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Source: Journal of Neurology

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Total 399 results found since Jan 2013.

Incidence, prevalence and disability associated with neurological disorders in Italy between 1990 and 2019: an analysis based on the Global Burden of Disease Study 2019
ConclusionsThe increase in YLDs associated with neurological conditions is mostly due to population ageing and growth: nevertheless, lived disability and, as a consequence, impact on health systems has increased. Actions are needed to improve outcome and mitigate disability associated with neurological conditions, spanning among diagnosis, treatment, care pathways and workplace interventions.
Source: Journal of Neurology - September 8, 2021 Category: Neurology Source Type: research

Acute transverse myelitis following SARS-CoV-2 vaccination: a case report and review of literature
ConclusionTo our knowledge, this is the one of early reported case of transverse myelitis and with post SARS-CoV-2 vaccination, who responded well to plasmapheresis. Further studies would be recommended to identify the underlying correlation between COVID-19 vaccination and transverse myelitis.
Source: Journal of Neurology - September 5, 2021 Category: Neurology Source Type: research

Detection of large vessel occlusion stroke with electroencephalography in the emergency room: first results of the ELECTRA-STROKE study
ConclusionDry electrode EEG is a promising tool for LVO-a stroke detection, but data quality needs to be improved and validation in the prehospital setting is necessary. (TRN: NCT03699397, registered October 9 2018).
Source: Journal of Neurology - September 2, 2021 Category: Neurology Source Type: research

Correction to: Long-term psychosocial outcome following mild traumatic brain injury and minor stroke: a direct longitudinal comparison
Source: Journal of Neurology - September 1, 2021 Category: Neurology Source Type: research

Decrease in intravenous thrombolysis and poor short-term functional prognosis for acute ischemic stroke during the COVID-19 pandemic
ConclusionsThe COVID-19 pandemic caused the decrease of admissions and prolonged the time of the green channel for stroke, which led to the worse short-term prognosis of AIS patients during the pandemic. It ’s necessary to ensure an effective green channel and provide adequate medical resources during the pandemic period to reduce the damage caused by COVID-19.
Source: Journal of Neurology - August 11, 2021 Category: Neurology Source Type: research

Neurological manifestations of patients infected with the SARS-CoV-2: a systematic review of the literature
ConclusionThis updated review of literature, shows that headache, skeletal muscle injury, psychiatric disorders, impaired consciousness, and gustatory/olfactory dysfunction were the most common neurological symptoms of COVID-19 patients. Impaired consciousness and acute cerebrovascular events were significantly higher among patients with a severe infection. AIS patients required ICU admission in 63% of cases, while intra-hospital mortality rate was close to 23%.
Source: Journal of Neurology - July 19, 2021 Category: Neurology Source Type: research

Frequency of silent brain infarction in transient global amnesia
ConclusionsIn a relevant proportion of clinical TGA patients, MRI reveals acute ischemic cerebral lesions. Therefore, cerebral MRI should be performed in patients with TGA to identify a possible cardiac involvement and to detect stroke chameleons.
Source: Journal of Neurology - July 17, 2021 Category: Neurology Source Type: research

Risk of intracranial haemorrhage and ischaemic stroke after convexity subarachnoid haemorrhage in cerebral amyloid angiopathy: international individual patient data pooled analysis
ConclusionsPatients with cSAH associated with probable or possible CAA have high risk of future ICH and recurrent cSAH. Convexity SAH associated with probable (vs possible) CAA is associated with increased risk of ICH, and cSAH but not ischemic stroke. Our data provide precise risk estimates for key vascular events after cSAH associated with CAA which can inform management decisions.
Source: Journal of Neurology - July 17, 2021 Category: Neurology Source Type: research

Acute vestibular syndrome: is skew deviation a central sign?
ConclusionsContrary to prior knowledge, skew deviation proved to be more prevalent in patients with AVS and occurred in every forth patient with AUVP. Large skew deviations (>  3.3 deg), were pointing toward a central lesion. Clinical and video test of skew offered little additional diagnostic value compared to other diagnostic tests such as the head impulse test and nystagmus test. Video test of skew could aid to quantify skew in the ED setting in which neurotological expertise is not always readily available.
Source: Journal of Neurology - July 9, 2021 Category: Neurology Source Type: research

Cystatin C predicts futile recanalization in patients with acute ischemic stroke after endovascular treatment
ConclusionsA higher level of cystatin C is associated with unfavourable outcomes at 3  months in anterior circulation acute ischaemic stroke patients with endovascular thrombectomy.
Source: Journal of Neurology - July 5, 2021 Category: Neurology Source Type: research

MRI radiomic features-based machine learning approach to classify ischemic stroke onset time
ConclusionsA unique deep learning model based on DWI/ADC radiomic features was constructed for TSS classification, which could aid in decision making for thrombolysis in patients with unknown stroke onset.
Source: Journal of Neurology - July 4, 2021 Category: Neurology Source Type: research

Stroke care in Italy at the time of the COVID-19 pandemic: a lesson to learn
AbstractFrom March to May 2020, the Italian health care system, as many others, was almost entirely devoted to the fight against the COVID-19 pandemic. In this context, a number of questions arose, from the increased stroke risk due to COVID-19 infection to the quality of stroke patient care. The overwhelming need of COVID-19 patient management made mandatory a complete re-organization of the stroke pathways: many health professionals were reallocated and a number of stroke units was turned into COVID-19 wards. As a result, acute stroke care suffered from a shortage of services and delays in time-dependent treatments and d...
Source: Journal of Neurology - June 21, 2021 Category: Neurology Source Type: research

The Clock Drawing Test as a predictor of cognitive decline in non-demented stroke patients
ConclusionA bedside cognitive screening with the CDT helps identifying patients at higher risk of PSCI.
Source: Journal of Neurology - June 6, 2021 Category: Neurology Source Type: research

Altered mental status in COVID-19
ConclusionIn patients with COVID-19, AMS on presentation to the ED is most frequently caused by metabolic encephalopathy (delirium). Seizures and cerebrovascular events contribute to a lesser degree; encephalitis appears rare.
Source: Journal of Neurology - June 3, 2021 Category: Neurology Source Type: research

Impact of the COVID-19 lockdown on the adherence of stroke patients to direct oral anticoagulants: a secondary analysis from the MAAESTRO study
ConclusionOur data suggest that a major disruption of social life (i.e., the imposed COVID-19 lockdown) is unlikely to relevantly affect the medication intake behaviour of patients with high pre-established adherence, but might have an impact in patients with previously suboptimal adherence.Trial registration numberMAAESTRO: electronic Monitoring and improvement of Adherence to direct oral Anticoagulant treatment —a randomized crossover study of an Educational and reminder-based intervention in ischaemic STROke patients under polypharmacy, NCT03344146.
Source: Journal of Neurology - June 3, 2021 Category: Neurology Source Type: research