Supplements That Save Lives And Bucks

I’m sure I don’t have to tell you about the high cost of medical care these days. The fact is that as costs continue to skyrocket, more and more Americans are driven into bankruptcy, because they cannot pay their medical bills. Too often, they even lose their homes. You may have even lost a neighbor to this disturbing trend. It may have even happened to you – although, I certainly hope not. That’s one reason I have always dedicated myself to keeping my patients out of hospitals – which often see patients as cash cows, instead of human beings. And a cornerstone of this philosophy has been based upon prescribing natural remedies and treatments – like vitamins, minerals and herbal supplements. Most physicians will tell you that you’re wasting your money when you take these natural substances. Some are well-meaning enough to tell you to change your diet so you can get your vitamins and minerals from your meals. But our food has been gutted of nutrients by over-processing and bad agricultural practices. Most will tell you that these supplements have no medical value at all. As well-meaning as they might be, most doctors simply cannot accept that natural remedies – many of which have been around for millennia – have been proven to help prevent heart attacks, strokes and countless other diseases. Medical school simply didn’t teach it to them. But I can tell you that nature has provided preventions and cures for every diseas...
Source: Al Sears, MD Natural Remedies - Category: Complementary Medicine Authors: Tags: Nutrition supplements vitamins Source Type: news

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A novel strategy of EGFR‑TKI combined chemotherapy in the treatment of human lung cancer with EGFR‑sensitive mutation. Oncol Rep. 2018 Jun 18;: Authors: Zhang L, Qi Y, Xing K, Qian S, Zhang P, Wu X Abstract The discovery of epidermal growth factor receptor (EGFR)‑sensitive mutations in non‑small cell lung cancer (NSCLC) and the successful clinical application of EGFR tyrosine kinase inhibitors (TKIs) have changed the regimen of lung cancer therapy from traditional cytotoxic chemotherapy to molecular‑targeted cancer therapy. However, the main limitation of EGFR‑TKI therapy is the hetero...
Source: Oncology Reports - Category: Cancer & Oncology Tags: Oncol Rep Source Type: research
Authors: Tamura H, Higa A, Hoshi H, Hiyama G, Takahashi N, Ryufuku M, Morisawa G, Yanagisawa Y, Ito E, Imai JI, Dobashi Y, Katahira K, Soeda S, Watanabe T, Fujimori K, Watanabe S, Takagi M Abstract Patient-derived tumor xenograft models represent a promising preclinical cancer model that better replicates disease, compared with traditional cell culture; however, their use is low-throughput and costly. To overcome this limitation, patient-derived tumor organoids (PDOs) were established from human lung, ovarian and uterine tumor tissues, among others, to accurately and efficiently recapitulate the tissue architecture...
Source: Oncology Reports - Category: Cancer & Oncology Tags: Oncol Rep Source Type: research
This study is aimed to investigate the association between EPHA3 expression and androgen receptor (AR) signaling and the potential mechanism. We determined mRNA and protein levels of EPHA3 and AR signaling‑related genes in the PCa cell line 22Rv1 by reverse transcription‑polymerase chain reaction (RT‑PCR) and western blotting, respectively. The EPHA3 mRNA and protein levels were both found to be elevated by dihydrotestosterone (DHT) hormone in a dose‑ and time‑dependent manner, as AR and prostate‑specific antigen (PSA) expression were increased. Similarly, EPHA3 protein levels were also increased in the PCa cel...
Source: Oncology Reports - Category: Cancer & Oncology Tags: Oncol Rep Source Type: research
SB225002 inhibits prostate cancer invasion and attenuates the expression of BSP, OPN and MMP‑2. Oncol Rep. 2018 Jun 18;: Authors: Xu M, Jaing H, Wang H, Liu J, Liu B, Guo Z Abstract The mechanisms of malignant cell metastasis to secondary sites are complex and multifactorial. Studies have demonstrated that small integrin‑binding ligand N‑linked glycoproteins (SIBLINGs), particularly bone sialoprotein (BSP) and osteopontin (OPN), are involved in neoplastic growth and metastasis. SIBLINGs promote malignant cell invasion and metastasis by enhancing matrix metalloproteinase 2 (MMP‑2) and MMP‑9 ex...
