet counts: predictors of mortality and outcome after mechanical thrombectomy
ConclusionIn AIS patients treated with MT an initial TP was independently associated with higher mortality rates and a marked DPC with higher mortality rates as well as poorer clinical outcomes.
Source: Journal of Neurology - June 20, 2019 Category: Neurology Source Type: research
Intra-arterial thrombectomy for acute ischaemic stroke patients with active cancer
ConclusionsAlthough baseline characteristics and recanalisation rate after IAT up to 24 h after stroke onset were similar between acute ischaemic stroke patients with active cancer and without any cancer, stroke-related death and short-term outcome were significantly poorer in patients with active cancer than the controls. Post-procedural haemorrhage and active cancer itself were ind ependent predictors of a decrease in functional independence at 3 months.
Source: Journal of Neurology - June 6, 2019 Category: Neurology Source Type: research
Stroke severity in patients with preceding direct oral anticoagulant therapy as compared to vitamin K antagonists
AbstractBackgroundAlthough direct oral anticoagulants (DOAC) have proven at least equally effective in the prevention of acute ischemic stroke (AIS) in patients with atrial fibrillation as compared to the vitamin K antagonists (VKA), no reliable data on the severity of AIS of DOAC patients as compared to VKA is available.MethodsUsing a prospectively collected cohort of AIS patients, we performed univariate and multivariate (displayed as adjusted Odds Ratios, OR and 95% confidence intervals, 95% CI) analyses regarding the severity of AIS in patients with preceding DOAC (N = 210) versus VKA (N = 173) therapy. Additio...
Source: Journal of Neurology - June 3, 2019 Category: Neurology Source Type: research
Thrombus hallmarks reveal atherothrombotic stroke aetiology
Source: Journal of Neurology - May 14, 2019 Category: Neurology Source Type: research
A cluster of disseminated small cortical lesions in MELAS: its distinctive clinical and neuroimaging features
ConclusionsThis study showed a diversity of SLEs in patients with m.3243A>G mutation. Further studies are required to elucidate the pathophysiological mechanisms of non-classic SLEs including D-SLEs.
Source: Journal of Neurology - May 14, 2019 Category: Neurology Source Type: research
Risk factors for in-hospital and follow-up mortality after childhood arterial ischemic stroke
ConclusionsThis study identified groups with greater acute and long-term mortality after a first episode of AIS in childhood. Specific interventions focused on these risk groups may decrease mortality rates. Further studies need to confirm our findings by adding children from other centers.
Source: Journal of Neurology - May 14, 2019 Category: Neurology Source Type: research
Specific mechanisms of subarachnoid hemorrhage accompanied by ischemic stroke in essential thrombocythemia: two case reports and a literature review
ConclusionsThe current study describes rare cases of SAH accompanied by ischemic stroke secondary to ET along with a review of the current literature, implying specific mechanisms for cerebral artery disorders associated withJAK2 V617F mutation.
Source: Journal of Neurology - May 1, 2019 Category: Neurology Source Type: research
Misdiagnoses and delay of diagnoses in Moyamoya angiopathy —a large Caucasian case series
ConclusionsThis is the first systematic report which shows that patients with MMA are at high risk to be falsely diagnosed and treated. Depiction of typical vascular abnormalities in angiopathy is essential. Normal CSF cell counts, negative oligoclonal bands, and lack of infratentorial lesions as well as gadolinium-positive T1 lesions on MRI may be red flags differentiating this vasculopathy from vasculitis and MS.
Source: Journal of Neurology - April 16, 2019 Category: Neurology Source Type: research
Prevalence and risk factors of stroke in the elderly in Northern China: data from the National Stroke Screening Survey
AbstractBackgroundThe overall global burden of stroke is considerable and increasing. In China, stroke is the leading cause of death and disability.MethodsFor this study, we used data from the National Stroke Screening Survey in 2012 and the 2010 Chinese population from sixth National Census of Populations to calculate a standardized (by age, gender, and education) stroke prevalence. Prevalence, risk factors, and management of stroke were compared by gender, age, and site.FindingsThe standardized prevalence rate of survival stroke patients in study population aged 60 and older was 4.94% in total. Hypertension was the most ...
Source: Journal of Neurology - April 14, 2019 Category: Neurology Source Type: research
Occurrence of cerebral small vessel disease at diagnosis of MPO-ANCA-associated vasculitis
ConclusionInflammatory events are associated with the occurrence of cerebral SVD before clinical diagnosis of MPO-ANCA-positive AAV. The patients may be continuously exposed to the risk of cerebral SVD after immunosuppressive therapy.
Source: Journal of Neurology - April 12, 2019 Category: Neurology Source Type: research
Clinical presentation of Moyamoya angiopathy in Europeans: experiences from Germany with 200 patients
ConclusionsCompared with Asian data, cerebral hemorrhages are infrequent and female predominance is accentuated among European Caucasians. Some former unknown rare features like associated livedo racemosa, dysgenesis of corpus callosum and associated syncope have been discovered systematically for the first time in this huge European Caucasian cohort.
Source: Journal of Neurology - March 12, 2019 Category: Neurology Source Type: research
