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Total 71 results found since Jan 2013.

Post-Stroke Disability at a National Referral Hospital in Tanzania (P3.322)
Conclusions:In this low-resource setting, individuals with stroke face a severe burden of disability and high risk of mortality. The majority of participants experienced severe deficits following stroke, as assessed through NIHSS and mRS. While this study may be limited by referral bias, the high toll of disability among this population suggests that post-stroke disability places a significant burden on Tanzanian families and society.Study Supported by:This abstract was made possible with help from the Harvard University Center for AIDS Research (CFAR), an NIH funded program (P30 AI060354), subgrant to F. Mateen.Disclosure...
Source: Neurology - April 17, 2017 Category: Neurology Authors: Wibecan, L., Mmbando, T., Grundy, S., Klein, J., Mateen, F., Okengo, K. Tags: Global Health Source Type: research

Antiphospholipid Antibodies and the Risk of Stroke in Urban and Rural Tanzania: A Community-Based Case-Control Study Clinical Sciences
Conclusions— The presence of lupus anticoagulant is a strong, and to date unrecognized, risk factor for stroke in Tanzania, especially in young and middle-aged individuals.
Source: Stroke - September 25, 2016 Category: Neurology Authors: de Mast, Q., Molhoek, J. E., van der Ven, A. J., Gray, W. K., de Groot, P. G., Jusabani, A., Mugusi, F., Urbanus, R. T., Walker, R. W. Tags: Etiology, Mechanisms, Pathophysiology, Cerebrovascular Disease/Stroke, Ischemic Stroke Clinical Sciences Source Type: research

Tanzania: Hypertension Is a Silent Killer All Must Be Aware of
[Citizen] An increasingly high number of young Tanzanian and middle-aged are succumbing to diseases that had traditionally been associated with old age. One such disease is hypertension, the main cause of heart attacks and stroke.
Source: AllAfrica News: Health and Medicine - September 12, 2016 Category: African Health Source Type: news

Complications of sickle cell anaemia in children in Northwestern Tanzania.
Conclusion Children with SCA receiving care in Tanzania are diagnosed late, hospitalized frequently, and have severe complications. Opportunities exist to improve care through wider access to screening and diagnosis as well as better coordination of comprehensive care. PMID: 26868490 [PubMed - as supplied by publisher]
Source: Hematology - February 14, 2016 Category: Hematology Tags: Hematology Source Type: research

Trends in stroke admissions to a Tanzanian hospital over four decades: A retrospective audit
ConclusionsThe burden of stroke on health services in Tanzania appears to have increased rapidly. If this increase is to be slowed then sustainable primary preventative measures to target known stroke risk factors will be required.This article is protected by copyright. All rights reserved.
Source: Tropical Medicine and International Health - May 16, 2015 Category: Tropical Medicine Authors: Richard W. Walker, Rachel Viney, Laura Green, Manasseh Mawanswila, Venance P. Maro, Charlotte Gjertsen, Hannah Godfrey, Rosanna Smailes, William K. Gray Tags: Original Article Source Type: research

Case‐fatality and disability in the Tanzanian Stroke Incidence Project cohort
ConclusionsCase‐fatality rates are higher than reported in high‐income countries, with post‐stroke disability a significant predictor of death. Sustainable interventions to reduce post‐stroke disability in this setting should be investigated.
Source: Acta Neurologica Scandinavica - May 5, 2015 Category: Neurology Authors: R. W. Walker, K. Wakefield, W. K. Gray, A. Jusabani, M. Swai, F. Mugusi Tags: Original Article Source Type: research

Levels of functional disability in elderly people in Tanzania with dementia, stroke and Parkinson's disease.
CONCLUSIONS: Levels of disability from these conditions is high and is likely to increase with demographic ageing. Innovative, community-based strategies to reduce disability levels should be investigated. PMID: 25777617 [PubMed - as supplied by publisher]
Source: Acta Neuropsychiatrica - March 20, 2015 Category: Psychiatry Tags: Acta Neuropsychiatr Source Type: research

Haptoglobin, alpha‐thalassaemia and glucose‐6‐phosphate dehydrogenase polymorphisms and risk of abnormal transcranial Doppler among patients with sickle cell anaemia in Tanzania
Summary Transcranial Doppler ultrasonography measures cerebral blood flow velocity (CBFv) of basal intracranial vessels and is used clinically to detect stroke risk in children with sickle cell anaemia (SCA). Co‐inheritance in SCA of alpha‐thalassaemia and glucose‐6‐phosphate dehydrogenase (G6PD) polymorphisms is reported to associate with high CBFv and/or risk of stroke. The effect of a common functional polymorphism of haptoglobin (HP) is unknown. We investigated the effect of co‐inheritance of these polymorphisms on CBFv in 601 stroke‐free Tanzanian SCA patients aged <24 years. Homozygosity for alpha‐t...
Source: British Journal of Haematology - February 22, 2014 Category: Hematology Authors: Sharon E. Cox, Julie Makani, Deogratias Soka, Veline S. L'Esperence, Edward Kija, Paula Dominguez‐Salas, Charles R. J. Newton, Anthony A. Birch, Andrew M. Prentice, Fenella J. Kirkham Tags: Research Paper Source Type: research

Aphasia and swallowing problems in subjects with incident stroke in rural northern Tanzania: a case-control study.
Conclusions: This is the first attempt to describe aphasia incidence in a sub-Saharan African language. Further work on the psychometric properties of the screening instrument is warranted. Given that it delivers a relatively coarse indication of language disturbance, it is likely that incidence of aphasia in the current cohort is underestimated. PMID: 24521840 [PubMed - in process]
Source: Topics in Stroke Rehabilitation - January 1, 2014 Category: Neurology Authors: Miller N, Gray WK, Howitt SC, Jusabani A, Swai M, Mugusi F, Jones MP, Walker RW Tags: Top Stroke Rehabil Source Type: research

Hypertension-related diseases as a common cause of hospital mortality in Tanzania: a 3-year prospective study
Conclusion: NCDs account for half of all deaths, admissions and hospital days at our Tanzanian hospital and hypertension-related diseases were the most common NCD. Hypertension accounted for 34% of NCD deaths and 15% of all deaths. Hypertension was the second most common cause of death overall and the leading cause of death in patients more than 50 years old. More than half of hypertension-related deaths occurred before retirement age. These findings have important implications for public health and medical education in sub-Saharan Africa, wherein hypertension and related diseases have not traditionally been given a high priority.
Source: Journal of Hypertension - August 16, 2013 Category: Cardiology Tags: ORIGINAL PAPERS: Epidemiology Source Type: research

Electrocardiographic Assessment of Coronary Artery Disease and Stroke Risk Factors in Rural and Urban Tanzania: A Case–control Study
Conclusions: This is the first published study of ECG assessment of CAD and other stroke risk factors in an incident population of stroke cases in sub-Saharan Africa. It suggests that concomitant CAD in black African stroke cases is more common than previously suggested.
Source: Journal of Stroke and Cerebrovascular Diseases - April 1, 2013 Category: Neurology Authors: Richard W. Walker, Matthew Dewhurst, William K. Gray, Ahmed Jusabani, Eric Aris, Nigel Unwin, Mark Swai, Philip C. Adams, Ferdinand Mugusi Tags: Original Articles Source Type: research