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Total 71 results found since Jan 2013.

Antiphospholipid Antibodies and the Risk of Stroke in Urban and Rural Tanzania: A Community-Based Case-Control Study Clinical Sciences
Conclusions— The presence of lupus anticoagulant is a strong, and to date unrecognized, risk factor for stroke in Tanzania, especially in young and middle-aged individuals.
Source: Stroke - September 25, 2016 Category: Neurology Authors: de Mast, Q., Molhoek, J. E., van der Ven, A. J., Gray, W. K., de Groot, P. G., Jusabani, A., Mugusi, F., Urbanus, R. T., Walker, R. W. Tags: Etiology, Mechanisms, Pathophysiology, Cerebrovascular Disease/Stroke, Ischemic Stroke Clinical Sciences Source Type: research

Aphasia and swallowing problems in subjects with incident stroke in rural northern Tanzania: a case-control study.
Conclusions: This is the first attempt to describe aphasia incidence in a sub-Saharan African language. Further work on the psychometric properties of the screening instrument is warranted. Given that it delivers a relatively coarse indication of language disturbance, it is likely that incidence of aphasia in the current cohort is underestimated. PMID: 24521840 [PubMed - in process]
Source: Topics in Stroke Rehabilitation - January 1, 2014 Category: Neurology Authors: Miller N, Gray WK, Howitt SC, Jusabani A, Swai M, Mugusi F, Jones MP, Walker RW Tags: Top Stroke Rehabil Source Type: research

Electrocardiographic Assessment of Coronary Artery Disease and Stroke Risk Factors in Rural and Urban Tanzania: A Case–control Study
Conclusions: This is the first published study of ECG assessment of CAD and other stroke risk factors in an incident population of stroke cases in sub-Saharan Africa. It suggests that concomitant CAD in black African stroke cases is more common than previously suggested.
Source: Journal of Stroke and Cerebrovascular Diseases - April 1, 2013 Category: Neurology Authors: Richard W. Walker, Matthew Dewhurst, William K. Gray, Ahmed Jusabani, Eric Aris, Nigel Unwin, Mark Swai, Philip C. Adams, Ferdinand Mugusi Tags: Original Articles Source Type: research

Efficacy of Fluoxetine for Post-Ischemic Stroke Depression in Tanzania
Post-stroke fluoxetine trials are primarily conducted in high-income countries. We characterize post-ischemic stroke depression in fluoxetine-treated and -untreated study participants in urban Tanzania.
Source: Journal of Stroke and Cerebrovascular Diseases - November 2, 2021 Category: Neurology Authors: Dylan R. Rice, Kigocha Okeng'o, Emmanuel Massawe, Seif Ismail, Notburga A. Mworia, Faraja Chiwanga, Boniface Kapina, Michael Wasserman, Farrah J. Mateen Source Type: research

MEASURING AMBULATION, MOTOR, AND BEHAVIORAL OUTCOMES WITH POST-STROKE FLUOXETINE IN TANZANIA: THE Phase II MAMBO TRIAL
We test the safety of fluoxetine post-ischemic stroke in Sub-Saharan Africa. Adults with acute ischemic stroke, seen
Source: Journal of Stroke and Cerebrovascular Diseases - March 20, 2022 Category: Neurology Authors: Emmanuel Massawe, Notburga A. Mworia, Seif Ismail, Dylan R. Rice, Andre C. Vogel, Boniface Kapina, Novath Mukyanuzi, Deus C. Buma, Jef Gluckstein, Michael Wasserman, Susan E. Fasoli, Faraja Chiwanga, Farrah J. Mateen, Kigocha Okeng'o Source Type: research

Predictors of 30-day mortality among stroke patients admitted at a tertiary teaching hospital in northwestern tanzania: a prospective cohort study
Stroke is the 2nd leading cause of death worldwide, with the highest mortality in Low-middle-income countries particularly in sub-Saharan Africa. We aimed to investigate the predictors of 30-day mortality among stroke patients admitted at a tertiary hospital in Northwestern Tanzania.
Source: Journal of Stroke and Cerebrovascular Diseases - March 30, 2023 Category: Neurology Authors: Sarah Shali Matuja, Gilbert Mlay, Fredrick Kalokola, Patrick Ngoya, Jemima Shindika, Rashid Ali Ahmed, Basil Tumaini, Khuzeima Khanbhai, Reuben Mutta, Mohamed Manji, Faheem Sheriff, Karim Mahawish Source Type: research

