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Specialty: Gastroenterology
Condition: Thrombosis

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Total 70 results found since Jan 2013.

Impaired coagulation, liver dysfunction and COVID-19: Discovering an intriguing relationship
World J Gastroenterol. 2022 Mar 21;28(11):1102-1112. doi: 10.3748/wjg.v28.i11.1102.ABSTRACTCoronavirus disease 2019 (COVID-19) is, at present, one of the most relevant global health problems. In the literature hepatic alterations have been described in COVID-19 patients, and they are mainly represented by worsening of underlying chronic liver disease leading to hepatic decompensation and liver failure with higher mortality. Several potential mechanisms used by severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) to cause liver damage have been hypothesized. COVID-19 primary liver injury is less common than secondar...
Source: World Journal of Gastroenterology - April 18, 2022 Category: Gastroenterology Authors: Damiano D'Ardes Andrea Boccatonda Giulio Cocco Stefano Fabiani Ilaria Rossi Marco Bucci Maria Teresa Guagnano Cosima Schiavone Francesco Cipollone Source Type: research

Impact of inflammatory bowel disease on hospital outcomes in acute ischemic stroke: a nationwide cohort study
ConclusionsUC and CD do not appear to be associated with a higher risk of mortality or increased healthcare usage in AIS. AIS risk assessment in patients with IBD is important but should be done in a similar fashion to the general population.
Source: International Journal of Colorectal Disease - July 14, 2021 Category: Gastroenterology Source Type: research

Fr127 PENTADECAPEPTIDE BPC 157 IN STROKE RATS COUNTERACTS STRESS GASTRIC LESIONS, THROMBOSIS AND INTRACRANIAL, PORTAL AND CAVAL HYPERTENSION, AND AORTAL HYPOTENSION
Source: Gastroenterology - May 1, 2021 Category: Gastroenterology Authors: Slaven Gojkovic, Jaksa Vukojevic, Ivan Krezic, Sanja Strbe, Hrvoje Vranes, Katarina Oroz, Luka Coric, Karol Simonji, Marijan Tepes, Eva Lovric, Anita Skrtic, Sven Seiwerth, Predrag Sikiric Tags: AGA Abstracts Source Type: research

Intestinal Ischemic Manifestations of COVID-19
We read with interest the article by Norsa et  al1 on intestinal ischemia in patients with coronavirus disease 2019 (COVID-19). They further highlight the coagulopathy known to cause vascular obstructions in patients with severe COVID-19, in whom microthrombi are typically found in the lung circulation; however, also myocardial infarction and ischemic stroke were reported, particularly in the late phase of the disease. The patients reported by Norsa et al had either small or large bowel ischemia, splenic infarct, or pulmonary thromboembolism, which were fatal in 4 of the 7 cases.
Source: Gastroenterology - December 29, 2020 Category: Gastroenterology Authors: Antonio Ponzetto, John Holton, Massimo Porta Tags: Correspondence Source Type: research

Algorithmic anticoagulation: streamlining the decision to hold and restart blood thinners in the periendoscopy period
The number and complexity of procedures performed by gastroenterologists are increasing in the United States.1,2 In addition, the number and complexity of antithrombotic agents are growing.3 These concurrent trends may lead to confusion among providers on the  appropriate management of these drugs during endoscopy. The skilled clinician must balance the risks of thrombosis, including myocardial infarction and stroke, against the risks of procedure-related hemorrhage, which can be potentially fatal.
Source: Gastrointestinal Endoscopy - November 20, 2019 Category: Gastroenterology Authors: Theodore W. James, Todd H. Baron Tags: Original article Source Type: research

Direct Oral Anticoagulants in Cirrhotic Patients: Current Evidence and Clinical Observations.
Authors: Elhosseiny S, Al Moussawi H, Chalhoub JM, Lafferty J, Deeb L Abstract The introduction of Direct Oral Anticoagulants (DOACs) to the pharmaceutical market provided patients and clinicians with novel convenient and safe options of anticoagulation. The use of this class of medications is currently limited to venous thromboembolic therapy and prophylaxis, in addition to stroke prophylaxis in patients with nonvalvular atrial fibrillation. Despite their altered hemostasis, patients with cirrhosis are thought to be in a procoagulant state and thus prone to thrombus formation. Patients with cirrhosis might benefit...
Source: Canadian Journal of Gastroenterology - February 24, 2019 Category: Gastroenterology Tags: Can J Gastroenterol Hepatol Source Type: research

Endoscopy in Patients on Antiplatelet Agents and Anticoagulants
Opinion statementManagement of patients on anticoagulant or antiplatelet therapy undergoing endoscopy presents a balance of risks between haemorrhage due to the procedure, and thrombosis due to discontinuation of antithrombotic therapy. Haemorrhage is usually controllable endoscopically, but thrombosis could, on occasion, result in myocardial infarction or stroke, with permanent disability or death. For elective procedures, there is adequate time to plan best management of antithrombotic therapy. International guidelines have been published, but recommendations are based on limited evidence and consultation with appropriat...
Source: Current Treatment Options in Gastroenterology - May 25, 2017 Category: Gastroenterology Source Type: research

