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Infectious Disease: Meningitis
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Total 171 results found since Jan 2013.

Stroke in patients with tuberculous meningitis in a low TB endemic country: an increasing medical emergency?
This study evaluated the frequency, clinical characteristics, risk factors and outcomes of patients with TBM complicated by stroke admitted to the Infectious Disease Clinic, University of Perugia Hospital, Italy from 1971 to 2010. Over four decades, 419 patients were admitted with tuberculosis, of these 30 (7.1%) were diagnosed with TBM: 20 definite, one probable and nine possible. Twenty-six were evaluable for stroke and six (23%) had stroke. The latter six had advanced stages of meningitis, two tested HIV positive, three HIV negative and in one HIV was not performed. Of seven patients without stroke tested for HIV, only ...
Source: New Microbiologica - December 1, 2014 Category: Microbiology Tags: New Microbiol Source Type: research

The value of C-reactive protein in emergency medicine
Publication date: 2014 Source:Journal of Acute Disease, Volume 3, Issue 1 Author(s): Yu-Jang Su C-reactive protein (CRP) is a commonly used tool in emergency department (ED), especially in febrile and infectious patients. It was identified in 1930 and was subsequently classified into an “acute phase protein”, an early indicator of infectious or inflammatory situations in the ED, CRP must be a diagnostic reference and no single value can be indicated to rule in or rule out a specific diagnosis or disease. CRP is a comprehensively assisted tool for evaluation and diagnosis of tissue damage (rheumatologic diseases, stro...
Source: Journal of Acute Disease - November 2, 2014 Category: Emergency Medicine Source Type: research

Cerebral infarction and tuberculoma in central nervous system tuberculosis: frequency and prognostic implications
Conclusions Tuberculomas were present in 50% of patients, while infarcts were present in 25%. Old age, TBM grading, presence of infarction and hydrocephalus were all predictors of poor outcome.
Source: Journal of Neurology, Neurosurgery and Psychiatry - October 17, 2014 Category: Neurosurgery Authors: Wasay, M., Farooq, S., Khowaja, Z. A., Bawa, Z. A., Ali, S. M., Awan, S., Beg, M. A., Mehndiratta, M. M. Tags: Meningitis, Hydrocephalus, Infection (neurology), Stroke Neuroinfection Source Type: research

Timing and number of minor infections as risk factors for childhood arterial ischemic stroke
Conclusions: Minor infections appear to have a strong but short-lived effect on pediatric stroke risk, while cumulative burden of infection had no effect. Proposed mechanisms for the link between minor infection and stroke in adults include an inflammatory-mediated prothrombotic state and chronic endothelial injury. The transient effect of infection in children may suggest a greater role for a prothrombotic mechanism.
Source: Neurology - September 1, 2014 Category: Neurology Authors: Hills, N. K., Sidney, S., Fullerton, H. J. Tags: Childhood stroke, All Infections, Pediatric stroke; see Cerebrovascular Disease/ Childhood stroke, Case control studies ARTICLE Source Type: research

Stroke in paediatric patients with sickle-cell anaemia.
CONCLUSIONS. Drepanocytosis is a disease that is emerging in our setting as a result of immigration. It should be suspected in cases of paediatric strokes associated to anaemia, above all in black children under the age of five who were not submitted to neonatal screening. PMID: 25059265 [PubMed - in process]
Source: Revista de Neurologia - July 29, 2014 Category: Neurology Authors: Diaz-Diaz J, Camacho-Salas A, Nunez-Enamorado N, Carro-Rodriguez MA, Sanchez-Galan V, Martinez de Aragon A, Simon-De Las Heras R Tags: Rev Neurol Source Type: research

Central Nervous System Complications of Varicella-Zoster Virus
Conclusion: Neurologic complications of VZV infection continue to occur despite the availability of an effective vaccine. Neurologic symptom onset can predate the appearance of the VZV exanthem and in rare cases may occur in the absence of an exanthem.
Source: The Journal of Pediatrics - July 24, 2014 Category: Pediatrics Authors: Michelle Science, Daune MacGregor, Susan E. Richardson, Sanjay Mahant, Dat Tran, Ari Bitnun Tags: Original Articles Source Type: research

Antithrombotic Therapy for Secondary Stroke Prevention in Bacterial Meningitis in Children
Conclusion: In this small sample, heparin and ASA appeared to be safe in childhood bacterial meningitis complicated by stroke and may be effective in improving outcome. Heparin may be more effective than aspirin in preventing recurrent infarction.
Source: The Journal of Pediatrics - July 24, 2014 Category: Pediatrics Authors: Cyrus Boelman, Manohar Shroff, Ivanna Yau, Bruce Bjornson, Susan Richrdson, Gabrielle deVeber, Daune MacGregor, Mahendranathn Moharir, Rand Askalan Tags: Original Articles Source Type: research

Resolution of a fungal mycotic aneurysm after a contaminated steroid injection: a case report
Conclusions: This is the rare case report of successful medical management of a cerebral mycotic aneurysm with stroke symptoms related to a presumed phaeohyphomycosis in an immunocompetent individual. Further studies are needed to determine the utility of cerebrospinal fluid (1, 3) beta-D-glucan in diagnosing and monitoring patients with meningitis thought to be related to fungal infection.
Source: BMC Research Notes - May 31, 2014 Category: Research Authors: George NelsonOlga FermoKiran ThakurElizabeth FeltonJee BangLucy WilsonSusan RheeRafael LlinasKristine JohnsonDavid Sullivan Source Type: research

