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They Were Cigarette Smokers. Then a Stroke Vanquished Their Addiction.
Patients whose brain injury coincidentally relieved their nicotine cravings may help unravel the neural underpinnings of addiction, a new study suggests.
Source: NYT Health - June 13, 2022 Category: Consumer Health News Authors: Benjamin Mueller Tags: Brain Stroke Nature Neuroscience (Journal) Smoking and Tobacco Addiction (Psychology) your-feed-science Source Type: news

Nicotine suppresses central post-stroke pain via facilitation of descending noradrenergic neuron through activation of orexinergic neuron
In this study, we evaluated whether nicotine could suppress BCAO-induced mechanical allodynia through the activation of orexinergic neurons. Mice were subjected to BCAO for 30 min. Mechanical hypersensitivity was assessed by the von Frey test. BCAO mice showed hypersensitivity to mechanical stimuli three days after BCAO surgery. The intracerebroventricular injection of nicotine suppressed BCAO-induced mechanical hypersensitivity in a dose-dependent manner. These effects were inhibited by α7 or α4β2-nicotinic receptor antagonists. After nicotine injection, the level of c-fos, a neuronal activity marker, increased in the ...
Source: European Journal of Pharmacology - January 27, 2023 Category: Drugs & Pharmacology Authors: Kazuo Nakamoto Wataru Matsuura Shogo Tokuyama Source Type: research

Oversleeping: The Effects and Health Risks of Sleeping Too Much
This article originally appeared on the Amerisleep blog. Rosie Osmun is the Creative Content Manager at Amerisleep, a progressive memory foam mattress brand focused on eco-friendly sleep solutions. Rosie writes more posts on the Amerisleep blog about the science of sleep, eco-friendly living, leading a healthy lifestyle and more. -- This feed and its contents are the property of The Huffington Post, and use is subject to our terms. It may be used for personal consumption, but may not be distributed on a website.
Source: Healthy Living - The Huffington Post - January 29, 2016 Category: Consumer Health News Source Type: news

Assessment of the relationship between platelet reactivity, vascular risk factors and gender in cerebral ischaemia patients.
CONCLUSIONS: There are no differences between platelet reactivity and the incidence of aspirin resistance in patients with stroke and TIA. Male gender and smoking are associated with greater reactivity of platelets and more frequent occurrence of acetylsalicylic acid resistance in patients with cerebral ischaemia. CLINICAL IMPLICATIONS: Dual antiplatelet therapy or clopidogrel treatment should be considered in smoking males with cerebral ischaemia due to the high risk of aspirin inefficiency. PMID: 31343071 [PubMed - as supplied by publisher]
Source: Neurologia i Neurochirurgia Polska - July 24, 2019 Category: Neurology Authors: Wiśniewski A, Sikora J, Filipska K, Kozera G Tags: Neurol Neurochir Pol Source Type: research

Behind the Headlines 2014 Quiz of the Year
In 2014, Behind the Headlines covered more than 500 health stories that made it into the mainstream media. Test your knowledge of 2014's health news with our month-by-month quiz. If you've been paying attention, you should find this quiz both easy and fun. Answers are at the foot of the page (no peeking!).   In January 2014's health news... What was said to help make bones stronger? 1) Swimming 2) Marriage 3) Listening to classical music Warnings were issued about the possible return of what? 1) Swine flu 2) The Black Death 3) Smallpox   In February 2014's health news... What activity was said to lower your ...
Source: NHS News Feed - December 29, 2014 Category: Consumer Health News Tags: Special reports Medical practice Source Type: news

Behind the Headlines 2016 Quiz of the Year
In 2014, Behind the Headlines has covered more than 500 health stories that made it into the mainstream media. If you've been paying attention you should find this quiz easy and fun. Why not test your knowledge of 2014's health news with our month-by-month quiz? Answers are at the foot of the page (no peeking!).   In January 2016's health news... In a controversial study, monkeys were genetically engineered to develop what disorder? 1) Sex addiction 2) Bi-polar disorder 3) Autism In a similarly controversial study, what psychological condition was dismissed as a "myth" 1) Seasonal affective disorder...
Source: NHS News Feed - December 5, 2016 Category: Consumer Health News Tags: Special reports Source Type: news

Tar level of cigarettes smoked and risk of smoking-related diseases.
CONCLUSIONS: Despite evidence that smokers substantially compensate for reduced cigarette yields, the results clearly show lower risks in lower tar smokers. Limitations of the evidence are discussed, but seem unlikely to affect this conclusion. PMID: 29488428 [PubMed - as supplied by publisher]
Source: Inhalation Toxicology - March 2, 2018 Category: Respiratory Medicine Tags: Inhal Toxicol Source Type: research

The Case Files: Unusual Headache
By Al-Hashimi, Siddhartha DO; Leavens, John MD A 23-year-old woman with a history of migraine headaches presented to the emergency department for a different-than-usual headache. She had a six-day history of intermittent headaches. The onset was at rest, and there was no history of trauma.   The headache was located behind her left eye, and it radiated into the posterior portion of her head. She characterized it as being 8/10 in intensity. Bright lights were reported as an exacerbating factor. The headache was associated with nausea and multiple episodes of emesis. She had 10 episodes of vomiting the evening prior to arri...
Source: The Case Files - June 5, 2014 Category: Emergency Medicine Tags: Blog Posts Source Type: research

