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Total 64 results found since Jan 2013.
Management of carotid artery stenosis
Acta Neurol Taiwan. 2021 Dec 15;30(4):123-127.ABSTRACTThe incidence of both ischemic and hemorrhagic stroke is more common in Asians compared to Caucasian (1). It is found there is a decreased incidence of ischemic stroke in Northern America but increased incidence in Africa, Mongolia and southeast Asia. In the epidemiological study of carotid artery stenosis (CAS), Framingham study showed the prevalence of significant extracranial CAS was 7% in women and 9% in men (2). Among all strokes in Caucasian population, 20 to 30% were due to extracranial CAS and 5 to 10% due to intracranial atherosclerosis (3, 4). Northern Manhatt...
Source: Acta Neurologica Taiwanica - November 29, 2021 Category: Neurology Authors: Tsong-Hai Lee Source Type: research
Eerdun Wurile protects neuron and promotes neurite outgrowth through regulation of apoptotic gene expression in PC-12 cells
Eerdun Wurile (EW) is one of the most widely used traditional Mongolian medicines for stroke recovery. Previous studies revealed that EW regulates brain gene expression in a rat model of middle cerebral artery occlusion (MCAO). However, the fraction of active components and the specific genes regulated by such fractions have not been elucidated clearly. The study shows that the extracts of E...
Source: Journal of Medicinal Plants Research - September 10, 2020 Category: Complementary Medicine Source Type: research
Enhancement of de novo sequencing, assembly and annotation of the Mongolian gerbil genome with transcriptome sequencing and assembly from several different tissues
The Mongolian gerbil (Meriones unguiculatus) has historically been used as a model organism for the auditory and visual systems, stroke/ischemia, epilepsy and aging related research since 1935 when laboratory ger...
Source: BMC Genomics - November 27, 2019 Category: Genetics & Stem Cells Authors: Shifeng Cheng, Yuan Fu, Yaolei Zhang, Wenfei Xian, Hongli Wang, Benedikt Grothe, Xin Liu, Xun Xu, Achim Klug and Elizabeth A. McCullagh Tags: Research article Source Type: research
Chungkookjang, a soy food, fermented with Bacillus amyloliquefaciens protects gerbils against ishcmeic stroke injury, and post-stroke hyperglycemia
In conclusion, the daily intake of chungkookjang fermented with B. amyloliquefaciens improved the gut microbiome, increased blood flow to the brain, suppressed systemic inflammation, and may reduce the susceptibility to injury from ischemic stroke in gerbils subjected to ischemic injury.Graphical abstract
Source: Food Research International - October 31, 2019 Category: Food Science Source Type: research
Bioactive components of ethnomedicine Eerdun Wurile regulate the transcription of pro-inflammatory cytokines in microglia
ConclusionCollectively our data suggest that the bioactive chemical pool which is responsible for the therapeutic effects of EW can be extracted in petroleum ether, and fractionated to a relatively small multiple components. Such components include known anti-inflammatory chemicals, which may contribute to the possible microglia polarization in brain lesion during the recovery of ischemic stroke.Graphical abstract
Source: Journal of Ethnopharmacology - September 15, 2019 Category: Drugs & Pharmacology Source Type: research
Preventive Effects of Dexmedetomidine on Renal Dysfunction and Hemodynamic Stability in Malignant Obstructive Jaundice Patients During Peri-Operative Period.
CONCLUSIONS Dexmedetomidine plays preventive effects on renal dysfunction and hemodynamic stability in malignant obstructive jaundice patients during peri-operative period.
PMID: 31498783 [PubMed - in process]
Source: Medical Science Monitor - September 11, 2019 Category: Research Tags: Med Sci Monit Source Type: research
Investigation of the protective effect of heparin pre-treatment on cerebral ischaemia in gerbils.
The objective of this study was to investigate the mechanism underlying the effects of heparin pre-treatment on cerebral injury in the gerbil. Materials and methods: A total of 80 healthy Mongolian gerbils were randomly divided into four groups to establish cerebral ischaemia model by bilateral carotid artery occlusion: control (no anaesthesia and surgery), sham (no occlusion), non-anticoagulation (occlusion), and anti-coagulation treatment groups (50 IU/100 g heparin pre-treated, occlusion). Gerbils were anesthetized with 40 mg/kg pentobarbital sodium through intraperitoneal injection before operation except for the...
Source: Pharmaceutical Biology - August 15, 2019 Category: Drugs & Pharmacology Tags: Pharm Biol Source Type: research
Combined Effects of A Body Shape Index and Serum C-reactive Protein on Ischemic Stroke Incidence among Mongolians in China
ConclusionWe found that participants with simultaneously high ABSI and high CRP levels had the highest risk of ischemic stroke in the Mongolian population. Our findings suggest that the combination of high ABSI and high CRP levels may increase the risk of ischemic stroke.
Source: Biomedical and Environmental Sciences - July 4, 2019 Category: Biomedical Science Source Type: research
Combined Effects of A Body Shape Index and Serum C-reactive Protein on Ischemic Stroke Incidence among Mongolians in China.
CONCLUSION: We found that participants with simultaneously high ABSI and high CRP levels had the highest risk of ischemic stroke in the Mongolian population. Our findings suggest that the combination of high ABSI and high CRP levels may increase the risk of ischemic stroke.
PMID: 30987691 [PubMed - in process]
Source: Biomedical and Environmental Sciences : BES - February 28, 2019 Category: Biomedical Science Authors: Wang GL, Zhang R, Zhou YT, Wang AL, Xu T, Zhang MZ, Li HM, Zhang YH Tags: Biomed Environ Sci Source Type: research
Scientists Identify the First-Known Offspring of Two Different Groups of Early Humans, Study Says
(BERLIN) — Scientists say they’ve found the remains of a prehistoric female whose mother was a Neanderthal and whose father belonged to another extinct group of human relatives known as Denisovans.
The 90,000-year-old bone fragment found in southern Siberia marks the first time a direct offspring of these two groups has been discovered, according to a study published Wednesday in the journal Nature.
Both groups disappeared by about 40,000 years ago. Neanderthals lived in Europe and Asia, while fossils of Denisovans are known only from the cave where the fragment was found.
Past genetic studies have shown interb...
Source: TIME: Science - August 23, 2018 Category: Science Authors: FRANK JORDANS / AP Tags: Uncategorized onetime overnight Research Source Type: news
Traditional Mongolian medicine Eerdun Wurile improves stroke recovery through regulation of gene expression in rat brain
Conclusion Our data collectively indicated that EW enhances expression of growth factors including Igf1 and Igf2 in neurons and microglia, and may stimulate microglia polarization in the brain. The consequences of such activity include stimulation of neuron growth, hydrolysis and clearance of cell debris at the lesion, as well as the angiogenesis. Graphical abstract
Source: Journal of Ethnopharmacology - May 26, 2018 Category: Drugs & Pharmacology Source Type: research
