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Retinal and Ophthalmic Artery Studies in Ischemic Stroke Patients Using Fundus Photography and Transcranial Doppler Methods (P4.252)
Conclusions:Our study in a robust sample of non-severe stroke patients showed that abnormal retinal AVR is strongly associated with IS patients even after accounting for traditional risk factors. OA-TCD studies, on the other hand, did not have significant associations with stroke group.Disclosure: Dr. Patil has nothing to disclose. Dr. Narayan has nothing to disclose. Dr. Babu K has nothing to disclose.
Source: Neurology - April 17, 2017 Category: Neurology Authors: Patil, K., Narayan, S., Babu, K. R. Tags: Acute and Diagnostic Imaging in Ischemic Stroke and TIA Source Type: research

Stroke Dysbiosis Index (SDI) in Gut Microbiome Are Associated With Brain Injury and Prognosis of Stroke
Conclusions: We developed an index to measure gut microbiota dysbiosis in stroke patients; this index was significantly correlated with patients' outcome and was causally related to outcome in a mouse model of stroke. Our model facilitates the potential clinical application of gut microbiota data in stroke and adds quantitative evidence linking the gut microbiota to stroke. Introduction Ischemic stroke imposes a heavy burden on society, with 24.9 million cases worldwide (1). Although intravenous thrombolysis and endovascular treatment greatly improve some patients' prognosis, the prognosis for most pa...
Source: Frontiers in Neurology - April 23, 2019 Category: Neurology Source Type: research

Early Clinical Signs, Lesion Localization, and Prognostic Factors in Unilateral Symptomatic Internal Carotid Artery Occlusion
Conclusions: In unilateral symptomatic intracranial carotid artery occlusion, poor prognosis and high mortality–associated territorial stroke pattern is frequently observed. Besides, presence of severe stenosis or occlusion and absence of collateral circulation in MCA are associated with poor prognosis.
Source: Journal of Stroke and Cerebrovascular Diseases - April 18, 2014 Category: Neurology Authors: Sibel Güler, Ufuk Utku, Özer Aynaci Tags: Original Articles Source Type: research

Characteristics of Symptomatic Basilar Artery Stenosis Using High-Resolution Magnetic Resonance Imaging in Ischemic Stroke Patients.
CONCLUSIONS: The etiology of stenosis or occlusion was unclear until the development of HR-MRI. With HR-MRI, stroke etiology is better understood, and factors affecting each etiology can be identified. Further studies that clarify the etiology of posterior circulation stroke are required. PMID: 33191363 [PubMed - as supplied by publisher]
Source: Journal of Atherosclerosis and Thrombosis - November 17, 2020 Category: Cardiology Tags: J Atheroscler Thromb Source Type: research

Geographic and Sex Difference in the Distribution of Intracranial Atherosclerosis in China Clinical Sciences
Conclusions— There exists geographic and sex difference in the distribution of symptomatic ICAS in China. Public health measures should strengthen improving social determinants of health and risk factor prevention/control in high-risk populations for decreasing stroke risk.
Source: Stroke - July 22, 2013 Category: Neurology Authors: Pu, Y., Liu, L., Wang, Y., Zou, X., Pan, Y., Soo, Y., Leung, T., Zhao, X., Wong, K. S., Wang, Y., on behalf of the Chinese IntraCranial AtheroSclerosis (CICAS) Study Group Tags: Risk Factors, Acute Cerebral Infarction Clinical Sciences Source Type: research

