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What the Science Says About the Health Benefits of Vitamins and Supplements
From multivitamins and melatonin to fiber and fish oil, Americans who are trying to boost their health and immunity have a plethora of supplements to choose from. An estimated 58% of U.S. adults ages 20 and over take dietary supplements, according to the U.S. Centers for Disease Control and Prevention, and the supplement industry is valued at more than $30 billion a year. Supplement use has been growing rapidly over the past few decades along with the wellness industry. “The popular belief is that a supplement is going to be helpful for promoting health,” says Fang Fang Zhang, a professor at Tufts University&rs...
Source: TIME: Health - April 28, 2022 Category: Consumer Health News Authors: Sandeep Ravindran Tags: Uncategorized Diet & Nutrition healthscienceclimate Source Type: news

Properties and reactivity of the folic acid and folate photoproduct 6-formylpterin
Free Radic Biol Med. 2021 May 6:S0891-5849(21)00283-5. doi: 10.1016/j.freeradbiomed.2021.05.002. Online ahead of print.ABSTRACTFolates (vitamin B9) are essential components of our diet and our gut microbiota. They are omnipresent in our cells and blood. Folates are necessary for DNA synthesis, methylation, and other vital bioprocesses. Folic acid (FA), as the synthetic form of folates, is largely found in supplements and fortified foods. FA and folate drugs are also extensively used as therapeutics. Therefore, we are continuously exposed to the pterin derivatives, and their photo-degradation products, such as 6-formylpteri...
Source: Free Radical Biology and Medicine - May 9, 2021 Category: Biology Authors: Goossens Jean-Fran çois Xavier Thuru Christian Bailly Source Type: research

Urine Arsenic and Arsenic Metabolites in U.S. Adults and Biomarkers of Inflammation, Oxidative Stress, and Endothelial Dysfunction: A Cross-Sectional Study
Conclusion: In a cross-sectional study of U.S. adults, we observed some positive associations of uAs and toenail As concentrations with biomarkers potentially relevant to CVD pathogenesis and inflammation, and evidence of a higher capacity to metabolize inorganic As was negatively associated with a marker of oxidative stress. https://doi.org/10.1289/EHP2062 Received: 14 April 2017 Revised: 13 November 2017 Accepted: 15 November 2017 Published: 15 December 2017 Address correspondence to S.F. Farzan, 2001 N. Soto St., Los Angeles, CA, 90032. Telephone: (323)-442-5101; Email: sffarzan@usc.edu Supplemental Material is ava...
Source: EHP Research - December 16, 2017 Category: Environmental Health Authors: Daniil Lyalko Tags: Research Source Type: research

Association of Serum Uric Acid with Increased Risk of Cancer among Hypertensive Chinese
This study included 20577 adult hypertensive patients with valid SUA measurements who participated in the China Stroke Primary Prevention Trial where subjects were randomly assigned to receive a double‐blind treatment of either 10mg enalapril (n=10286) or 10.8mg enalapril‐folic acid (n=10291). Subjects were prospectively followed for a median of 4.5 years. Cox proportional hazards models were used to calculate hazards ratios (HR) of cancer risk associated with SUA. A total of 232 participants developed cancer. SUA was independently associated with increased cancer risk in the enalapril group [HR: 1.12, (95% CI: 1.03‐...
Source: International Journal of Cancer - April 10, 2017 Category: Cancer & Oncology Authors: Juan Yang, Yupeng Wang, Qianqian Zhao, Xianglin Zhang, Xiaobin Wang, Xianhui Qin, Rong Zhang, Lin Shen, Xiaodong Jiang, Hua Jiang, Yu Lei, Binyan Wang, Jin Gu, Fan Fan Hou, Yong Huo, Wei Gao, Xiping Xu Tags: Research Article Source Type: research

3 reasons your child shouldn’t go “gluten-free” (unless your doctor says so)
Follow me at @drClaire There is a puzzling and worrisome new phenomenon that I am seeing as a pediatrician: parents who are putting their children on gluten-free diets. It’s puzzling because in the vast majority of cases it isn’t necessary — and it’s worrisome because, although parents are doing it because they think it’s healthy, a gluten-free diet can be very unhealthy for children. Gluten is a protein found in wheat, rye, barley, and some other grains. It’s in bread and other baked goods, cereals, pastas — and in many other foods in small amounts. For people with celiac disease, even those small amounts ca...
Source: New Harvard Health Information - June 7, 2016 Category: Consumer Health News Authors: Claire McCarthy, MD Tags: Children's Health Healthy Eating Parenting Source Type: news