Anxiety in Patients With Acute Ischemic Stroke: Risk Factors and Effects on Functional Status
Conclusion: Depressive symptoms are the major correlates of PSA while more severe PSA is associated with poorer ADL and health-related QOL. Acute lesions involving CHWM may correlate with PSA in ischemic stroke patients with mild-to-moderate neurologic deficits, supporting a lesion-location hypothesis in PSA.IntroductionAnxiety is prevalent after stroke and occurs in about one-quarter of stroke survivors (1, 2). Poststroke anxiety (PSA) may have a negative impact on quality of life (QOL) of stroke survivors, affecting their rehabilitation (3). Furthermore, one prospective study found that severe anxiety symptoms were assoc...
Source: Frontiers in Psychiatry - April 16, 2019 Category: Psychiatry Source Type: research

Post-Stroke Disability at a National Referral Hospital in Tanzania (P3.322)
Conclusions:In this low-resource setting, individuals with stroke face a severe burden of disability and high risk of mortality. The majority of participants experienced severe deficits following stroke, as assessed through NIHSS and mRS. While this study may be limited by referral bias, the high toll of disability among this population suggests that post-stroke disability places a significant burden on Tanzanian families and society.Study Supported by:This abstract was made possible with help from the Harvard University Center for AIDS Research (CFAR), an NIH funded program (P30 AI060354), subgrant to F. Mateen.Disclosure...
Source: Neurology - April 17, 2017 Category: Neurology Authors: Wibecan, L., Mmbando, T., Grundy, S., Klein, J., Mateen, F., Okengo, K. Tags: Global Health Source Type: research

Trends of frequency, mortality and risk factors among patients admitted with stroke from 2017 to 2019 to the medical ward at Kilimanjaro Christian Medical Centre hospital: a retrospective observational study
Conclusion The burden of stroke on individuals and health services is increasing over time, which reflects a lack of awareness on the cause of stroke and effective preventive measures. Prioritising interventions directed towards the reduction of non-communicable diseases and associated complications, such as stroke, is urgently needed.
Source: BMJ Open - July 31, 2023 Category: General Medicine Authors: Moshi, B., Yongolo, N., Biswaro, S. M., Maro, H., Linus, S., Siebert, S., Nkenguye, W., McIntosh, E., Shirima, F., Njau, R. E., Andongolile, A. A., Mwanswila, M. J., Halliday, J. E. B., Krauth, S., Kilonzo, K., Walker, R. W., Temu, G. A., Mmbaga, B. T. Tags: Open access, Cardiovascular medicine Source Type: research

Case‐fatality and disability in the Tanzanian Stroke Incidence Project cohort
ConclusionsCase‐fatality rates are higher than reported in high‐income countries, with post‐stroke disability a significant predictor of death. Sustainable interventions to reduce post‐stroke disability in this setting should be investigated.
Source: Acta Neurologica Scandinavica - May 5, 2015 Category: Neurology Authors: R. W. Walker, K. Wakefield, W. K. Gray, A. Jusabani, M. Swai, F. Mugusi Tags: Original Article Source Type: research

Perceptions of Stroke and Associated Health-Care-Seeking Behavior in Northern Tanzania: A Community-Based Study
Conclusions: Knowledge of stroke symptoms and perception of self-risk are low in northern Tanzania, but most residents would present to a hospital for stroke-like symptoms.Neuroepidemiology
Source: Neuroepidemiology - April 15, 2019 Category: Epidemiology Source Type: research

Opportunities for intervention: stroke treatments, disability and mortality in urban Tanzania
ConclusionsThe 90-day mortality of stroke presenting at MNH is 50%, much higher than in higher income settings. Although severe stroke presentations are a major factor, efforts to improve the quality of care and prevent complications of stroke are urgently needed. Acute stroke interventions with low number needed to treat represent challenging long-term goals.
Source: International Journal for Quality in Health Care - August 28, 2018 Category: International Medicine & Public Health Source Type: research

Predictors of 30-day mortality among patients with stroke admitted at a tertiary teaching hospital in Northwestern Tanzania: A prospective cohort study
ConclusionStroke is associated with a high 30-day mortality rate in Northwestern Tanzania. Concerted efforts are warranted in managing patients with stroke, with particular attention to individuals with severe strokes, ECG abnormalities, and swallowing difficulties to reduce early morbidity and mortality.
Source: Frontiers in Neurology - January 18, 2023 Category: Neurology Source Type: research

The characteristics of stroke and its rehabilitation in Northern Tanzania
CONCLUSION: Stroke patients at the KCMC lack access to rehabilitation therapies. Insufficient access to rehabilitation therapies may warrant the need to explore alternative approaches such as tele-rehabilitation technologies in Tanzania.PMID:34340643 | DOI:10.1080/16549716.2021.1927507
Source: Global Health Action - August 3, 2021 Category: International Medicine & Public Health Authors: Egfrid Michael Mkoba Gunnevi Sundelin Klas-G öran Sahlen Ann S örlin Source Type: research