Thrombocytopenia and declines in platelet counts: predictors of mortality and outcome after mechanical thrombectomy

ConclusionIn AIS patients treated with MT an initial TP was independently associated with higher mortality rates and a marked DPC with higher mortality rates as well as poorer clinical outcomes.
Source: Journal of Neurology - Category: Neurology Source Type: research

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An article highlighting a lack of female invited speakers at a major scientific medical meeting caused International Stroke Conference organizers to encourage more women to attend and to speak at the event.Medscape Medical News
Source: Medscape Cardiology Headlines - Category: Cardiology Tags: Neurology & Neurosurgery News Source Type: news
We examined the association between baseline PH composite and cancer mortality adjusted for potential confounders using Cox regression. A total of 1191 cancer deaths were observed over the 10-year observation period, with the majority being lung (26.87%) and gastrointestinal (21.49%) cancers. Even after controlling for sociodemographics, health behaviors, baseline comorbidity score, and medications, participants with No PA and High RPP had 71% greater risk of cancer mortality when compared to participants with PA and Low RPP (adjusted HR: 1.71, 95% CI: 1.42–2.06). These associations persisted after examining BMI, smo...
Source: Preventive Medicine - Category: International Medicine & Public Health Source Type: research
In conclusion, implementation of the CMD prevention program resulted in the detection of two- to threefold more patients with CMD. A significant drop in systolic blood pressure and cholesterol levels was found after one year of treatment. Modelling of these results should confirm the effect on long term endpoints.Trial registration: Dutch trial Register number NTR4277.
Source: Preventive Medicine - Category: International Medicine & Public Health Source Type: research
Young and middle-aged adults who vape and smoke are more likely to have had a stroke than those who use only one of these types of nicotine product, or none at all, a study suggests.
Source: Reuters: Health - Category: Consumer Health News Tags: healthNews Source Type: news
Stroke risk factors are also increasing in young women and more needs to be done to identify and treat high-risk patients in early pregnancy, authors of a new study urge.Medscape Medical News
Source: Medscape Neurology and Neurosurgery Headlines - Category: Neurology Tags: Neurology & Neurosurgery News Source Type: news
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Source: Expert Opinion on Therapeutic Targets - Category: Drugs & Pharmacology Authors: Source Type: research
Publication date: Available online 15 January 2020Source: Canadian Journal of CardiologyAuthor(s): Ming-Jer Hsieh, Cheng-Hung Lee, Ming-Lung Tsai, Chang-Fu Kao, Wen-Ching Lan, Yu-Tung Huang, Wen-Yi Tseng, Ming-Shien Wen, Shang-Hung ChangAbstractBackgroundTumor necrosis factor inhibitors (TNFi) improve joints outcomes and reduce cardiovascular (CV) risk in patients with rheumatoid arthritis (RA). However, 20-45% of RA patients are TNFi poor responders and have a significantly higher risk of CV events. In these TNFi non-responders, the use of second-line biological agents to improve synovial outcomes is supported by clinical...
Source: Canadian Journal of Cardiology - Category: Cardiology Source Type: research
Publication date: Available online 15 January 2020Source: American Heart JournalAuthor(s): Matthew E Ehrlich, Brad J Kolls, Mayme Roettig, Lisa Monk, Shreyansh Shah, Ying Xian, James G Jollis, Christopher B Granger, Carmelo GraffagninoAbstractThe AHA Guidelines recommend developing multi-tiered systems for the care of patients with acute stroke.1 An ideal stroke system of care should ensure that all patients receive the most efficient and timely care, regardless of how they first enter or access the medical care system. Coordination among the components of a stroke system is the most challenging but most essential aspect o...
Source: American Heart Journal - Category: Cardiology Source Type: research
In this study, we found that nuclear receptors FXR and LXR (originally characterized as regulatory factors involved in cholesterol/bile acid homeostasis) regulate the expression of Oct3/4, a marker for cell differentiation, in both normal renal-derived cell line HK-2 and renal adenocarcinoma cell line ACHN. Down-regulation of Oct3/4 expression by activating FXR and LXR occurs only in normal renal cell-derived HK-2 cells. We also found that the RNA-binding protein, ELAVL2, oppositely regulates Oct3/4 expressions in HK-2 and ACHN cells. Moreover, we revealed that LXR-alpha and LXR-beta regulate each other's expression. Altho...
Source: Journal of Toxicological Sciences - Category: Toxicology Tags: J Toxicol Sci Source Type: research
Publication date: Available online 16 January 2020Source: NeurocomputingAuthor(s): Ruiqi Wu, Changle Zhou, Fei Chao, Longzhi Yang, Chih-Min Lin, Changjing ShangAbstractAs a combination of robotic motion planning and Chinese calligraphy culture, robotic calligraphy plays a significant role in the inheritance and education of Chinese calligraphy culture. Most existing calligraphy robots focus on enabling the robots to learn writing through human participation, such as human-robot interactions and manually designed evaluation functions. However, because of the subjectivity of art aesthetics, these existing methods require a l...
Source: Neurocomputing - Category: Neuroscience Source Type: research
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