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Total 411 results found since Jan 2013.

Predicted cardiac and second cancer risks for patients undergoing VMAT for mediastinal Hodgkin lymphoma
CONCLUSION: For patients with mediastinal lymphoma excess mortality risks from CVD and second cancers remain clinically significant despite contemporary chemotherapy and photon-RT. Efforts to reduce the toxicity of combined modality treatment, for example, using DIBH, reduced margins and advanced RT, e.g. proton beam therapy, should be continued to further reduce potentially fatal treatment effects.PMID:36585562 | DOI:10.1007/s12094-022-03034-z
Source: Clinical Lung Cancer - December 30, 2022 Category: Cancer & Oncology Authors: Orla A Houlihan Georgios Ntentas David J Cutter Patricia Daly Charles Gillham Orla McArdle Frances K Duane Source Type: research

Osteoporotic fracture admissions compared to other major medical admissions in Irish public hospitals
ConclusionOsteoporotic fractures represent a large and rapidly increasing illness burden amongst older Irish adults, with substantial care requirements and the resulting onus on our healthcare system. Urgent action is needed to address this public health issue and the services for those at risk of fracture.
Source: Archives of Osteoporosis - December 17, 2022 Category: Orthopaedics Source Type: research

Bleeding and thrombotic events in atrial fibrillation patients with cancer: a systematic review and meta-analysis
AbstractAtrial fibrillation (AF) and cancer are frequently coexisting in elderly patients. Pooled metanalytic data on the impact of cancer on clinical outcomes in AF patients are lacking.  We performed a systematic review and meta-regression analysis of clinical studies retrieved from Medline (PubMed) and Cochrane (CENTRAL) databases according to PRISMA guidelines. Bleeding endpoints included any, major, gastrointestinal (GI) bleeding and intracranial haemorrhage (ICH). Cardiovascul ar (CV) endpoints included myocardial infarction (MI), ischemic stroke/systemic embolism (IS/SE), CV and all-cause death. PROSPERO registrati...
Source: Internal and Emergency Medicine - December 8, 2022 Category: Emergency Medicine Source Type: research

Risk of venous thromboembolism among women receiving ospemifene: a comparative observational study
Conclusion: This real-world safety analysis found no increase in risk of VTE or other adverse events with use of ospemifene in postmenopausal women.PMID:36420373 | PMC:PMC9677319 | DOI:10.1177/20420986221135931
Source: Cancer Control - November 24, 2022 Category: Cancer & Oncology Authors: Beth L Nordstrom Bin Cai Fabio De Gregorio Lu Ban Kathy H Fraeman Yuki Yoshida Trevor Gibbs Source Type: research

Association Between Aromatase Inhibitors and Myocardial Infarction Morbidity in Women With Breast Cancer: A Meta-Analysis of Observational Studies
CONCLUSION: Based on real-world data, AIs may be a safe treatment route for patients with estrogen receptor-positive breast cancer and those with a history of CVD. AIs caused a major decrease in MI in patients without CVD history. However, more in-depth investigations are needed to explore the association between AI use and the incidence of MI in the treatment of estrogen receptor-positive breast cancer.PMID:36346929 | DOI:10.1177/10732748221132512
Source: Cancer Control - November 8, 2022 Category: Cancer & Oncology Authors: Jing-Chao Sun Ze-Fan Sun Chao-Jie He Chang-Lin Zhai Gang Qian Source Type: research

Exercise for the Prevention of Anthracycline-induced Functional Disability and Cardiac Dysfunction: The BReast Cancer Randomized EXercise InTervention (BREXIT) Study
Conclusions: In women with early-stage BC undergoing AC, 12-months of ExT did not attenuate functional disability but provided large and clinically meaningful benefits on VO2peak and cardiac reserve. Clinical Trial Registration: URL: https://www.anzctr.org.au/ Unique Identifier: ACTRN12617001408370.PMID:36342348 | DOI:10.1161/CIRCULATIONAHA.122.062814
Source: Circulation - November 7, 2022 Category: Cardiology Authors: Stephen J Foulkes Erin J Howden Mark J Haykowsky Yoland Antill Agus Salim Sophie S Nightingale Sherene Loi Piet Claus Kristel Janssens Amy M Mitchell Leah Wright Ben T Costello Anniina Lindqvist Lauren Burnham Imogen Wallace Robin M Daly Steve F Fraser An Source Type: research

How AI Is Changing Medical Imaging to Improve Patient Care
That doctors can peer into the human body without making a single incision once seemed like a miraculous concept. But medical imaging in radiology has come a long way, and the latest artificial intelligence (AI)-driven techniques are going much further: exploiting the massive computing abilities of AI and machine learning to mine body scans for differences that even the human eye can miss. Imaging in medicine now involves sophisticated ways of analyzing every data point to distinguish disease from health and signal from noise. If the first few decades of radiology were about refining the resolution of the pictures taken of...
Source: TIME: Health - November 4, 2022 Category: Consumer Health News Authors: Alice Park and Video by Andrew D. Johnson Tags: Uncategorized Frontiers of Medicine 2022 healthscienceclimate Innovation sponsorshipblock Source Type: news

Chronic Oxidative Stress as a Marker of Long-term Radiation-Induced Cardiovascular Outcomes in Breast Cancer
We examined associations of biomarkers of oxidative stress (myeloperoxidase, growth differentiation factor-15, 8-hydroxy-2'-deoxyguanosine [8-OH-dG], placental growth factor), cardiac injury (troponin I, cystatin-C), inflammation (interleukin-6, C-reactive protein), and myocardial fibrosis (transforming growth factor-ß) with long-term RICVD in breast cancer (BC) survivors. We conducted a nested case-control study within the Women's Health Initiative of postmenopausal women with incident BC stages I-III, who received radiation and had pre- and post-BC diagnosis serum samples. Cases (n = 55) were defined as developing incid...
Source: Cancer Control - September 30, 2022 Category: Cancer & Oncology Authors: Alexi Vasbinder Richard K Cheng Susan R Heckbert Hilaire Thompson Oleg Zaslavksy Rowan T Chlebowski Aladdin H Shadyab Lisa Johnson Jean Wactawski-Wende Gretchen Wells Rachel Yung Lisa Warsinger Martin Electra D Paskett Kerryn Reding Source Type: research