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12 Innovations That Will Change Health Care and Medicine in the 2020s
Pocket-size ultrasound devices that cost 50 times less than the machines in hospitals (and connect to your phone). Virtual reality that speeds healing in rehab. Artificial intelligence that’s better than medical experts at spotting lung tumors. These are just some of the innovations now transforming medicine at a remarkable pace.
No one can predict the future, but it can at least be glimpsed in the dozen inventions and concepts below. Like the people behind them, they stand at the vanguard of health care. Neither exhaustive nor exclusive, the list is, rather, representative of the recasting of public health and medic...
Source: TIME: Health - October 25, 2019 Category: Consumer Health News Authors: TIME Staff Tags: Uncategorized HealthSummit19 technology Source Type: news
Full-Thickness Skin Grafts and Quilting Sutures for the Reconstruction of Internal Nasal Lining
Facial Plast Surg 2020; 36: 297-304 DOI: 10.1055/s-0040-1713116Restoration of the inner nasal lining is an essential factor in successful nasal reconstruction. Among various methods, free full-thickness skin grafting represents a readily available and feasible technique. A prerequisite for success is a secure and immobile fixation to the undersurface of the nourishing forehead flap. This retrospective study aims to evaluate the results of multiple quilting sutures to secure free full-thickness skin grafts for the reconstruction of the inner nasal lining in partial and extended nasal reconstruction. Between February 1, 2015...
Source: Facial Plastic Surgery - June 16, 2020 Category: Cosmetic Surgery Authors: Gostian, PD Dr. med. Antoniu-Oreste Balk, Dr. med. Matthias Stegmann, Dr. med. Achim Iro, Prof. Dr. med. Dr. h.c. Heinrich Wurm, Prof. Dr. med. Jochen Tags: Original Research Source Type: research
Nicotine-induced adrenal beta-arrestin1 upregulation mediates tobacco-related hyperaldosteronism leading to cardiac dysfunction.
CONCLUSION: Adrenal βarrestin1 upregulation is one of the mechanisms by which tobacco compounds, like nicotine, promote cardio-toxic hyperaldosteronism in vitro and in vivo. Thus, adrenal βarrestin1 represents a novel therapeutic target for tobacco-related heart disease prevention or mitigation.
PMID: 32547713 [PubMed]
Source: World Journal of Cardiology - May 25, 2020 Category: Cardiology Authors: Cora N, Ghandour J, Pollard CM, Desimine VL, Ferraino KE, Pereyra JM, Valiente R, Lymperopoulos A Tags: World J Cardiol Source Type: research
Adultcamlover Review, The Cam Girl Website
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Source: Journal of Clinical and Aesthetic Dermatology - December 5, 2020 Category: Dermatology Authors: Buya Bat Tags: Uncategorized Source Type: research
Secondhand Smoke Exposure Among Nonsmoking Adults: United States, 2015-2018.
This report examines the prevalence of SHS exposure among nonsmoking U.S. adults in 2015-2018 based on blood levels of cotinine, a metabolite of nicotine. Trends in SHS exposure are also presented.
PMID: 33541515 [PubMed - in process]
Source: NCHS data brief - February 6, 2021 Category: American Health Tags: NCHS Data Brief Source Type: research
Antithrombotic Treatment for Peripheral Arterial Occlusive Disease
CONCLUSION: Antiplatelet therapy should only be intensified for a limited time, or if the risk of ischemia is high. Before and during intensified antiplatelet therapy, the risk of bleeding should be assessed and weighed against the risk of ischemia. No validated score is available to estimate the risk of hemorrhagic complications in patients with PAOD. New antithrombotic therapies should not be used indiscriminately, but should rather be reserved for selected groups of patients.PMID:33734081 | DOI:10.3238/arztebl.m2021.0157
Source: Deutsches Arzteblatt International - March 18, 2021 Category: General Medicine Authors: David Hardung Andrea Behne Mehmet Boral Carsten Giesche Ralf Langhoff Source Type: research
COVID-19 Associated Reversible Cerebral Vasoconstriction Syndrome Successfully Treated with Nimodipine and Aspirin
A 31-year-old sexually active, non-smoker female with a past medical history of spina-bifida and idiopathic thoracolumbar scoliosis status post hardware spinal fusion surgery five years ago presented with a one-day history of severe holocranial headaches associated with nausea and visual changes. A thorough neurological examination was intact. She complained of mild cough as well. She had a positive nasopharyngeal swab for SARS-CoV-2 on RT-PCR assay. A comprehensive drug screen including amphetamines, cocaine, nicotine, alcohol, and ecstasy as well as a pregnancy test were negative; coagulation profile was within normal limits.
