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Total 8464 results found since Jan 2013.

Arterial Tortuosity: An Imaging Biomarker of Childhood Stroke Pathogenesis? Clinical Sciences
Conclusions— In children with dissection and transient cerebral arteriopathy, cerebral arteries demonstrate increased tortuosity. Quantified arterial tortuosity may represent a clinically relevant imaging biomarker of vascular biology in pediatric stroke.
Source: Stroke - April 24, 2016 Category: Neurology Authors: Wei, F., Diedrich, K. T., Fullerton, H. J., deVeber, G., Wintermark, M., Hodge, J., Kirton, A., the Vascular Effects of Infection in Pediatric Stroke (VIPS) Investigators, Dowling, Benedict, Bernard, Fox, Friedman, Lo, Ichord, Tan, Mackay, Hernandez, Hump Tags: Risk Factors, Angiography, Magnetic Resonance Imaging (MRI), Ischemic Stroke, Vascular Disease Clinical Sciences Source Type: research

Effect of Collateral Blood Flow on Patients Undergoing Endovascular Therapy for Acute Ischemic Stroke Clinical Sciences
Conclusions— Collaterals correlate with baseline National Institutes of Health Stroke Scale, perfusion-weighted imaging volume, and good reperfusion. However, target mismatch patients who reperfuse seem to have favorable outcomes at a similar rate, irrespective of the collateral score. Clinical Trial Registration— URL: http://www.clinicaltrials.gov. Unique identifier: NCT01349946.
Source: Stroke - March 24, 2014 Category: Neurology Authors: Marks, M. P., Lansberg, M. G., Mlynash, M., Olivot, J.-M., Straka, M., Kemp, S., McTaggart, R., Inoue, M., Zaharchuk, G., Bammer, R., Albers, G. W., for Diffusion and Perfusion Imaging Evaluation for Understanding Stroke Evolution 2 (DEFUSE 2) Investigato Tags: Acute Cerebral Infarction, Emergency treatment of Stroke, Angiography, Computerized tomography and Magnetic Resonance Imaging Clinical Sciences Source Type: research

Differential Effect of Baseline Computed Tomographic Angiography Collaterals on Clinical Outcome in Patients Enrolled in the Interventional Management of Stroke III Trial Clinical Sciences
Conclusion— Using data from a large randomized controlled trial (IMS III), we show that baseline computed tomographic angiography collaterals are a robust determinant of final clinical outcome and could be used to select patients for endovascular therapy. Clinical Trial Registration— URL: http://www.clinicaltrials.gov/ct2/show/. Unique identifier: 0020NCT00359424.
Source: Stroke - April 27, 2015 Category: Neurology Authors: Menon, B. K., Qazi, E., Nambiar, V., Foster, L. D., Yeatts, S. D., Liebeskind, D., Jovin, T. G., Goyal, M., Hill, M. D., Tomsick, T. A., Broderick, J. P., Demchuk, A. M., for the Interventional Management of Stroke III Investigators Tags: Acute Cerebral Infarction, Emergency treatment of Stroke, Computerized tomography and Magnetic Resonance Imaging Clinical Sciences Source Type: research

Twelve-Month Clinical and Quality-of-Life Outcomes in the Interventional Management of Stroke III Trial Clinical Sciences
Conclusions— Endovascular therapy improves functional outcome and health-related quality-of-life at 12 months after severe ischemic stroke. Clinical Trial Registration— URL: http://www.clinicaltrials.gov. Unique identifier: NCT00359424.
Source: Stroke - April 27, 2015 Category: Neurology Authors: Palesch, Y. Y., Yeatts, S. D., Tomsick, T. A., Foster, L. D., Demchuk, A. M., Khatri, P., Hill, M. D., Jauch, E. C., Jovin, T. G., Yan, B., von Kummer, R., Molina, C. A., Goyal, M., Schonewille, W. J., Mazighi, M., Engelter, S. T., Anderson, C., Spilker, Tags: Acute Cerebral Infarction, Emergency treatment of Stroke, Angiography, Thrombolysis Clinical Sciences Source Type: research

