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Source: Journal of Neurology
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Total 399 results found since Jan 2013.
White matter hyperintensities are an independent predictor of cognitive decline 3 years following first-ever stroke —results from the PROSCIS-B study
ConclusionHigher WMH burden was associated with a significant decline in cognition 3 years post-stroke in this cohort of first-ever stroke patients.
Source: Journal of Neurology - December 6, 2022 Category: Neurology Source Type: research
A rare cause of monogenic cerebral small vessel disease and stroke: Cathepsin A-related arteriopathy with strokes and leukoencephalopathy (CARASAL)
ConclusionsCARASAL should be considered in patients with early onset or severe cerebral small vessel disease, particularly where there are prominent symptoms or signs related to brainstem involvement, such as hearing dysfunction, tinnitus or dysphagia or where there is significant thalamic and brainstem involvement on imaging.
Source: Journal of Neurology - October 31, 2022 Category: Neurology Source Type: research
Transcranial direct current stimulation in neglect rehabilitation after stroke: a systematic review
AbstractHemispatial neglect is one of the most frequent attention disorders after stroke. The presence of neglect is associated with longer hospital stays, extended rehabilitation periods, and poorer functional recovery. Transcranial direct current stimulation (tDCS) is a new technique with promising results in neglect rehabilitation; therefore, the objective of this systematic review, performed following the PRISMA guidelines, is to evaluate the effectiveness of tDCS on neglect recovery after stroke. The search was done in MEDLINE (PubMed), Web of Science, Scopus, Cochrane Library, and BioMed Central databases. A total of...
Source: Journal of Neurology - October 31, 2022 Category: Neurology Source Type: research
Clinical and neuroimaging risk factors associated with the development of intracerebral hemorrhage while taking direct oral anticoagulants
ConclusionsRisk factors including diabetes, prior stroke, and smoking history as well as MRI biomarkers including CMBs and cSS are associated with ICH in DOAC users. Although screening MRIs are not typically performed prior to initiating DOAC therapy, these data suggest that patients of high-hemorrhagic risk may be identified.
Source: Journal of Neurology - October 31, 2022 Category: Neurology Source Type: research
Video augmented mirror therapy for upper extremity rehabilitation after stroke: a randomized controlled trial
ConclusionOur results suggested that mirror therapy using a video augmented wearable reflection device is more efficient compared to traditional mirror therapy for patients with stroke.Clinical trial registration unique identifierKCT0003047.
Source: Journal of Neurology - October 10, 2022 Category: Neurology Source Type: research
Prevalence, risk factors, and clinical outcomes of remote intracerebral hemorrhage after intravenous thrombolysis in acute ischemic stroke: a systematic review and meta-analysis
ConclusionsAlthough rICH is uncommon after intravenous thrombolysis, its presence can lead to worse functional outcomes and higher mortality in acute ischemic stroke. Patients at high risk of rICH must be identified based on potential risk factors.
Source: Journal of Neurology - October 5, 2022 Category: Neurology Source Type: research
Endovascular thrombectomy with or without intravenous alteplase in acute stroke: a systematic review and meta-analysis of randomized clinical trials
ConclusionsNo statistical difference was found in functional and safety outcomes between direct EVT and bridging therapy groups in acute stroke within 4.5 h after symptom onset. EVT alone was non-inferior to bridging therapy for several, but not the more stringent, non-inferiority margins.
Source: Journal of Neurology - October 5, 2022 Category: Neurology Source Type: research
Thrombolysis in stroke patients with elevated inflammatory markers
ConclusionIn IVT-treated patients, leukocytosis independently predicted poor functional outcome and death. Bleeding complications after IVT were not independently associated with leukocytosis.
Source: Journal of Neurology - September 13, 2022 Category: Neurology Source Type: research
Initial symptoms of vertebrobasilar artery occlusions and the outcomes after endovascular treatment
ConclusionWe identified four distinctive subtypes based on the initial symptoms of VBAO patients. Severe VBAO symptoms were associated with poor outcomes while non-specific and vestibular symptoms were indicators of a favourable outcome.
Source: Journal of Neurology - September 13, 2022 Category: Neurology Source Type: research
Correction to: Comparing characteristics and outcomes of in-hospital stroke and community-onset stroke
Source: Journal of Neurology - September 13, 2022 Category: Neurology Source Type: research
Serum glial fibrillary acidic protein is sensitive to acute but not chronic tissue damage in cerebral small vessel disease
ConclusionssGFAP is increased in patients with CSVD-related stroke and correlates with the size of the RSSI. However, sGFAP levels were not related to chronic neuroimaging features or progression of CSVD, suggesting that sGFAP is sensitive to acute but not chronic cerebrovascular tissue changes in this condition.
Source: Journal of Neurology - September 3, 2022 Category: Neurology Source Type: research
A score to predict the stroke recurrence of patients with embolic stroke of undetermined source
ConclusionThe developed score can improve risk stratification after ESUS in secondary care settings.
Source: Journal of Neurology - August 4, 2022 Category: Neurology Source Type: research
Capturing nystagmus in the emergency room: posterior circulation stroke versus acute vestibular neuritis
ConclusionNystagmus is often absent in PCS and always present in AVN. Unidirectional ‘peripheral-appearing’ horizontal nystagmus can be seen in PCS. ER-based VNG nystagmus assessment could provide useful diagnostic information when separating PCS from AVN.
Source: Journal of Neurology - July 18, 2022 Category: Neurology Source Type: research
Acute symptomatic seizures and hippocampal sclerosis: the major contributor for post-stroke epilepsy?
AbstractObjectiveHippocampal sclerosis (HS) is a prominent biomarker of epilepsy. If acquired later in life, it usually occurs in the context of degenerative or acute inflammatory-infectious disease. Conversely, acute symptomatic seizures (ASS) are considered a risk factor for developing post-stroke epilepsy, but other factors remain unrecognized. Here, we hypothesize that silent hippocampal injury contributes to the development of post-stroke epilepsy.MethodsWe performed a retrospective observational study of patients hospitalized between 1/2007 and 12/2018 with an acute stroke in the Stroke Center of the Geneva Universit...
Source: Journal of Neurology - July 7, 2022 Category: Neurology Source Type: research
Comparing characteristics and outcomes of in-hospital stroke and community-onset stroke
ConclusionCompared with community-onset strokes, the patients with in-hospital stroke had insufficient urgent treatment and poorer outcomes, reflecting the need for increased awareness of in-patient stroke, and strategies to streamline in-hospital acute stroke care.
Source: Journal of Neurology - July 2, 2022 Category: Neurology Source Type: research