An Unusual Cause Of Recurrent Ischemic Stroke: Trousseau's Syndrome From Gastric Cancer (P4.231)
CONCLUSIONS: Trousseau’s Syndrome must be considered in those presenting with recurrent strokes with an otherwise negative embolic work up especially in the elderly and those with cancer risk factors. It must prompt the clinician to look for an associated malignancy.Disclosure: Dr. JADEJA has nothing to disclose. Dr. Johnson has nothing to disclose. Dr. Soetanto has nothing to disclose. Dr. Nalleballe has nothing to disclose. Dr. DeNiro has nothing to disclose. Dr. Qureshi has nothing to disclose. Dr. Graber has received personal compensation for activities with Stemedica Inc., Novocure Inc., and Biogen Idec.
Source: Neurology - April 8, 2015 Category: Neurology Authors: Jadeja, N., Johnson, J., Soetanto, A., Nalleballe, K., DeNiro, L., Qureshi, I., Graber, J. Tags: Neuro-oncology: Paraneoplastic Disorders Source Type: research

Posterior hippocampal stroke presenting with transient global amnesia.
We describe a patient with presenting symptoms of TGA, but affected by an ischemic hippocampal stroke. The computed tomography angiography helped the etiologic diagnosis showing an hemodynamic stenosis of the posterior P2P segment. Interestingly, neuropsychological features were consistent with those found in patients suffering TGA. PMID: 28004602 [PubMed - as supplied by publisher]
Source: Neurocase - December 21, 2016 Category: Neurology Authors: Naldi F, Baiardi S, Guarino M, Spinardi L, Cirignotta F, Stracciari A Tags: Neurocase Source Type: research

Sudden bilateral anterior cerebral infarction: unusual stroke associated with unusual vascular anomalies
We describe a 38-year-old male smoker and heavy alcohol user, who awoke with sudden onset of weakness of both lower limbs, and bladder and bowel incontinence. He had consumed excessive amounts of alcohol the previous night. There was no significant past medical history including other vascular risk factors and cardiovascular disease. On admission, he was mute and abulic. The frontal release signs including the forced grasping and the snout reflex were present. Routine full blood count and biochemical analysis were normal. MRI of the brain showed bilateral, nearly symmetrical ACA infarction (figure 1A–C). Time-of-flig...
Source: Postgraduate Medical Journal - January 21, 2013 Category: Journals (General) Authors: Krishnan, M., Kumar, S., Ali, S., Iyer, R. S. Tags: Urology, Open access, Drugs: cardiovascular system, Echocardiography, Stroke, Venous thromboembolism, Radiology, Physiotherapy, Sports and exercise medicine, Clinical diagnostic tests, Radiology (diagnostics) Images in medicine Source Type: research

Delayed bilateral massive stroke following a road traffic accident
A 72-year-old man was found unresponsive. Initial assessment revealed a Glasgow Coma Score of 4 (E1, V1, M2) with equal and reactive small pupils. The patient's past medical history included alcohol excess, osteoarthritis and a transient ischaemic attack. Of note the patient was involved in a high speed road traffic accident 3 days prior, suffering only seemingly minor injuries. The patient underwent CT scanning which revealed extensive bilateral frontoparietal lobe infarctions (figure 1). CT angiography demonstrated a small calibre internal carotid artery (ICA) on the right, together with complete occlusion of the le...
Source: Emergency Medicine Journal - August 14, 2014 Category: Emergency Medicine Authors: Coulter, I. C., Korsen, H. Tags: Drugs: cardiovascular system, Coma and raised intracranial pressure, Stroke, Radiology, Osteoarthritis, Clinical diagnostic tests, Radiology (diagnostics), Ethics Images in emergency medicine Source Type: research

Internal Carotid Artery Occlusion Causing Acute Cranial Neuropathies
A 54-year-old male with a history of left posterior parietal ischemic stroke, epilepsy, tobacco and marijuana smoking, and alcohol abuse, presented with acute left visual loss and diplopia. On examination, he had reduced left visual acuity and a left oculomotor nerve palsy. CT angiogram from aortic arch to circle of Willis identified extensive thrombus occluding the left common and internal carotid arteries, extending to the left ophthalmic artery. This case demonstrates acute visual loss from ophthalmic artery occlusion, and left oculomotor nerve palsy from occlusion of the inferolateral trunk of the internal carotid arte...
Source: Journal of Stroke and Cerebrovascular Diseases - January 9, 2019 Category: Neurology Authors: Stephen R. Duma, Samer Ghattas, Florence C.F. Chang Tags: Case Report Source Type: research

