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Source: Journal of Neurology
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Total 399 results found since Jan 2013.
Effect of small-vessel disease on cognitive trajectory after atrial fibrillation-related ischaemic stroke or TIA
AbstractPost-stroke dementia is common but has heterogenous mechanisms that are not fully understood, particularly in patients with atrial fibrillation (AF)-related ischaemic stroke or TIA. We investigated the relationship between MRI small-vessel disease markers (including a composite cerebral amyloid angiopathy, CAA, score) and cognitive trajectory over 12 months. We included patients from the CROMIS-2 AF study without pre-existing cognitive impairment and with Montreal Cognitive Assessment (MoCA) data. Cognitive impairment was defined as MoCA< 26. We defined “reverters” as patients with an “acute” MoCA (...
Source: Journal of Neurology - March 6, 2019 Category: Neurology Source Type: research
Cerebral microbleeds are associated with cognitive decline early after ischemic stroke
ConclusionCognitive abilities are more severely impaired in CMB-positive stroke patients compared to CMB-free controls, whereby memory-associated functions are most affected. CMB might be associated with post-stroke cognitive decline, particularly with impaired memory and phonemic fluency.
Source: Journal of Neurology - February 14, 2019 Category: Neurology Source Type: research
Anger, hostility and risk of stroke: a meta-analysis of cohort studies
ConclusionA higher level of anger and hostility is not associated with elevated risk of stroke. However, the association is positive among people with lower socioeconomic status.
Source: Journal of Neurology - February 11, 2019 Category: Neurology Source Type: research
Early microvascular cerebral blood flow response to head-of-bed elevation is related to outcome in acute ischemic stroke
ConclusionsEarly CBF response to mild HOB elevation in the ipsilesional hemisphere is related to functional outcome. Further studies may enable optical monitoring at the bedside to individualize management strategies in the early phase of AIS.
Source: Journal of Neurology - February 9, 2019 Category: Neurology Source Type: research
Pre-treatment cerebral microbleeds and intracranial hemorrhage in patients with ischemic stroke receiving endovascular therapy: a systematic review and meta-analysis
ConclusionsThere is no evidence that pre-treatment CMBs were associated with an increased incidence of ICH in patients with ischemic stroke receiving EVT.
Source: Journal of Neurology - January 28, 2019 Category: Neurology Source Type: research
Incidence and mechanism of early neurological deterioration after endovascular thrombectomy
ConclusionNeurological deterioration frequently occurs after endovascular thrombectomy, and the risk factors of END differ according to the mechanism of END.
Source: Journal of Neurology - January 10, 2019 Category: Neurology Source Type: research
Long-lasting diagonistic dyspraxia suppressed by rTMS applied to the right motor cortex
We describe the case of a 58-year-old patient with complete callosal agenesis, who developed after a stroke a long lasting and distressing diagonistic dyspraxia. We found two original treatments to relieve the patient from his left limb conflicting movements. Reinforcing left arm sensory input minimized dyspraxic movements but was difficult to apply daily and was found unsatisfactory by the patient. As left anarchic, unwished movements of diagonistic dyspraxia have been attributed to the lack of inhibition exerted by supplementary motor area on right motor cortex, we applied sham-controlled rTMS to the right motor cortex. ...
Source: Journal of Neurology - January 10, 2019 Category: Neurology Source Type: research
Outcomes after stenting for symptomatic intracranial arterial stenosis: a systematic review and meta-analysis
ConclusionThis systematic review provided the worldwide profile of short- and long-term outcomes of stenting for symptomatic ICAS. The generally acceptable outcomes indicate that stenting may still be feasible in selected patients. Regional disparity calls for more cautious decisions and future studies.
Source: Journal of Neurology - January 5, 2019 Category: Neurology Source Type: research
Determining factors of better leptomeningeal collaterals: a study of 857 consecutive acute ischemic stroke patients
ConclusionsYounger age, dyslipidemia and lower creatinine levels were predictors of better collaterals in AIS patients from proximal MCA occlusions. Greater degree of collaterals related to lower stroke severity on admission. On neuroimaging, better collaterals were independently associated with minor early ischemic changes and lower clot burden. These data may add knowledge on pathophysiology of collaterals development and may help to identify patients with better collaterals for late or aggressive recanalization treatments.
Source: Journal of Neurology - January 4, 2019 Category: Neurology Source Type: research
Impact of virtual reality-based rehabilitation on functional outcomes in patients with acute stroke: a retrospective case-matched study
ConclusionsThis study suggests that the combination of VR-based rehabilitation and traditional therapy could be more effective for neurorehabilitation than CT alone in the early improvement of symptom severity, functional outcomes, and lower medical expenditure in acute stroke patients.
Source: Journal of Neurology - January 4, 2019 Category: Neurology Source Type: research
Moyamoya angiopathy: long-term follow-up study in a Finnish population
ConclusionsFinnish MMA patients have a benign and stable course with a ~3.5 % annual stroke risk. We found no differences in the clinical outcomes between the operated and conservative groups, however, the psychosocial well-being requires more attention in MMA patients.
Source: Journal of Neurology - December 17, 2018 Category: Neurology Source Type: research
Pretreatment cerebral microbleeds and symptomatic intracerebral hemorrhage post-thrombolysis: a systematic review and meta-analysis
ConclusionsThe pretreatment CMBs were associated with increased incidence of sICH and PFO in acute ischemic stroke patients receiving IVT. However, it was not convincing enough to set the presence of CMBs as contraindication to IVT.
Source: Journal of Neurology - December 12, 2018 Category: Neurology Source Type: research
Clinical feasibility of 1-min ultrafast brain MRI compared with routine brain MRI using synthetic MRI: a single center pilot study
ConclusionsAlthough the overall image quality and anatomical delineation of the 1-min ultrafast MRI were inferior to those of the routine brain MRI protocol, the ultrafast protocol showed at least sufficient image quality. Therefore, this protocol may be an option in specific clinical situations involving non-cooperative, restless, or pediatric patients, or patients with time-critical disease such as stroke. Further study is required to validate our findings.
Source: Journal of Neurology - December 7, 2018 Category: Neurology Source Type: research
Guillain –Barré syndrome in Denmark: a population-based study on epidemiology, diagnosis and clinical severity
ConclusionThe epidemiology and full clinical spectrum of GBS are described in a population-based study. This includes a larger proportion of milder cases that are underrepresented in prospective cohorts such as IGOS.
Source: Journal of Neurology - December 7, 2018 Category: Neurology Source Type: research
A closer look at ping-pong gaze: an observational study and literature review
ConclusionsPPG is a sign with localizing value that suggests hemispheric damage and asymmetric PPG might help to predict lateralization of the lesions. Acute ischemic stroke is the most common cause of PPG. Etiology and initial outcome are likely important prognostic factors of PPG.
Source: Journal of Neurology - November 14, 2018 Category: Neurology Source Type: research