3 Key Nutrients For Better Brainpower
By Nancy Christie When it comes to what we eat, we usually worry more about our waistlines than our wisdom. But a diet that contains a wide assortment of healthy foods and nutrients doesn’t just benefit your body; it may protect your brain from cognitive decline as you age. In order to defend against a variety of age-related conditions that can impair your memory and the general functioning of your brain, a good first step is to concentrate on incorporating three nutrients into your diet: omega-3 fatty acids, flavonoids and vitamin E. 1. Omega-3 Fatty Acids for Brain Volume For your memory to function smoothly, your br...
Source: Healthy Living - The Huffington Post - April 26, 2015 Category: Consumer Health News Source Type: news

Damage to the insula leads to decreased nicotine withdrawal during abstinence
ConclusionsCurrent smokers with damage to their insular cortex brain region appear to experience fewer and less severe tobacco withdrawal symptoms, and appear to be less likely to require nicotine replacement therapy during hospitalization, compared with smokers with non‐insular damage. These findings support the potential role of the insular cortex in regulating withdrawal during abstinence, a motivator responsible for the maintenance of addictive behaviors.
Source: Addiction - September 8, 2015 Category: Addiction Authors: Amir Abdolahi, Geoffrey C. Williams, Curtis G. Benesch, Henry Z. Wang, Eric M. Spitzer, Bryan E. Scott, Robert C. Block, Edwin Wijngaarden Tags: Research Report Source Type: research

More Than A Third Of Americans Don't Get Enough Sleep
We spend about one-third of our life doing it, but more than one in three Americans still aren’t getting enough sleep, according to a new government report.  In their first study of self-reported sleep length, the U.S. Centers for Disease Control and Prevention found that 34.8 percent of American adults are getting less than seven hours of sleep -- the minimum length of time adults should sleep in order to reduce risk of obesity, diabetes, high blood pressure, stroke, mental distress, coronary heart disease and early death. In total, an estimated 83.6 million adults in the U.S. are sleep deprived, the CDC repor...
Source: Science - The Huffington Post - February 18, 2016 Category: Science Source Type: news

Mental and Physical Health Conditions in US Combat Veterans: Results From the National Health and Resilience in Veterans Study.
Conclusions: Compared to noncombat veterans in the United States, combat veterans have elevated rates of PTSD, suicide attempt, stroke, and chronic pain independent of other sociodemographic, military, and mental health factors. Younger combat veterans have elevated rates of PTSD, suicidal ideation, and migraine headaches, while older combat veterans have elevated rates of heart disease and heart attack. These results characterize the population-based burden of mental and physical health conditions in combat veterans. They further underscore the importance of age- and condition-sensitive screening, monitoring, and treatmen...
Source: The Primary Care Companion for CNS Disorders - June 30, 2017 Category: Primary Care Tags: Prim Care Companion CNS Disord Source Type: research

CNS Summit 2017 Abstracts of Poster Presentations
Conclusion: This novel technology discriminates and quantifies subtle differences in behavior and neurological impairments in subjects afflicted with neurological injury/disease. KINARM assessments can be incorporated into multi-center trials (e.g., monitoring stroke motor recovery: NCT02928393). Further studies will determine if KINARM Labs can demonstrate a clinical effect with fewer subjects over a shorter trial period. Disclosures/funding: Dr. Stephen Scott is the inventor of KINARM and CSO of BKIN Technologies.   Multiplexed mass spectrometry assay identifies neurodegeneration biomarkers in CSF Presenter: Chelsky...
Source: Innovations in Clinical Neuroscience - November 1, 2017 Category: Neuroscience Authors: ICNS Online Editor Tags: Assessment Tools biomarkers Cognition Current Issue Drug Development General Genetics Medical Issues Neurology Patient Assessment Psychopharmacology Scales Special Issues Supplements Trial Methodology clinical trials CNS Su Source Type: research

Cardiovascular risk factors in patients with combined central retinal vein occlusion and cilioretinal artery occlusion: Case report
AbstractRationale:To analyze cardiovascular risk factors and comorbidity of acute unilateral visual loss due to combined central retinal vein occlusion (CRVO) and cilioretinal artery occlusion (CLRAO).Patient concerns:Among patients with retinal vein or artery occlusion hospitalized at the Department of Ophthalmology between January 2011 and August 2017, subjects with combined CRVO/CLRAO were selected. All of them underwent ophthalmologic and cardiologic examination, including fluorescein angiography, optical coherence tomography, 12-lead electrocardiogram, transthoracic and transesophageal echocardiography, carotid Dopple...
Source: Medicine - January 1, 2018 Category: Internal Medicine Tags: Research Article: Clinical Case Report Source Type: research

Hookah smoking raises cardiovascular risk comparable to traditional cigarette smoking, study finds
This study is believed to be the first to investigate the effects of hookah smoking on stiffening of the arteries. Studies have shown that as cigarette use continues to decline, hookah smoking is rising, especially among youth and particularly among college students.“We know that flavored tobacco products are frequently the first kind of tobacco product used by youth,” Rezk-Hanna said. “One of the major issues with hookah is the fact that the tobacco is flavored with fruit, candy and alcohol flavors, making hookah the most popular flavored tobacco produc t among this audience.”According to the Food and Drug Admini...
Source: UCLA Newsroom: Health Sciences - August 2, 2018 Category: Universities & Medical Training Source Type: news