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Total 19 results found since Jan 2013.

A Post-hoc Study of D-Amino Acid Oxidase in Blood as an Indicator of Post-stroke Dementia
In conclusion, our data support that plasma DAO levels were increased in PSD patients and correlated with brain WMH, independent of age, gender, hypertension, and renal function. Plasma DAO levels may therefore aid in PSD diagnosis. Introduction Stroke is a risk factor for both vascular dementia and Alzheimer's disease (1, 2). Functional recovery develops over the course of 26 weeks after a stroke (3), but the survivors are often left with disabilities. In addition to the sequelae of acute neuronal damage, the 1-year post-stroke dementia (PSD) rates after first-ever and recurrent stroke are ~10 and 30...
Source: Frontiers in Neurology - April 25, 2019 Category: Neurology Source Type: research

Health-Related Quality of Life in Stroke Survivors in Relation to the Type of Inpatient Rehabilitation in Serbia: A Prospective Cohort Study.
Conclusions: There was a significant difference in health-related quality of life perceived by stroke survivors who underwent additional hospital rehabilitation in relation to those who underwent only inpatient rehabilitation. PMID: 33266160 [PubMed - in process]
Source: Medicina (Kaunas) - November 30, 2020 Category: Universities & Medical Training Authors: Rancic NK, Mandic MN, Kocic BN, Veljkovic DR, Kocic ID, Otasevic SA Tags: Medicina (Kaunas) Source Type: research

Cost-effectiveness analysis of dronedarone versus amiodarone, propafenone and sotalol in patients with atrial fibrillation: results for Serbia.
CONCLUSIONS: Results of our model indicate that dronedarone is cost effective therapy compared with amiodarone, propafenone and sotalol in patients with atrial fibrillation if the outcome is number of years spent without stroke. PMID: 25428811 [PubMed - as supplied by publisher]
Source: Polish Heart Journal - November 27, 2014 Category: Cardiology Authors: Tesic D, Kostic M, Paunovic D, M Jankovic S Tags: Kardiol Pol Source Type: research

Relationship between cerebrovascular and valvular manifestations in a Serbian cohort of patients with antiphospholipid syndrome.
CONCLUSIONS: In this cross-section analysis of a large cohort of Serbian APS patients, there was a strong relationship between valvular and cerebrovascular manifestations, suggesting a more cautious approach regarding neurological symptoms, especially in PAPS patients with valvular vegetations present. PMID: 29846156 [PubMed - as supplied by publisher]
Source: Clinical and Experimental Rheumatology - June 4, 2018 Category: Rheumatology Tags: Clin Exp Rheumatol Source Type: research

Harnessing the Four Elements for Mental Health
DiscussionAs detailed above, the “elements” in both a classical and a contemporary sense have effects on our mental health and are potentially modifiable aspects that can be harnessed as therapeutic interventions. The most robust interventional evidence currently available shows tentative support for several use of the elements via horticultural and nature-exposure therapy, green exercise/physical activity, sauna and heat therapy, balneotherapy, and breathing exercises. It should be noted that, in many cases, these interventions were not studied in definitive diagnosed psychiatric disorders and thus it is pre...
Source: Frontiers in Psychiatry - April 23, 2019 Category: Psychiatry Source Type: research

The association of clopidogrel and 2-oxo-clopidogrel plasma levels and the 40  months clinical outcome after primary PCI
Conclusion Clopidogrel dose-adjusted plasma concentration in STEMI patients, as well as multivessel coronary artery disease, showed significance in predicting an unfavorable composite clinical outcome after 40-month follow-up.
Source: International Journal of Clinical Pharmacy - October 26, 2018 Category: Drugs & Pharmacology Source Type: research

Genotype phenotype correlation in a pediatric population with antithrombin deficiency
Conclusion: Type II HBS (AT Budapest 3) in the homozygous form is a strong risk factor for arterial and venous thrombosis in pediatric patients.What is Known:•Inherited AT deficiency is a rare autosomal dominant disorder, caused by mutations in the SERPINC1gene.•The genotype phenotype correlation in AT deficiency patients remains unclear, especially in pediatric patients.What is New:•The genetic results for our paediatric population predominantly showed the presence of a single specific mutation in exon 2, that causes type II HBS deficiency (AT Budapest 3).•In this group thrombosis mostly occurred as unprovoked, in...
Source: European Journal of Pediatrics - July 28, 2019 Category: Pediatrics Source Type: research

