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Total 411 results found since Jan 2013.

Patient-centered Outcomes with Concomitant Use of Proton Pump Inhibitors and Other Drugs.
Abstract PURPOSE: We performed a systematic review of patient-centered outcomes after the concomitant use of proton pump inhibitors (PPIs) and other drugs. METHODS: We searched 4 databases in July 2016 to find studies that reported mortality and morbidity after the concomitant use of PPIs and other drugs. We conducted direct meta-analyses using a random-effects model and graded the quality of evidence according to the Grading of Recommendations Assessment, Development and Evaluation working group approach. FINDINGS: We included data from 17 systematic reviews and meta-analyses, 16 randomized controlled t...
Source: Clinical Therapeutics - February 8, 2017 Category: Drugs & Pharmacology Authors: Shamliyan TA, Middleton M, Borst C Tags: Clin Ther Source Type: research

The Associations of Atrial Fibrillation With the Risks of Incident Invasive Breast and Colorectal Cancer
<span class="paragraphSection"><div class="boxTitle">Abstract</div>Atrial fibrillation (AF) is a common arrhythmia that poses a significant risk of stroke. Cross-sectional and case-control studies have shown evidence of associations between AF and breast or colorectal cancer, but there have been no longitudinal studies in which this has been assessed. We prospectively examined a cohort of 93,676 postmenopausal women enrolled in the Women's Health Initiative from 1994 to 1998 to determine whether there are relationships between baseline AF and the development of invasive breast or colorectal cancer. The pr...
Source: American Journal of Epidemiology - February 7, 2017 Category: Epidemiology Source Type: research

The evolving role of oral hormonal therapies and review of conjugated estrogens/bazedoxifene for the management of menopausal symptoms.
Authors: Parish SJ, Gillespie JA Abstract This review describes the evolving role of oral hormone therapy (HT) for treating menopausal symptoms and preventing osteoporosis, focusing on conjugated estrogens/bazedoxifene (CE/BZA). Estrogens alleviate hot flushes and prevent bone loss associated with menopause. In nonhysterectomized women, a progestin should be added to estrogens to reduce the risk of endometrial cancer. Use of HT declined since the Women's Health Initiative (WHI) studies showed that HT does not prevent coronary heart disease (CHD) and that conjugated estrogens/medroxyprogesterone acetate increased th...
Source: Postgraduate Medicine - February 1, 2017 Category: Internal Medicine Tags: Postgrad Med Source Type: research

Improvement in quality of hospital care during accreditation: A nationwide stepped-wedge study
Conclusion</div>These findings support the hypothesis that hospital accreditation leads to improvements in patient care.</span>
Source: International Journal for Quality in Health Care - January 31, 2017 Category: Global & Universal Source Type: research

Estrogen alone and health outcomes in black women by African ancestry: a secondary analyses of a randomized controlled trial
Conclusions: In black postmenopausal women with prior hysterectomy, estrogen alone significantly reduced breast cancer incidence with no adverse influence on CHD, venous thromboembolism, or all-cause mortality. Favorable estrogen-alone global index effects in younger black women warrant further study.
Source: Menopause - January 28, 2017 Category: OBGYN Tags: Original Articles Source Type: research

Mortality of Shift Workers
This study strengthens the evidence of a connection between shift work and all-cause mortality. It also provides support for an association between shift work and mortality of cardiovascular disease. The mechanisms responsible for the association between shift work and disease are probably co mplex and influenced by genetics, lifestyle, sleep, social stress, and disturbed circadian rhythms (7). Further epidemiological studies and experimental studies are needed to explain the causal pathways. One issue would be to find a better variable measuring the circadian phase. Shift work is not a valid proxy since previous studies...
Source: Scandinavian Journal of Work, Environment and Health - January 25, 2017 Category: Occupational Health Tags: Editorial Source Type: research

Long-term hormone therapy for perimenopausal and postmenopausal women.
CONCLUSIONS: Women with intolerable menopausal symptoms may wish to weigh the benefits of symptom relief against the small absolute risk of harm arising from short-term use of low-dose HT, provided they do not have specific contraindications. HT may be unsuitable for some women, including those at increased risk of cardiovascular disease, increased risk of thromboembolic disease (such as those with obesity or a history of venous thrombosis) or increased risk of some types of cancer (such as breast cancer, in women with a uterus). The risk of endometrial cancer among women with a uterus taking oestrogen-only HT is well docu...
Source: Cochrane Database of Systematic Reviews - January 16, 2017 Category: Journals (General) Authors: Marjoribanks J, Farquhar C, Roberts H, Lethaby A, Lee J Tags: Cochrane Database Syst Rev Source Type: research

Behind the Headlines 2016 Quiz of the Year
In 2014, Behind the Headlines has covered more than 500 health stories that made it into the mainstream media. If you've been paying attention you should find this quiz easy and fun. Why not test your knowledge of 2014's health news with our month-by-month quiz? Answers are at the foot of the page (no peeking!).   In January 2016's health news... In a controversial study, monkeys were genetically engineered to develop what disorder? 1) Sex addiction 2) Bi-polar disorder 3) Autism In a similarly controversial study, what psychological condition was dismissed as a "myth" 1) Seasonal affective disorder...
Source: NHS News Feed - December 5, 2016 Category: Consumer Health News Tags: Special reports Source Type: news

