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Condition: Blindness

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Total 481 results found since Jan 2013.

Short communication: unique metabolic signature of proliferative retinopathy in the tear fluid of diabetic patients with comorbidities — preliminary data for PPPM validation
AbstractType 2 diabetes (T2DM) defined as the adult-onset type that is primarily not insulin-dependent, comprises over 95% of all diabetes mellitus (DM) cases. According to global records, 537 million adults aged 20-79 years are affected by DM that means at least 1 out of 15 persons. This number is projected to grow by 51% by the year 2045. One of the most common complications of T2DM is diabetic retinopathy (DR) with an overall prevalence over 30%. The total number of the DR-related visual impairments is on the rise, due to the growing T2DM population. Proliferative diabetic retinopathy (PDR) is the progressing DR and lea...
Source: EPMA Journal - February 22, 2023 Category: International Medicine & Public Health Source Type: research

Diabetic retinopathy as the leading cause of blindness and early predictor of cascading complications —risks and mitigation
AbstractProliferative diabetic retinopathy (PDR) the sequel of diabetic retinopathy (DR), a frequent complication of diabetes mellitus (DM), is the leading cause of blindness in the working-age population. The current screening process for the DR risk is not sufficiently effective such that often the disease is undetected until irreversible damage occurs. Diabetes-associated small vessel disease and neuroretinal changes create a vicious cycle resulting in the conversion of DR into PDR with characteristic ocular attributes including excessive mitochondrial and retinal cell damage, chronic inflammation, neovascularisation, a...
Source: EPMA Journal - February 13, 2023 Category: International Medicine & Public Health Source Type: research

Molecules, Vol. 28, Pages 126: In Vitro Evaluation of & alpha;-amylase and & alpha;-glucosidase Inhibition of 2,3-Epoxyprocyanidin C1 and Other Constituents from Pterocarpus erinaceus Poir
Molecules, Vol. 28, Pages 126: In Vitro Evaluation of α-amylase and α-glucosidase Inhibition of 2,3-Epoxyprocyanidin C1 and Other Constituents from Pterocarpus erinaceus Poir Molecules doi: 10.3390/molecules28010126 Authors: Romeo Toko Feunaing Alfred Ngenge Tamfu Abel Joel Yaya Gbaweng Larissa Mekontso Magnibou Fidele Ntchapda Celine Henoumont Sophie Laurent Emmanuel Talla Rodica Mihaela Dinica Diabetes mellitus is a metabolic disorder which is one of the leading causes of mortality and morbidities in elderly humans. Chronic diabetes can lead to kidney failure, blindness, limb a...
Source: Molecules - December 23, 2022 Category: Chemistry Authors: Romeo Toko Feunaing Alfred Ngenge Tamfu Abel Joel Yaya Gbaweng Larissa Mekontso Magnibou Fidele Ntchapda Celine Henoumont Sophie Laurent Emmanuel Talla Rodica Mihaela Dinica Tags: Article Source Type: research

Helping defeat diabetes in Arizona
Today, 1 in 10 Arizonans — about 786,000 people — have diabetes, a disease that impacts the way the body turns food into energy. People living with diabetes are also more than twice as likely to have a stroke and more prone to suffering from depression. Nationally, it is the eighth leading cause of death, and the number -one cause of kidney failure, foot and lower leg amputation, and blindness in adults.* At Blue Cross Blue Shield of Arizona (BCBSAZ), it’s our mission to inspire health and…
Source: bizjournals.com Health Care:Pharmaceuticals headlines - December 1, 2022 Category: Pharmaceuticals Authors: Blue Cross Blue Shield of Arizona Source Type: news

EE675 Cost-Utility Analysis of Metabolic Surgery Compared With Best Medical Care for the Treatment of Comorbid Type 2 Diabetes and Obesity
Type 2 diabetes (T2D) is associated with an increased risk of many serious health complications including stroke, kidney disease and blindness. Weight-loss is an important part of T2D management and can lead to improvements in cardiometabolic risk factors and an associated decreased risk of T2D-related complications. The aim of this cost-utility analysis was to estimate the cost-effectiveness of metabolic surgery compared with best medical care (BMC) for the treatment of comorbid T2D and obesity.
Source: Value in Health - December 1, 2022 Category: International Medicine & Public Health Authors: K Jordan, C Teljeur, B Clyne, P Harrington, M Ryan Source Type: research

Costs of major complications in people with and without diabetes in Tasmania, Australia
ConclusionsDiabetes complications are costly, and the costs are higher in people with diabetes than without diabetes. Our results can be used to populate diabetes simulation models and will support policy analyses to reduce the burden of diabetes.PMID:36375176 | DOI:10.1071/AH22180
Source: Australian Health Review - November 14, 2022 Category: Hospital Management Authors: Ngan T T Dinh Barbara de Graaff Julie A Campbell Matthew D Jose Burgess John Timothy Saunder Alex Kitsos Nadine Wiggins Andrew J Palmer Source Type: research

Manual Acupuncture or Combination of Rehabilitation Therapy to Treat Poststroke Dysphagia: A Systematic Review and Meta-Analysis of Randomized Controlled Trials
Conclusion. This meta-analysis provided positive pieces of evidences that acupuncture and acupuncture combined with rehabilitation were better than using rehabilitation alone in the treatment of poststroke dysphagia.PMID:36285156 | PMC:PMC9588332 | DOI:10.1155/2022/8803507
Source: Evidence-based Complementary and Alternative Medicine - October 26, 2022 Category: Complementary Medicine Authors: Hailun Jiang Qiang Zhang Qi Zhao Hao Chen Xi Nan Miao Liu Chunsheng Yin Wei Liu Xiaonong Fan Zhihong Meng Yuzheng Du Source Type: research

Contrast-induced encephalopathy following endovascular treatment for intracranial aneurysms —risk factors analysis and clinical strategy
ConclusionHistory of stroke and posterior circulation aneurysms were main risk factors for CIE. A higher dosage of contrast agents might induce CIE, and the history of hypertension should be considered as well.
Source: Neuroradiology - October 26, 2022 Category: Radiology Source Type: research

Dizziness, Falls, and Hearing Loss in Adults Living With Sickle Cell Disease
DISCUSSION: These results provide justification for patient and health care provider education regarding appropriate referrals for vestibular/balance assessments and provision of fall prevention strategies. Future studies on balance and SCD are encouraged.PMID:36251873 | DOI:10.1044/2022_AJA-22-00059
Source: American Journal of Audiology - October 17, 2022 Category: Audiology Authors: M Dawn Nelson Danielle M Bennett Mark E Lehman Angela I Okonji Source Type: research