Mo1086 Severity of Gastrointestinal Bleeding in Patients Treated With Direct-Acting Oral Anticoagulants (Doacs)
Direct-acting oral anticoagulants (DOACs), which have recently been approved for stroke prevention in non-valvular atrial fibrillation and treatment of venous thromboembolism, have become increasingly preferred over warfarin given their predictable pharmacodynamics and lack of required monitoring. DOACs have been shown to be associated with an increased frequency of gastrointestinal bleeding (GIB) compared to warfarin, but the severity of GIB in these patients is poorly understood.
Source: Gastrointestinal Endoscopy - April 28, 2017 Category: Gastroenterology Authors: Mark M. Brodie, Tyler Smith, Jill Newman, Don C. Rockey Tags: Monday – ASGE poster Source Type: research

Mo1074 Outcomes of Gastrointestinal Hemorrhage in the Setting of Novel Versus Traditional Antithrombotic Agents
The objective of our study was to compare outcomes among patients presenting with GI bleed that were prescribed novel versus traditional antithrombotic agents.
Source: Gastrointestinal Endoscopy - April 28, 2017 Category: Gastroenterology Authors: Jonathan I. Chang, Elizabeth Dong, Karl Kwok, Bechien U. Wu Tags: Monday – ASGE poster Source Type: research

Risk of Gastrointestinal Bleeding in Patients Taking Non-vitamin K Antagonist Oral Anticoagulants: a Systematic Review and Meta-analysis
Non-vitamin K antagonist oral anticoagulants (NOACs) are convenient and effective in prevention and treatment of venous thromboembolism and prevention of stroke in patients with atrial fibrillation. However, these drugs have been associated with increased risk of gastrointestinal (GI) bleeding. We conducted a systematic review and meta-analysis to determine the risk of GI bleeding in patients receiving these drugs.
Source: Clinical Gastroenterology and Hepatology - April 27, 2017 Category: Gastroenterology Authors: Corey S. Miller, Alastair Dorreen, Myriam Martel, Thao Huynh, Alan N. Barkun Source Type: research

Risk of Gastrointestinal Bleeding in Patients Taking Non –Vitamin K Antagonist Oral Anticoagulants: A Systematic Review and Meta-Analysis
Non –vitamin K antagonist oral anticoagulants (novel oral anticoagulants [NOACs]) are convenient and effective in the prevention and treatment of venous thromboembolism and the prevention of stroke in patients with atrial fibrillation. However, these drugs have been associated with an increased risk o f gastrointestinal (GI) bleeding. We conducted a systematic review and meta-analysis to determine the risk of GI bleeding in patients receiving these drugs.
Source: Clinical Gastroenterology and Hepatology - April 27, 2017 Category: Gastroenterology Authors: Corey S. Miller, Alastair Dorreen, Myriam Martel, Thao Huynh, Alan N. Barkun Source Type: research

Gastrointestinal bleeding in patients on novel oral anticoagulants: Risk, prevention and management.
Abstract Novel oral anticoagulants (NOACs), which include direct thrombin inhibitor (dabigatran) and direct factor Xa inhibitors (rivaroxaban, apixaban and edoxaban), are gaining popularity in the prevention of embolic stroke in non-valvular atrial fibrillation as well as in the prevention and treatment of venous thromboembolism. However, similar to traditional anticoagulants, NOACs have the side effects of bleeding, including gastrointestinal bleeding (GIB). Results from both randomized clinical trials and observations studies suggest that high-dose dabigatran (150 mg b.i.d), rivaroxaban and high-dose edoxaban (6...
Source: World Journal of Gastroenterology : WJG - March 21, 2017 Category: Gastroenterology Authors: Cheung KS, Leung WK Tags: World J Gastroenterol Source Type: research

Portal Vein Thrombosis and Stroke in a Patient With Tetralogy of Fallot: Erratum
No abstract available
Source: Journal of Pediatric Gastroenterology and Nutrition - February 25, 2016 Category: Gastroenterology Tags: Errata Source Type: research

Total hepatectomy and liver transplantation as a two-stage procedure for fulminant hepatic failure: A safe procedure in exceptional circumstances.
CONCLUSION: Two-stage liver transplantation represents a safe and potentially life-saving treatment for carefully selected exceptional cases of fulminant hepatic failure. PMID: 26855693 [PubMed - as supplied by publisher]
Source: World Journal of Hepatology - February 10, 2016 Category: Gastroenterology Tags: World J Hepatol Source Type: research