Work after age 65: A prospective study of Australian men and women
ConclusionThis study quantifies the importance of education and health factors in determining continued participation of Australian men and women in paid work in later life. These factors need to be considered for policies aiming to increase workforce participation beyond 65 years of age.
Source: Australasian Journal on Ageing - November 30, 2016 Category: Geriatrics Authors: Tazeen Majeed, Peta M Forder, Meredith Tavener, Kha Vo, Julie Byles Tags: Research Article Source Type: research

Milk and dairy products: good or bad for human health? An assessment of the totality of scientific evidence.
CONCLUSION: The totality of available scientific evidence supports that intake of milk and dairy products contribute to meet nutrient recommendations, and may protect against the most prevalent chronic diseases, whereas very few adverse effects have been reported. PMID: 27882862 [PubMed - in process]
Source: Food and Nutrition Research - November 26, 2016 Category: Nutrition Authors: Thorning TK, Raben A, Tholstrup T, Soedamah-Muthu SS, Givens I, Astrup A Tags: Food Nutr Res Source Type: research

Common diseases as determinants of menopausal age
STUDY QUESTION Can the diagnosis of common diseases before menopause influence age at natural menopause (ANM) onset? SUMMARY ANSWER Polycystic ovary syndrome (PCOS) and depression were observed to delay menopause. WHAT IS KNOWN ALREADY It has been observed that women who undergo early menopause experience a higher burden of health problems related to metabolic syndromes, heart disease and depression, but whether ANM can be influenced by common adult diseases has not been studied extensively. STUDY DESIGN, SIZE, DURATION All women attending mammography screening or clinical mammography at four hospitals in Sweden were in...
Source: Human Reproduction - November 16, 2016 Category: Reproduction Medicine Authors: Li, J., Eriksson, M., Czene, K., Hall, P., Rodriguez-Wallberg, K. A. Tags: Reproductive Epidemiology Source Type: research

Mediterranean diet and life expectancy; beyond olive oil, fruits, and vegetables
Purpose of review: The recent relevant evidence of the effects of the Mediterranean diet (MedDiet) and lifestyle on health (2015 and first months of 2016). Recent findings: Large observational prospective epidemiological studies with adequate control of confounding and two large randomized trials support the benefits of the Mediterranean dietary pattern to increase life expectancy, reduce the risk of major chronic disease, and improve quality of life and well-being. Recently, 19 new studies from large prospective studies showed – with nearly perfect consistency – strong benefits of the MedDiet to reduce the risk of my...
Source: Current Opinion in Clinical Nutrition and Metabolic Care - October 7, 2016 Category: Nutrition Tags: NUTRITION AND PHYSIOLOGICAL FUNCTION: Edited by Annemie M.W.J. Schols and Labros S. Sidossis Source Type: research

How Your Diet May Affect Your Risk of Breast Cancer
By Stacy SimonHave you ever said “no thanks” to a tempting dessert or eaten only salad for lunch because you were trying to cut back? If so, you’re among many women who try every day to protect their health by eating right. The American Cancer Society recommends eating mostly vegetables, fruits, and whole grains, and less red meat (beef, pork, and lamb), less processed meat (bacon, sausage, luncheon meats, and hot dogs), and fewer sweets. A healthy diet can help reduce the risk of heart disease, diabetes, stroke, and certain cancer types.A healthy diet can also help you get to and stay at a healthy weight...
Source: American Cancer Society :: News and Features - September 30, 2016 Category: Cancer & Oncology Tags: Breast Cancer Diet/Exercise/Weight Prevention/Early Detection Source Type: news

Say Yes to Yoga
By Stacy SimonThe ancient Indian practice of yoga combines meditation, breathing, and precise postures and poses to make a connection with thoughts, body, and spirit. People who practice yoga claim it leads to a state of physical health, relaxation, happiness, peace, and tranquility.Some evidence shows that yoga can lower stress, increase strength, and lessen lower back pain, while providing exercise. And according to a report from the National Institutes of Health, there is also some evidence to suggest yoga may be helpful when used alongside conventional medical treatment to help relieve some of the symptoms linked to ca...
Source: American Cancer Society :: News and Features - September 1, 2016 Category: Cancer & Oncology Tags: Complementary and Alternative Methods Source Type: news

A Radiologist ’s Primer on Bundles and Care Episodes
Publication date: September 2016 Source:Journal of the American College of Radiology, Volume 13, Issue 9 Author(s): David Seidenwurm, Frank James Lexa Bundled or episode payments are among the most heavily emphasized approaches to aligning incentives and promoting care coordination, efficiency, and accountability in health care redesign. Bundled or episode payments price a market basket of services for an entire episode of care with both a clearly defined trigger and termination. Because the radiologist is “ancillary” in many bundles, the specialty is often unaware of the phenomenon. This is likely to change rapidly. ...
Source: Journal of the American College of Radiology - August 31, 2016 Category: Radiology Source Type: research