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Total 64 results found since Jan 2013.

Combined effects of family history of CVD and heart rate on ischemic stroke incidence among Inner Mongolians in China.
This study aimed to evaluate the combined effects of family history of cardiovascular diseases (FHCVD) and heart rate on ischemic stroke incidence among Inner Mongolians in China. METHODS: A prospective cohort study was conducted among 2589 participants aged 20 years and older from Inner Mongolia, China. The participants were divided into four groups according to status of FHCVD and heart rate and followed up from June 2002 to July 2012. Cox proportional hazards models were used to evaluate the combined effects of FHCVD and heart rate on the incidence of ischemic stroke. RESULTS: A total of 76 ischemic stroke occu...
Source: Neurological Research - April 22, 2016 Category: Neurology Tags: Neurol Res Source Type: research

Lipid Accumulation Product and Hypertension Related to Stroke: a 9.2-Year Prospective Study Among Mongolians in China.
CONCLUSIONS: The present study showed that high LAP was associated with an increased risk of future stroke, and hypertensives with high LAP had the highest risk of stroke among Inner Mongolians. These findings indicate that LAP and hypertension may be valuable to predict and prevent stroke incidence. PMID: 26797267 [PubMed - as supplied by publisher]
Source: Journal of Atherosclerosis and Thrombosis - January 24, 2016 Category: Cardiology Tags: J Atheroscler Thromb Source Type: research

Combined effects of hypertension and heart rate on the risk of stroke and coronary heart disease: a population-based prospective cohort study among Inner Mongolians in China
n & Yonghong Zhang
Source: Hypertension Research - December 7, 2015 Category: Cardiology Authors: Chongke ZhongXiaoyan ZhongTian XuHao PengHongmei LiMingzhi ZhangAili WangTan XuYingxian SunYonghong Zhang Tags: cohort study coronary heart disease heart rate stroke Source Type: research

Assessment of dose-effect and therapeutic time window in preclinical studies of rhEGF and GHRP-6 coadministration for stroke therapy.
Authors: Subirós N, Pérez-Saad HM, Berlanga JA, Aldana L, García-Illera G, Gibson CL, García-Del-Barco D Abstract BACKGROUND: Stroke continues to be a leading cause of mortality and morbidity worldwide, and novel therapeutic options for ischaemic stroke are urgently needed. In this context, drug combination therapies seem to be a viable approach, which has not been fully explored in preclinical studies. OBJECTIVES: In this work, we assessed the dose-response relationship and therapeutic time window, in global brain ischaemia, of a combined therapeutic approach of recombinant human epidermal growth factor (E...
Source: Neurological Research - August 29, 2015 Category: Neurology Tags: Neurol Res Source Type: research

Hypertension subtypes and risk of cardiovascular diseases in a Mongolian population, inner Mongolia, China.
CONCLUSIONS: IDH and SDH were significantly associated with the increased risk of cardiovascular diseases; this study suggests that carefully monitoring and actively treating the subjects with IDH should be an important strategy for CVD prevention among Mongolian population. PMID: 26268426 [PubMed - as supplied by publisher]
Source: Clinical and Experimental Hypertension - August 13, 2015 Category: Cardiology Authors: Li H, Kong F, Xu J, Zhang M, Wang A, Zhang Y Tags: Clin Exp Hypertens Source Type: research

Behavioral effects and neural changes induced by continuous and not continuous treadmill training, post bilateral cerebral ischemia in gerbils.
This study aims to investigate the effects of treadmill training and the possible influences of the start, regularity, and duration after experimental ischemic stroke. We performed bilateral occlusion of the both carotid arteries for five minutes in Mongolian gerbils. The training groups were: continuous training for five consecutive days or not continuous training for three non-consecutive days. The groups remained in the treadmill for 15minutes, and the training started 12 or 24hours after the stroke. In the activity cage (AC), was registered the behaviors of crossing and distance traveled. The forced motor behavior was ...
Source: Behavioural Brain Research - May 11, 2015 Category: Neurology Authors: Kitabatake TT, Marini LC, Gonçalves RB, Bertolino G, Souza HC, Araujo JE Tags: Behav Brain Res Source Type: research

