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Total 230 results found since Jan 2013.

Intracranial dermoid cyst rupture-related brain ischemia: Case report and hemodynamic study
Rationale: Spontaneous rupture of intracranial dermoid cyst is a rare but serious clinical event that can result in cerebral ischemia. Cerebral vasospasm and vasculitis are considered as potential mechanisms of dermoid cyst rupture-related cerebral ischemia. However, the hemodynamic mechanisms between cerebral ischemia and dermoid cyst rupture are not well known. Patient concerns: A 55-year-old, right-handed man was admitted to our hospital with sudden receptive aphasia and right-sided hypoalgesia. Brain magnetic resonance imaging (MRI) revealed a ruptured dermoid cyst and watershed infarcts in the left hemisphere. Then b...
Source: Medicine - January 1, 2017 Category: Internal Medicine Tags: Research Article: Clinical Case Report Source Type: research

Recurrent cryptogenic stroke in young adult linked to congenital left ventricular diverticulum
A 47-year-old man had an acute ischemic stroke (IS); brain MRI revealed multiple silent old IS (figure 1A). A comprehensive workup, including prolonged cardiac monitoring (cumulated duration of 25 days) and cardiac transthoracic/transesophageal echography, was negative. Eleven months later, despite statin and aspirin therapy, a new symptomatic embolic IS of undetermined source occurred (figure 1B). Cardiac MRI1 revealed a left apical dyskinetic saccular evagination (figure 2, A–C) consistent with a congenital left ventricular diverticulum confirmed on left ventriculography (figure 2D) and the presumed source of recur...
Source: Neurology - November 13, 2016 Category: Neurology Authors: Gaillard, N., Targosz, F., Bertrand, J. L., Sablot, D., Bensalah, Z. M. Tags: Stroke in young adults, Cardiac, Embolism, Infarction NEUROIMAGES Source Type: research

Edaravone offers neuroprotection for acute diabetic stroke patients
ConclusionEdaravone represents a promising neuroprotectant against cerebral ischemic injury in diabetic patients.
Source: Irish Journal of Medical Science - October 31, 2016 Category: Journals (General) Source Type: research

Simultaneous Bilateral Carotid Stenting for Symptomatic Bilateral High-Grade Carotid Stenosis: A Retrospective Clinical Investigation.
CONCLUSIONS Compared to SAMM, we found that SBCAS was more effective and safer for symptomatic bilateral high-grade CS. PMID: 27542158 [PubMed - as supplied by publisher]
Source: Medical Science Monitor - August 21, 2016 Category: Research Tags: Med Sci Monit Source Type: research

A Young Woman with Ischemic Stroke: Should We Pay More Attention to Varicella Zoster Infection?
In conclusion, VZV vasculopathy needs to be considered in young adults with stroke. A high index of suspicion and early treatment seem to be important to minimize morbidity and mortality. Anticoagulation should probably be avoided in stroke associated with VZV vasculopathy.Case Rep Neurol 2016;8:145–150
Source: Case Reports in Neurology - July 7, 2016 Category: Neurology Source Type: research

STEMI vs NSTEACS management trends in non-invasive hospital.
CONCLUSION: NSTEACS patients in western province of KSA present at an older age are mostly males and have higher prevalence of hypertension and hyperlipidemia compared with STEMI patients. It is therefore important to identify patients with high-risk profile and put implement measures to reduce these factors. PMID: 27543475 [PubMed - in process]
Source: Indian Heart J - June 30, 2016 Category: Cardiology Authors: Kinsara AJ, Alrahimi JS, Yusuf OB Tags: Indian Heart J Source Type: research

Migraines linked to increased heart disease risk in women
Conclusion This study shows a strong link between migraine and cardiovascular disease, extending the link already found between migraine and stroke. However, many questions remain. We don't know if the results are relevant to men who have migraines, as all the people in the study were women. We also don't know if the results apply to non-white populations, as most of the women in the study were white. Previous studies on stroke have shown that the group at highest risk is who get an "aura" before a migraine – sensation(s) that tells them the migraine is on its way. But this study did not ask people about aura...
Source: NHS News Feed - June 1, 2016 Category: Consumer Health News Tags: Heart/lungs Neurology Source Type: news

Statins in stroke prevention: present and future.
CONCLUSION: Traditionally, there has been no clear data demonstrating that adding other lipid-modifying drugs to statins results in a further decrease in stroke or other cardiovascular event, but now things have changed and future directions include combinations with ezetimibe and new treatments such as PCSK9 inhibitors. Only time will tell the real roll of these new promising non-statin lipid-modifying therapies on stroke prevention. PMID: 27160755 [PubMed - as supplied by publisher]
Source: Current Pharmaceutical Design - May 9, 2016 Category: Drugs & Pharmacology Authors: Castilla-Guerra L, Del Carmen Fernandez-Moreno M, Colmenero-Camacho MA Tags: Curr Pharm Des Source Type: research

The contemporary management of intracranial atherosclerotic disease.
Authors: Leng X, Wong KS, Leung TW Abstract Intracranial atherosclerotic disease is the most common cause of cerebral vasculopathy and an important stroke etiology worldwide, with a higher prevalence in Asian, Hispanic and African ethnicities. Symptomatic intracranial atherosclerotic disease portends a recurrent stroke risk as high as 18% at one year. The key to secondary prevention is an understanding of the underlying stroke mechanism and aggressive control of conventional cardiovascular risks. Contemporary treatment includes antiplatelet therapy, optimal glycemic and blood pressure control, statin therapy and li...
Source: Expert Review of Neurotherapeutics - April 18, 2016 Category: Neurology Tags: Expert Rev Neurother Source Type: research