Mediterranean-style diet and intracranial large artery stenosis in the Northern Manhattan Study
CONCLUSION: In this stroke-free subsample, we did not find a significant association between MeDi and ICAS. We may have been limited by statistical power.PMID:37634256 | DOI:10.1016/j.jstrokecerebrovasdis.2023.107252
Source: Atherosclerosis - August 27, 2023 Category: Cardiology Authors: Dixon Yang Hannah Gardener Farid Khasiyev Tatjana Rundek Clinton B Wright Mitchell Sv Elkind Jose Gutierrez Source Type: research

Pure Thalamic Infarct: 8-Year Follow-Up Study in a Hospital in China
In conclusion, our cohort of pure thalamic infarcts were mainly due to SVO (TOAST), with hypertension as the main risk factor, and the inferolateral artery as the most implicated arterial territory. Less severe outcome or stroke recurrence are identified in long-term follow-up of pure thalamic infarcts. Other comorbidities would be cause of death in aged patients.
Source: Frontiers in Neurology - September 14, 2021 Category: Neurology Source Type: research

Recognition and evaluation of nontraumatic subarachnoid hemorrhage and ruptured cerebral aneurysm.
Abstract Swift diagnosis and treatment are critical for good outcomes in patients with nontraumatic subarachnoid hemorrhage, which is usually caused by a ruptured aneurysm. This type of stroke often results in death or disability. Rates of misdiagnosis and treatment delays for subarachnoid hemorrhage have improved over the years, but these are still common occurrences. Subarachnoid hemorrhage can be more easily diagnosed in patients who present with severe symptoms, unconsciousness, or with thunderclap headache, which is often accompanied by vomiting. The diagnosis is more elusive in patients who present in good c...
Source: American Family Physician - October 1, 2013 Category: Primary Care Authors: Cohen-Gadol AA, Bohnstedt BN Tags: Am Fam Physician Source Type: research

E-006 Familial Incidence of the Congenital Torcular Dural Arteriovenous Shunt
Purpose There are several hereditary disorders that are well known to be associated with arteriovenous malformations (AVMs) involving the central nervous system including Sturge-Weber, Klippel-Trenaunay-Weber, and Parkes-Weber syndromes as well as hereditary haemorrhagic telangiectasia and hereditary neurocutaneous angiomatosis. Furthermore, familial incidence of AVMs in the absence of congenital hereditary disorders also has been reported. Herein, we describe the occurrence of the giant torcular herophili (TH) dural arteriovenous fistula (AVF) in two pediatric cousins treated with endovascular embolization. Case report C...
Source: Journal of NeuroInterventional Surgery - July 26, 2014 Category: Neurosurgery Authors: Honarmand, A., Hurley, M., Daruwalla, V., Ansari, S., Shaibani, A. Tags: Electronic poster abstracts Source Type: research

Man-in-the-barrel syndrome with Delayed Diffusion-weighted MRI Findings (P3.072)
Conclusions:DWI has a high degree of sensitivity and specificity. Nevertheless, false negative results often occur because of small infarct size, early imaging, and brainstem locations. The rate of false negative results with DWI has been estimated to be 17%. We argue it may be advisable to repeat MRI in certain cases were stroke is highly suspected up to 72 hours post symptoms. Often false negative DWI occur in posterior circulation strokes making our case unique, given it is in the anterior circulation. One possible explanation for this, is differences in cerebral reserve between a young patient versus an older patient d...
Source: Neurology - April 17, 2017 Category: Neurology Authors: Magun, R., Ching, M., Sawyer, R., Mowla, A. Tags: Cerebrovascular Disease and Interventional Neurology ePoster Session Source Type: research

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