Source: Journal of Stroke and Cerebrovascular Diseases - April 12, 2021 Category: Neurology Authors: Tarab Mansoor, Ali A. Alsarah, Hossein Mousavi, Javed Elyias, Tarun Girotra, Omar Hussein Tags: Case Report Source Type: research
Temporal proteomic changes induced by nicotine in human cells: A quantitative proteomics approach
J Proteomics. 2021 Apr 22:104244. doi: 10.1016/j.jprot.2021.104244. Online ahead of print.ABSTRACTNicotine is a prominent active compound in tobacco and many smoking cessation products. Some of the biological effects of nicotine are well documented in in vitro and in vivo systems; however, nominal data are available concerning the time-dependent changes on protein and phosphorylation events in response to nicotine. Here, we profiled the proteomes of SH-SY5Y and A549 cell lines subjected to acute (15 min, 1 h and 4 h) or chronic (24 h, 48 h) nicotine exposures. We used sample multiplexing (TMTpro16) and quantified more than...
Source: Journal of Proteomics - April 25, 2021 Category: Biochemistry Authors: Jos é Navarrete-Perea Steven P Gygi Joao A Paulo Source Type: research
Nicotine Exposure Along with Oral Contraceptive Treatment in Female Rats Exacerbates Post-cerebral Ischemic Hypoperfusion Potentially via Altered Histamine Metabolism
AbstractSmoking-derived nicotine (N) and oral contraceptives (OCs) synergistically exacerbate ischemic brain damage in the female, and the underlying mechanisms remain elusive. Our published study showed that N toxicity is exacerbated by OC via altered mitochondrial electron transport chain function. Because mitochondria play an important role in cellular metabolism, we investigated the global metabolomic profile of brains of adolescent and adult female Sprague-Dawley rats exposed to N with or without OC (N+/ −OC). Rats were randomly exposed to saline or N+/−OC for 16–21 days followed by random allocation into two c...
Source: Translational Stroke Research - September 6, 2021 Category: Neurology Source Type: research
Non-linear dose-response relation between urinary levels of nicotine and its metabolites and cognitive impairment among an elderly population in China
CONCLUSIONS: Urinary levels of OHCotGluc, NNO or ∑Nic exhibited a non-linear dose-response relationship with cognitive function in the urban elderly.PMID:34461317 | DOI:10.1016/j.ecoenv.2021.112706
Source: Ecotoxicology and Environmental Safety - August 30, 2021 Category: Environmental Health Authors: Tian Li Wei Liu Ya-Jun Yue Shao-You Lu Lu-Lin Nie Xi-Fei Yang Qing-Qing Zhu Bo Zhu Lu Wang Fei-Qi Zhu Li Zhou Jia-Fei Zhang Er-Wei Gao Kai-Wu He Li Liu Fang Ye Jian-Jun Liu Jing Yuan Lin Wang Source Type: research
Smoking cessation adherence:recurrent cardiovascular events after five years of first manifestation
ConclusionsSmoking cessation after a first cardiovascular event should be a key objective for both patients and physicians to reduce the risk for recurrent vascular events. More efforts are needed to maintain smoking cessation in patients at very high cardiovascular risk.Key messagesSmoking cessation consultation can increase adherence to smoking cessation and helps in reducing the excess risk of recurrent cardiovascular events.Smoking is highly addictive and cessation can be extremely difficult, even after a life-threatening vascular event.
Source: The European Journal of Public Health - October 20, 2021 Category: General Medicine Source Type: research