Endovascular Therapy for Chronic Mesenteric Ischemia
Opinion statement Chronic mesenteric ischemia (CMI) most commonly occurs as a consequence of multivessel atherosclerotic disease of the mesenteric vasculature. Risk factors include smoking, hypertension, dyslipidemia, and advanced age, and women are more commonly affected than men. The clinical presentation of CMI is characterized by postprandial abdominal pain and weight loss. Left untreated, patients often develop severe malnutrition. Current consensus guidelines recommend secondary prevention medications such as statins and aspirin for all patients with known atherosclerosis to reduce the risk of stroke and MI...
Source: Current Treatment Options in Cardiovascular Medicine - April 14, 2016 Category: Cardiology Source Type: research

Use of aspirin and statins for the primary prevention of myocardial infarction and stroke in patients with human immunodeficiency virus infection
This retrospective, cross-sectional study evaluated whether HIV-infected patients received aspirin and statins for the primary prevention of myocardial infarction and stroke. Among the 258 patients included, 50.4% (n = 130/258) of the patients had a high risk of myocardial infarction and 14% (n = 36/258) of stroke. Overall, 43.1% (n = 56/130) and 50% (n = 18/36) of the patients were prescribed aspirin for the primary prevention of myocardial infarction and stroke, respectively. Among the patients who required statin therapy, 42.5% (n = 34/80) and 37.1% (n = 13/35) of patients received it for the primary prevention of myoca...
Source: International Journal of STD and AIDS - April 6, 2016 Category: Global & Universal Authors: Park, T. E., Yusuff, J., Sharma, R. Tags: Original research articles Source Type: research

Aggressive Medical Management for ICAD: A Comparison to the SAMMPRIS Trial (P1.174)
Conclusions:In a single center observational cohort study, we found that AMM in symptomatic ICAD yielded higher rates of recurrent stroke at 30 days when compared to the SAMMPRIS trial. This indicates that it may be more difficult to replicate the AMM and lifestyle modifications that were implemented in the SAMMPRIS trial and warrants further investigation.Disclosure: Dr. Sangha has nothing to disclose. Dr. Ansari has nothing to disclose. Dr. Bernstein has received personal compensation for activities with Boehringer Ingelheim Pharmaceuticals, Inc., and Pfizer Inc. as a speaker/advisory board member. Dr. Corado has nothing...
Source: Neurology - April 3, 2016 Category: Neurology Authors: Sangha, R., Ansari, S., Bernstein, R., Corado, C., Curran, Y., Ruff, I., Prabhakaran, S. Tags: Cerebrovascular Disease: Risk Factors and Prevention Source Type: research

A Case of Transient Global Amnesia: A Review and How It May Shed Further Insight into the Neurobiology of Delusions
Conclusion In closing, our patient’s episode of TGA combined with her emotional and perceptual response lends credence to the proposal of a “fear/paranoia” circuit in the genesis of paranoid delusions—a circuit incorporating amygdala, frontal, and parietal cortices. Here, neutral or irrelevant stimuli, thoughts, and percepts come to engender fear and anxiety, while dysfunction in frontoparietal circuitry engenders inappropriate social predictions and maladaptive inferences about the intentions of others.[54] Hippocampus relays information about contextual information based on past experiences and the current situat...
Source: Innovations in Clinical Neuroscience - April 1, 2016 Category: Neuroscience Authors: ICN Online Editor Tags: Anxiety Disorders Behavioral and Cognitive Neurology Case Report Cognition Current Issue Dementia Medical Issues Neurologic Systems and Symptoms Psychiatry Schizophrenia delusions hippocampus neurobiology Transient global amnesia Source Type: research

Better than Aspirin for Your Heart
If you’ve been diagnosed with heart disease, the chances are you’ve been told to take low-dose aspirin every day as a preventative measure against heart attack and stroke. It’s most commonly prescribed for patients with congestive heart failure. This is the inability of your heart to pump as much blood as your body needs. And this is a big worry to me, because there is very little evidence that aspirin helps. In fact, regular use of aspirin — even baby aspirin — can do you more harm than good. Common Aspirin Beliefs The idea is that aspirin thins the blood, making it easier to pump.  It is also s...
Source: Al Sears, MD Natural Remedies - April 1, 2016 Category: Complementary Medicine Authors: Al Sears Tags: Heart Health Source Type: news

Pulse Pressure and Risk for Cardiovascular Events in Patients With Atherothrombosis From the REACH Registry
BackgroundPulse pressure (PP) provides valuable prognostic information in specific populations, but few studies have assessed its value on cardiovascular outcomes in a broad, worldwide population.ObjectivesThe aim of this study was to determine whether PP is associated with major adverse cardiovascular outcomes, independently of mean arterial pressure.MethodsParticipants from the international REACH (Reduction of Atherothrombosis for Continued Health) registry, which evaluates subjects with clinical atherothrombotic disease or risk factors for its development, were examined. Those with incomplete 4-year follow-up or PP dat...
Source: Journal of the American College of Cardiology: Cardiovascular Imaging - January 25, 2016 Category: Radiology Source Type: research