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Condition: Dementia
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Total 430 results found since Jan 2013.

Association between vitamin D deficiency and heart failure risk in the elderly
ConclusionsThere was a high prevalence of vitamin D deficiency in the elderly, and the evidence shows a strong association between vitamin D deficiency and increased risk of heart failure in this population.
Source: ESC Heart Failure - August 1, 2017 Category: Cardiology Authors: Catarina Magalh ães Porto, Vanessa De Lima Silva, João Soares Brito Luz, Brivaldo Markman Filho, Vera Magalhães Silveira Tags: Original Research Article Source Type: research

Snoring link to Alzheimer ’s disease unproven
Conclusion This relatively large cross-sectional analysis has found a link between certain measures of breathing problems during sleep and poorer cognitive function in middle-aged to older adults. The strengths of this study include its size and use of a prospective sleep study to assess whether people had sleep apnoea or other problems with breathing during sleep. The use of standard cognitive tests is also a strength. However, the study does have its limitations: The study did have mixed findings – while certain measures of problems with breathing during sleep (e.g. oxygen levels) were associated with cognitive outco...
Source: NHS News Feed - July 24, 2017 Category: Consumer Health News Tags: Neurology Lifestyle/exercise Source Type: news

Structural MRI markers of brain aging early after ischemic stroke
Conclusions: Brain structure is likely to be compromised before ischemic stroke by vascular risk factors. Smaller hippocampal and total brain volumes and increased WMH load represent proxies for underlying vascular brain injury.
Source: Neurology - July 10, 2017 Category: Neurology Authors: Werden, E., Cumming, T., Li, Q., Bird, L., Veldsman, M., Pardoe, H. R., Jackson, G., Donnan, G. A., Brodtmann, A. Tags: MRI, All Cerebrovascular disease/Stroke, Clinical trials Observational study (Cohort, Case control), Alzheimer's disease, Vascular dementia ARTICLE Source Type: research

The 2017 hormone therapy position statement of The North American Menopause Society
Abstract: The 2017 Hormone Therapy Position Statement of The North American Menopause Society (NAMS) updates the 2012 Hormone Therapy Position Statement of The North American Menopause Society and identifies future research needs. An Advisory Panel of clinicians and researchers expert in the field of women's health and menopause was recruited by NAMS to review the 2012 Position Statement, evaluate new literature, assess the evidence, and reach consensus on recommendations, using the level of evidence to identify the strength of recommendations and the quality of the evidence. The Panel's recommendations were reviewed and a...
Source: Menopause - June 27, 2017 Category: OBGYN Tags: Position Statement Source Type: research

Integrating Health Promotion Into Physical Therapy Practice to Improve Brain Health and Prevent Alzheimer Disease.
This article discusses prevention, prediction, plasticity, and participation in the context of preserving brain health and preventing Alzheimer disease and related dementias in aging adults. RECOMMENDATIONS FOR CLINICAL PRACTICE: Rehabilitation professionals have opportunities to slow disease progression through research, practice, and education initiatives. From a clinical perspective, interventions that target brain health through lifestyle changes and exercise interventions show promise for preventing stroke and associated neurovascular diseases in addition to dementia. Physical therapists are well positioned to in...
Source: Physical Therapy - June 20, 2017 Category: Physiotherapy Authors: McGough E, Kirk-Sanchez N, Liu-Ambrose T Tags: J Neurol Phys Ther Source Type: research

Education, Socioeconomic Status, and Intelligence in Childhood and Stroke Risk in Later Life: A Meta-analysis
Conclusions: Education, childhood SES, and intelligence have modest but important associations with lifetime stroke, and hence dementia, risks. Future studies distinguishing between the individual and combined effects of education, childhood SES and intelligence are needed to determine the independent contribution of each factor to stroke risk. See video abstract at, http://links.lww.com/EDE/B210 .
Source: Epidemiology - June 2, 2017 Category: Epidemiology Tags: Social Epidemiology Source Type: research

Brain volume loss precedes cognitive decline in the first year after ischaemic stroke
Conclusions Brain volume loss precedes cognitive decline in the first year after ischaemic stroke. Tracking brain volume after stroke is important because brain volume is predictive of cognitive decline and atrophy is a hallmark of dementia.
Source: Journal of Neurology, Neurosurgery and Psychiatry - May 8, 2017 Category: Neurosurgery Authors: Werden, E., Cumming, T., Bird, L., Khlif, M., Brodtmann, A. Tags: Abstracts Source Type: research

Predictive indices for functional improvement and deterioration, institutionalization, and death among elderly Medicare beneficiaries
Conclusion Predictive indices, or point and scoring systems used to predict outcomes, can identify elderly Medicare beneficiaries at risk of functional deterioration, institutionalization, and death and can aid policy makers, clinicians, and family members in improving care for older adults and supporting successful aging in the community.
Source: PMandR - April 27, 2017 Category: Rehabilitation Source Type: research

Sugar- and Artificially Sweetened Beverages and the Risks of Incident Stroke and Dementia Clinical Sciences
Conclusions—Artificially sweetened soft drink consumption was associated with a higher risk of stroke and dementia.
Source: Stroke - April 24, 2017 Category: Neurology Authors: Matthew P. Pase, Jayandra J. Himali, Alexa S. Beiser, Hugo J. Aparicio, Claudia L. Satizabal, Ramachandran S. Vasan, Sudha Seshadri, Paul F. Jacques Tags: Diet and Nutrition, Epidemiology, Primary Prevention, Risk Factors, Ischemic Stroke Original Contributions Source Type: research