Source: Oncology Reports - Category: Cancer & Oncology Tags: Oncol Rep Source Type: research
In conclusion, CAF‑derived HGF promotes angiogenesis, VM and mosaic vessel formation via PI3K/AKT and ERK1/2 signaling in gastric cancer and HGF may serve as a potential therapeutic target for cancer anti‑vascular treatment. PMID: 29917165 [PubMed - as supplied by publisher]
Source: Oncology Reports - Category: Cancer & Oncology Tags: Oncol Rep Source Type: research
Authors: Wang Y, Lin X, Fu X, Yan W, Lin F, Kuang P, Luo Y, Lin E, Hong X, Wu G Abstract Thyroid cancer is one of the most common malignant tumors of the endocrine system. Among all thyroid cancers, papillary thyroid carcinoma (PTC) is the most common type. The BRAF-activated non-coding RNA (BANCR) is a 693-bp nucleotide transcript which was first identified in melanoma. However, the role of BANCR in the development of thyroid cancer remains unclear. Therefore, the present study investigated the potential involvement of BANCR in the development of thyroid cancer in vitro using patient tissue samples and a pane...
Source: Oncology Reports - Category: Cancer & Oncology Tags: Oncol Rep Source Type: research
Authors: Sun Y, Jiang F, Pan Y, Chen X, Chen J, Wang Y, Zheng X, Zhang J Abstract X‑box‑binding protein 1 (XBP1) contributes to various types of cancer including breast, bladder cancer and esophageal squamous cell carcinoma. The aim of the study was to examine the metastatic role of XBP1 in oral squamous cell carcinoma (OSCC), and identify possible downstream molecules. Immunohistochemical staining was conducted on tissue microarrays comprising 96 OSCC cases to determine the expression level of XBP1 and analyze its association with metastasis, clinicopathological characteristics and survival prognosis. Compared...
Source: Oncology Reports - Category: Cancer & Oncology Tags: Oncol Rep Source Type: research
Authors: Zhang XH, Yang L, Liu XJ, Zhan Y, Pan YX, Wang XZ, Luo JM Abstract Suppressor of cytokine signaling‑1 (SOCS1) is a widely recognized tumor suppressor gene. Silencing of SOCS1 expression as a result of promoter methylation is associated with occurrence and development of solid tumors such as liver, cervical and pancreatic cancer. However, the association between SOCS1 gene methylation and acute myeloid leukemia (AML) has not been well explored. In the present study, we examined whether gene expression and methylation status of SOCS1 was altered in AML, and whether this was related to disease occurrence an...
Source: Oncology Reports - Category: Cancer & Oncology Tags: Oncol Rep Source Type: research
Once-weekly dulaglutide is effective for glycemic control in patients with type 2 diabetes and moderate to severe kidney disease, while helping to slow renal function decline, new research shows.Reuters Health Information
Source: Medscape Medical News Headlines - Category: Consumer Health News Tags: Medscape Today News Source Type: news
This study is the first to show that downregulation of PAPP-A expression in adult mice can significantly extend life span. Importantly, this beneficial longevity phenotype is distinct from the dwarfism of long-lived PAPP-A KO, Ames dwarf, Snell dwarf and growth hormone receptor (GHR) KO mice with germ-line mutations. Thus, downregulation of PAPP-A expression joins other treatment regimens, such as resveratrol, rapamycin and dietary restriction, which can extend life span when started in mice as adults. In a recent study, inducible knockdown of the GHR in young adult female mice increased maximal, but not median, lif...
Source: Fight Aging! - Category: Research Authors: Tags: Newsletters Source Type: blogs
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