The interactive effect of diabetes and central obesity on stroke: a prospective cohort study of inner Mongolians
Conclusions: The participants who were both diabetic and centrally obese had significantly higher risk for incident stroke than the combination of individuals who individually had either condition among Mongolian population. This study suggests that central obesity and diabetes act synergistically to increase the risk of stroke.
Source: BMC Neurology - April 28, 2015 Category: Neurology Authors: Jennifer OlofindayoHao PengYan LiuHongmei LiMingzhi ZhangAili WangYonghong Zhang Source Type: research

Effect of arginine vasopressin on the cortex edema in the ischemic stroke of mongolian gerbils
• Ischemic stroke increased arginine vasopressin (AVP) levels in the cortex and decreased the cortex specific gravities (edema).• There were many negative relationships between the cortex edema and AVP concentration.• Intranasal AVP aggravated the focal cortex edema, but intranasal AVP receptor antagonist mitigated that edema.• There were not changes of the cortex edema and AVP concentration in the non-ischemic cortex.• AVP participated in the process of ischemia-evoked cortex edema.
Source: Neuropeptides - March 24, 2015 Category: Neuroscience Authors: Xue-Yan Zhao, Chun-Fang Wu, Jun Yang, Yang Gao, Zhi-Xiu Song, Fang-Jie Sun, Le-Le Bao, Da-Xin Wang, Chang-Hong Wang, Bao-Cheng Lin Source Type: research

Blood pressure components and stroke in Inner Mongolians — A prospective cohort study
Stroke is the leading cause of disability and the second-leading cause of death in the world [1]. It is becoming an ever-increasing public health burden in China [2]. There is a strong association between both systolic blood pressure (SBP) and diastolic blood pressure (DBP) and stroke, but even in cases of normal BP stroke can still occur [3]. This indicates that other risk factors and BP components other than SBP or DBP may play a role in the development of stroke. In addition to SBP and DBP, BP is also characterized by pulse pressure (PP) and mean arterial pressure (MAP).
Source: International Journal of Cardiology - August 2, 2014 Category: Cardiology Authors: Hao Peng, Anna Tan, Shuhai Han, Zhong Ju, Aili Wang, Yonghong Zhang Tags: Letter to the Editor Source Type: research

Blood Pressure Components and Stroke in Inner Mongolians - A Prospective Cohort Study
Introduction. Stroke is the leading cause of disability and the second-leading cause of death in the world [1]. It is becoming an ever-increasing public health burden in China [2]. There is a strong association between both systolic blood pressure (SBP) and diastolic blood pressure (DBP) and stroke, but even in cases of normal BP stroke can still occur [3]. This indicates that other risk factors and BP components other than SBP or DBP may play a role in the development of stroke. In addition to SBP and DBP, BP is also characterized by pulse pressure (PP) and mean arterial pressure (MAP).
Source: International Journal of Cardiology - August 2, 2014 Category: Cardiology Authors: Hao Peng, Anna Tan, Shuhai Han, Zhong Ju, Aili Wang, Yonghong Zhang Source Type: research

Hypertension and elevated C-reactive protein: Future risk of ischemic stroke in a prospective cohort study among inner Mongolians in China
Hypertension and C-reactive protein (CRP) have been investigated extensively in regard to risk of stroke and cardiovascular disease in population. However, few studies have paid an attention to the cumulative effect of hypertension and CRP on the development of ischemic stroke, and there are no published studies regarding cumulative effect of hypertension and CRP on the ischemic stroke incidence in an Inner Mongolian population. The purpose of present study is to assess the association between hypertension, CRP and the future risk of ischemic stroke, and the potential role of CRP to enhance risk prediction of ischemic stro...
Source: International Journal of Cardiology - April 24, 2014 Category: Cardiology Authors: Aili Wang, Tan Xu, Tian Xu, Mingzhi Zhang, Hongmei Li, Weijun Tong, Yonghong Zhang Tags: Letters to the Editor Source Type: research