Feasibility and Diagnostic Value of Cardiovascular Magnetic Resonance Imaging After Acute Ischemic Stroke of Undetermined Origin Clinical Sciences
Conclusions—Our study demonstrated that cvMRI was feasible in the vast majority of included patients with acute ischemic stroke. The diagnostic information of cvMRI seems to be complementary to TEE but is not replacing echocardiography after acute ischemic stroke.Clinical Trial Registration—URL: http://www.clinicaltrials.gov. Unique identifier: NCT01917955.
Source: Stroke - April 24, 2017 Category: Neurology Authors: Karl Georg Haeusler, Christian Wollboldt, Laura zu Bentheim, Juliane Herm, Sebastian Jager, Claudia Kunze, Holger–Carsten Eberle, Claudia Christina Deluigi, Oliver Bruder, Carolin Malsch, Peter U. Heuschmann, Matthias Endres, Heinrich J. Audebert, A Tags: Secondary Prevention, Echocardiography, Magnetic Resonance Imaging (MRI), Ischemic Stroke Original Contributions Source Type: research

One-Year Outcomes After Minor Stroke or High-Risk Transient Ischemic Attack Clinical Sciences
Conclusions—Contemporary secondary stroke prevention strategies based on thorough diagnostic evaluation may contribute to the low subsequent vascular event rates observed in real-world clinical practice in Korea.
Source: Stroke - October 23, 2017 Category: Neurology Authors: Hong-Kyun Park, Beom Joon Kim, Moon-Ku Han, Jong-Moo Park, Kyusik Kang, Soo Joo Lee, Jae Guk Kim, Jae-Kwan Cha, Dae-Hyun Kim, Hyun-Wook Nah, Tai Hwan Park, Sang-Soon Park, Kyung Bok Lee, Jun Lee, Keun-Sik Hong, Yong-Jin Cho, Byung-Chul Lee, Kyung-Ho Yu, M Tags: Quality and Outcomes, Ischemic Stroke, Transient Ischemic Attack (TIA) Original Contributions Source Type: research

Pulmonary Embolism in Ischemic Stroke: Clinical Presentation, Risk Factors, and Outcome Stroke
Conclusions In this large cohort study, PE occurred in nearly 1% of AIS patients. PE was more common in patients with severe stroke, history of cancer, previous DVT/PE or acute DVT and associated with lower short- and long-term survival, greater disability, and longer length of stay.
Source: JAHA:Journal of the American Heart Association - November 25, 2013 Category: Cardiology Authors: Pongmoragot, J., Rabinstein, A. A., Nilanont, Y., Swartz, R. H., Zhou, L., Saposnik, G., The Investigators of the Registry of the Canadian Stroke Network (RCSN) and University of Toronto Stroke Program for the Stroke Outcomes Research Canada (SORCan [www. Tags: Stroke Source Type: research

Design and Validation of a Prehospital Stroke Scale to Predict Large Arterial Occlusion: The Rapid Arterial Occlusion Evaluation Scale Clinical Sciences
Conclusions— The RACE scale is a simple tool that can accurately assess stroke severity and identify patients with acute stroke with large artery occlusion at prehospital setting by medical emergency technicians.
Source: Stroke - December 23, 2013 Category: Neurology Authors: Perez de la Ossa, N., Carrera, D., Gorchs, M., Querol, M., Millan, M., Gomis, M., Dorado, L., Lopez-Cancio, E., Hernandez-Perez, M., Chicharro, V., Escalada, X., Jimenez, X., Davalos, A. Tags: Cerebrovascular disease/stroke, Acute Cerebral Infarction, Emergency treatment of Stroke Clinical Sciences Source Type: research

Clinical Scales Do Not Reliably Identify Acute Ischemic Stroke Patients With Large-Artery Occlusion Clinical Sciences
Conclusions— Using published cutoffs for triage would result in a loss of opportunity for ≥20% of patients with large-artery occlusion who would be inappropriately sent to a center lacking neurointerventional facilities. Conversely, using cutoffs reducing the false-negative rate to 10% would result in sending almost every patient to a comprehensive stroke center. Our findings, therefore, suggest that intracranial arterial imaging should be performed in all patients with acute ischemic stroke presenting within 6 hours of symptom onset.
Source: Stroke - May 22, 2016 Category: Neurology Authors: Turc, G., Maier, B., Naggara, O., Seners, P., Isabel, C., Tisserand, M., Raynouard, I., Edjlali, M., Calvet, D., Baron, J.-C., Mas, J.-L., Oppenheim, C. Tags: Magnetic Resonance Imaging (MRI), Revascularization, Cerebrovascular Disease/Stroke, Ischemic Stroke Clinical Sciences Source Type: research