Meningeal Disease Masquerading as Transient Ischemic Attack
Conclusions: Our study confirmed that serious meningeal disease could present as TIA, but this disease was relatively uncommon among patients treated in a TIA clinic. The findings highlight the diagnostic value of MRI in patients with suspected TIA.
Source: Journal of Stroke and Cerebrovascular Diseases - April 25, 2014 Category: Neurology Authors: Line Cuinat, Nathalie Nasr, Jeanine Manuela Kamsu, Frédéric Tanchoux, Fabrice Bonneville, Vincent Larrue Tags: Case Reports Source Type: research

NeurologicManifestations of Neglected Tropical Diseases (P4.295)
CONCLUSIONS: Neurological manifestations of NTDs cause significant morbidity and mortality, although data are limited. The evidence for treatments of neurologic complications is limited for most NTDs. Increased awareness of neurologic manifestations of NTDs can promote early identification and treatment, thereby contributing to ongoing elimination and eradication campaigns.Study Supported by: NADisclosure: Dr. Raibagkar has nothing to disclose. Dr. Berkowitz has received royalty payments from Medmaster and Oxford University Press. Dr. Pritt has nothing to disclose. Dr. Headley-Whyte has nothing to disclose. Dr. Mateen has nothing to disclose.
Source: Neurology - April 9, 2014 Category: Neurology Authors: Raibagkar, P., Berkowitz, A., Pritt, B., Headley-Whyte, E. T., Mateen, F. Tags: Global Health and Infection Source Type: research

The Risk of Large-Artery Atherosclerotic Stroke is Proportionally Greater than Cardioembolic Stroke in HIV-Infected Individuals Compared to HIV-Uninfected Controls (P4.304)
CONCLUSIONS: HIV-infected individuals with well-controlled infection may be at proportionally greater risk for large artery atherosclerotic versus cardioembolic stroke compared to uninfected individuals. Additional studies are warranted to confirm this association and explore potential mechanisms underlying this difference, including the role of chronic inflammation.Disclosure: Dr. Price has received personal compensation for activities with Abbott Laboratories as a speaker. Dr. Hsue has nothing to disclose. Dr. Kim has received research support from SanBio, Inc.
Source: Neurology - April 9, 2014 Category: Neurology Authors: Chow, F., Price, R., Hsue, P., Kim, A. Tags: NeuroAIDS Source Type: research

The Risk of Large-Artery Atherosclerotic Stroke is Proportionally Greater than Cardioembolic Stroke in HIV-Infected Individuals Compared to HIV-Uninfected Controls (I10-1.003)
CONCLUSIONS: HIV-infected individuals with well-controlled infection may be at proportionally greater risk for large artery atherosclerotic versus cardioembolic stroke compared to uninfected individuals. Additional studies are warranted to confirm this association and explore potential mechanisms underlying this difference, including the role of chronic inflammation.Disclosure: Dr. Price has received personal compensation for activities with Abbott Laboratories as a speaker. Dr. Hsue has nothing to disclose. Dr. Kim has received research support from SanBio, Inc.
Source: Neurology - April 9, 2014 Category: Neurology Authors: Chow, F., Price, R., Hsue, P., Kim, A. Tags: The Global Burden of Neurological Diseases Poster Presentations Source Type: research

Predictive Factors of Central Nervous Infection: Prospective Evaluation of 124 Cases with Suspicion of Meningitis. (P2.303)
Discussion and conclusions: The presence of meningeal signs, hypoglucorraquia and low PH in CSF are the most suggestive findings of meningitis, when compared to fever, mental status changes or other variables. Initial CSF image should include the application of constrast when possible.Disclosure: Dr. Trevino has nothing to disclose. Dr. Gonzalez Duarte has nothing to disclose. Dr. Avila-Funes has nothing to disclose.
Source: Neurology - April 9, 2014 Category: Neurology Authors: Trevino, I., Gonzalez Duarte, M. A., Avila-Funes, A. Tags: CNS Infectious Disease: Miscellaneous Source Type: research

What Causes Ataxia?
Discussion Coordination and balance problems are caused by various problems affecting the central and peripheral nervous system. Normal development of a child or weakness of a child are commonly mistaken for true ataxia. Ataxia specifically refers to “…impairment of the coordination of movement without loss of muscle strength.” If it is purely due to abnormalities of the cerebellum then there should be no changes in mental status, sensation or weakness. Sometimes it is difficult to determine if there are abnormalities in other areas. For example, Guillian-Barre often presents with difficulty or clumsy wal...
Source: PediatricEducation.org - March 31, 2014 Category: Pediatrics Authors: pediatriceducationmin Tags: Uncategorized Source Type: news

Safety of diphtheria, tetanus, acellular pertussis and inactivated poliovirus (DTaP-IPV) vaccine.
CONCLUSIONS: In this safety surveillance study of more than 200,000 DTaP-IPV vaccine recipients, there was no evidence of increased risk for any of the pre-specified adverse events monitored. Continued surveillance of DTaP-IPV vaccine safety may be warranted to monitor for rare adverse events, such as Guillain-Barré syndrome. PMID: 24699471 [PubMed - as supplied by publisher]
Source: Vaccine - March 31, 2014 Category: Allergy & Immunology Authors: Daley MF, Yih WK, Glanz JM, Hambidge SJ, Narwaney KJ, Yin R, Li L, Nelson JC, Nordin JD, Klein NP, Jacobsen SJ, Weintraub E Tags: Vaccine Source Type: research