FDA warns parents about arsenic in rice cereal
Follow me at @drClaire For years, rice cereal has been a go-to for parents when they start their babies on solid foods. It’s time to change that. In 2012, the Consumer Products Safety Commission (CPSC) issued a report warning about high levels of inorganic arsenic in rice and rice products. Rice plants are particularly good at absorbing arsenic from the soil, in particular because they grow in a lot of water. Inorganic arsenic is a common ingredient in pesticides and other products used in farming, and can linger in the soil for a long time after it is used. It can be poisonous. In high doses it is lethal, but even small...
Source: New Harvard Health Information - April 5, 2016 Category: Consumer Health News Authors: Claire McCarthy, MD Tags: Children's Health Parenting Safety Source Type: news

Effect of folic acid supplementation on cancer risk among adults with hypertension in China: A randomized clinical trial
This article is protected by copyright. All rights reserved.
Source: International Journal of Cancer - March 17, 2016 Category: Cancer & Oncology Authors: Xianhui Qin, Lin Shen, Rong Zhang, Youbao Li, Xiaobin Wang, Binyan Wang, Xiaodong Jiang, Hua Jiang, Yu Lei, Fan Fan Hou, Jin Gu, Yong Huo Tags: Research Article Source Type: research

Depression in the Elderly: A Common Condition That's Often Overlooked
When Suzette Santos, RN, a behavioral health nurse with the Visiting Nurse Service of New York (VNSNY), was assigned to the case of Grace*, an 89-year-old resident of Nassau County on Long Island, she had some idea what to expect. Suzette had cared for Grace a year earlier, as the elderly woman struggled to cope with depression brought on by the recent loss of her husband and lifelong partner. When Suzette reconnected with her patient this time, she could immediately see that Grace's depression had gotten worse. "She had lost a lot of weight -- about 20 pounds," Suzette recalls. "She had no interest in cooking or eating, ...
Source: Healthy Living - The Huffington Post - December 23, 2015 Category: Consumer Health News Source Type: news

Multidisciplinary approach and anesthetic management of a surgical cancer patient with methylene tetrahydrofolate reductase deficiency: a case report and review of the literature
Conclusions Neoplastic disease and related surgery followed by the administration of chemotherapeutic drugs alter the hemostatic balance in cancer patients. Those suspected of also having a thrombophilic disease require a thorough laboratory diagnostic workup, including a molecular analysis aimed at identifying the genetic mutation responsible for the hyperhomocysteinemia, as indicated. The case described in this report highlights the importance of a multidisciplinary approach that includes expertise in peri-operative anesthesia, surgery, oncology, and hematology.
Source: Journal of Medical Case Reports - August 20, 2015 Category: Journals (General) Source Type: research

Supplements That Save Lives And Bucks
I’m sure I don’t have to tell you about the high cost of medical care these days. The fact is that as costs continue to skyrocket, more and more Americans are driven into bankruptcy, because they cannot pay their medical bills. Too often, they even lose their homes. You may have even lost a neighbor to this disturbing trend. It may have even happened to you – although, I certainly hope not. That’s one reason I have always dedicated myself to keeping my patients out of hospitals – which often see patients as cash cows, instead of human beings. And a cornerstone of this philosophy has been based upon pr...
Source: Al Sears, MD Natural Remedies - June 3, 2015 Category: Complementary Medicine Authors: Dr. Al Sears Tags: Nutrition supplements vitamins Source Type: news

Incident Cancer in a Cohort of 3,247 Cancer Diagnosis Free Ischemic Stroke Patients
Conclusions: The annual rate of age-adjusted cancer incidence was higher among ischemic stroke patients compared with those in the general population. The odds of mortality were three folds higher among stroke survivors who developed incident cancer.Cerebrovasc Dis 2015;39:262-268
Source: Cerebrovascular Diseases - April 7, 2015 Category: Neurology Source Type: research

Incident Cancer in Stroke Survivors: Analysis of the Vitamin Intervention for Stroke Prevention (VISP) Trial (P5.114)
Conclusions: Incident cancer is not uncommon and is associated with lower survival among stroke survivors.Disclosure: Dr. Suri has nothing to disclose. Dr. Malik has nothing to disclose. Dr. Rodriguez has nothing to disclose. Dr. Nickles has nothing to disclose. Dr. Qureshi has nothing to disclose.
Source: Neurology - April 9, 2014 Category: Neurology Authors: Suri, M., Adil, M., Rodriguez, G., Chaudhry, S., Qureshi, A. Tags: Cerebrovascular Disease and Interventional Neurology: Epidemiology Source Type: research

Health maintenance in women.
Abstract The health maintenance examination is an opportunity to focus on disease prevention and health promotion. The patient history should include screening for tobacco use, alcohol misuse, intimate partner violence, and depression. Premenopausal women should receive preconception counseling and contraception as needed, and all women planning or capable of pregnancy should take 400 to 800 mcg of folic acid per day. High-risk sexually active women should be counseled on reducing the risk of sexually transmitted infections, and screened for chlamydia, gonorrhea, and syphilis. All women should be screened for huma...
Source: American Family Physician - January 1, 2013 Category: Primary Care Authors: Riley M, Dobson M, Jones E, Kirst N Tags: Am Fam Physician Source Type: research