Cost-effectiveness of a photopethysmographic procedure for screening for atrial fibrillation in 6 European countries
ConclusionThe model results showed a strong dependence of the results on the country-specific costs for stroke treatment. The use of the investigated screening method is close to cost-neutral or cost-reducing in the Western European countries and Greece. In countries with low price levels, higher cost increases due to AF screening are to be expected. Lower costs of anticoagulation, which are expected due to the upcoming patent expiry of direct anticoagulants, have a positive effect on the cost result.
Source: Health Economics Review - February 26, 2022 Category: International Medicine & Public Health Source Type: research

Association of MMP1 and MMP3 haplotypes with myocardial infarction and echocardiographic parameters of the left ventricle
ConclusionMMP1 andMMP3 haplotypes are strongly associated with MI. Further studies are needed to validate this result and to examine their association with echocardiographic parameters of LV structure and function after MI.
Source: Molecular Genetics & Genomic Medicine - August 1, 2022 Category: Genetics & Stem Cells Authors: Tamara Djuric, Jovana Kuveljic, Ana Djordjevic, Milica Dekleva, Goran Stankovic, Aleksandra Stankovic, Maja Zivkovic Tags: ORIGINAL ARTICLE Source Type: research

IS 22. Coupling of motor imagination and nervous system stimulation to induce cortical plasticity
We recently developed a novel technique for inducing plasticity in the human motor cortex by combining the physiologically generated signal when a person imagines a simple dorsiflexion task with the peripheral stimulation of the nerve that innervates the muscle involved in the task (). The subject activates the relevant brain areas via imagination and is provided with the expected afferent feedback via the single peripheral electrical stimulation to the target nerve. This protocol induced significant plasticity only when the afferent volley was timed to arrive during the peak negativity (PN) of the movement-related cortica...
Source: Clinical Neurophysiology - September 1, 2013 Category: Neuroscience Authors: N. Mrachacz-Kersting, N. Jiang, K. Dremstrup, D. Farina Tags: Society Proceedings Source Type: research

The prevalence of COPD co-morbidities in Serbia: results of a national survey.
Conclusion:Our analysis showed that the most prevalent co-morbidities in COPD were hypertension, dyslipidaemia, chronic renal disease and anxiety/depression. The finding suggests that health professionals should actively assess co-morbidities in patients with COPD. PMID: 24921714 [PubMed - as supplied by publisher]
Source: Primary Care - June 13, 2014 Category: Primary Care Authors: Nagorni-Obradovic LM, Vukovic DS Tags: NPJ Prim Care Respir Med Source Type: research

Age at death of major cardiovascular diseases in 13 cohorts. The seven countries study of cardiovascular diseases 45-year follow-up.
CONCLUSIONS: AD is a useful indicator of previous health and aging populations. STR and HDUE are diseases appearing later in life, thus being associated with a higher AD compared with CHD mortality. PMID: 29570017 [PubMed - as supplied by publisher]
Source: Acta Cardiologica - March 28, 2018 Category: Cardiology Tags: Acta Cardiol Source Type: research

Orexin-A Prevents Lipopolysaccharide-Induced Neuroinflammation at the Level of the Intestinal Barrier
We examined a possible protective effect of OX-A against LPS-induced ROS formation and microglia activation. To mimic in vitro the connection between gut and brain and to study the putative effect on the cortical microglia, we used a co-culture of Caco-2 cells and primary cortical microglia with Caco-2 cells placed at the apical side of a transwell and primary cortical microglia at the basolateral side. All treatments used to study the apical vs. basal connection were applied to the apical compartment. We used DHR (10 μM, 20 min), a cell-permeable fluorogenic probe useful for the detection of ROS formation, to dete...
Source: Frontiers in Endocrinology - April 9, 2019 Category: Endocrinology Source Type: research