Field Assessment Stroke Triage for Emergency Destination: A Simple and Accurate Prehospital Scale to Detect Large Vessel Occlusion Strokes Clinical Sciences
Conclusions— FAST-ED is a simple scale that if successfully validated in the field, it may be used by medical emergency professionals to identify LVOS in the prehospital setting enabling rapid triage of patients.
Source: Stroke - July 24, 2016 Category: Neurology Authors: Lima, F. O., Silva, G. S., Furie, K. L., Frankel, M. R., Lev, M. H., Camargo, E. C. S., Haussen, D. C., Singhal, A. B., Koroshetz, W. J., Smith, W. S., Nogueira, R. G. Tags: Revascularization, Cerebrovascular Disease/Stroke, Ischemic Stroke Clinical Sciences Source Type: research

Ischemic Stroke Clinical Sciences
Conclusions—Histological thrombus features vary significantly according to the underlying cause and may help to differentiate between cardioembolic and noncardioembolic stroke. In addition, our study supports the hypothesis that most cryptogenic strokes have a cardioembolic cause.
Source: Stroke - July 24, 2017 Category: Neurology Authors: Peter B. Sporns, Uta Hanning, Wolfram Schwindt, Aglae Velasco, Jens Minnerup, Tarek Zoubi, Walter Heindel, Astrid Jeibmann, Thomas Ulrich Niederstadt Tags: Angiography, Revascularization, Cerebrovascular Disease/Stroke, Ischemic Stroke, Embolism Original Contributions Source Type: research

Recanalization Modulates Association Between Blood Pressure and Functional Outcome in Acute Ischemic Stroke Clinical Sciences
Conclusions— Systemic BP in the first 24 hours after ischemic stroke influences 3-month clinical outcome. This association is dependent on the revascularization status.
Source: Stroke - May 22, 2016 Category: Neurology Authors: Martins, A. I., Sargento-Freitas, J., Silva, F., Jesus-Ribeiro, J., Correia, I., Gomes, J. P., Aguiar-Goncalves, M., Cardoso, L., Machado, C., Rodrigues, B., Santo, G. C., Cunha, L. Tags: High Blood Pressure, Hypertension, Cerebrovascular Procedures, Ischemic Stroke Clinical Sciences Source Type: research

Good Intracranial Collaterals Trump Poor ASPECTS (Alberta Stroke Program Early CT Score) for Intravenous Thrombolysis in Anterior Circulation Acute Ischemic Stroke Clinical Sciences
Conclusions— In patients with large and very large volume infarcts, good collaterals as measured by the ASPECTS-collaterals system is associated with improved outcomes and can help select patients for intravenous thrombolysis.
Source: Stroke - August 21, 2016 Category: Neurology Authors: Tan, B. Y. Q., Wan-Yee, K., Paliwal, P., Gopinathan, A., Nadarajah, M., Ting, E., Venketasubramanian, N., Seet, R. C. S., Chan, B. P. L., Teoh, H. L., Rathakrishnan, R., Sharma, V. K., Yeo, L. L. L. Tags: Cerebrovascular Disease/Stroke, Ischemic Stroke Clinical Sciences Source Type: research

Uric Acid Therapy Prevents Early Ischemic Stroke Progression Brief Report
Conclusions—UA therapy may prevent EIW after acute stroke in thrombolysed patients. Optimal access of UA to its molecular targets through appropriate collaterals may modify the magnitude of the neuroprotective effect.Clinical Trial Registration—URL: http://www.clinicaltrials.gov. Unique identifier: NCT00860366.
Source: Stroke - October 23, 2016 Category: Neurology Authors: Amaro, S., Laredo, C., Renu, A., Llull, L., Rudilosso, S., Obach, V., Urra, X., Planas, A. M., Chamorro, A. Tags: Cerebrovascular Disease/Stroke, Ischemic Stroke, Neuroprotectants Brief Reports Source Type: research

NOR-SASS (Norwegian Sonothrombolysis in Acute Stroke Study) Clinical Sciences
Conclusions—CEST is safe among unselected ischemic stroke patients with or without a visible occlusion on computed tomography angiography and with varying grades of clinical severity. There was, however, statistically no significant clinical effect of sonothrombolysis in this prematurely stopped trial.Clinical Trial Registration—URL: http://www.clinicaltrials.gov. Unique identifier: NCT01949961.
Source: Stroke - January 22, 2017 Category: Neurology Authors: Aliona Nacu, Christopher E. Kvistad, Halvor Naess, Halvor Oygarden, Nicola Logallo, Jorg Assmus, Ulrike Waȷe–Andreassen, Kathinka D. Kurz, Gesche Neckelmann, Lars Thomassen Tags: Clinical Studies, Ischemia, Cerebrovascular Disease/Stroke, Ischemic Stroke Original Contributions Source Type: research