Reported link between diet drinks and dementia and stroke is weak
Conclusion The researchers used data from a large ongoing cohort study to look for links between consumption of sugary and artificially sweetened drinks and risk of stroke or dementia. This cohort study benefits from the large overall sample size, long period of data collection, careful and valid diagnostic assessments, and adjustments for a number of confounders. However, care must be taken when interpreting these results – particularly if latching on to the maximal tripled risk figures reported in the media. There are several points to consider: Small numbers The new number of strokes and dementia in this study was sma...
Source: NHS News Feed - April 21, 2017 Category: Consumer Health News Tags: Food/diet Heart/lungs Neurology Source Type: news

HELIAD study: Dementia prevalence in Greece (P3.095)
Conclusions:The prevalence of dementia and its subtypes in Greece is similar or at the lower range of that reported in many other European countries and globally. In our sample, increased age and decreased level of education status, but not gender, were predictive of a diagnosis of dementia with age being the strongest predictive factor.Study Supported by:Funding/Support: IIRG-09-133014 from the Alzheimer’s Association; 189 10276/8/9/2011 from the ESPA-EU program Excellence Grant (ARISTEIA) which is co-funded by the European Social Fund and Greek National resources; and Y2β/o.51657/14.4.2009 from the Ministry fo...
Source: Neurology - April 17, 2017 Category: Neurology Authors: Sakka, P., Kosmidis, M., Yannakoulia, M., Dardiotis, E., Hadjigeorgiou, G., Scarmeas, N. Tags: Aging and Dementia: Epidemiologic Studies Source Type: research

Predictive Variables of Cognitive Dysfunction in Patients with Lupus (P1.340)
Conclusions:Duration of disease and low educational level are predictors of CD in patients with SLE. Depression and anxiety did not influence cognitive performance. Although cardiovascular comorbidity is a risk factor for dementia in general population, those variables might play a minor role in SLE patients.Study Supported by:Coordenação de Aperfeiçoamento de Pessoal de Nível Superior (CAPES) and São Paulo Research Foundation (FAPESP) (grant #2015/08833-7) supported this study.Disclosure: Dr. Alessi has nothing to disclose. Dr. Dutra Antonio has nothing to disclose. Dr. Maria has nothing...
Source: Neurology - April 17, 2017 Category: Neurology Authors: Alessi, H., Dutra, L. A., Maria, L., Xavier, P., Couce, P., Kayser, C., Barsottini, O. Tags: CNS Inflammatory Diseases and Differential Diagnosis I Source Type: research

Elevated cerebrospinal fluid total Tau levels reflects predominant cortical involvement in Alzheimers disease (P1.093)
Conclusions:Elevated CSF Tau levels in AD patients could be surrogate biomarker for AD subtypes with predominant early cortical symptoms and atrophy. There is a need for a systematic prospective unbiased follow-up to see if rapid clinical progression in AD is related to elevated T-Tau and distinct AD subtypes.Disclosure: Dr. Pillai has nothing to disclose. Dr. Khrestian has nothing to disclose. Dr. Bekris has nothing to disclose. Dr. Safar has nothing to disclose. Dr. Leverenz has received personal compensation for activities with Axovant, GE Healthcare and Navidea Biopharmaceuticals as a consultant.
Source: Neurology - April 17, 2017 Category: Neurology Authors: Pillai, J., Khrestian, M., Bekris, L., Safar, J., Leverenz, J. Tags: Aging and Dementia: Biomarkers Source Type: research

Association between frequency of sleep medication use and brain morphology (P3.058)
Conclusions:This is the first study to examine the association between frequency of sleep medication use and brain morphology in a healthy group of older adults. Metabolic effects or a possible neurotoxicity could play a role to the observed associations.Study Supported by:NIH R01AG038465-02NIH R01AG026158-07Research programs of excellence IKY/SIEMENS for Angeliki Tsapanou, Nikolao ScarmeaDisclosure: Dr. Tsapanou has nothing to disclose. Dr. Gu has nothing to disclose. Dr. Haider has nothing to disclose. Dr. Stern has received personal compensation for activities with Takeda, Axovant, and Eli Lilly and Company as an adviso...
Source: Neurology - April 17, 2017 Category: Neurology Authors: Tsapanou, A., Gu, Y., Haider, L., Sakhardande, J., Scarmeas, N., Stern, Y. Tags: Sleep Disruption and Medical Co-Morbidities Source Type: research

A Brief Dementia Screening Test in South Africa: Results from the Health and Aging Longitudinal Study of an INDEPTH community (HAALSI) (P4.191)
Conclusions:There is a potentially protective and long-lasting impact of secondary school education on cognitive status later in life in this setting. Using a brief screening test in this relatively poor cohort of older South Africans, patterns of low cognition are similar to those in the USA and other countries.Study Supported by:The National Institute on Aging at the National Institute of Health (NIH) (1P01AG041710-01A1; 1R01AG051144–01; 3U54HG006938-03S1). F. Mateen is supported by a subgrant of P30AG024409 from the NIH for the Harvard Center for Global Demography and Aging. The Agincourt HDSS was supported by the...
Source: Neurology - April 17, 2017 Category: Neurology Authors: Mateen, F., Jennings, E., Montana, L., Wagner, R., Kahn, K., Tollman, S., Berkman, L. Tags: Behavioral and Cognitive Neurology: Neurodegenerative Disorders Source Type: research